The network for 'regulation of dephosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dephosphorylation

Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.

Homo sapiens
Name Description Probability Func Analog Organism
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.998
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.953
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.923
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.915
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.893
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.887
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.757
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.720
ACTB actin, beta 0.682
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.655
PPP6C protein phosphatase 6, catalytic subunit 0.586
CDK1 cyclin-dependent kinase 1 0.564
FHL2 four and a half LIM domains 2 0.533
RIPK3 receptor-interacting serine-threonine kinase 3 0.470
ANKRD28 ankyrin repeat domain 28 0.412
PTPRC protein tyrosine phosphatase, receptor type, C 0.381
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.377
LAT linker for activation of T cells 0.348
TSC2 tuberous sclerosis 2 0.346
MAPK1 mitogen-activated protein kinase 1 0.333
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.314
HDAC4 histone deacetylase 4 0.313
BIRC2 baculoviral IAP repeat containing 2 0.312
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.310
CASC5 cancer susceptibility candidate 5 0.304
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.304
ADORA2A adenosine A2a receptor 0.277
ZFYVE9 zinc finger, FYVE domain containing 9 0.264
KIAA1683 KIAA1683 0.245
TCTEX1D4 Tctex1 domain containing 4 0.229
SH3RF1 SH3 domain containing ring finger 1 0.227
MPRIP myosin phosphatase Rho interacting protein 0.222
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.211
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.198
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.189
ANKRD52 ankyrin repeat domain 52 0.188
AFF4 AF4/FMR2 family, member 4 0.184
BMPR1A bone morphogenetic protein receptor, type IA 0.183
PTEN phosphatase and tensin homolog 0.183
VEGFA vascular endothelial growth factor A 0.178
TSSK2 testis-specific serine kinase 2 0.176
GDA guanine deaminase 0.176
SET SET nuclear oncogene 0.174
CDK2 cyclin-dependent kinase 2 0.171
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.155
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.148
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.143
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.141
PPP6R1 protein phosphatase 6, regulatory subunit 1 0.140
PBK PDZ binding kinase 0.139
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.135
PPP1R8 protein phosphatase 1, regulatory (inhibitor) subunit 8 0.134
NRP1 neuropilin 1 0.134
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.131
SNF8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.128
ADRB1 adrenergic, beta-1-, receptor 0.123
TGFBR1 transforming growth factor, beta receptor 1 0.121
PKM2 pyruvate kinase, muscle 0.121
EAF1 ELL associated factor 1 0.120
ACVR1B activin A receptor, type IB 0.120
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.112
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.112
FANCC Fanconi anemia, complementation group C 0.110
RLN3 relaxin 3 0.110
KLHL3 kelch-like 3 (Drosophila) 0.104
MYO10 myosin X 0.098
OPTN optineurin 0.097
PPP1R10 protein phosphatase 1, regulatory (inhibitor) subunit 10 0.095
CCNB1 cyclin B1 0.094
TP53BP2 tumor protein p53 binding protein, 2 0.090
FASLG Fas ligand (TNF superfamily, member 6) 0.090
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.088
CDHR2 cadherin-related family member 2 0.087
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.087
SFN stratifin 0.086
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.085
FN1 fibronectin 1 0.085
TRAF1 TNF receptor-associated factor 1 0.085
LMTK2 lemur tyrosine kinase 2 0.084
MARK2 MAP/microtubule affinity-regulating kinase 2 0.084
ENG endoglin 0.081
TFF1 trefoil factor 1 0.081
ZBTB16 zinc finger and BTB domain containing 16 0.081
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.081
C11orf66 chromosome 11 open reading frame 66 0.080
BTBD10 BTB (POZ) domain containing 10 0.079
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.078
KIAA1949 KIAA1949 0.077
CDC25B cell division cycle 25 homolog B (S. pombe) 0.076
NOXA1 NADPH oxidase activator 1 0.076
EPRS glutamyl-prolyl-tRNA synthetase 0.075
PPP1R13B protein phosphatase 1, regulatory (inhibitor) subunit 13B 0.075
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.075
BIRC3 baculoviral IAP repeat containing 3 0.073
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.073
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.073
PPP1R15B protein phosphatase 1, regulatory (inhibitor) subunit 15B 0.073
PFN1 profilin 1 0.072
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.070
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.070
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
C17G10.1 Protein C17G10.1 0.011
F33G12.2 Protein F33G12.2 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Rpgrip1l Rpgrip1-like 0.607
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.543
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.431
Lepr leptin receptor 0.352
Tnf tumor necrosis factor 0.340
Dlg4 discs, large homolog 4 (Drosophila) 0.333
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.330
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.289
Ifng interferon gamma 0.284
Cdk1 cyclin-dependent kinase 1 0.183
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.121
Lta lymphotoxin A 0.116
Ncoa3 nuclear receptor coactivator 3 0.114
Lrrk2 leucine-rich repeat kinase 2 0.110
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.108
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.094
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.092
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.091
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.088
Acvr1 activin A receptor, type 1 0.082
Ccna2 cyclin A2 0.082
Nos3 nitric oxide synthase 3, endothelial cell 0.076
Snap25 synaptosomal-associated protein 25 0.073
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.071
Hdac4 histone deacetylase 4 0.067
Ltb lymphotoxin B 0.064
Tsc2 tuberous sclerosis 2 0.063
Vdr vitamin D receptor 0.061
Apc adenomatosis polyposis coli 0.055
Agtr2 angiotensin II receptor, type 2 0.053
Manf mesencephalic astrocyte-derived neurotrophic factor 0.051
Csf1 colony stimulating factor 1 (macrophage) 0.048
Nf2 neurofibromatosis 2 0.044
Agrp agouti related protein 0.043
Trp53 transformation related protein 53 0.042
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.041
Tgfbr2 transforming growth factor, beta receptor II 0.040
Mef2d myocyte enhancer factor 2D 0.038
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.038
Nodal nodal 0.038
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.038
Ccnb1 cyclin B1 0.035
Cxcr5 chemokine (C-X-C motif) receptor 5 0.033
Ret ret proto-oncogene 0.033
Nf1 neurofibromatosis 1 0.032
Nos1 nitric oxide synthase 1, neuronal 0.031
Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta 0.030
Rab25 RAB25, member RAS oncogene family 0.030
Plk1 polo-like kinase 1 (Drosophila) 0.029
Qk quaking 0.028
Zeb2 zinc finger E-box binding homeobox 2 0.028
Il7 interleukin 7 0.027
Ube2c ubiquitin-conjugating enzyme E2C 0.027
Mgat3 mannoside acetylglucosaminyltransferase 3 0.027
Prc1 protein regulator of cytokinesis 1 0.026
Calm1 calmodulin 1 0.026
Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like 0.025
Hdac5 histone deacetylase 5 0.024
Il10 interleukin 10 0.024
Kif20a kinesin family member 20A 0.024
Cd44 CD44 antigen 0.023
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.023
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.023
Hspa1b heat shock protein 1B 0.023
Tox thymocyte selection-associated high mobility group box 0.022
Igh immunoglobulin heavy chain complex 0.022
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.022
Adcy9 adenylate cyclase 9 0.022
0610031J06Rik RIKEN cDNA 0610031J06 gene 0.021
Plxna4 plexin A4 0.021
9130017N09Rik RIKEN cDNA 9130017N09 gene 0.020
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.019
Tlr2 toll-like receptor 2 0.019
Syn2 synapsin II 0.019
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.019
Ttn titin 0.018
Hspa5 heat shock protein 5 0.018
Hand1 heart and neural crest derivatives expressed transcript 1 0.018
Nptx1 neuronal pentraxin 1 0.018
Wdr45 WD repeat domain 45 0.017
Gja1 gap junction protein, alpha 1 0.017
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.017
Kif22 kinesin family member 22 0.017
Pcbp1 poly(rC) binding protein 1 0.017
Ube2e1 ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast) 0.017
Grn granulin 0.016
Sez6l seizure related 6 homolog like 0.016
Aurka aurora kinase A 0.016
Ptgs2 prostaglandin-endoperoxide synthase 2 0.016
Col4a3 collagen, type IV, alpha 3 0.016
Hdac7 histone deacetylase 7 0.015
Tgfb2 transforming growth factor, beta 2 0.015
Cxcl13 chemokine (C-X-C motif) ligand 13 0.015
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.015
Zeb1 zinc finger E-box binding homeobox 1 0.015
Tsr1 TSR1, 20S rRNA accumulation, homolog (yeast) 0.015
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.015
Fam83g family with sequence similarity 83, member G 0.015
Scn11a sodium channel, voltage-gated, type XI, alpha 0.015
Ckap2 cytoskeleton associated protein 2 0.015
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rpl11 ribosomal protein L11 0.021
Rps27a ribosomal protein S27a 0.016
Rpl10 ribosomal protein L10 0.014
Rpsa ribosomal protein SA 0.014
Rps16 ribosomal protein S16 0.013
Rpl5 ribosomal protein L5 0.012
Rpl37 ribosomal protein L37 0.011
Rpl22 ribosomal protein L22 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SDS22 Sds22p 0.581
CKS1 Cks1p 0.355
KDX1 Kdx1p 0.277
RSN1 Rsn1p 0.104
CLB1 Clb1p 0.098
PPZ1 Ppz1p 0.079
TFG2 Tfg2p 0.074
CLB3 Clb3p 0.065
RPB11 Rpb11p 0.064
YPI1 Ypi1p 0.058
BMH2 Bmh2p 0.053
CAB3 Cab3p 0.051
PDS1 Pds1p 0.050
ZPR1 Zpr1p 0.050
SFG1 Sfg1p 0.048
PKC1 Pkc1p 0.047
OSH2 Osh2p 0.046
CLB5 Clb5p 0.045
GIP2 Gip2p 0.042
SIC1 Sic1p 0.041
CLB4 Clb4p 0.040
YGR210C hypothetical protein 0.038
CLN1 Cln1p 0.037
SWE1 Swe1p 0.036
FIN1 Fin1p 0.036
RRP17 Rrp17p 0.034
TYW1 Tyw1p 0.030
PTI1 Pti1p 0.029
PDS5 Pds5p 0.029
GIP3 Gip3p 0.028
GLC7 Glc7p 0.027
FPR3 Fpr3p 0.025
RHO1 Rho1p 0.025
IST2 Ist2p 0.024
CDC15 Cdc15p 0.024
LTV1 Ltv1p 0.023
PPQ1 Ppq1p 0.022
GCS1 Gcs1p 0.022
ABP140 Abp140p 0.022
POG1 Pog1p 0.022
CLN2 Cln2p 0.021
PTC3 Ptc3p 0.021
KEL3 Kel3p 0.021
WWM1 Wwm1p 0.021
SOK1 Sok1p 0.020
GAT1 Gat1p 0.020
YLR264C-A hypothetical protein 0.020
PSK1 Psk1p 0.019
CLB6 Clb6p 0.019
TED1 Ted1p 0.019
APM1 Apm1p 0.019
FPK1 Fpk1p 0.019
HAC1 Hac1p 0.019
URA3 Ura3p 0.019
SRD1 Srd1p 0.019
PAN1 Pan1p 0.018
WSC4 Wsc4p 0.018
SRP54 Srp54p 0.018
YLR162W hypothetical protein 0.018
JIP4 Jip4p 0.018
PTC2 Ptc2p 0.018
LEU2 Leu2p 0.018
SAS10 Sas10p 0.018
SUI3 Sui3p 0.017
KSS1 Kss1p 0.017
YBL086C hypothetical protein 0.017
IML1 Iml1p 0.017
FMP48 Fmp48p 0.017
CLB2 Clb2p 0.017
PLM2 Plm2p 0.016
HAL5 Hal5p 0.016
SPC1 Spc1p 0.016
YNL058C hypothetical protein 0.016
BCK2 Bck2p 0.016
YOL038C-A hypothetical protein 0.016
YDL121C hypothetical protein 0.016
ARP10 Arp10p 0.016
GEA2 Gea2p 0.016
YNR014W hypothetical protein 0.016
DNF1 Dnf1p 0.016
RHO5 Rho5p 0.016
YSP2 Ysp2p 0.016
CUP1-1 Cup1-1p 0.016
ARG8 Arg8p 0.015
OYE2 Oye2p 0.015
YIR035C hypothetical protein 0.015
SBE22 Sbe22p 0.015
CDC6 Cdc6p 0.015
ROM1 Rom1p 0.015
OSH3 Osh3p 0.015
MF(ALPHA)2 Mf(alpha)2p 0.015
STU1 Stu1p 0.015
YDL129W hypothetical protein 0.015
SSK1 Ssk1p 0.014
LAC1 Lac1p 0.014
CPD1 Cpd1p 0.014
UTP20 Utp20p 0.014
ITR2 Itr2p 0.014
SSP1 Ssp1p 0.014
SPC97 Spc97p 0.014