IMP
Process View
negative regulation of epidermal cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of epidermal cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.999 | ||
| Shh | sonic hedgehog | 0.989 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.961 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.953 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.940 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.934 | ||
| Psen1 | presenilin 1 | 0.923 | ||
| Jag1 | jagged 1 | 0.921 | Mouse | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.921 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.899 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.853 | ||
| Sox2 | SRY-box containing gene 2 | 0.837 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.798 | ||
| Rb1 | retinoblastoma 1 | 0.728 | ||
| Foxg1 | forkhead box G1 | 0.672 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.665 | ||
| Pax3 | paired box gene 3 | 0.627 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.590 | ||
| Foxc1 | forkhead box C1 | 0.582 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.546 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.523 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.427 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.414 | ||
| Nog | noggin | 0.400 | ||
| Efnb2 | ephrin B2 | 0.348 | ||
| Prrx1 | paired related homeobox 1 | 0.330 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.272 | ||
| Jag2 | jagged 2 | 0.263 | Mouse | |
| Jarid2 | jumonji, AT rich interactive domain 2 | 0.234 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.232 | ||
| Pten | phosphatase and tensin homolog | 0.231 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.215 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.209 | ||
| Fgf8 | fibroblast growth factor 8 | 0.202 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.194 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.183 | ||
| Dlx5 | distal-less homeobox 5 | 0.169 | ||
| Sox9 | SRY-box containing gene 9 | 0.161 | ||
| Foxc2 | forkhead box C2 | 0.161 | ||
| Smo | smoothened homolog (Drosophila) | 0.146 | ||
| Stk38 | serine/threonine kinase 38 | 0.142 | ||
| Pax6 | paired box gene 6 | 0.140 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.139 | ||
| Trp73 | transformation related protein 73 | 0.125 | Mouse | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.119 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.108 | ||
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.100 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.100 | ||
| Prrx2 | paired related homeobox 2 | 0.095 | ||
| Ptf1a | pancreas specific transcription factor, 1a | 0.094 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.091 | ||
| Zg16 | zymogen granule protein 16 | 0.091 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.089 | ||
| Trp63 | transformation related protein 63 | 0.079 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.077 | ||
| 2210010C04Rik | RIKEN cDNA 2210010C04 gene | 0.076 | ||
| Cdx2 | caudal type homeobox 2 | 0.064 | ||
| Tbx1 | T-box 1 | 0.061 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.061 | ||
| Rbbp4 | retinoblastoma binding protein 4 | 0.059 | ||
| Fgf10 | fibroblast growth factor 10 | 0.058 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.058 | ||
| Gsc | goosecoid homeobox | 0.058 | ||
| Reg2 | regenerating islet-derived 2 | 0.053 | Mouse | |
| Meox2 | mesenchyme homeobox 2 | 0.053 | ||
| Reg3b | regenerating islet-derived 3 beta | 0.044 | Mouse | |
| Ins1 | insulin I | 0.044 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.042 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.041 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.040 | Mouse | |
| Egfr | epidermal growth factor receptor | 0.039 | ||
| Etv4 | ets variant gene 4 (E1A enhancer binding protein, E1AF) | 0.037 | ||
| Gata4 | GATA binding protein 4 | 0.037 | ||
| Cpa1 | carboxypeptidase A1 | 0.036 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.036 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.035 | ||
| Sycn | syncollin | 0.034 | ||
| Ins2 | insulin II | 0.034 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.034 | ||
| Mtf2 | metal response element binding transcription factor 2 | 0.032 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.031 | ||
| Reg3d | regenerating islet-derived 3 delta | 0.028 | Mouse | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.028 | ||
| Hoxa13 | homeobox A13 | 0.027 | ||
| Tbx3 | T-box 3 | 0.027 | ||
| Pax9 | paired box gene 9 | 0.027 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.027 | ||
| Sp6 | trans-acting transcription factor 6 | 0.026 | ||
| Hes3 | hairy and enhancer of split 3 (Drosophila) | 0.026 | Mouse | |
| Gata3 | GATA binding protein 3 | 0.024 | ||
| Fgf15 | fibroblast growth factor 15 | 0.024 | ||
| Eng | endoglin | 0.023 | ||
| Srrm4 | serine/arginine repetitive matrix 4 | 0.023 | ||
| Efnb1 | ephrin B1 | 0.023 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.023 | ||
| Reg3a | regenerating islet-derived 3 alpha | 0.023 | ||
| Ptch1 | patched homolog 1 | 0.023 | ||
| Pax1 | paired box gene 1 | 0.022 | ||
| Reg1 | regenerating islet-derived 1 | 0.022 | Mouse | |
| Ctrb1 | chymotrypsinogen B1 | 0.022 | ||
| Gucy2c | guanylate cyclase 2c | 0.022 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.022 | ||
| Nrarp | Notch-regulated ankyrin repeat protein | 0.021 | ||
| Tlx3 | T-cell leukemia, homeobox 3 | 0.021 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.021 | ||
| Chrd | chordin | 0.021 | ||
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.021 | ||
| Clps | colipase, pancreatic | 0.020 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.020 | ||
| Dlx2 | distal-less homeobox 2 | 0.020 | ||
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.020 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.019 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.018 | ||
| Krt14 | keratin 14 | 0.018 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.017 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.017 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.017 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.017 | ||
| Gata6 | GATA binding protein 6 | 0.017 | ||
| Hoxc9 | homeobox C9 | 0.017 | ||
| Ms4a10 | membrane-spanning 4-domains, subfamily A, member 10 | 0.017 | ||
| Dlx1 | distal-less homeobox 1 | 0.017 | ||
| Mmp7 | matrix metallopeptidase 7 | 0.016 | ||
| Eed | embryonic ectoderm development | 0.016 | ||
| Mnx1 | motor neuron and pancreas homeobox 1 | 0.016 | ||
| Cela3b | chymotrypsin-like elastase family, member 3B | 0.016 | ||
| Aebp2 | AE binding protein 2 | 0.016 | ||
| Rtn4r | reticulon 4 receptor | 0.016 | ||
| Pnliprp2 | pancreatic lipase-related protein 2 | 0.016 | ||
| Edn3 | endothelin 3 | 0.016 | ||
| Wnt11 | wingless-related MMTV integration site 11 | 0.016 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.015 | ||
| Hr | hairless | 0.015 | ||
| Muc13 | mucin 13, epithelial transmembrane | 0.015 | ||
| Defa-rs2 | defensin, alpha, related sequence 2 | 0.015 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.015 | ||
| Dmbt1 | deleted in malignant brain tumors 1 | 0.015 | ||
| Msx1 | homeobox, msh-like 1 | 0.015 | Mouse | |
| Amelx | amelogenin X chromosome | 0.015 | ||
| Tcf15 | transcription factor 15 | 0.015 | ||
| Lhx3 | LIM homeobox protein 3 | 0.014 | ||
| Arx | aristaless related homeobox | 0.014 | ||
| Msgn1 | mesogenin 1 | 0.014 | ||
| Runx1 | runt related transcription factor 1 | 0.014 | ||
| Alx4 | aristaless-like homeobox 4 | 0.014 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.014 | ||
| Pvrl1 | poliovirus receptor-related 1 | 0.014 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.014 | ||
| Gp2 | glycoprotein 2 (zymogen granule membrane) | 0.014 | ||
| Rarg | retinoic acid receptor, gamma | 0.013 | ||
| Neurl1a | neuralized homolog 1A (Drosophila) | 0.013 | ||
| Tff2 | trefoil factor 2 (spasmolytic protein 1) | 0.013 | ||
| Apoe | apolipoprotein E | 0.013 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.013 | ||
| Plac1 | placental specific protein 1 | 0.013 | ||
| Ptch2 | patched homolog 2 | 0.013 | ||
| Cela2a | chymotrypsin-like elastase family, member 2A | 0.013 | ||
| Sox11 | SRY-box containing gene 11 | 0.013 | ||
| Uncx | UNC homeobox | 0.013 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.013 | ||
| Pax4 | paired box gene 4 | 0.013 | ||
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.012 | ||
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.012 | ||
| Nodal | nodal | 0.012 | ||
| Rxra | retinoid X receptor alpha | 0.012 | ||
| Sfn | stratifin | 0.012 | ||
| En1 | engrailed 1 | 0.012 | ||
| Ctrc | chymotrypsin C (caldecrin) | 0.011 | ||
| Irf6 | interferon regulatory factor 6 | 0.011 | ||
| Zbtb7c | zinc finger and BTB domain containing 7C | 0.011 | ||
| Psen2 | presenilin 2 | 0.011 | ||
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.011 | ||
| Yap1 | yes-associated protein 1 | 0.011 | ||
| Reg3g | regenerating islet-derived 3 gamma | 0.011 | ||
| Lama5 | laminin, alpha 5 | 0.011 | ||
| Gip | gastric inhibitory polypeptide | 0.011 | ||
| Efna4 | ephrin A4 | 0.011 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.010 | Mouse | |
| Slc22a12 | solute carrier family 22 (organic anion/cation transporter), member 12 | 0.010 | ||
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.010 | ||
| Mycl1 | v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) | 0.010 | ||
| Prss3 | protease, serine, 3 | 0.010 |