IMP

Process View

Mus musculus

15 genes annotated in mouse

sertoli cell development

The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sertoli cell development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "sertoli cell development" (in gray)

Name	Description	Probability	Func Analog Organism
Esr1	estrogen receptor 1 (alpha)	0.925	Rat
Fgfr2	fibroblast growth factor receptor 2	0.792
Apc	adenomatosis polyposis coli	0.732
Pten	phosphatase and tensin homolog	0.726
Kiss1	KiSS-1 metastasis-suppressor	0.644
Amhr2	anti-Mullerian hormone type 2 receptor	0.607
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.603
Gli3	GLI-Kruppel family member GLI3	0.599
Ar	androgen receptor	0.582
Pax2	paired box gene 2	0.540
Pax8	paired box gene 8	0.528
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.477
Ntf3	neurotrophin 3	0.460
Ghr	growth hormone receptor	0.371
Lhx3	LIM homeobox protein 3	0.287
Kiss1r	KISS1 receptor	0.272
Isl1	ISL1 transcription factor, LIM/homeodomain	0.231
Rb1	retinoblastoma 1	0.231
Shh	sonic hedgehog	0.230
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.220	Mouse
Pax6	paired box gene 6	0.211
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.210
Emx2	empty spiracles homolog 2 (Drosophila)	0.199
Ptgs2	prostaglandin-endoperoxide synthase 2	0.194
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.181
Lepr	leptin receptor	0.169
Foxc1	forkhead box C1	0.166
Bdnf	brain derived neurotrophic factor	0.143
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.134
Pitx2	paired-like homeodomain transcription factor 2	0.133
Egr1	early growth response 1	0.125	Mouse
Smc1a	structural maintenance of chromosomes 1A	0.124
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.124
Nos3	nitric oxide synthase 3, endothelial cell	0.121
Sox2	SRY-box containing gene 2	0.115	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.115
Ret	ret proto-oncogene	0.112
Nog	noggin	0.110
Cga	glycoprotein hormones, alpha subunit	0.108
Fgf10	fibroblast growth factor 10	0.106
Fgfr3	fibroblast growth factor receptor 3	0.100
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.093
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.092
Lhx9	LIM homeobox protein 9	0.091
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.087
Kit	kit oncogene	0.085
Nrg1	neuregulin 1	0.083
Bmp4	bone morphogenetic protein 4	0.081
Pou5f1	POU domain, class 5, transcription factor 1	0.081
Tcfap2a	transcription factor AP-2, alpha	0.080
Nab2	Ngfi-A binding protein 2	0.076
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.075
Emx1	empty spiracles homolog 1 (Drosophila)	0.073
Meox2	mesenchyme homeobox 2	0.072
Fos	FBJ osteosarcoma oncogene	0.070
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.065
Efnb2	ephrin B2	0.060
Nf1	neurofibromatosis 1	0.059
Gdnf	glial cell line derived neurotrophic factor	0.059
She	src homology 2 domain-containing transforming protein E	0.057
Drd2	dopamine receptor D2	0.056
Thrb	thyroid hormone receptor beta	0.053
Hhex	hematopoietically expressed homeobox	0.053
Otx1	orthodenticle homolog 1 (Drosophila)	0.052
Cd44	CD44 antigen	0.051
Duox2	dual oxidase 2	0.051
Plekha5	pleckstrin homology domain containing, family A member 5	0.050
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.048
Kl	klotho	0.045
Pax3	paired box gene 3	0.044
Gata3	GATA binding protein 3	0.044
Rarb	retinoic acid receptor, beta	0.043
Socs3	suppressor of cytokine signaling 3	0.042
Zeb1	zinc finger E-box binding homeobox 1	0.041
Tgfb2	transforming growth factor, beta 2	0.040
Foxc2	forkhead box C2	0.039
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.039
Vgf	VGF nerve growth factor inducible	0.038
Amh	anti-Mullerian hormone	0.038
Tbx10	T-box 10	0.037
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.037
Sall4	sal-like 4 (Drosophila)	0.035
Otx2	orthodenticle homolog 2 (Drosophila)	0.035
Ahr	aryl-hydrocarbon receptor	0.034
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.034
Meox1	mesenchyme homeobox 1	0.033
Sox11	SRY-box containing gene 11	0.033	Mouse
Inha	inhibin alpha	0.032
Chd7	chromodomain helicase DNA binding protein 7	0.032
Junb	Jun-B oncogene	0.031
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.031
Hand1	heart and neural crest derivatives expressed transcript 1	0.029
Col2a1	collagen, type II, alpha 1	0.029
Egr2	early growth response 2	0.029	Mouse
Tcfap2c	transcription factor AP-2, gamma	0.029
Alx1	ALX homeobox 1	0.028
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.028
Jag1	jagged 1	0.027
Foxf2	forkhead box F2	0.027
Pitx1	paired-like homeodomain transcription factor 1	0.027
Hoxa1	homeobox A1	0.027
Ccl2	chemokine (C-C motif) ligand 2	0.026
Eya1	eyes absent 1 homolog (Drosophila)	0.026
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.026
Hoxd13	homeobox D13	0.026
Tal1	T-cell acute lymphocytic leukemia 1	0.025
Mmp9	matrix metallopeptidase 9	0.025
Gli2	GLI-Kruppel family member GLI2	0.024
Nos2	nitric oxide synthase 2, inducible	0.024
Thoc2	THO complex 2	0.024
Pou3f3	POU domain, class 3, transcription factor 3	0.023
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.023
Bglap	bone gamma carboxyglutamate protein	0.023
Lef1	lymphoid enhancer binding factor 1	0.023
Foxl2	forkhead box L2	0.023
Dhh	desert hedgehog	0.023
Lhx1	LIM homeobox protein 1	0.023
Zfp445	zinc finger protein 445	0.023
Gnrhr	gonadotropin releasing hormone receptor	0.023
Col4a3	collagen, type IV, alpha 3	0.023
Trp63	transformation related protein 63	0.022
Fshr	follicle stimulating hormone receptor	0.022
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.022
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.021
Acan	aggrecan	0.021
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.021
Adam17	a disintegrin and metallopeptidase domain 17	0.021
Vangl2	vang-like 2 (van gogh, Drosophila)	0.021
Wnt6	wingless-related MMTV integration site 6	0.020
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.020
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.020
Hoxa10	homeobox A10	0.020
Insm1	insulinoma-associated 1	0.020
Fgf8	fibroblast growth factor 8	0.020
Lep	leptin	0.020
Xrn1	5'-3' exoribonuclease 1	0.020
Col11a1	collagen, type XI, alpha 1	0.019
Cldn5	claudin 5	0.019
Hes1	hairy and enhancer of split 1 (Drosophila)	0.019
Pou4f2	POU domain, class 4, transcription factor 2	0.019
Nkx2-1	NK2 homeobox 1	0.019
Tcf21	transcription factor 21	0.019
Lmx1a	LIM homeobox transcription factor 1 alpha	0.019
Nab1	Ngfi-A binding protein 1	0.019
Tyro3	TYRO3 protein tyrosine kinase 3	0.018
Alx4	aristaless-like homeobox 4	0.018
Atoh7	atonal homolog 7 (Drosophila)	0.018
Tbx3	T-box 3	0.018
Epha4	Eph receptor A4	0.017
Inhbb	inhibin beta-B	0.017
Gata6	GATA binding protein 6	0.017
Itm2c	integral membrane protein 2C	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.017
Jun	Jun oncogene	0.016
Fosb	FBJ osteosarcoma oncogene B	0.016
Bmper	BMP-binding endothelial regulator	0.016
Prlr	prolactin receptor	0.016
Alx3	aristaless-like homeobox 3	0.016
Fstl1	follistatin-like 1	0.016
Rsf1	remodeling and spacing factor 1	0.016
Nhlh2	nescient helix loop helix 2	0.016
Efna4	ephrin A4	0.016
Samm50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.016
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.016
2810474O19Rik	RIKEN cDNA 2810474O19 gene	0.015
Timp1	tissue inhibitor of metalloproteinase 1	0.015
Sox4	SRY-box containing gene 4	0.015	Mouse
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.015
Wnt4	wingless-related MMTV integration site 4	0.015
Zfp503	zinc finger protein 503	0.015
Arc	activity regulated cytoskeletal-associated protein	0.015
Hes5	hairy and enhancer of split 5 (Drosophila)	0.015
Rnf126	ring finger protein 126	0.015
Fgf3	fibroblast growth factor 3	0.015
Bbx	bobby sox homolog (Drosophila)	0.015
Vegfa	vascular endothelial growth factor A	0.015
Rictor	RPTOR independent companion of MTOR, complex 2	0.014
Gas1	growth arrest specific 1	0.014
Capn6	calpain 6	0.014
Padi1	peptidyl arginine deiminase, type I	0.014
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.014
Pou3f1	POU domain, class 3, transcription factor 1	0.014
Runx2	runt related transcription factor 2	0.014
Nrk	Nik related kinase	0.014
Osr1	odd-skipped related 1 (Drosophila)	0.013
Pthlh	parathyroid hormone-like peptide	0.013
Wnt9b	wingless-type MMTV integration site 9B	0.013
Fgf4	fibroblast growth factor 4	0.013
Stat3	signal transducer and activator of transcription 3	0.013
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.013
Tg	thyroglobulin	0.013
Pbx1	pre B-cell leukemia transcription factor 1	0.013
Ier5l	immediate early response 5-like	0.013
Nos1	nitric oxide synthase 1, neuronal	0.013
Hoxd8	homeobox D8	0.013
Nkx6-1	NK6 homeobox 1	0.013
Nrtn	neurturin	0.013
Arx	aristaless related homeobox	0.012
Hoxc8	homeobox C8	0.012
Plac1	placental specific protein 1	0.012
Ebf3	early B-cell factor 3	0.012
Star	steroidogenic acute regulatory protein	0.012
Dusp9	dual specificity phosphatase 9	0.012
Efna1	ephrin A1	0.012
Lmx1b	LIM homeobox transcription factor 1 beta	0.012
Hoxa4	homeobox A4	0.012
Wwtr1	WW domain containing transcription regulator 1	0.012
Dmrt1	doublesex and mab-3 related transcription factor 1	0.012
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.012
A230046K03Rik	RIKEN cDNA A230046K03 gene	0.012
Chd4	chromodomain helicase DNA binding protein 4	0.012
Braf	Braf transforming gene	0.012
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
Sall1	sal-like 1 (Drosophila)	0.012
Erbb2ip	Erbb2 interacting protein	0.012
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.012
Pgr	progesterone receptor	0.012
Robo3	roundabout homolog 3 (Drosophila)	0.012
Nanog	Nanog homeobox	0.012
Ctnnb1	catenin (cadherin associated protein), beta 1	0.012
Igf1	insulin-like growth factor 1	0.011
Aplnr	apelin receptor	0.011
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.011
Sall3	sal-like 3 (Drosophila)	0.011
Msx1	homeobox, msh-like 1	0.011
Trp53	transformation related protein 53	0.011
Foxg1	forkhead box G1	0.011
Hesx1	homeobox gene expressed in ES cells	0.011
Cd151	CD151 antigen	0.011
Zfpm1	zinc finger protein, multitype 1	0.011
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
Fhl3	four and a half LIM domains 3	0.011
BC005561	cDNA sequence BC005561	0.011
BC057022	cDNA sequence BC057022	0.011
Lin28a	lin-28 homolog A (C. elegans)	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.011
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.011
Bnc1	basonuclin 1	0.011
Hoxa11	homeobox A11	0.011
Dst	dystonin	0.011
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.011
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.011
Apoe	apolipoprotein E	0.011
4930579J09Rik	RIKEN cDNA 4930579J09 gene	0.010
Hoxd10	homeobox D10	0.010
Rest	RE1-silencing transcription factor	0.010
Ubxn1	UBX domain protein 1	0.010
Efs	embryonal Fyn-associated substrate	0.010
Ptprb	protein tyrosine phosphatase, receptor type, B	0.010
Phox2b	paired-like homeobox 2b	0.010
Bmp7	bone morphogenetic protein 7	0.010
Zfx	zinc finger protein X-linked	0.010
Edar	ectodysplasin-A receptor	0.010
Dusp1	dual specificity phosphatase 1	0.010
Rbm5	RNA binding motif protein 5	0.010
Rasip1	Ras interacting protein 1	0.010
Zic1	zinc finger protein of the cerebellum 1	0.010
Ren1	renin 1 structural	0.010
Ankhd1	ankyrin repeat and KH domain containing 1	0.010