IMP

Process View

Mus musculus

3 genes annotated in mouse

regulation of mitochondrial fission

Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mitochondrial fission"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mitochondrial fission" (in gray)

Name	Description	Probability	Func Analog Organism
Lrrk2	leucine-rich repeat kinase 2	0.785
Bak1	BCL2-antagonist/killer 1	0.778
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.615
Mfn2	mitofusin 2	0.523	Fly
Ptp4a1	protein tyrosine phosphatase 4a1	0.485
Hccs	holocytochrome c synthetase	0.378
Atl2	atlastin GTPase 2	0.348
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.292
Nampt	nicotinamide phosphoribosyltransferase	0.277
Kpna1	karyopherin (importin) alpha 1	0.248
Ndrg2	N-myc downstream regulated gene 2	0.206
Sod2	superoxide dismutase 2, mitochondrial	0.179
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)	0.178
Rab18	RAB18, member RAS oncogene family	0.171
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.171
Sncaip	synuclein, alpha interacting protein (synphilin)	0.142
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.138
Isca1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae)	0.138
Tcta	T-cell leukemia translocation altered gene	0.114
Hbs1l	Hbs1-like (S. cerevisiae)	0.111
March5	membrane-associated ring finger (C3HC4) 5	0.110	Human
Pick1	protein interacting with C kinase 1	0.109
Ugp2	UDP-glucose pyrophosphorylase 2	0.106
Tchp	trichoplein, keratin filament binding	0.103
Afg3l2	AFG3(ATPase family gene 3)-like 2 (yeast)	0.101
Cycs	cytochrome c, somatic	0.099
Nos3	nitric oxide synthase 3, endothelial cell	0.096
Ghitm	growth hormone inducible transmembrane protein	0.088
Uba3	ubiquitin-like modifier activating enzyme 3	0.085
Pgk1	phosphoglycerate kinase 1	0.079
Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	0.078
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.077
Snca	synuclein, alpha	0.071
Hspa9	heat shock protein 9	0.068
Egln1	EGL nine homolog 1 (C. elegans)	0.068
Slc30a9	solute carrier family 30 (zinc transporter), member 9	0.067
Dld	dihydrolipoamide dehydrogenase	0.064
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.059
Lpin1	lipin 1	0.058
Eif3j	eukaryotic translation initiation factor 3, subunit J	0.053
Dcaf8	DDB1 and CUL4 associated factor 8	0.051
Mfn1	mitofusin 1	0.050	Fly
Opa1	optic atrophy 1 homolog (human)	0.050
Sh3gl2	SH3-domain GRB2-like 2	0.047
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.044
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.043
Dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.043
Gkap1	G kinase anchoring protein 1	0.042
Mlycd	malonyl-CoA decarboxylase	0.040
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.040
Trappc10	trafficking protein particle complex 10	0.040
Bnip3	BCL2/adenovirus E1B interacting protein 3	0.039	Human
Gbe1	glucan (1,4-alpha-), branching enzyme 1	0.036
Ubr3	ubiquitin protein ligase E3 component n-recognin 3	0.035
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.035
Etfdh	electron transferring flavoprotein, dehydrogenase	0.034
Gphn	gephyrin	0.034
Rcl1	RNA terminal phosphate cyclase-like 1	0.032
Acadl	acyl-Coenzyme A dehydrogenase, long-chain	0.032
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.032
Iscu	IscU iron-sulfur cluster scaffold homolog (E. coli)	0.032
Endog	endonuclease G	0.032
Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.031
Slc25a46	solute carrier family 25, member 46	0.030
Ccng1	cyclin G1	0.030
Adipor1	adiponectin receptor 1	0.030
Pdk1	pyruvate dehydrogenase kinase, isoenzyme 1	0.029
Pgm2	phosphoglucomutase 2	0.029
Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	0.029
2310044G17Rik	RIKEN cDNA 2310044G17 gene	0.027
Mul1	mitochondrial ubiquitin ligase activator of NFKB 1	0.027
Nkiras1	NFKB inhibitor interacting Ras-like protein 1	0.026
Vdac2	voltage-dependent anion channel 2	0.026
Ranbp9	RAN binding protein 9	0.026
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.025
Dnajb2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.025
Becn1	beclin 1, autophagy related	0.025
Rnf11	ring finger protein 11	0.025
2310061I04Rik	RIKEN cDNA 2310061I04 gene	0.025
Klf9	Kruppel-like factor 9	0.024
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.023
Ryr2	ryanodine receptor 2, cardiac	0.023
Akap1	A kinase (PRKA) anchor protein 1	0.023
Cul2	cullin 2	0.022
Ccrn4l	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	0.022
1110008F13Rik	RIKEN cDNA 1110008F13 gene	0.022
Serinc1	serine incorporator 1	0.022
Fam134b	family with sequence similarity 134, member B	0.022
Gde1	glycerophosphodiester phosphodiesterase 1	0.021
Scoc	short coiled-coil protein	0.021
Acsl1	acyl-CoA synthetase long-chain family member 1	0.021
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.021
Mkrn2	makorin, ring finger protein, 2	0.021
1810026J23Rik	RIKEN cDNA 1810026J23 gene	0.020
Usp2	ubiquitin specific peptidase 2	0.020
Lrpprc	leucine-rich PPR-motif containing	0.020
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.020
Zscan2	zinc finger and SCAN domain containing 2	0.019
Vdac1	voltage-dependent anion channel 1	0.019
Adck3	aarF domain containing kinase 3	0.019
Pex11a	peroxisomal biogenesis factor 11 alpha	0.018
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.018
Me1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.018
Snta1	syntrophin, acidic 1	0.017
Golph3	golgi phosphoprotein 3	0.017
Blcap	bladder cancer associated protein homolog (human)	0.017
Ubxn2a	UBX domain protein 2A	0.016
Hspd1	heat shock protein 1 (chaperonin)	0.016
Sord	sorbitol dehydrogenase	0.016
Grsf1	G-rich RNA sequence binding factor 1	0.016
Rab3ip	RAB3A interacting protein	0.016
Prepl	prolyl endopeptidase-like	0.016
Fam73b	family with sequence similarity 73, member B	0.016
Snx10	sorting nexin 10	0.016
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.016
Bhlhe40	basic helix-loop-helix family, member e40	0.016
Tex2	testis expressed gene 2	0.016
Fbxo8	F-box protein 8	0.015
Timm8a1	translocase of inner mitochondrial membrane 8 homolog a1 (yeast)	0.015
Mettl7a1	methyltransferase like 7A1	0.015
Pfdn5	prefoldin 5	0.015
Ppara	peroxisome proliferator activated receptor alpha	0.015
5730403B10Rik	RIKEN cDNA 5730403B10 gene	0.015
Ndufa10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10	0.015
1810019N24Rik	RIKEN cDNA 1810019N24 gene	0.015
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.015
Glul	glutamate-ammonia ligase (glutamine synthetase)	0.015
Hibadh	3-hydroxyisobutyrate dehydrogenase	0.015
Plin4	perilipin 4	0.014
Meig1	meiosis expressed gene 1	0.014
Mut	methylmalonyl-Coenzyme A mutase	0.014
Clcn3	chloride channel 3	0.014
Pnpla2	patatin-like phospholipase domain containing 2	0.014
Wbp2	WW domain binding protein 2	0.014
1300001I01Rik	RIKEN cDNA 1300001I01 gene	0.014
Klf15	Kruppel-like factor 15	0.014
D17Wsu92e	DNA segment, Chr 17, Wayne State University 92, expressed	0.014
Kctd9	potassium channel tetramerisation domain containing 9	0.014
Ggnbp1	gametogenetin binding protein 1	0.014
6330409N04Rik	RIKEN cDNA 6330409N04 gene	0.014
Atg9a	autophagy-related 9A (yeast)	0.014
Rrn3	RRN3 RNA polymerase I transcription factor homolog (yeast)	0.014
Wdtc1	WD and tetratricopeptide repeats 1	0.014
Nudt19	nudix (nucleoside diphosphate linked moiety X)-type motif 19	0.014
Lpl	lipoprotein lipase	0.014
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.014
Acadvl	acyl-Coenzyme A dehydrogenase, very long chain	0.013
Gfm1	G elongation factor, mitochondrial 1	0.013
Mcart1	mitochondrial carrier triple repeat 1	0.013
Ankrd28	ankyrin repeat domain 28	0.013
Cry2	cryptochrome 2 (photolyase-like)	0.013
Hsdl2	hydroxysteroid dehydrogenase like 2	0.013
Adcy9	adenylate cyclase 9	0.013
Tor1aip2	torsin A interacting protein 2	0.013
Arih1	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)	0.013
Sik3	SIK family kinase 3	0.013
Nme5	non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)	0.013
Tada2b	transcriptional adaptor 2B	0.013
1810021B22Rik	RIKEN cDNA 1810021B22 gene	0.013
Pla2g12a	phospholipase A2, group XIIA	0.013
En1	engrailed 1	0.013
Etfa	electron transferring flavoprotein, alpha polypeptide	0.013
Lias	lipoic acid synthetase	0.013
Phtf2	putative homeodomain transcription factor 2	0.012
Cnst	consortin, connexin sorting protein	0.012
Cox10	COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)	0.012
Lap3	leucine aminopeptidase 3	0.012
D16H22S680E	DNA segment, Chr 16, human D22S680E, expressed	0.012
Dpm1	dolichol-phosphate (beta-D) mannosyltransferase 1	0.012
Nploc4	nuclear protein localization 4 homolog (S. cerevisiae)	0.012
Dpp9	dipeptidylpeptidase 9	0.012
Fam120a	family with sequence similarity 120, member A	0.012
Kpna3	karyopherin (importin) alpha 3	0.012
Tprgl	transformation related protein 63 regulated like	0.012
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.012
Dgat2	diacylglycerol O-acyltransferase 2	0.012
Ei24	etoposide induced 2.4 mRNA	0.011
Ldhb	lactate dehydrogenase B	0.011
Wfs1	Wolfram syndrome 1 homolog (human)	0.011
Rad23b	RAD23b homolog (S. cerevisiae)	0.011
D9Ertd402e	DNA segment, Chr 9, ERATO Doi 402, expressed	0.011
Slc16a1	solute carrier family 16 (monocarboxylic acid transporters), member 1	0.011
Slc25a33	solute carrier family 25, member 33	0.011
Nudt18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	0.011
Sec61a2	Sec61, alpha subunit 2 (S. cerevisiae)	0.011
Fitm2	fat storage-inducing transmembrane protein 2	0.011
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.011
March2	membrane-associated ring finger (C3HC4) 2	0.011
Ubqln4	ubiquilin 4	0.011
Pkp4	plakophilin 4	0.011
Gsk3a	glycogen synthase kinase 3 alpha	0.010
Optn	optineurin	0.010
Rab10	RAB10, member RAS oncogene family	0.010
Kif2a	kinesin family member 2A	0.010
9130011J15Rik	RIKEN cDNA 9130011J15 gene	0.010
Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1	0.010
Slmap	sarcolemma associated protein	0.010
Crat	carnitine acetyltransferase	0.010
Acacb	acetyl-Coenzyme A carboxylase beta	0.010