The network for 'organic hydroxy compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organic hydroxy compound metabolic process

The chemical reactions and pathways involving organic hydroxy compound.

Homo sapiens
Name Description Probability Func Analog Organism
HNF4A hepatocyte nuclear factor 4, alpha 0.998
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.995
FGFR2 fibroblast growth factor receptor 2 0.987
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.986
SC4MOL sterol-C4-methyl oxidase-like 0.985
SREBF2 sterol regulatory element binding transcription factor 2 0.972
FGF1 fibroblast growth factor 1 (acidic) 0.964
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.960
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.926
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.922
DHCR7 7-dehydrocholesterol reductase 0.914
APOE apolipoprotein E 0.903
FDPS farnesyl diphosphate synthase 0.896
APOA1 apolipoprotein A-I 0.882
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.876
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.871
CFLAR CASP8 and FADD-like apoptosis regulator 0.859
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.855
INSIG1 insulin induced gene 1 0.851
DHCR24 24-dehydrocholesterol reductase 0.837
NCOR2 nuclear receptor corepressor 2 0.820
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.819
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.817
SH3BP2 SH3-domain binding protein 2 0.808
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.806
SQLE squalene epoxidase 0.804
IDI1 isopentenyl-diphosphate delta isomerase 1 0.791
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.787
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.782
BCL3 B-cell CLL/lymphoma 3 0.778
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.771
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.760
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.748
IL1R1 interleukin 1 receptor, type I 0.717
SCP2 sterol carrier protein 2 0.715
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.713
TTR transthyretin 0.689
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.680
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.670
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.661
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 0.660
C14orf1 chromosome 14 open reading frame 1 0.655
MAPT microtubule-associated protein tau 0.654
MASP2 mannan-binding lectin serine peptidase 2 0.653
FGFR1 fibroblast growth factor receptor 1 0.649
MAP2K4 mitogen-activated protein kinase kinase 4 0.638
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.637
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.636
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 0.635
FGA fibrinogen alpha chain 0.625
SMAD2 SMAD family member 2 0.616
GRB7 growth factor receptor-bound protein 7 0.615
RHOA ras homolog gene family, member A 0.609
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.608
MAT1A methionine adenosyltransferase I, alpha 0.607
TALDO1 transaldolase 1 0.591
NCF1 neutrophil cytosolic factor 1 0.586
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.563
ARHGAP1 Rho GTPase activating protein 1 0.563
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.558
ZNF746 zinc finger protein 746 0.556
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.548
PDZD11 PDZ domain containing 11 0.543
SMAD3 SMAD family member 3 0.534
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.524
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.523
ACAT2 acetyl-CoA acetyltransferase 2 0.522
ZFYVE9 zinc finger, FYVE domain containing 9 0.517
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.493
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.489
SH3KBP1 SH3-domain kinase binding protein 1 0.479
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.477
FGB fibrinogen beta chain 0.471
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.466
GLYAT glycine-N-acyltransferase 0.458
CRP C-reactive protein, pentraxin-related 0.455
TAL1 T-cell acute lymphocytic leukemia 1 0.450
ACAA2 acetyl-CoA acyltransferase 2 0.446
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.441
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.439
KNG1 kininogen 1 0.436
WDYHV1 WDYHV motif containing 1 0.434
BMPR1A bone morphogenetic protein receptor, type IA 0.427
CHUK conserved helix-loop-helix ubiquitous kinase 0.419
RXRA retinoid X receptor, alpha 0.409
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.408
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.403
FAS Fas (TNF receptor superfamily, member 6) 0.400
NOXA1 NADPH oxidase activator 1 0.399
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.393
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.381
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.373
TKT transketolase 0.372
C8A complement component 8, alpha polypeptide 0.372
A2M alpha-2-macroglobulin 0.368
SKI v-ski sarcoma viral oncogene homolog (avian) 0.366
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.366
LAMP1 lysosomal-associated membrane protein 1 0.365
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.364
PRDX1 peroxiredoxin 1 0.357
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
hum-6 Protein HUM-6 0.082
cat-2 Protein CAT-2 0.079
cat-1 Protein CAT-1 0.070
plc-1 Protein PLC-1 0.069
ace-1 Protein ACE-1 0.068
ace-2 Protein ACE-2 0.064
acs-14 Protein ACS-14 0.054
C44C1.5 Protein C44C1.5 0.047
T04F8.2 Protein T04F8.2 0.046
pssy-1 Protein PSSY-1 0.045
C46H11.2 Protein C46H11.2 0.041
sgn-1 Protein SGN-1 0.040
alh-12 Protein ALH-12 0.038
K07E3.4 Protein K07E3.4 0.037
dhs-7 Protein DHS-7 0.034
C39D10.7 Protein C39D10.7 0.033
F46H5.7 Protein F46H5.7 0.030
CELE_C29F7.2 Protein C29F7.2 0.030
ceh-13 Protein CEH-13 0.029
fln-2 Protein FLN-2 0.029
hlh-1 Protein HLH-1 0.029
CELE_K09H11.1 Protein K09H11.1 0.028
H41C03.3 Protein H41C03.3 0.028
aak-2 Protein AAK-2 0.028
ttr-35 Protein TTR-35 0.027
F59A3.4 Protein F59A3.4 0.027
osm-11 Protein OSM-11 0.025
daf-2 Protein DAF-2 0.025
ugt-23 Protein UGT-23 0.025
dhs-16 Protein DHS-16 0.025
egl-30 Protein EGL-30 0.025
dnj-7 Protein DNJ-7 0.023
cyp-35A2 Protein CYP-35A2 0.023
bar-1 Protein BAR-1 0.022
T16G12.1 Protein T16G12.1 0.022
goa-1 Protein GOA-1 0.022
R12C12.1 Protein R12C12.1 0.021
ace-4 Protein ACE-4 0.021
clh-1 Protein CLH-1 0.021
pes-9 Protein PES-9 0.021
CELE_C01G10.9 Protein C01G10.9 0.021
daf-3 Protein DAF-3 0.021
F13E6.5 Protein F13E6.5 0.020
elo-5 Protein ELO-5 0.020
C34C12.6 Protein C34C12.6 0.020
pho-1 Protein PHO-1 0.020
mrp-1 Protein MRP-1 0.020
sur-5 Protein SUR-5 0.020
ace-3 Protein ACE-3 0.020
gspd-1 Protein GSPD-1 0.019
cyp-35A3 Protein CYP-35A3 0.019
C13C4.5 Protein C13C4.5 0.019
egl-15 Protein EGL-15 0.019
acp-6 Protein ACP-6 0.019
sem-5 Protein SEM-5 0.019
cam-1 Protein CAM-1 0.019
vav-1 Protein VAV-1 0.019
sto-5 Protein STO-5 0.018
unc-24 Protein UNC-24 0.018
T28H10.2 Protein T28H10.2 0.018
CELE_C09G9.1 Protein C09G9.1 0.018
F25B5.3 Protein F25B5.3 0.018
mig-23 Protein MIG-23 0.018
T20B12.7 Protein T20B12.7 0.018
mig-17 Protein MIG-17 0.017
vab-3 Protein VAB-3 0.017
W01C8.5 Protein W01C8.5 0.017
chat-1 Protein CHAT-1 0.017
ser-3 Protein SER-3 0.017
ZC247.1 Protein ZC247.1 0.017
F14D12.1 Protein F14D12.1 0.017
pkg-1 Protein PKG-1 0.016
nep-12 Protein NEP-12 0.016
C18H9.6 Protein C18H9.6 0.016
acox-1 Protein ACOX-1 0.016
mig-2 Protein MIG-2 0.016
gob-1 Protein GOB-1 0.016
Y48E1B.3 Protein Y48E1B.3 0.015
lev-8 Protein LEV-8 0.015
F35D2.2 Protein F35D2.2 0.015
inx-1 Protein INX-1 0.015
C11H1.9 Protein C11H1.9 0.015
F52C12.4 Protein F52C12.4 0.015
H22K11.2 Protein H22K11.2 0.015
bas-1 Protein BAS-1 0.015
psd-1 Protein PSD-1 0.015
poml-4 Protein POML-4 0.015
F52D10.2 Protein F52D10.2 0.015
npr-28 Protein NPR-28 0.015
hsp-12.1 Protein HSP-12.1 0.015
prl-1 Protein PRL-1 0.014
fkh-2 Protein FKH-2 0.014
nhr-80 Protein NHR-80 0.014
gras-1 Protein GRAS-1 0.014
pho-13 Protein PHO-13 0.014
pitp-1 Protein PITP-1 0.014
vab-1 Protein VAB-1 0.014
cyp-35C1 Protein CYP-35C1 0.014
cTel55X.1 Protein cTel55X.1 0.014
nac-3 Protein NAC-3 0.014
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cyp1a cytochrome P450, family 1, subfamily A 0.082
bactin2 bactin2 0.078
apoa4 apolipoprotein A-IV 0.071
gfra1b gdnf family receptor alpha 1b 0.051
gstt1a glutathione S-transferase theta 1a 0.050
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.041
rag1 recombination activating gene 1 0.040
mao monoamine oxidase 0.039
slc24a5 solute carrier family 24, member 5 0.038
ildr1b immunoglobulin-like domain containing receptor 1b 0.035
tbx2b T-box 2b 0.035
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.034
hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 0.033
stc1l stanniocalcin 1, like 0.032
tyrp1b tyrosinase-related protein 1b 0.032
crh corticotropin releasing hormone 0.032
mitfa microphthalmia-associated transcription factor a 0.029
gata5 GATA-binding protein 5 0.028
pgrmc1 progesterone receptor membrane component 1 0.027
dlx5a distal-less homeobox gene 5a 0.026
pou1f1 POU domain, class 1, transcription factor 1 0.025
cdx1b caudal type homeobox 1 b 0.025
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.024
fshb follicle stimulating hormone, beta polypeptide 0.023
acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.023
apobl apolipoprotein B, like 0.022
pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.022
zgc:162119 zgc:162119 0.022
dct dopachrome tautomerase 0.021
pitx3 paired-like homeodomain transcription factor 3 0.021
tyr tyrosinase 0.021
szl sizzled 0.021
cry5 cryptochrome 5 0.020
ddc dopa decarboxylase 0.020
cat catalase 0.020
tshb thyroid stimulating hormone, beta subunit 0.020
otpa orthopedia homolog a 0.020
pla2g12b phospholipase A2, group XIIB 0.020
shha sonic hedgehog a 0.019
bmp2a bone morphogenetic protein 2a 0.019
bmp2b bone morphogenetic protein 2b 0.019
cdh23 cadherin-like 23 0.019
grem2 gremlin 2, cysteine knot superfamily 0.018
si:ch211-215l11.5 si:ch211-215l11.5 0.017
pparg peroxisome proliferator activated receptor gamma 0.017
nme4 non-metastatic cells 4, protein expressed in 0.016
tmem86b transmembrane protein 86B 0.016
dbh dopamine beta hydroxylase 0.016
rgrb retinal G protein coupled receptor b 0.016
igf3 insulin-like growth factor 3 0.016
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.016
mmp9 matrix metalloproteinase 9 0.016
drd2a dopamine receptor D2a 0.015
gata4 GATA-binding protein 4 0.015
acadl acyl-Coenzyme A dehydrogenase, long chain 0.015
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.015
cldng claudin g 0.015
efnb3b ephrin B3b 0.015
notch1a notch homolog 1a 0.014
slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.014
grn2 granulin 2 0.014
fabp10a fatty acid binding protein 10a, liver basic 0.014
nr1i2 nuclear receptor subfamily 1, group I, member 2 0.014
ptgesl prostaglandin E synthase 2-like 0.014
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.014
apob apolipoprotein B 0.014
vdra vitamin D receptor a 0.014
irx5a iroquois homeobox protein 5a 0.013
lhb luteinizing hormone, beta polypeptide 0.013
dlc deltaC 0.013
aldocb aldolase C, fructose-bisphosphate, b 0.013
sycp3l synaptonemal complex protein 3 like 0.013
cpt1b carnitine palmitoyltransferase 1B (muscle) 0.013
bcl2 B-cell leukemia/lymphoma 2 0.013
sc:d411 sc:d411 0.013
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.013
tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) 0.013
gpx4a glutathione peroxidase 4a 0.013
ephb3a eph receptor B3a 0.013
bmp1a bone morphogenetic protein 1a 0.013
lhcgr luteinizing hormone/choriogonadotropin receptor 0.013
pitx1 paired-like homeodomain transcription factor 1 0.013
myo6b myosin VIb 0.013
zgc:161979 zgc:161979 0.012
try trypsin 0.012
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.012
slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.012
sox9b SRY-box containing gene 9b 0.012
fgf3 fibroblast growth factor 3 0.012
si:dkey-24g18.2 si:dkey-24g18.2 0.012
si:ch211-93f2.1 si:ch211-93f2.1 0.012
fgfr1a fibroblast growth factor receptor 1a 0.012
idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.012
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.011
acadm acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain 0.011
wnt5b wingless-type MMTV integration site family, member 5b 0.011
adh5 alcohol dehydrogenase 5 0.011
rtn4rl2a reticulon 4 receptor-like 2 a 0.011
tac1 tachykinin 1 0.011
hoxb1b homeo box B1b 0.011
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
PGRP-LC Peptidoglycan recognition protein LC 0.968
ttk tramtrack 0.948
Rac1 CG2248 gene product from transcript CG2248-RA 0.939
proPO-A1 prophenol oxidase A1 0.856
FucT6 alpha1,6-fucosyltransferase 0.817
Rac2 CG8556 gene product from transcript CG8556-RA 0.803
CG14815 CG14815 gene product from transcript CG14815-RA 0.800
Spn28D Serpin 28D 0.721
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.700
Ras85D Ras oncogene at 85D 0.698
CG6283 CG6283 gene product from transcript CG6283-RA 0.662
Ddc Dopa decarboxylase 0.642
Flo-2 flotillin 2 0.634
alpha-Est7 alpha-Esterase-7 0.611
Rel Relish 0.588
Ephrin CG1862 gene product from transcript CG1862-RA 0.576
SPE Spatzle-Processing Enzyme 0.550
Lsp1alpha Larval serum protein 1 alpha 0.530
Exn Ephexin 0.498
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.463
loco locomotion defects 0.451
Eb1 CG3265 gene product from transcript CG3265-RF 0.447
CG12428 CG12428 gene product from transcript CG12428-RB 0.446
rhea CG6831 gene product from transcript CG6831-RA 0.433
Sp7 Serine protease 7 0.421
ush u-shaped 0.415
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.401
ATP7 CG1886 gene product from transcript CG1886-RB 0.398
alpha-Man-IIb CG4606 gene product from transcript CG4606-RA 0.398
CG17597 CG17597 gene product from transcript CG17597-RA 0.383
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.376
CG3880 CG3880 gene product from transcript CG3880-RA 0.375
fon fondue 0.371
Spn1 Serine protease inhibitor 1 0.363
Lsp1beta Larval serum protein 1 beta 0.360
Pink1 PTEN-induced putative kinase 1 0.360
dib disembodied 0.327
Yp3 Yolk protein 3 0.323
CG2107 CG2107 gene product from transcript CG2107-RA 0.322
dia diaphanous 0.319
milt milton 0.307
NetB Netrin-B 0.297
nec necrotic 0.296
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.290
Mgat1 UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I 0.283
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.281
ptc patched 0.277
eve even skipped 0.277
RhoBTB CG5701 gene product from transcript CG5701-RA 0.273
CG11874 CG11874 gene product from transcript CG11874-RA 0.271
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.270
vav CG7893 gene product from transcript CG7893-RB 0.259
Mad Mothers against dpp 0.256
repo reversed polarity 0.255
CG10550 CG10550 gene product from transcript CG10550-RB 0.252
Cyp28a5 CG8864 gene product from transcript CG8864-RA 0.250
Tbh Tyramine beta hydroxylase 0.249
CG7830 CG7830 gene product from transcript CG7830-RA 0.246
Treh Trehalase 0.246
pie pineapple eye 0.245
Egfr Epidermal growth factor receptor 0.240
CG2064 CG2064 gene product from transcript CG2064-RA 0.236
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.235
alpha-Man-I alpha Mannosidase I 0.235
Prat2 Phosphoribosylamidotransferase 2 0.224
Tpi Triose phosphate isomerase 0.217
ome omega 0.215
CG2254 CG2254 gene product from transcript CG2254-RA 0.215
myoglianin CG1838 gene product from transcript CG1838-RD 0.213
CG11151 CG11151 gene product from transcript CG11151-RA 0.212
Cyp9f2 CG11466 gene product from transcript CG11466-RB 0.207
Hml Hemolectin 0.207
Cyp6a13 CG2397 gene product from transcript CG2397-RA 0.207
sim single-minded 0.204
CG42377 CG42377 gene product from transcript CG42377-RA 0.204
krz kurtz 0.204
gcm glial cells missing 0.202
CG3415 CG3415 gene product from transcript CG3415-RA 0.202
Tal CG2827 gene product from transcript CG2827-RA 0.201
tsl torso-like 0.200
imd immune deficiency 0.199
lab labial 0.198
Fatp Fatty acid (long chain) transport protein 0.198
CG9897 CG9897 gene product from transcript CG9897-RA 0.197
Ugt35a UDP-glycosyltransferase 35a 0.197
Ice CG7788 gene product from transcript CG7788-RA 0.196
CG5362 CG5362 gene product from transcript CG5362-RA 0.190
Galpha49B G protein alpha49B 0.188
bsk basket 0.187
Catsup Catecholamines up 0.186
Ser Serrate 0.186
Apc APC-like 0.185
Obp99b Odorant-binding protein 99b 0.183
p38b CG7393 gene product from transcript CG7393-RA 0.178
fog folded gastrulation 0.178
sad shadow 0.174
dsf dissatisfaction 0.173
Amy-d Amylase distal 0.173
PGRP-SA Peptidoglycan recognition protein SA 0.173
raps rapsynoid 0.173
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Thrb thyroid hormone receptor beta 0.990
Lhx3 LIM homeobox protein 3 0.986
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.984
Pax8 paired box gene 8 0.967
Pax2 paired box gene 2 0.967
Apoe apolipoprotein E 0.958
Kl klotho 0.953
Tyrp1 tyrosinase-related protein 1 0.943
Lepr leptin receptor 0.940
Bmp4 bone morphogenetic protein 4 0.931
Pten phosphatase and tensin homolog 0.931
Ldlr low density lipoprotein receptor 0.924
Lep leptin 0.919
Tyr tyrosinase 0.917
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.901
Mvd mevalonate (diphospho) decarboxylase 0.900
Vdr vitamin D receptor 0.897
Hand1 heart and neural crest derivatives expressed transcript 1 0.893
Dab1 disabled homolog 1 (Drosophila) 0.892
Apoa1 apolipoprotein A-I 0.890
Rxra retinoid X receptor alpha 0.877
Slc12a1 solute carrier family 12, member 1 0.868
Pparg peroxisome proliferator activated receptor gamma 0.860
Onecut1 one cut domain, family member 1 0.849
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.847
Shc3 src homology 2 domain-containing transforming protein C3 0.833
Lyst lysosomal trafficking regulator 0.817
Lhx1 LIM homeobox protein 1 0.804
Mitf microphthalmia-associated transcription factor 0.790
Bcl2 B-cell leukemia/lymphoma 2 0.777
Rarg retinoic acid receptor, gamma 0.769
Drd2 dopamine receptor D2 0.766
Gata6 GATA binding protein 6 0.765
Slc26a4 solute carrier family 26, member 4 0.765
Otx2 orthodenticle homolog 2 (Drosophila) 0.762
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.761
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.756
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.748
Idi1 isopentenyl-diphosphate delta isomerase 0.746
Cyp51 cytochrome P450, family 51 0.746
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.743
Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 0.741
Npas1 neuronal PAS domain protein 1 0.741
Wnt4 wingless-related MMTV integration site 4 0.730
G6pc glucose-6-phosphatase, catalytic 0.726
Tnf tumor necrosis factor 0.717
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.716
Cps1 carbamoyl-phosphate synthetase 1 0.692
Prox1 prospero-related homeobox 1 0.685
Crp C-reactive protein, pentraxin-related 0.682
Emx1 empty spiracles homolog 1 (Drosophila) 0.675
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.666
Pdx1 pancreatic and duodenal homeobox 1 0.664
Ppara peroxisome proliferator activated receptor alpha 0.654
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.651
Apoa5 apolipoprotein A-V 0.650
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.647
Hnf4a hepatic nuclear factor 4, alpha 0.636
Hand2 heart and neural crest derivatives expressed transcript 2 0.630
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.629
Gdf11 growth differentiation factor 11 0.627
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.625
Fgf8 fibroblast growth factor 8 0.625
Dhcr24 24-dehydrocholesterol reductase 0.624
Rarb retinoic acid receptor, beta 0.618
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.609
Socs1 suppressor of cytokine signaling 1 0.609
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.604
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.603
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.602
Dmgdh dimethylglycine dehydrogenase precursor 0.598
Lmx1a LIM homeobox transcription factor 1 alpha 0.593
Grid1 glutamate receptor, ionotropic, delta 1 0.590
Otc ornithine transcarbamylase 0.589
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.579
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.576
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.564
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.563
Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 0.563
Kit kit oncogene 0.560
Neurod1 neurogenic differentiation 1 0.559
Bdkrb2 bradykinin receptor, beta 2 0.559
Ptafr platelet-activating factor receptor 0.558
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.556
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.555
Pigr polymeric immunoglobulin receptor 0.554
Ar androgen receptor 0.548
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.548
App amyloid beta (A4) precursor protein 0.547
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.542
Inhbe inhibin beta E 0.542
Srcin1 SRC kinase signaling inhibitor 1 0.541
Vav2 vav 2 oncogene 0.539
Npc1 Niemann Pick type C1 0.538
Pax3 paired box gene 3 0.536
Apob apolipoprotein B 0.536
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.535
Cfh complement component factor h 0.530
Apoh apolipoprotein H 0.526
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.517
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.665
Pnlip pancreatic lipase 0.604
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.585
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.480
Sc4mol sterol-C4-methyl oxidase-like 0.479
Akr1c18 aldo-keto reductase family 1, member C18 0.441
Prl prolactin 0.421
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.399
Idi1 isopentenyl-diphosphate delta isomerase 1 0.387
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.385
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.377
Hes2 hairy and enhancer of split 2 (Drosophila) 0.368
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.366
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.366
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.365
Acmsd aminocarboxymuconate semialdehyde decarboxylase 0.359
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.352
Fabp1 fatty acid binding protein 1, liver 0.349
Kl Klotho 0.339
Il10 interleukin 10 0.326
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.323
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.317
Clock clock homolog (mouse) 0.305
Cpb1 carboxypeptidase B1 (tissue) 0.299
Cyp51 cytochrome P450, family 51 0.298
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.298
Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.296
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.294
Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.283
Ncr1 natural cytotoxicity triggering receptor 1 0.278
Omp olfactory marker protein 0.274
Ech1 enoyl coenzyme A hydratase 1, peroxisomal 0.274
Vom1r93 vomeronasal 1 receptor 93 0.265
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.263
Pon1 paraoxonase 1 0.263
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.258
Calcr calcitonin receptor 0.233
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.232
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.231
Glra1 glycine receptor, alpha 1 0.227
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.226
Dio2 deiodinase, iodothyronine, type II 0.226
Dhcr7 7-dehydrocholesterol reductase 0.225
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.224
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.223
Star steroidogenic acute regulatory protein 0.219
Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 0.216
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 0.215
Ces1c carboxylesterase 1C 0.212
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.203
LOC246267 resection-induced TPI (rs11) 0.200
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.198
Prlr prolactin receptor 0.194
Acaa2 acetyl-Coenzyme A acyltransferase 2 0.193
Clps colipase, pancreatic 0.191
Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 0.191
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.189
Slc6a18 solute carrier family 6, member 18 0.186
LOC293989 cytochrome P450-like 0.184
Ccr3 chemokine (C-C motif) receptor 3 0.184
Alox15 arachidonate 15-lipoxygenase 0.183
Mc3r melanocortin 3 receptor 0.182
Unc13c unc-13 homolog C (C. elegans) 0.176
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.176
Cd36 CD36 molecule (thrombospondin receptor) 0.173
Aqp8 aquaporin 8 0.169
Ltb4r leukotriene B4 receptor 0.168
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.168
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 0.164
Snap25 synaptosomal-associated protein 25 0.162
Impg2 interphotoreceptor matrix proteoglycan 2 0.162
Rap1b RAP1B, member of RAS oncogene family 0.162
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.162
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.161
Grp gastrin releasing peptide 0.161
Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 0.160
Dbp D site of albumin promoter (albumin D-box) binding protein 0.159
Dao D-amino-acid oxidase 0.159
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.158
Cbs cystathionine beta synthase 0.157
Acadm acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain 0.157
Rnase4 ribonuclease, RNase A family 4 0.157
Ces1d carboxylesterase 1D 0.155
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.151
Slc25a5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.151
Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.150
Slc9a3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.149
Zg16 zymogen granule protein 16 0.148
Gfra2 GDNF family receptor alpha 2 0.143
Gucy2f guanylate cyclase 2F 0.142
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.142
Serpinb3 serine protease inhibitor B3 0.141
Sv2c synaptic vesicle glycoprotein 2c 0.141
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.141
Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) 0.139
Cela1 chymotrypsin-like elastase family, member 1 0.139
Ugt2a1 UDP glucuronosyltransferase 2 family, polypeptide A1 0.137
Amph amphiphysin 0.136
Fasn fatty acid synthase 0.135
Mep1a meprin 1 alpha 0.135
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ERG11 Erg11p 0.995
ERG25 Erg25p 0.993
ERG26 Erg26p 0.988
ERG3 Erg3p 0.984
ERG2 Erg2p 0.981
ERG5 Erg5p 0.971
ERG7 Erg7p 0.900
ERG27 Erg27p 0.894
ERG6 Erg6p 0.888
ERG28 Erg28p 0.866
SNZ2 Snz2p 0.858
ERG24 Erg24p 0.823
ERG1 Erg1p 0.777
EHT1 Eht1p 0.775
ERG4 Erg4p 0.770
CYB5 Cyb5p 0.747
SNF5 Snf5p 0.745
ERG8 Erg8p 0.734
HMG1 Hmg1p 0.650
ERG12 Erg12p 0.534
MVD1 Mvd1p 0.532
ARO9 Aro9p 0.523
SOR1 Sor1p 0.461
SNZ1 Snz1p 0.451
SNO2 Sno2p 0.437
SSH1 Ssh1p 0.395
SNO1 Sno1p 0.390
YJU3 Yju3p 0.364
CPT1 Cpt1p 0.349
SOR2 Sor2p 0.344
SAM2 Sam2p 0.329
SNO4 Sno4p 0.296
SNO3 Sno3p 0.295
LYS5 Lys5p 0.294
SOL1 Sol1p 0.292
ERG9 Erg9p 0.272
HRK1 Hrk1p 0.271
SAC1 Sac1p 0.267
CTI6 Cti6p 0.264
ACS1 Acs1p 0.262
ERG10 Erg10p 0.261
HFD1 Hfd1p 0.258
ADH1 Adh1p 0.257
SIN3 Sin3p 0.255
MIG2 Mig2p 0.246
PDC5 Pdc5p 0.235
SNZ3 Snz3p 0.224
MGA2 Mga2p 0.223
YEH1 Yeh1p 0.217
ERG13 Erg13p 0.217
HXK2 Hxk2p 0.216
HMG2 Hmg2p 0.212
PSD2 Psd2p 0.207
MSC7 Msc7p 0.207
SWI1 Swi1p 0.206
RTG3 Rtg3p 0.204
RBD2 Rbd2p 0.204
UPC2 Upc2p 0.202
PBA1 Pba1p 0.198
CDS1 Cds1p 0.198
MIG3 Mig3p 0.193
SUM1 Sum1p 0.192
CKA2 Cka2p 0.190
ADH2 Adh2p 0.189
TOM1 Tom1p 0.188
PTC1 Ptc1p 0.186
CTF13 Ctf13p 0.180
NCP1 Ncp1p 0.180
ALD6 Ald6p 0.179
BRO1 Bro1p 0.178
ARE2 Are2p 0.177
PNS1 Pns1p 0.176
KCS1 Kcs1p 0.176
ROX1 Rox1p 0.176
HOR2 Hor2p 0.176
SCM4 Scm4p 0.174
MSC1 Msc1p 0.173
APN1 Apn1p 0.171
HSP42 Hsp42p 0.170
GND1 Gnd1p 0.170
MBR1 Mbr1p 0.165
KES1 Kes1p 0.159
XKS1 Xks1p 0.158
ATF2 Atf2p 0.158
LYS12 Lys12p 0.157
RGT1 Rgt1p 0.156
PDR17 Pdr17p 0.155
LAC1 Lac1p 0.155
YIG1 Yig1p 0.153
YNL035C hypothetical protein 0.147
BUL2 Bul2p 0.147
INO1 Ino1p 0.144
UBP15 Ubp15p 0.142
RHR2 Rhr2p 0.142
UBX6 Ubx6p 0.137
DAL81 Dal81p 0.136
ZAP1 Zap1p 0.134
SSM4 Ssm4p 0.134
CHO2 Cho2p 0.133
AFT1 Aft1p 0.133