The network for 'regulation of lipid kinase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of lipid kinase activity

Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.

Homo sapiens
Name Description Probability Func Analog Organism
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
FGF1 fibroblast growth factor 1 (acidic) 0.999
FGFR2 fibroblast growth factor receptor 2 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
EGFR epidermal growth factor receptor 0.996
FYN FYN oncogene related to SRC, FGR, YES 0.996
PLCG1 phospholipase C, gamma 1 0.995
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.994
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.992
GRB7 growth factor receptor-bound protein 7 0.992
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.981
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.977
FGFR1 fibroblast growth factor receptor 1 0.973
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.962
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.954
CCR5 chemokine (C-C motif) receptor 5 0.943
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.916
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.915
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.909
CCL4 chemokine (C-C motif) ligand 4 0.908
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.841
NRP1 neuropilin 1 0.812
ANGPT2 angiopoietin 2 0.806
VEGFA vascular endothelial growth factor A 0.799
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.791
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.750
SYK spleen tyrosine kinase 0.746
GRB2 growth factor receptor-bound protein 2 0.650
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.521
SPRR2A small proline-rich protein 2A 0.501
CXCL9 chemokine (C-X-C motif) ligand 9 0.471
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.470
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.464
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.417
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.395
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.375
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.366
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.357
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.279
MED25 mediator complex subunit 25 0.277
PTK6 PTK6 protein tyrosine kinase 6 0.270
HCK hemopoietic cell kinase 0.266
CCR7 chemokine (C-C motif) receptor 7 0.250
CCL19 chemokine (C-C motif) ligand 19 0.248
MED28 mediator complex subunit 28 0.227
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.225
GRB10 growth factor receptor-bound protein 10 0.205
PDGFA platelet-derived growth factor alpha polypeptide 0.200
BLNK B-cell linker 0.198
CCL5 chemokine (C-C motif) ligand 5 0.185
FGF10 fibroblast growth factor 10 0.179
CCL13 chemokine (C-C motif) ligand 13 0.166
IL8 interleukin 8 0.162
ZNF746 zinc finger protein 746 0.158
VAV3 vav 3 guanine nucleotide exchange factor 0.147
BCAR1 breast cancer anti-estrogen resistance 1 0.145
GAB1 GRB2-associated binding protein 1 0.143
ITK IL2-inducible T-cell kinase 0.129
BCL2 B-cell CLL/lymphoma 2 0.128
TGFB3 transforming growth factor, beta 3 0.126
CXCL11 chemokine (C-X-C motif) ligand 11 0.124
CCL22 chemokine (C-C motif) ligand 22 0.120
ANGPT1 angiopoietin 1 0.118
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.104
CD81 CD81 molecule 0.102
CCL8 chemokine (C-C motif) ligand 8 0.094
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.089
ENG endoglin 0.088
DPP4 dipeptidyl-peptidase 4 0.086
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.085
TNS3 tensin 3 0.084
SLA Src-like-adaptor 0.084
IDE insulin-degrading enzyme 0.083
IL7R interleukin 7 receptor 0.081
RB1 retinoblastoma 1 0.080
RXRA retinoid X receptor, alpha 0.077
CXCL13 chemokine (C-X-C motif) ligand 13 0.076
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.074
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.073
MATK megakaryocyte-associated tyrosine kinase 0.071
VCAM1 vascular cell adhesion molecule 1 0.070
VAV1 vav 1 guanine nucleotide exchange factor 0.070
CCL2 chemokine (C-C motif) ligand 2 0.069
IGF1R insulin-like growth factor 1 receptor 0.068
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.068
CCL3 chemokine (C-C motif) ligand 3 0.067
NRG1 neuregulin 1 0.067
CD63 CD63 molecule 0.064
FGF2 fibroblast growth factor 2 (basic) 0.061
GAS7 growth arrest-specific 7 0.058
ETF1 eukaryotic translation termination factor 1 0.058
CD9 CD9 molecule 0.057
PTPRB protein tyrosine phosphatase, receptor type, B 0.057
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.056
INSR insulin receptor 0.056
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.055
PGF placental growth factor 0.054
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.053
THBS1 thrombospondin 1 0.051
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.729
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.503
scb scab 0.265
babo baboon 0.201
repo reversed polarity 0.187
S6k RPS6-p70-protein kinase 0.161
zfh1 Zn finger homeodomain 1 0.125
aop anterior open 0.124
Cdc42 CG12530 gene product from transcript CG12530-RA 0.091
Pten CG5671 gene product from transcript CG5671-RB 0.087
dm diminutive 0.075
rl rolled 0.073
drpr draper 0.072
yki yorkie 0.072
par-1 CG8201 gene product from transcript CG8201-RA 0.069
Thor CG8846 gene product from transcript CG8846-RA 0.069
Vrp1 Verprolin 1 0.067
mbc myoblast city 0.060
ena enabled 0.059
stumps CG31317 gene product from transcript CG31317-RC 0.056
Ephrin CG1862 gene product from transcript CG1862-RA 0.053
Akt1 CG4006 gene product from transcript CG4006-RA 0.048
Stat92E Signal-transducer and activator of transcription protein at 92E 0.047
Atg1 Autophagy-specific gene 1 0.041
Dcr-2 Dicer-2 0.041
Rac1 CG2248 gene product from transcript CG2248-RA 0.040
chico CG5686 gene product from transcript CG5686-RB 0.040
chic chickadee 0.039
myoglianin CG1838 gene product from transcript CG1838-RD 0.039
Pk61C Protein kinase 61C 0.039
ttv tout-velu 0.038
Hem HEM-protein 0.032
Dhc64C Dynein heavy chain 64C 0.032
Src64B Src oncogene at 64B 0.031
Rho1 CG8416 gene product from transcript CG8416-RB 0.029
DNApol-alpha60 DNA polymerase alpha 60kD 0.028
RhoL rho-like 0.028
Pvr PDGF- and VEGF-receptor related 0.028
da daughterless 0.028
bnl branchless 0.027
stai stathmin 0.027
phl pole hole 0.027
wun wunen 0.026
Mrtf Myocardin-related transcription factor 0.026
Rac2 CG8556 gene product from transcript CG8556-RA 0.024
bsk basket 0.024
shrb shrub 0.023
pnt pointed 0.023
Dlic Dynein light intermediate chain 0.023
mys myospheroid 0.022
rols rolling pebbles 0.022
insc inscuteable 0.021
Dad Daughters against dpp 0.021
pan pangolin 0.019
hd humpty dumpty 0.019
betaInt-nu beta[nu] integrin 0.019
ttk tramtrack 0.019
Ptp61F Protein tyrosine phosphatase 61F 0.019
kon kon-tiki 0.019
Rab11 Rab-protein 11 0.018
vav CG7893 gene product from transcript CG7893-RB 0.018
LanA Laminin A 0.018
Src42A Src oncogene at 42A 0.018
Smox Smad on X 0.018
slif slimfast 0.017
Gadd45 CG11086 gene product from transcript CG11086-RA 0.017
egh egghead 0.016
Rab7 Rab-protein 7 0.016
blow blown fuse 0.016
nvy nervy 0.016
G-oalpha47A G protein oalpha 47A 0.016
dock dreadlocks 0.016
foxo forkhead box, sub-group O 0.016
rin rasputin 0.015
Cip4 CG15015 gene product from transcript CG15015-RA 0.015
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.015
alpha-Man-I alpha Mannosidase I 0.015
InR Insulin-like receptor 0.015
mip120 Myb-interacting protein 120 0.015
Cat Catalase 0.015
ImpL2 Ecdysone-inducible gene L2 0.015
RN-tre tre oncogene-related protein 0.014
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.014
Rab5 Rab-protein 5 0.014
mav maverick 0.014
Lnk CG17367 gene product from transcript CG17367-RC 0.013
trc tricornered 0.013
spi spitz 0.013
baz bazooka 0.013
twi twist 0.013
Ced-12 CG5336 gene product from transcript CG5336-RA 0.013
Ilp6 Insulin-like peptide 6 0.013
byn brachyenteron 0.013
plexA plexin A 0.013
LanB2 Laminin B2 0.013
Hcf Host cell factor 0.012
trbl tribbles 0.012
l(2)k16918 lethal (2) k16918 0.012
ci cubitus interruptus 0.012
sr stripe 0.012
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Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 0.998
Trp53 transformation related protein 53 0.968
Ctnnb1 catenin (cadherin associated protein), beta 1 0.947
Klk1b5 kallikrein 1-related peptidase b5 0.938
Lepr leptin receptor 0.860
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.851
Efnb2 ephrin B2 0.787
Klk1b8 kallikrein 1-related peptidase b8 0.763
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.739
Tgfb1 transforming growth factor, beta 1 0.734
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.693
Esr1 estrogen receptor 1 (alpha) 0.687
Klk1b26 kallikrein 1-related petidase b26 0.664
Nos3 nitric oxide synthase 3, endothelial cell 0.636
Fyn Fyn proto-oncogene 0.579
Grb2 growth factor receptor bound protein 2 0.544
Irs1 insulin receptor substrate 1 0.493
Klk1b1 kallikrein 1-related peptidase b1 0.460
Ctrb1 chymotrypsinogen B1 0.460
2210010C04Rik RIKEN cDNA 2210010C04 gene 0.404
Klk1 kallikrein 1 0.386
Csf1 colony stimulating factor 1 (macrophage) 0.374
Col1a1 collagen, type I, alpha 1 0.364
Klk1b16 kallikrein 1-related peptidase b16 0.356
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.323
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.319
Cbl Casitas B-lineage lymphoma 0.318
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.310
Klk1b21 kallikrein 1-related peptidase b21 0.309
Kit kit oncogene 0.301
Lyz2 lysozyme 2 0.293
Klk1b4 kallikrein 1-related pepidase b4 0.284
Psen1 presenilin 1 0.261
Ephb2 Eph receptor B2 0.214
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.205
Klk1b27 kallikrein 1-related peptidase b27 0.190
Klk1b11 kallikrein 1-related peptidase b11 0.174
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.174
Notch1 Notch gene homolog 1 (Drosophila) 0.173
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.173
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.155
Cela2a chymotrypsin-like elastase family, member 2A 0.154
Apc adenomatosis polyposis coli 0.152
Klk1b3 kallikrein 1-related peptidase b3 0.149
Emx1 empty spiracles homolog 1 (Drosophila) 0.147
Fas Fas (TNF receptor superfamily member 6) 0.142
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.142
Nf1 neurofibromatosis 1 0.141
Ins2 insulin II 0.141
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.137
Apoe apolipoprotein E 0.135
Mdm2 transformed mouse 3T3 cell double minute 2 0.130
Cd44 CD44 antigen 0.130
Klk1b9 kallikrein 1-related peptidase b9 0.130
Thra thyroid hormone receptor alpha 0.125
Ghr growth hormone receptor 0.124
Braf Braf transforming gene 0.116
Egfr epidermal growth factor receptor 0.116
Grb10 growth factor receptor bound protein 10 0.114
Klk1b24 kallikrein 1-related peptidase b24 0.109
Pparg peroxisome proliferator activated receptor gamma 0.108
Vdr vitamin D receptor 0.105
Dab1 disabled homolog 1 (Drosophila) 0.104
Hif1a hypoxia inducible factor 1, alpha subunit 0.103
Fgfr2 fibroblast growth factor receptor 2 0.099
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.096
Was Wiskott-Aldrich syndrome homolog (human) 0.091
Notch2 Notch gene homolog 2 (Drosophila) 0.090
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.087
Pik3cb phosphatidylinositol 3-kinase, catalytic, beta polypeptide 0.080
Ptpre protein tyrosine phosphatase, receptor type, E 0.070
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.068
Rac1 RAS-related C3 botulinum substrate 1 0.065
Prkce protein kinase C, epsilon 0.061
Epha4 Eph receptor A4 0.061
Zg16 zymogen granule protein 16 0.060
Sykb spleen tyrosine kinase 0.058
Efnb1 ephrin B1 0.058
Pycard PYD and CARD domain containing 0.057
Cd19 CD19 antigen 0.057
Blnk B-cell linker 0.056
Ptk2 PTK2 protein tyrosine kinase 2 0.054
Pcdh12 protocadherin 12 0.054
Prss2 protease, serine, 2 0.054
5430421N21Rik RIKEN cDNA 5430421N21 gene 0.053
Rb1 retinoblastoma 1 0.053
Nphp3 nephronophthisis 3 (adolescent) 0.052
Ephb3 Eph receptor B3 0.051
Krt17 keratin 17 0.050
Adam17 a disintegrin and metallopeptidase domain 17 0.048
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.047
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.046
Sox9 SRY-box containing gene 9 0.045
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.045
Insr insulin receptor 0.045
Krt14 keratin 14 0.045
Src Rous sarcoma oncogene 0.044
Cav1 caveolin 1, caveolae protein 0.044
Hcls1 hematopoietic cell specific Lyn substrate 1 0.043
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.042
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Rattus norvegicus
Name Description Probability Func Analog Organism
Dbp D site of albumin promoter (albumin D-box) binding protein 0.285
Itm2b integral membrane protein 2B 0.273
Fgfr1 Fibroblast growth factor receptor 1 0.132
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.122
Sirpa signal-regulatory protein alpha 0.106
Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.063
Prkcd protein kinase C, delta 0.051
Epas1 endothelial PAS domain protein 1 0.050
RT1-DOa RT1 class II, locus DOa 0.049
Epn1 Epsin 1 0.033
Klk1c10l2 kallikrein 1-related peptidase c10-like 2 0.031
Hk1 hexokinase 1 0.026
Irs3 insulin receptor substrate 3 0.022
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.022
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.021
Klk8 kallikrein related-peptidase 8 0.020
Klk1b21 kallikrein 1-related peptidase b21 0.019
Cd8a CD8a molecule 0.018
Crip2 cysteine-rich protein 2 0.016
Cobll1 Cobl-like 1 0.016
Klf2 Kruppel-like factor 2 (lung) 0.015
Sox17 SRY (sex determining region Y)-box 17 0.015
Gata3 GATA binding protein 3 0.015
Ddr1 discoidin domain receptor tyrosine kinase 1 0.015
Plcg2 phospholipase C, gamma 2 0.015
Il2rg interleukin 2 receptor, gamma 0.014
Ptms parathymosin 0.013
Klk1 kallikrein 1 0.013
Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.013
Arhgap27 Rho GTPase activating protein 27 0.013
Bhlha15 basic helix-loop-helix family, member a15 0.013
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.013
Capn1 calpain 1 0.012
Klf6 Kruppel-like factor 6 0.012
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.012
Adar adenosine deaminase, RNA-specific 0.012
Tsc22d3 TSC22 domain family, member 3 0.011
Grik5 glutamate receptor, ionotropic, kainate 5 0.011
Stat6 signal transducer and activator of transcription 6 0.011
March8 membrane-associated ring finger (C3HC4) 8 0.011
Cd37 CD37 molecule 0.011
Batf basic leucine zipper transcription factor, ATF-like 0.010
Arrdc1 arrestin domain containing 1 0.010
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism