IMP

Process View

Rattus norvegicus

51 genes annotated in rat

regulation of endopeptidase activity

Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of endopeptidase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of endopeptidase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Jak1	Janus kinase 1	0.077
Fga	fibrinogen alpha chain	0.055
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.054
S100a8	S100 calcium binding protein A8	0.044	Human
S100a9	S100 calcium binding protein A9	0.036	Human
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.029
Ifitm3	interferon induced transmembrane protein 3	0.028
Arpc1b	actin related protein 2/3 complex, subunit 1B	0.027
Ccl2	chemokine (C-C motif) ligand 2	0.027
Hsph1	heat shock 105/110 protein 1	0.027
Alb	albumin	0.026
Proc	protein C	0.025
Tcrb	T-cell receptor beta chain	0.025
Fgfr1	Fibroblast growth factor receptor 1	0.024
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.024
Slc25a3	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3	0.024
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.023
Ptch1	patched homolog 1 (Drosophila)	0.023
Taok1	TAO kinase 1	0.023
Smad1	SMAD family member 1	0.023	Rat
Selp	selectin P	0.023
A2m	alpha-2-macroglobulin	0.022
Cd9	CD9 molecule	0.022
Agtr1a	angiotensin II receptor, type 1a	0.022
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.022
Rarres2	retinoic acid receptor responder (tazarotene induced) 2	0.022
Il7	interleukin 7	0.022
C1r	complement component 1, r subcomponent	0.022
S100a10	S100 calcium binding protein A10	0.022
Hpx	hemopexin	0.021
Ccl5	chemokine (C-C motif) ligand 5	0.021
Gja1	gap junction protein, alpha 1	0.020
Muc5ac	mucin 5AC, oligomeric mucus/gel-forming	0.019
Apoa2	apolipoprotein A-II	0.019
Ppt1	palmitoyl-protein thioesterase 1	0.019
Gzmk	granzyme K	0.019
Fgfr2	fibroblast growth factor receptor 2	0.019
Apoa1	apolipoprotein A-I	0.018
Hp	haptoglobin	0.018
Hspd1	heat shock protein 1 (chaperonin)	0.018	Human
Spink1	serine peptidase inhibitor, Kazal type 1	0.018	Mouse Rat
Smad2	SMAD family member 2	0.018	Rat
S100a6	S100 calcium binding protein A6	0.018
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.018
LOC293989	cytochrome P450-like	0.017
Orm1	orosomucoid 1	0.017
Cpb2	carboxypeptidase B2 (plasma)	0.017
LOC299282	Serine protease inhibitor	0.017	Rat
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.017
Creb1	cAMP responsive element binding protein 1	0.017
Cd3g	CD3 molecule, gamma	0.017
Myo1b	myosin Ib	0.017
Ahsg	alpha-2-HS-glycoprotein	0.017
Gadd45a	growth arrest and DNA-damage-inducible, alpha	0.017
Icos	inducible T-cell co-stimulator	0.017
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.017
Gjb3	gap junction protein, beta 3	0.017
Ccnd3	cyclin D3	0.016
Wdr26	WD repeat domain 26	0.016
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.016
Cp	ceruloplasmin	0.016
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.016
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.016
Mt1a	metallothionein 1a	0.016
C1s	complement component 1, s subcomponent	0.016
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.016
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.016
Impdh2	IMP (inosine monophosphate) dehydrogenase 2	0.016
Lgals3	lectin, galactoside-binding, soluble, 3	0.016
Atf3	activating transcription factor 3	0.016
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.016
LOC691259	hypothetical protein LOC691259	0.016
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.016
Il2rb	interleukin 2 receptor, beta	0.015
Serpina1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.015
Marcks	myristoylated alanine rich protein kinase C substrate	0.015
Gbp2	guanylate binding protein 2	0.015
Adam10	ADAM metallopeptidase domain 10	0.015
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.015
Acvr1	activin A receptor, type I	0.015
Mprip	myosin phosphatase Rho interacting protein	0.015
Marcksl1	MARCKS-like 1	0.015
Socs3	suppressor of cytokine signaling 3	0.015
Cdk4	cyclin-dependent kinase 4	0.015
Kng2	kininogen 2	0.015
Apoa5	apolipoprotein A-V	0.015
Fabp1	fatty acid binding protein 1, liver	0.015	Human
Ptprh	protein tyrosine phosphatase, receptor type, H	0.015
Akr1b7	aldo-keto reductase family 1, member B7	0.015
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.015
Bcl2l1	Bcl2-like 1	0.014
Cd40lg	CD40 ligand	0.014	Rat
Ece1	endothelin converting enzyme 1	0.014
Esr1	estrogen receptor 1	0.014
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.014
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.014
Cd53	Cd53 molecule	0.014
Cd44	Cd44 molecule	0.014	Human
Rps5	ribosomal protein S5	0.014
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.014
Pgk1	phosphoglycerate kinase 1	0.014
Matk	megakaryocyte-associated tyrosine kinase	0.014
Hexa	hexosaminidase A	0.014
Anxa4	annexin A4	0.014
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.014
Dlg1	discs, large homolog 1 (Drosophila)	0.014
RT1-N3	RT1 class Ib, locus N3	0.014
Adm	adrenomedullin	0.014
Cd37	CD37 molecule	0.013
Accn5	amiloride-sensitive cation channel 5, intestinal	0.013
Utrn	utrophin	0.013
Hist1h1a	histone cluster 1, H1a	0.013
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.013
Sp1	Sp1 transcription factor	0.013
Lamc1	laminin, gamma 1	0.013
Reg3a	regenerating islet-derived 3 alpha	0.013
Rgs3	regulator of G-protein signaling 3	0.013
Jak2	Janus kinase 2	0.013	Mouse
Cd3e	CD3 molecule, epsilon	0.013
C4bpb	complement component 4 binding protein, beta	0.013
Rps10	ribosomal protein S10	0.013
Nmur1	neuromedin U receptor 1	0.013
LOC100361261	rCG23560-like	0.013
Ppap2a	phosphatidic acid phosphatase type 2A	0.013
A3galt2	alpha 1,3-galactosyltransferase 2	0.013
Rnf4	ring finger protein 4	0.013
Ssrp1	structure specific recognition protein 1	0.013
Ubtf	upstream binding transcription factor, RNA polymerase I	0.013
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.013
Ripk3	receptor-interacting serine-threonine kinase 3	0.013
Pzp	pregnancy-zone protein	0.013	Rat
Gnrhr	gonadotropin releasing hormone receptor	0.013
Cfi	complement factor I	0.013
Vamp2	vesicle-associated membrane protein 2	0.013
Vip	vasoactive intestinal peptide	0.012
Apoe	apolipoprotein E	0.012
Nmnat2	nicotinamide nucleotide adenylyltransferase 2	0.012
Il13ra1	interleukin 13 receptor, alpha 1	0.012
Tgfb1	transforming growth factor, beta 1	0.012
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.012
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.012
Aco2	aconitase 2, mitochondrial	0.012
Itgad	integrin, alpha D	0.012
Dnaja4	DnaJ (Hsp40) homolog, subfamily A, member 4	0.012
Gulo	gulonolactone (L-) oxidase	0.012
Rap1b	RAP1B, member of RAS oncogene family	0.012
LOC100362824	caveolin 2-like	0.012
Serpina3m	serine (or cysteine) proteinase inhibitor, clade A, member 3M	0.012	Rat
Rab13	RAB13, member RAS oncogene family	0.012
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.012
Smgc	submandibular gland protein C	0.012
Eef2	eukaryotic translation elongation factor 2	0.012
Edn1	endothelin 1	0.012
Mgp	matrix Gla protein	0.012
Serpina4	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	0.012	Rat
Dcaf17	DDB1 and CUL4 associated factor 17	0.012
Max	MYC associated factor X	0.012
Txnrd1	thioredoxin reductase 1	0.012
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.012
Sulf1	sulfatase 1	0.012
Csnk1g3	casein kinase 1, gamma 3	0.012
Stfa2l3	stefin A2-like 3	0.012
Stat3	signal transducer and activator of transcription 3	0.012
Oprd1	opioid receptor, delta 1	0.012
Prr5l	proline rich 5 like	0.012
Itm2c	integral membrane protein 2C	0.012
C1qbp	complement component 1, q subcomponent binding protein	0.012
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.012	Rat
Sell	selectin L	0.012
RGD1565859	RGD1565859	0.012
Pik3r3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.012
Il1b	interleukin 1 beta	0.012
Ckmt1	creatine kinase, mitochondrial 1	0.012
Pdhx	pyruvate dehydrogenase complex, component X	0.012
Pfn1	profilin 1	0.012
Il8rb	interleukin 8 receptor, beta	0.012
Dctn4	dynactin 4	0.012
Sfrs2	splicing factor, arginine/serine-rich 2	0.012
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.012
Guca1b	guanylate cyclase activator 1B	0.012
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.012
Prok2	prokineticin 2	0.012
Slit3	slit homolog 3 (Drosophila)	0.012
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.012
Errfi1	ERBB receptor feedback inhibitor 1	0.011
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.011
Baat	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.011
Mpeg1	macrophage expressed 1	0.011
Sirpa	signal-regulatory protein alpha	0.011
Tmed3	transmembrane emp24 protein transport domain containing 3	0.011
Smad7	SMAD family member 7	0.011	Rat
Xpo1	exportin 1, CRM1 homolog (yeast)	0.011
Gltscr2	glioma tumor suppressor candidate region gene 2	0.011
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.011
Atp5b	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.011
Nmur2	neuromedin U receptor 2	0.011
Ptgs2	prostaglandin-endoperoxide synthase 2	0.011
Lbp	lipopolysaccharide binding protein	0.011
Fgg	fibrinogen gamma chain	0.011
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.011
Pnliprp1	pancreatic lipase-related protein 1	0.011
Slfn2	schlafen 2	0.011
Lipogenin	Lipogenin	0.011
Mfhas1	malignant fibrous histiocytoma amplified sequence 1	0.011
Nras	neuroblastoma ras oncogene	0.011
Kpnb1	karyopherin (importin) beta 1	0.011
Ptgs1	prostaglandin-endoperoxide synthase 1	0.011
Il1r1	interleukin 1 receptor, type I	0.011
Serpina7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.011	Rat
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.011
Cct7	chaperonin containing Tcp1, subunit 7 (eta)	0.011
Spp2	secreted phosphoprotein 2	0.011
Ubqln1	ubiquilin 1	0.011
Pnliprp2	pancreatic lipase-related protein 2	0.011
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.011
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.011
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.011	Rat Fly
Litaf	lipopolysaccharide-induced TNF factor	0.011
Adrb2	adrenergic, beta-2-, receptor, surface	0.011
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.011
Sycn	syncollin	0.011
Cd80	Cd80 molecule	0.011
LOC100360587	hypothetical protein LOC100360587	0.011
C4bpa	complement component 4 binding protein, alpha	0.011
Psd4	pleckstrin and Sec7 domain containing 4	0.011
Smad4	SMAD family member 4	0.011	Rat
Plg	plasminogen	0.011
Hsp90b1	heat shock protein 90, beta, member 1	0.011
Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.011
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.011
Nos3	nitric oxide synthase 3, endothelial cell	0.011
Pecam1	platelet/endothelial cell adhesion molecule 1	0.011
Ddr1	discoidin domain receptor tyrosine kinase 1	0.011
A1i3	alpha-1-inhibitor III	0.011
Hlx	H2.0-like homeobox	0.011
Phkg1	phosphorylase kinase, gamma 1	0.011
Btc	betacellulin	0.011
Ubb	ubiquitin B	0.011
Aqp9	aquaporin 9	0.011
Cxcr7	chemokine (C-X-C motif) receptor 7	0.011
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.011
Fgl2	fibrinogen-like 2	0.011
Hbe2	hemoglobin, epsilon 2	0.011
F2	coagulation factor II (thrombin)	0.011
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.011	Rat
Asgr1	asialoglycoprotein receptor 1	0.011
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.011
Cpxm2	carboxypeptidase X (M14 family), member 2	0.011
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.011
Galnt1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	0.011
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.011
Msx2	msh homeobox 2	0.011
Hspb1	heat shock protein 1	0.011
Idh3B	isocitrate dehydrogenase 3 (NAD+) beta	0.011
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.011	Human Mouse Rat
Glra3	glycine receptor, alpha 3	0.011
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.011	Rat
Ppard	peroxisome proliferator-activated receptor delta	0.011
Homer3	homer homolog 3 (Drosophila)	0.011
Tbxa2r	thromboxane A2 receptor	0.011
Ctdspl	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	0.011
Adam17	ADAM metallopeptidase domain 17	0.011
Ppic	peptidylprolyl isomerase C	0.011
Pdgfb	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.011
Sphk1	sphingosine kinase 1	0.011
Cttnbp2nl	CTTNBP2 N-terminal like	0.010
Dlst	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	0.010
Cd2ap	CD2-associated protein	0.010
Pcdhgc3	protocadherin gamma subfamily C, 3	0.010
Commd2	COMM domain containing 2	0.010
Cd52	CD52 antigen	0.010
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.010
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.010
Cdc42bpb	CDC42 binding protein kinase beta (DMPK-like)	0.010
Spink3	serine peptidase inhibitor, Kazal type 3	0.010
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.010
Uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.010
Nrp2	neuropilin 2	0.010
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.010
Itpka	inositol 1,4,5-trisphosphate 3-kinase A	0.010
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.010
Pkn2	protein kinase N2	0.010
Srgn	serglycin	0.010
Vcan	versican	0.010
Vamp3	vesicle-associated membrane protein 3	0.010
Psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.010
Dynll1	dynein light chain LC8-type 1	0.010
C4b	complement component 4B (Chido blood group)	0.010	Rat
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.010
Bdkrb2	bradykinin receptor B2	0.010
Krt34	keratin 34	0.010
Igh-6	immunoglobulin heavy chain 6	0.010
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.010
Hpcal1	hippocalcin-like 1	0.010
LOC100361569	mage-d3-like	0.010
Adrb1	adrenergic, beta-1-, receptor	0.010
Chchd2	coiled-coil-helix-coiled-coil-helix domain containing 2	0.010
Ttr	transthyretin	0.010
Sval1	seminal vesicle antigen-like 1	0.010
Hspa1l	heat shock protein 1-like	0.010
Tff2	trefoil factor 2	0.010
Tgfb3	transforming growth factor, beta 3	0.010
B2m	beta-2 microglobulin	0.010
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.010
Vcp	valosin-containing protein	0.010	Mouse
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.010
Gc	group specific component	0.010
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.010
Hadhb	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	0.010
Aldoa	aldolase A, fructose-bisphosphate	0.010
Lass5	LAG1 homolog, ceramide synthase 5	0.010
Hemgn	hemogen	0.010
LOC308990	hypothetical protein LOC308990	0.010
Mat1a	methionine adenosyltransferase I, alpha	0.010
Cd83	CD83 molecule	0.010
Gsn	gelsolin	0.010
Chga	chromogranin A	0.010
Ctsa	cathepsin A	0.010
Fgb	fibrinogen beta chain	0.010
H3f3b	H3 histone, family 3B	0.010
Nat1	N-acetyltransferase 1	0.010
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.010
Phlda1	pleckstrin homology-like domain, family A, member 1	0.010
Vsnl1	visinin-like 1	0.010
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.010
Uox	urate oxidase	0.010
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.010
Eif1	eukaryotic translation initiation factor 1	0.010
Cugbp2	CUG triplet repeat, RNA binding protein 2	0.010