IMP

Process View

Mus musculus

9 genes annotated in mouse

Multi-species View

negative regulation of jun kinase activity

GO:0043508

Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of jun kinase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of jun kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Jun	Jun oncogene	0.999
Apc	adenomatosis polyposis coli	0.998
Trp53	transformation related protein 53	0.990	Mouse
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.950
Sfrp2	secreted frizzled-related protein 2	0.948
Pten	phosphatase and tensin homolog	0.930
Mapk14	mitogen-activated protein kinase 14	0.914
Fos	FBJ osteosarcoma oncogene	0.857
Axin1	axin 1	0.772
Mdm2	transformed mouse 3T3 cell double minute 2	0.701
Trp63	transformation related protein 63	0.698	Mouse
Sfrp1	secreted frizzled-related protein 1	0.664
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.658
Mapk9	mitogen-activated protein kinase 9	0.600	Fly
Klc1	kinesin light chain 1	0.527
Mapk8	mitogen-activated protein kinase 8	0.477	Fly
Emx1	empty spiracles homolog 1 (Drosophila)	0.451
Mapk1	mitogen-activated protein kinase 1	0.397
Gsk3b	glycogen synthase kinase 3 beta	0.337	Fly
Smad3	MAD homolog 3 (Drosophila)	0.296
Lrp6	low density lipoprotein receptor-related protein 6	0.230
Prkce	protein kinase C, epsilon	0.230
Trp73	transformation related protein 73	0.218
Psen1	presenilin 1	0.192
Gsta4	glutathione S-transferase, alpha 4	0.190	Mouse
Vangl2	vang-like 2 (van gogh, Drosophila)	0.185
Rhob	ras homolog gene family, member B	0.139
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.127
Hspa1b	heat shock protein 1B	0.112
Mdm4	transformed mouse 3T3 cell double minute 4	0.112
Skil	SKI-like	0.111
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.106
Gm3776	predicted gene 3776	0.093
Hspa8	heat shock protein 8	0.091
Rac1	RAS-related C3 botulinum substrate 1	0.086
Ccnd1	cyclin D1	0.075
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.075
Hsph1	heat shock 105kDa/110kDa protein 1	0.066
Klf6	Kruppel-like factor 6	0.065
App	amyloid beta (A4) precursor protein	0.060
Ier2	immediate early response 2	0.056
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.054
Atf3	activating transcription factor 3	0.051
Sfn	stratifin	0.050
Spag9	sperm associated antigen 9	0.049
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.048
Kif1b	kinesin family member 1B	0.045
Ces1d	carboxylesterase 1D	0.044
Ahsa2	AHA1, activator of heat shock protein ATPase homolog 2 (yeast)	0.043
Gstm1	glutathione S-transferase, mu 1	0.041
Klf7	Kruppel-like factor 7 (ubiquitous)	0.041
Vhl	von Hippel-Lindau tumor suppressor	0.039
Gli3	GLI-Kruppel family member GLI3	0.038
Vcl	vinculin	0.033
Lef1	lymphoid enhancer binding factor 1	0.032
Zfp36	zinc finger protein 36	0.032
Homer1	homer homolog 1 (Drosophila)	0.031
Ikbkg	inhibitor of kappaB kinase gamma	0.030
Mtmr1	myotubularin related protein 1	0.028
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.028
Gli2	GLI-Kruppel family member GLI2	0.027
Irf6	interferon regulatory factor 6	0.025
Map3k12	mitogen-activated protein kinase kinase kinase 12	0.025
Egr1	early growth response 1	0.024
Wnt5a	wingless-related MMTV integration site 5A	0.024
Errfi1	ERBB receptor feedback inhibitor 1	0.024
Gsta3	glutathione S-transferase, alpha 3	0.023	Mouse
Nsf	N-ethylmaleimide sensitive fusion protein	0.023
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.023
Smad7	MAD homolog 7 (Drosophila)	0.023
Klc2	kinesin light chain 2	0.022
Klf4	Kruppel-like factor 4 (gut)	0.021
Runx1	runt related transcription factor 1	0.021
Thbs1	thrombospondin 1	0.021
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.020
Aff1	AF4/FMR2 family, member 1	0.020
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.020
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.019
Il6st	interleukin 6 signal transducer	0.019
Atf2	activating transcription factor 2	0.019
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.019
Usp25	ubiquitin specific peptidase 25	0.018
Pbx1	pre B-cell leukemia transcription factor 1	0.018
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.017
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.017
Csnk1e	casein kinase 1, epsilon	0.017
Map2k4	mitogen-activated protein kinase kinase 4	0.017
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.017
Hhat	hedgehog acyltransferase	0.016
Mapk11	mitogen-activated protein kinase 11	0.016
Efnb2	ephrin B2	0.015
Numb	numb gene homolog (Drosophila)	0.015
Braf	Braf transforming gene	0.015
Prdx6	peroxiredoxin 6	0.015
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.015
Bhlhe40	basic helix-loop-helix family, member e40	0.015
Lrrk2	leucine-rich repeat kinase 2	0.014
Gstt1	glutathione S-transferase, theta 1	0.014
Cbr1	carbonyl reductase 1	0.014
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.014
Arc	activity regulated cytoskeletal-associated protein	0.014
Tgfbr1	transforming growth factor, beta receptor I	0.013
Nf2	neurofibromatosis 2	0.013
Myo10	myosin X	0.013
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.013
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.013
Rtn1	reticulon 1	0.013
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.012
Hspa1a	heat shock protein 1A	0.012
Aplp2	amyloid beta (A4) precursor-like protein 2	0.012
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.012
Ptk7	PTK7 protein tyrosine kinase 7	0.012
Foxp3	forkhead box P3	0.012
Epn1	epsin 1	0.011
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.011
Lrp4	low density lipoprotein receptor-related protein 4	0.011
Mpzl2	myelin protein zero-like 2	0.011
Hspa4l	heat shock protein 4 like	0.011
Dsg1a	desmoglein 1 alpha	0.011
Hr	hairless	0.011
Gripap1	GRIP1 associated protein 1	0.011
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.011
Rb1	retinoblastoma 1	0.011
Yap1	yes-associated protein 1	0.011
Ctnna1	catenin (cadherin associated protein), alpha 1	0.011
Ahr	aryl-hydrocarbon receptor	0.010
Mapkapk2	MAP kinase-activated protein kinase 2	0.010
Sertad1	SERTA domain containing 1	0.010
Kit	kit oncogene	0.010