IMP

Process View

Mus musculus

11 genes annotated in mouse

killing by host of symbiont cells

Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "killing by host of symbiont cells"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "killing by host of symbiont cells" (in gray)

Name	Description	Probability	Func Analog Organism
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.884
Ngp	neutrophilic granule protein	0.869	Mouse
Elane	elastase, neutrophil expressed	0.865
Mpo	myeloperoxidase	0.779
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.721
Gzmb	granzyme B	0.577	Mouse
Mmp8	matrix metallopeptidase 8	0.522
Cma1	chymase 1, mast cell	0.414	Mouse
Ctsg	cathepsin G	0.414
Prg2	proteoglycan 2, bone marrow	0.338
Ltf	lactotransferrin	0.315
Nfe2	nuclear factor, erythroid derived 2	0.226
Il18rap	interleukin 18 receptor accessory protein	0.214
Ccl4	chemokine (C-C motif) ligand 4	0.205
Gp1ba	glycoprotein 1b, alpha polypeptide	0.204
Slpi	secretory leukocyte peptidase inhibitor	0.200
Cpa3	carboxypeptidase A3, mast cell	0.188
Camp	cathelicidin antimicrobial peptide	0.188
Gfi1b	growth factor independent 1B	0.186
Prtn3	proteinase 3	0.182	Mouse
Ccl7	chemokine (C-C motif) ligand 7	0.180
Cxcl2	chemokine (C-X-C motif) ligand 2	0.175	Mouse
Cxcr2	chemokine (C-X-C motif) receptor 2	0.164
Trim10	tripartite motif-containing 10	0.152
Gzmc	granzyme C	0.151	Mouse
Rhag	Rhesus blood group-associated A glycoprotein	0.147
Slfn4	schlafen 4	0.144
Fasl	Fas ligand (TNF superfamily, member 6)	0.142
Gp9	glycoprotein 9 (platelet)	0.137
Xcl1	chemokine (C motif) ligand 1	0.129
Ptgir	prostaglandin I receptor (IP)	0.123
Ifng	interferon gamma	0.119
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.113
Il2rb	interleukin 2 receptor, beta chain	0.110
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.099
Gbp1	guanylate binding protein 1	0.097
Mcpt4	mast cell protease 4	0.091	Mouse
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.090
C5ar1	complement component 5a receptor 1	0.088
Ncr1	natural cytotoxicity triggering receptor 1	0.087
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.084
Il1b	interleukin 1 beta	0.082
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.081
Irg1	immunoresponsive gene 1	0.080
Gypa	glycophorin A	0.079
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.078
Ccl5	chemokine (C-C motif) ligand 5	0.077
Batf	basic leucine zipper transcription factor, ATF-like	0.075
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.075
Tal1	T-cell acute lymphocytic leukemia 1	0.073
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.073
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.072
Gzmf	granzyme F	0.071	Mouse
Ccl3	chemokine (C-C motif) ligand 3	0.069
Chi3l3	chitinase 3-like 3	0.066
Hemgn	hemogen	0.065
Itgb3	integrin beta 3	0.064
Mmp13	matrix metallopeptidase 13	0.058
Iigp1	interferon inducible GTPase 1	0.058
Il1rn	interleukin 1 receptor antagonist	0.056
Gpr97	G protein-coupled receptor 97	0.056
Gbp3	guanylate binding protein 3	0.055
Il6	interleukin 6	0.052
Rsad2	radical S-adenosyl methionine domain containing 2	0.052
Ubd	ubiquitin D	0.051
Niacr1	niacin receptor 1	0.051
Mcpt8	mast cell protease 8	0.050	Mouse
Gzmd	granzyme D	0.050	Mouse
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.050
LOC100504404	h-2 class II histocompatibility antigen, E-K alpha chain-like	0.050
Fpr1	formyl peptide receptor 1	0.050
Fcgr1	Fc receptor, IgG, high affinity I	0.049
Selp	selectin, platelet	0.048
Cd177	CD177 antigen	0.048
Il1r2	interleukin 1 receptor, type II	0.048
Ppbp	pro-platelet basic protein	0.046
Cma2	chymase 2, mast cell	0.045
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.044
Clec4e	C-type lectin domain family 4, member e	0.043
Prol1	proline rich, lacrimal 1	0.042
C2	complement component 2 (within H-2S)	0.041
Cst7	cystatin F (leukocystatin)	0.041
Il1rl1	interleukin 1 receptor-like 1	0.040
Sva	seminal vesicle antigen	0.040
H2-M9	histocompatibility 2, M region locus 9	0.040
Fpr2	formyl peptide receptor 2	0.038
Ear1	eosinophil-associated, ribonuclease A family, member 1	0.038
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.037
Mcpt2	mast cell protease 2	0.036	Mouse
Soat2	sterol O-acyltransferase 2	0.036
Mmp10	matrix metallopeptidase 10	0.036
Sftpa1	surfactant associated protein A1	0.035	Mouse
Ifitm6	interferon induced transmembrane protein 6	0.035
Ctsw	cathepsin W	0.034
Hc	hemolytic complement	0.033
Spna1	spectrin alpha 1	0.032
Prl7a1	prolactin family 7, subfamily a, member 1	0.032
Aqp7	aquaporin 7	0.032
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.032
Cd160	CD160 antigen	0.032
Fosl1	fos-like antigen 1	0.032
Ahsp	alpha hemoglobin stabilizing protein	0.032
Ccr1	chemokine (C-C motif) receptor 1	0.032
Gata1	GATA binding protein 1	0.032
Mmp2	matrix metallopeptidase 2	0.031
Cidec	cell death-inducing DFFA-like effector c	0.031
Ager	advanced glycosylation end product-specific receptor	0.031
Ccl22	chemokine (C-C motif) ligand 22	0.031
Nkg7	natural killer cell group 7 sequence	0.030
Gzme	granzyme E	0.030	Mouse
Ctse	cathepsin E	0.029
Ccrl2	chemokine (C-C motif) receptor-like 2	0.028
Ccl8	chemokine (C-C motif) ligand 8	0.028
Prl2b1	prolactin family 2, subfamily b, member 1	0.027
Mfap5	microfibrillar associated protein 5	0.027
Gdf15	growth differentiation factor 15	0.027
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.027
Slfn1	schlafen 1	0.026
Cxcl10	chemokine (C-X-C motif) ligand 10	0.026	Mouse
Sftpd	surfactant associated protein D	0.026	Mouse
Gp5	glycoprotein 5 (platelet)	0.026
Alox15	arachidonate 15-lipoxygenase	0.025
Clec4d	C-type lectin domain family 4, member d	0.025
Gfi1	growth factor independent 1	0.024
Ccl2	chemokine (C-C motif) ligand 2	0.024
Areg	amphiregulin	0.024
F10	coagulation factor X	0.024
Isg15	ISG15 ubiquitin-like modifier	0.023
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.023
Epb4.2	erythrocyte protein band 4.2	0.023
Ermap	erythroblast membrane-associated protein	0.023
Ltb4r1	leukotriene B4 receptor 1	0.023
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.022
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.022
Gzmg	granzyme G	0.022	Mouse
Atf3	activating transcription factor 3	0.022
Pgk2	phosphoglycerate kinase 2	0.021
Ms4a3	membrane-spanning 4-domains, subfamily A, member 3	0.021
Pcdh12	protocadherin 12	0.021
Stfa3	stefin A3	0.021
Ccl12	chemokine (C-C motif) ligand 12	0.021
Chi3l1	chitinase 3-like 1	0.021
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.020
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.020
Svs6	seminal vesicle secretory protein 6	0.020
Fcna	ficolin A	0.019
Fabp4	fatty acid binding protein 4, adipocyte	0.019
Ido1	indoleamine 2,3-dioxygenase 1	0.018
Sh2d2a	SH2 domain protein 2A	0.018
Rhd	Rh blood group, D antigen	0.018
1810019N24Rik	RIKEN cDNA 1810019N24 gene	0.018
Prl7d1	prolactin family 7, subfamily d, member 1	0.018
Wnt10b	wingless related MMTV integration site 10b	0.018
Car1	carbonic anhydrase 1	0.018
Cdcp1	CUB domain containing protein 1	0.018
Col13a1	collagen, type XIII, alpha 1	0.018
Cxcl1	chemokine (C-X-C motif) ligand 1	0.017
Cmklr1	chemokine-like receptor 1	0.017
Gpr35	G protein-coupled receptor 35	0.017
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.017
Igtp	interferon gamma induced GTPase	0.017
Col1a1	collagen, type I, alpha 1	0.016
Hdc	histidine decarboxylase	0.016
Prss2	protease, serine, 2	0.016
Cnn1	calponin 1	0.016
Folr2	folate receptor 2 (fetal)	0.016
Ifih1	interferon induced with helicase C domain 1	0.016
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.016
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.016
Tekt2	tektin 2	0.016
Ccl1	chemokine (C-C motif) ligand 1	0.016
Ccl11	chemokine (C-C motif) ligand 11	0.016
Ang2	angiogenin, ribonuclease A family, member 2	0.015
Rpl39l	ribosomal protein L39-like	0.015
Ctrl	chymotrypsin-like	0.015
Plunc	palate, lung, and nasal epithelium associated	0.015
Myf6	myogenic factor 6	0.015
Tg	thyroglobulin	0.014
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.014
Hp	haptoglobin	0.014
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.014
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.014
Retn	resistin	0.014
Chi3l4	chitinase 3-like 4	0.014
Epx	eosinophil peroxidase	0.013
Aoah	acyloxyacyl hydrolase	0.013
Prx	periaxin	0.013
Ltc4s	leukotriene C4 synthase	0.013
Gpr84	G protein-coupled receptor 84	0.013
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.013
Ccr5	chemokine (C-C motif) receptor 5	0.013
Tnni2	troponin I, skeletal, fast 2	0.013
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.013
Mgmt	O-6-methylguanine-DNA methyltransferase	0.013
Cxcl3	chemokine (C-X-C motif) ligand 3	0.013
Junb	Jun-B oncogene	0.012
Glrp1	glutamine repeat protein 1	0.012
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.012
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.012
Lag3	lymphocyte-activation gene 3	0.012
Ch25h	cholesterol 25-hydroxylase	0.012
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.012
Klk1b26	kallikrein 1-related petidase b26	0.012
Reg3g	regenerating islet-derived 3 gamma	0.012
Mx2	myxovirus (influenza virus) resistance 2	0.012
Il9r	interleukin 9 receptor	0.012
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.012
Mup4	major urinary protein 4	0.012
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.012
Kel	Kell blood group	0.012
F13a1	coagulation factor XIII, A1 subunit	0.012
Adipoq	adiponectin, C1Q and collagen domain containing	0.012
Dapk2	death-associated protein kinase 2	0.012
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.012
Il12rb1	interleukin 12 receptor, beta 1	0.012
Itgal	integrin alpha L	0.011
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.011
Ptges	prostaglandin E synthase	0.011
Adam8	a disintegrin and metallopeptidase domain 8	0.011
Omt2b	oocyte maturation, beta	0.011
Uts2r	urotensin 2 receptor	0.011
Aqp9	aquaporin 9	0.011
Il9	interleukin 9	0.011
Cxcl17	chemokine (C-X-C motif) ligand 17	0.011
Muc1	mucin 1, transmembrane	0.011
Fos	FBJ osteosarcoma oncogene	0.011
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
Sfrp4	secreted frizzled-related protein 4	0.011
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.011
Bmx	BMX non-receptor tyrosine kinase	0.011
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.010
Saa3	serum amyloid A 3	0.010
Tfpi2	tissue factor pathway inhibitor 2	0.010
Ceacam12	carcinoembryonic antigen-related cell adhesion molecule 12	0.010
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.010
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.010
Rfpl4	ret finger protein-like 4	0.010
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.010
Retnla	resistin like alpha	0.010
Cxcl9	chemokine (C-X-C motif) ligand 9	0.010	Mouse
Pi16	peptidase inhibitor 16	0.010
Naip1	NLR family, apoptosis inhibitory protein 1	0.010
Padi4	peptidyl arginine deiminase, type IV	0.010
Mucl1	mucin-like 1	0.010