IMP

Process View

Mus musculus

11 genes annotated in mouse

regulation of timing of cell differentiation

The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of timing of cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of timing of cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	0.999
Emx1	empty spiracles homolog 1 (Drosophila)	0.994
Sox2	SRY-box containing gene 2	0.979
Nog	noggin	0.699
Gli3	GLI-Kruppel family member GLI3	0.682
Neurod1	neurogenic differentiation 1	0.666
Hes1	hairy and enhancer of split 1 (Drosophila)	0.517
Tcf21	transcription factor 21	0.501
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.484
Emx2	empty spiracles homolog 2 (Drosophila)	0.435
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.409
Gdf5	growth differentiation factor 5	0.394	Mouse
Msx2	homeobox, msh-like 2	0.379
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.310
Gli2	GLI-Kruppel family member GLI2	0.287
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.272
Bmp7	bone morphogenetic protein 7	0.268	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.250
Eya1	eyes absent 1 homolog (Drosophila)	0.239
Gsc	goosecoid homeobox	0.227
Bmp4	bone morphogenetic protein 4	0.196
Tsc2	tuberous sclerosis 2	0.193
Prrx1	paired related homeobox 1	0.192
Arx	aristaless related homeobox	0.185
Bmp5	bone morphogenetic protein 5	0.184	Mouse
Msx1	homeobox, msh-like 1	0.175
Hoxd13	homeobox D13	0.174
Gbx2	gastrulation brain homeobox 2	0.161
Pax3	paired box gene 3	0.149
Fgf15	fibroblast growth factor 15	0.142
Tbx15	T-box 15	0.141
Fgfr2	fibroblast growth factor receptor 2	0.133
Zfpm2	zinc finger protein, multitype 2	0.120
Foxh1	forkhead box H1	0.117
Fgf9	fibroblast growth factor 9	0.114
Pofut1	protein O-fucosyltransferase 1	0.109
Alx4	aristaless-like homeobox 4	0.107
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.105
Ptf1a	pancreas specific transcription factor, 1a	0.102
Pbx1	pre B-cell leukemia transcription factor 1	0.101
Gli1	GLI-Kruppel family member GLI1	0.095
Chd7	chromodomain helicase DNA binding protein 7	0.088
Hes5	hairy and enhancer of split 5 (Drosophila)	0.088	Mouse
Zeb1	zinc finger E-box binding homeobox 1	0.088
Tecta	tectorin alpha	0.087
Hesx1	homeobox gene expressed in ES cells	0.086
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.084
Foxa2	forkhead box A2	0.081
Lhx3	LIM homeobox protein 3	0.079
Zic3	zinc finger protein of the cerebellum 3	0.078
Hoxa13	homeobox A13	0.078
Pax6	paired box gene 6	0.077
Wnt3a	wingless-related MMTV integration site 3A	0.075
Shc3	src homology 2 domain-containing transforming protein C3	0.075
Hand2	heart and neural crest derivatives expressed transcript 2	0.069
Neurog2	neurogenin 2	0.069
Bdnf	brain derived neurotrophic factor	0.067
Reln	reelin	0.067
Gdf1	growth differentiation factor 1	0.066
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.065
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.064
Nkx2-1	NK2 homeobox 1	0.063
Lhx5	LIM homeobox protein 5	0.063
Sox3	SRY-box containing gene 3	0.059
Per3	period homolog 3 (Drosophila)	0.059
Gja3	gap junction protein, alpha 3	0.056
Atoh7	atonal homolog 7 (Drosophila)	0.056
Pthlh	parathyroid hormone-like peptide	0.056
Isl1	ISL1 transcription factor, LIM/homeodomain	0.055
Foxg1	forkhead box G1	0.053
Dmrt1	doublesex and mab-3 related transcription factor 1	0.051
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.051
Pax2	paired box gene 2	0.050
Adra1a	adrenergic receptor, alpha 1a	0.049
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.047
Tdgf1	teratocarcinoma-derived growth factor 1	0.047
Edn3	endothelin 3	0.046
Pou3f4	POU domain, class 3, transcription factor 4	0.045
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.044
Wnt3	wingless-related MMTV integration site 3	0.043
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.043
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.042
Fgf14	fibroblast growth factor 14	0.042	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.041
Xpa	xeroderma pigmentosum, complementation group A	0.040
Guca2b	guanylate cyclase activator 2b (retina)	0.040
Sstr2	somatostatin receptor 2	0.039
Angpt1	angiopoietin 1	0.036
Hand1	heart and neural crest derivatives expressed transcript 1	0.036
Fgf18	fibroblast growth factor 18	0.036
Rb1	retinoblastoma 1	0.036
Pou3f3	POU domain, class 3, transcription factor 3	0.035
Tbx10	T-box 10	0.035
Neurog3	neurogenin 3	0.035
Apc	adenomatosis polyposis coli	0.034
Alx3	aristaless-like homeobox 3	0.034
Phox2b	paired-like homeobox 2b	0.034
Spry4	sprouty homolog 4 (Drosophila)	0.034
Btbd17	BTB (POZ) domain containing 17	0.034
Moxd2	monooxygenase, DBH-like 2	0.033
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.033
Tbx3	T-box 3	0.033
Gsbs	G substrate	0.032
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.032
Rint1	RAD50 interactor 1	0.031
Cntfr	ciliary neurotrophic factor receptor	0.030
Notch1	Notch gene homolog 1 (Drosophila)	0.029
Myod1	myogenic differentiation 1	0.029
Omp	olfactory marker protein	0.029
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.028
Lef1	lymphoid enhancer binding factor 1	0.028
Srcin1	SRC kinase signaling inhibitor 1	0.028
Gdf6	growth differentiation factor 6	0.028	Mouse
Nf2	neurofibromatosis 2	0.028
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.027
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.027
Fzd8	frizzled homolog 8 (Drosophila)	0.027
Axin2	axin2	0.027
Zfhx4	zinc finger homeodomain 4	0.026
Rlbp1	retinaldehyde binding protein 1	0.026
Pitx2	paired-like homeodomain transcription factor 2	0.025
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.025
Fgf4	fibroblast growth factor 4	0.025	Mouse
Foxc1	forkhead box C1	0.025
Podxl	podocalyxin-like	0.024
Foxf1a	forkhead box F1a	0.024
Nos2	nitric oxide synthase 2, inducible	0.024
Foxd1	forkhead box D1	0.024
Tcl1	T-cell lymphoma breakpoint 1	0.024
Dcx	doublecortin	0.023
Tbx2	T-box 2	0.023
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.023
Ctgf	connective tissue growth factor	0.023
Hist1h1t	histone cluster 1, H1t	0.023
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.023
Adrb1	adrenergic receptor, beta 1	0.022
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.022
Fzd7	frizzled homolog 7 (Drosophila)	0.022
Fgfbp1	fibroblast growth factor binding protein 1	0.022
Vipr2	vasoactive intestinal peptide receptor 2	0.022
Lrp2	low density lipoprotein receptor-related protein 2	0.022
Trp63	transformation related protein 63	0.021
Fgf10	fibroblast growth factor 10	0.021	Mouse
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.021
Defa-rs12	defensin, alpha, related sequence 12	0.021
Wnt5a	wingless-related MMTV integration site 5A	0.021
Gdf9	growth differentiation factor 9	0.020
Neurod4	neurogenic differentiation 4	0.020
Efna4	ephrin A4	0.020
Cer1	cerberus 1 homolog (Xenopus laevis)	0.020
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.019
Twist2	twist homolog 2 (Drosophila)	0.019
Pitx1	paired-like homeodomain transcription factor 1	0.019
Otx1	orthodenticle homolog 1 (Drosophila)	0.019
Acvr2b	activin receptor IIB	0.019
Smad6	MAD homolog 6 (Drosophila)	0.019
Fgf5	fibroblast growth factor 5	0.018	Mouse
Foxf2	forkhead box F2	0.018
Syt6	synaptotagmin VI	0.018
Onecut1	one cut domain, family member 1	0.018
Prrx2	paired related homeobox 2	0.018
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.018
Capn9	calpain 9	0.018
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.018
Hoxa9	homeobox A9	0.018
Insm1	insulinoma-associated 1	0.017
Foxb2	forkhead box B2	0.017
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.017
Gpc3	glypican 3	0.017
Rxrg	retinoid X receptor gamma	0.017
Uts2r	urotensin 2 receptor	0.017
Tcfap2b	transcription factor AP-2 beta	0.017
Pcdh12	protocadherin 12	0.016
Npr3	natriuretic peptide receptor 3	0.016
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.016
Dlx6	distal-less homeobox 6	0.016
Rln1	relaxin 1	0.016
Nf1	neurofibromatosis 1	0.016
Fut1	fucosyltransferase 1	0.016
Ager	advanced glycosylation end product-specific receptor	0.016
Adam4	a disintegrin and metallopeptidase domain 4	0.016
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.016
Ptk7	PTK7 protein tyrosine kinase 7	0.016
Nppc	natriuretic peptide type C	0.015
Tgfbr3	transforming growth factor, beta receptor III	0.015
Gas1	growth arrest specific 1	0.015
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.015
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.015
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.015
Foxd3	forkhead box D3	0.015
Hmx1	H6 homeobox 1	0.015
Glra1	glycine receptor, alpha 1 subunit	0.014
Bdkrb2	bradykinin receptor, beta 2	0.014
Pdx1	pancreatic and duodenal homeobox 1	0.014
Hoxb6	homeobox B6	0.014
Fgf13	fibroblast growth factor 13	0.014	Mouse
Wnt6	wingless-related MMTV integration site 6	0.014
Dll1	delta-like 1 (Drosophila)	0.013
Sox1	SRY-box containing gene 1	0.013
Gpr37	G protein-coupled receptor 37	0.013
Sel1l2	sel-1 suppressor of lin-12-like 2 (C. elegans)	0.013
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.013
Fabp9	fatty acid binding protein 9, testis	0.013
Rspo1	R-spondin homolog (Xenopus laevis)	0.013
Pln	phospholamban	0.013
Mgat3	mannoside acetylglucosaminyltransferase 3	0.013
Nptx2	neuronal pentraxin 2	0.013
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.013
Kcnk3	potassium channel, subfamily K, member 3	0.013
Gdf3	growth differentiation factor 3	0.013
Mark1	MAP/microtubule affinity-regulating kinase 1	0.013
Msi1	Musashi homolog 1(Drosophila)	0.013
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.012
Hoxd11	homeobox D11	0.012
Pten	phosphatase and tensin homolog	0.012
Gip	gastric inhibitory polypeptide	0.012
Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	0.012
Chrdl2	chordin-like 2	0.012
Epha3	Eph receptor A3	0.012
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.012
Pou5f1	POU domain, class 5, transcription factor 1	0.012
Sox17	SRY-box containing gene 17	0.012
Klf12	Kruppel-like factor 12	0.012
Ntn1	netrin 1	0.012
Ptch1	patched homolog 1	0.012
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.012
Cfc1	cripto, FRL-1, cryptic family 1	0.012
Dhh	desert hedgehog	0.012
Pgap1	post-GPI attachment to proteins 1	0.012
Zic1	zinc finger protein of the cerebellum 1	0.011
Sox9	SRY-box containing gene 9	0.011
Foxb1	forkhead box B1	0.011
H1foo	H1 histone family, member O, oocyte-specific	0.011
Musk	muscle, skeletal, receptor tyrosine kinase	0.011
Avpr2	arginine vasopressin receptor 2	0.011
Nodal	nodal	0.011
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.011
Dlx1	distal-less homeobox 1	0.011
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.011
Galr2	galanin receptor 2	0.011
Sh3pxd2a	SH3 and PX domains 2A	0.011
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.011
Nes	nestin	0.011
Prdm16	PR domain containing 16	0.011
Tead4	TEA domain family member 4	0.011
C1ql1	complement component 1, q subcomponent-like 1	0.011
Hes3	hairy and enhancer of split 3 (Drosophila)	0.011
Prox1	prospero-related homeobox 1	0.011
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.011
Mapk12	mitogen-activated protein kinase 12	0.010
Ghrl	ghrelin	0.010
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.010
Crx	cone-rod homeobox containing gene	0.010
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.010
Rgs6	regulator of G-protein signaling 6	0.010
Gata6	GATA binding protein 6	0.010
Edn2	endothelin 2	0.010
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.010	Mouse
Syt9	synaptotagmin IX	0.010
Tacr2	tachykinin receptor 2	0.010
Nmur1	neuromedin U receptor 1	0.010
Ifna2	interferon alpha 2	0.010