IMP
Process View
renal system process involved in regulation of blood volume
A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.882 | ||
| Kdr | kinase insert domain protein receptor | 0.827 | ||
| Ren1 | renin 1 structural | 0.416 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.244 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.243 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.220 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.219 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.178 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.173 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.140 | ||
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.137 | ||
| Grxcr1 | glutaredoxin, cysteine rich 1 | 0.134 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.130 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.130 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.117 | ||
| Cd151 | CD151 antigen | 0.104 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.104 | ||
| Myo15 | myosin XV | 0.098 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.095 | ||
| Mb | myoglobin | 0.095 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.094 | Mouse | |
| Agtr1a | angiotensin II receptor, type 1a | 0.092 | ||
| Hoxa10 | homeobox A10 | 0.092 | ||
| Wnk4 | WNK lysine deficient protein kinase 4 | 0.085 | ||
| Cdh5 | cadherin 5 | 0.083 | ||
| Cav1 | caveolin 1, caveolae protein | 0.079 | ||
| Ush1c | Usher syndrome 1C homolog (human) | 0.076 | ||
| Tjp1 | tight junction protein 1 | 0.074 | ||
| Umod | uromodulin | 0.054 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.053 | ||
| Apoe | apolipoprotein E | 0.052 | ||
| Hbegf | heparin-binding EGF-like growth factor | 0.046 | ||
| Thbd | thrombomodulin | 0.046 | ||
| Cdh1 | cadherin 1 | 0.045 | ||
| Phldb2 | pleckstrin homology-like domain, family B, member 2 | 0.045 | ||
| Gaa | glucosidase, alpha, acid | 0.045 | ||
| Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.042 | ||
| Kl | klotho | 0.042 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.041 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.040 | ||
| Fgf8 | fibroblast growth factor 8 | 0.039 | ||
| Aes | amino-terminal enhancer of split | 0.039 | ||
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.036 | ||
| Jag1 | jagged 1 | 0.036 | ||
| Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.035 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.035 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.035 | ||
| Ush1g | Usher syndrome 1G homolog (human) | 0.035 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.035 | ||
| Pdgfc | platelet-derived growth factor, C polypeptide | 0.034 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.033 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.033 | ||
| Ar | androgen receptor | 0.033 | ||
| Nrp1 | neuropilin 1 | 0.032 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.032 | ||
| Eng | endoglin | 0.032 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.031 | ||
| Aoc3 | amine oxidase, copper containing 3 | 0.031 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.030 | ||
| Dmkn | dermokine | 0.030 | ||
| Whrn | whirlin | 0.029 | ||
| Aplnr | apelin receptor | 0.026 | ||
| LOC100503041 | PDZ domain-containing protein 7-like | 0.024 | ||
| Dmd | dystrophin, muscular dystrophy | 0.024 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.024 | ||
| Apbb2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.024 | ||
| Gata6 | GATA binding protein 6 | 0.023 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.023 | ||
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.023 | ||
| Drd2 | dopamine receptor D2 | 0.022 | ||
| Hrh1 | histamine receptor H1 | 0.022 | ||
| Fxyd1 | FXYD domain-containing ion transport regulator 1 | 0.022 | ||
| Wwtr1 | WW domain containing transcription regulator 1 | 0.021 | ||
| Lama4 | laminin, alpha 4 | 0.021 | ||
| Vdr | vitamin D receptor | 0.020 | ||
| Pde8b | phosphodiesterase 8B | 0.020 | ||
| Gzmd | granzyme D | 0.020 | ||
| Mas1 | MAS1 oncogene | 0.020 | ||
| Sirpa | signal-regulatory protein alpha | 0.020 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.020 | ||
| Bmp6 | bone morphogenetic protein 6 | 0.019 | ||
| Lamb2 | laminin, beta 2 | 0.019 | ||
| Scrg1 | scrapie responsive gene 1 | 0.019 | ||
| Nov | nephroblastoma overexpressed gene | 0.018 | ||
| Ptafr | platelet-activating factor receptor | 0.018 | ||
| Aqp2 | aquaporin 2 | 0.018 | ||
| Acvr1 | activin A receptor, type 1 | 0.018 | ||
| Col8a1 | collagen, type VIII, alpha 1 | 0.018 | ||
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.018 | ||
| Crh | corticotropin releasing hormone | 0.018 | ||
| Gata4 | GATA binding protein 4 | 0.018 | ||
| Gja4 | gap junction protein, alpha 4 | 0.017 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.017 | ||
| Igfbp6 | insulin-like growth factor binding protein 6 | 0.017 | ||
| Ly6f | lymphocyte antigen 6 complex, locus F | 0.017 | ||
| Lmna | lamin A | 0.017 | ||
| Cldn5 | claudin 5 | 0.017 | ||
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.017 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.017 | ||
| Ntf3 | neurotrophin 3 | 0.016 | ||
| Figla | folliculogenesis specific basic helix-loop-helix | 0.016 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.016 | ||
| Myo7a | myosin VIIA | 0.016 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.016 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.016 | ||
| Gm13290 | predicted gene 13290 | 0.016 | ||
| Cyp11b2 | cytochrome P450, family 11, subfamily b, polypeptide 2 | 0.016 | ||
| Fli1 | Friend leukemia integration 1 | 0.016 | ||
| Snta1 | syntrophin, acidic 1 | 0.016 | ||
| Lama2 | laminin, alpha 2 | 0.016 | ||
| Nid1 | nidogen 1 | 0.015 | ||
| Clec14a | C-type lectin domain family 14, member a | 0.015 | ||
| Adra2b | adrenergic receptor, alpha 2b | 0.015 | ||
| Cbs | cystathionine beta-synthase | 0.015 | ||
| Mc2r | melanocortin 2 receptor | 0.015 | ||
| F3 | coagulation factor III | 0.015 | ||
| Nkx3-1 | NK-3 transcription factor, locus 1 (Drosophila) | 0.015 | ||
| Csda | cold shock domain protein A | 0.015 | ||
| Slco1a6 | solute carrier organic anion transporter family, member 1a6 | 0.015 | ||
| Myh10 | myosin, heavy polypeptide 10, non-muscle | 0.014 | ||
| Pomc | pro-opiomelanocortin-alpha | 0.014 | ||
| Elk3 | ELK3, member of ETS oncogene family | 0.014 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.014 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.014 | ||
| Lepr | leptin receptor | 0.014 | ||
| Tnxb | tenascin XB | 0.014 | ||
| Mal | myelin and lymphocyte protein, T-cell differentiation protein | 0.014 | ||
| Plau | plasminogen activator, urokinase | 0.014 | ||
| Entpd2 | ectonucleoside triphosphate diphosphohydrolase 2 | 0.014 | ||
| Slc18a1 | solute carrier family 18 (vesicular monoamine), member 1 | 0.014 | ||
| Aff1 | AF4/FMR2 family, member 1 | 0.014 | ||
| Sema3b | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.014 | ||
| Ptprm | protein tyrosine phosphatase, receptor type, M | 0.013 | ||
| Hsd3b4 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 | 0.013 | ||
| Ihh | Indian hedgehog | 0.013 | ||
| Rxra | retinoid X receptor alpha | 0.013 | ||
| Kit | kit oncogene | 0.013 | ||
| Nphs2 | nephrosis 2 homolog, podocin (human) | 0.013 | ||
| Abcc9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 0.013 | ||
| Smn1 | survival motor neuron 1 | 0.013 | ||
| Sox17 | SRY-box containing gene 17 | 0.013 | ||
| Fuz | fuzzy homolog (Drosophila) | 0.013 | ||
| Nfix | nuclear factor I/X | 0.013 | ||
| Fbln1 | fibulin 1 | 0.013 | ||
| Rdx | radixin | 0.013 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.013 | ||
| Cxcl12 | chemokine (C-X-C motif) ligand 12 | 0.013 | ||
| Wt1 | Wilms tumor 1 homolog | 0.013 | ||
| Ntn1 | netrin 1 | 0.013 | ||
| Rarb | retinoic acid receptor, beta | 0.013 | ||
| Col4a5 | collagen, type IV, alpha 5 | 0.013 | ||
| Pramel6 | preferentially expressed antigen in melanoma like 6 | 0.013 | ||
| Matn2 | matrilin 2 | 0.013 | ||
| Hoxd4 | homeobox D4 | 0.013 | ||
| Dkk3 | dickkopf homolog 3 (Xenopus laevis) | 0.012 | ||
| Miox | myo-inositol oxygenase | 0.012 | ||
| Oaz3 | ornithine decarboxylase antizyme 3 | 0.012 | ||
| Atp1a2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.012 | ||
| Cyr61 | cysteine rich protein 61 | 0.012 | ||
| Mbl1 | mannose-binding lectin (protein A) 1 | 0.012 | ||
| Pvr | poliovirus receptor | 0.012 | ||
| Hoxd10 | homeobox D10 | 0.012 | ||
| Egfr | epidermal growth factor receptor | 0.012 | ||
| Cnga3 | cyclic nucleotide gated channel alpha 3 | 0.012 | ||
| Slc6a12 | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 0.012 | ||
| Tspan9 | tetraspanin 9 | 0.012 | ||
| Plxnd1 | plexin D1 | 0.012 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.012 | ||
| Itpripl2 | inositol 1,4,5-triphosphate receptor interacting protein-like 2 | 0.012 | ||
| Fosl1 | fos-like antigen 1 | 0.012 | ||
| Ceacam12 | carcinoembryonic antigen-related cell adhesion molecule 12 | 0.012 | ||
| Stra6 | stimulated by retinoic acid gene 6 | 0.012 | ||
| Sox18 | SRY-box containing gene 18 | 0.012 | ||
| Slc23a2 | solute carrier family 23 (nucleobase transporters), member 2 | 0.012 | ||
| Vegfa | vascular endothelial growth factor A | 0.012 | Mouse | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.012 | ||
| Plvap | plasmalemma vesicle associated protein | 0.012 | ||
| Vwf | Von Willebrand factor homolog | 0.012 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.012 | ||
| Npr3 | natriuretic peptide receptor 3 | 0.012 | ||
| Cdh23 | cadherin 23 (otocadherin) | 0.012 | ||
| Gcnt2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme | 0.012 | ||
| Pcdh15 | protocadherin 15 | 0.012 | ||
| Fmo1 | flavin containing monooxygenase 1 | 0.012 | ||
| Srcrb4d | scavenger receptor cysteine rich domain containing, group B (4 domains) | 0.012 | ||
| Abcc2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.012 | ||
| Itga8 | integrin alpha 8 | 0.012 | ||
| Cldn2 | claudin 2 | 0.012 | ||
| Tmc1 | transmembrane channel-like gene family 1 | 0.012 | ||
| Sox7 | SRY-box containing gene 7 | 0.011 | ||
| Elf5 | E74-like factor 5 | 0.011 | ||
| Slc7a8 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 0.011 | ||
| Tm4sf1 | transmembrane 4 superfamily member 1 | 0.011 | ||
| Snx21 | sorting nexin family member 21 | 0.011 | ||
| Slc23a3 | solute carrier family 23 (nucleobase transporters), member 3 | 0.011 | ||
| Rhbdl3 | rhomboid, veinlet-like 3 (Drosophila) | 0.011 | ||
| Ccl17 | chemokine (C-C motif) ligand 17 | 0.011 | ||
| Htra1 | HtrA serine peptidase 1 | 0.011 | ||
| Mrc2 | mannose receptor, C type 2 | 0.011 | ||
| Lamb1 | laminin B1 | 0.011 | ||
| Gdf15 | growth differentiation factor 15 | 0.011 | ||
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.011 | ||
| Olfr94 | olfactory receptor 94 | 0.011 | ||
| Mgp | matrix Gla protein | 0.011 | ||
| Edn1 | endothelin 1 | 0.011 | ||
| Rasip1 | Ras interacting protein 1 | 0.011 | ||
| Pdgfa | platelet derived growth factor, alpha | 0.011 | Mouse | |
| Phlda3 | pleckstrin homology-like domain, family A, member 3 | 0.011 | ||
| Kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | 0.011 | ||
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.011 | ||
| Bdkrb2 | bradykinin receptor, beta 2 | 0.011 | ||
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.011 | ||
| Hoxd8 | homeobox D8 | 0.011 | ||
| Mapk13 | mitogen-activated protein kinase 13 | 0.011 | ||
| Coq9 | coenzyme Q9 homolog (yeast) | 0.011 | ||
| Sod3 | superoxide dismutase 3, extracellular | 0.011 | ||
| Htra3 | HtrA serine peptidase 3 | 0.011 | ||
| Prlr | prolactin receptor | 0.011 | ||
| Pls3 | plastin 3 (T-isoform) | 0.011 | ||
| Dkk2 | dickkopf homolog 2 (Xenopus laevis) | 0.011 | ||
| Plat | plasminogen activator, tissue | 0.011 | ||
| Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | 0.011 | ||
| Golt1a | golgi transport 1 homolog A (S. cerevisiae) | 0.011 | ||
| Smo | smoothened homolog (Drosophila) | 0.011 | ||
| Mkl2 | MKL/myocardin-like 2 | 0.011 | ||
| Cryab | crystallin, alpha B | 0.011 | ||
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.011 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.011 | ||
| Ear5 | eosinophil-associated, ribonuclease A family, member 5 | 0.011 | ||
| Irx3 | Iroquois related homeobox 3 (Drosophila) | 0.011 | ||
| Fkbp1b | FK506 binding protein 1b | 0.011 | ||
| Tnfsf9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.010 | ||
| Rasd1 | RAS, dexamethasone-induced 1 | 0.010 | ||
| Alpl | alkaline phosphatase, liver/bone/kidney | 0.010 | ||
| Acnat2 | acyl-coenzyme A amino acid N-acyltransferase 2 | 0.010 | ||
| Sdpr | serum deprivation response | 0.010 | ||
| Npy5r | neuropeptide Y receptor Y5 | 0.010 | ||
| Slc7a2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.010 | ||
| Sox4 | SRY-box containing gene 4 | 0.010 | ||
| Gdf1 | growth differentiation factor 1 | 0.010 | ||
| Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | 0.010 | ||
| Ocln | occludin | 0.010 | ||
| Fmo2 | flavin containing monooxygenase 2 | 0.010 | ||
| Ryr2 | ryanodine receptor 2, cardiac | 0.010 | ||
| Pcdh12 | protocadherin 12 | 0.010 | ||
| Itgam | integrin alpha M | 0.010 | ||
| Tmem204 | transmembrane protein 204 | 0.010 | ||
| Slc6a20b | solute carrier family 6 (neurotransmitter transporter), member 20B | 0.010 | ||
| Nfib | nuclear factor I/B | 0.010 | ||
| Anpep | alanyl (membrane) aminopeptidase | 0.010 | ||
| Aox1 | aldehyde oxidase 1 | 0.010 | ||
| Adm | adrenomedullin | 0.010 | ||
| Ccrl2 | chemokine (C-C motif) receptor-like 2 | 0.010 | ||
| Sufu | suppressor of fused homolog (Drosophila) | 0.010 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.010 |