The network for 'negative regulation of leukocyte apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of leukocyte apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.

Homo sapiens
Name Description Probability Func Analog Organism
SYK spleen tyrosine kinase 0.996
CCL5 chemokine (C-C motif) ligand 5 0.910
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.855
CCR5 chemokine (C-C motif) receptor 5 0.855
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.844
INSR insulin receptor 0.779
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.726
LCK lymphocyte-specific protein tyrosine kinase 0.680
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.607
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.595
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.566
SH3KBP1 SH3-domain kinase binding protein 1 0.557
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.521
CCL4 chemokine (C-C motif) ligand 4 0.483
EGFR epidermal growth factor receptor 0.467
BID BH3 interacting domain death agonist 0.452
CARD11 caspase recruitment domain family, member 11 0.447
SH2D4A SH2 domain containing 4A 0.430
BMPR1A bone morphogenetic protein receptor, type IA 0.425
CCR1 chemokine (C-C motif) receptor 1 0.416
CXCL9 chemokine (C-X-C motif) ligand 9 0.392
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.387
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.326
AXL AXL receptor tyrosine kinase 0.292
DPP4 dipeptidyl-peptidase 4 0.291
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.259
GAS6 growth arrest-specific 6 0.256
PILRA paired immunoglobin-like type 2 receptor alpha 0.252
FASLG Fas ligand (TNF superfamily, member 6) 0.228
CXCR4 chemokine (C-X-C motif) receptor 4 0.216
LAT linker for activation of T cells 0.207
IGF1R insulin-like growth factor 1 receptor 0.204
DERL1 Der1-like domain family, member 1 0.169
CXCL2 chemokine (C-X-C motif) ligand 2 0.165
MSN moesin 0.151
CXCL10 chemokine (C-X-C motif) ligand 10 0.142
TNF tumor necrosis factor 0.133
GRB2 growth factor receptor-bound protein 2 0.124
EPOR erythropoietin receptor 0.123
SIGLEC7 sialic acid binding Ig-like lectin 7 0.111
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.105
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.103
IL8 interleukin 8 0.100
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.097
IL1B interleukin 1, beta 0.095
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.093
SH3BP2 SH3-domain binding protein 2 0.093
CCL22 chemokine (C-C motif) ligand 22 0.086
NOXA1 NADPH oxidase activator 1 0.085
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.085
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.075
CCR7 chemokine (C-C motif) receptor 7 0.073
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.069
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.068
VCAM1 vascular cell adhesion molecule 1 0.067
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.067
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.066
CCL2 chemokine (C-C motif) ligand 2 0.065
PLEK pleckstrin 0.062
WIPF1 WAS/WASL interacting protein family, member 1 0.060
FAS Fas (TNF receptor superfamily, member 6) 0.058
VCP valosin containing protein 0.055
CCL19 chemokine (C-C motif) ligand 19 0.055
CXCL11 chemokine (C-X-C motif) ligand 11 0.055
IRS1 insulin receptor substrate 1 0.054
C9orf89 chromosome 9 open reading frame 89 0.054
NCF1 neutrophil cytosolic factor 1 0.053
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.052
CCL8 chemokine (C-C motif) ligand 8 0.051
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.050
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.048
IL2RB interleukin 2 receptor, beta 0.047
PTAFR platelet-activating factor receptor 0.045
TRADD TNFRSF1A-associated via death domain 0.045
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.044
BCL3 B-cell CLL/lymphoma 3 0.042
ICAM1 intercellular adhesion molecule 1 0.042
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.040
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.038
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.037
FSTL1 follistatin-like 1 0.037
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.037
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.037
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.037
HCK hemopoietic cell kinase 0.037
IFNG interferon, gamma 0.036
PLXNB1 plexin B1 0.034
CCL13 chemokine (C-C motif) ligand 13 0.034
HK3 hexokinase 3 (white cell) 0.034
CFLAR CASP8 and FADD-like apoptosis regulator 0.034
HLA-DRA major histocompatibility complex, class II, DR alpha 0.034
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.033
KAT2B K(lysine) acetyltransferase 2B 0.032
CCL3 chemokine (C-C motif) ligand 3 0.032
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.031
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.030
IL1RN interleukin 1 receptor antagonist 0.030
CD40 CD40 molecule, TNF receptor superfamily member 5 0.030
CCL11 chemokine (C-C motif) ligand 11 0.028
SOCS3 suppressor of cytokine signaling 3 0.028
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Lyz2 lysozyme 2 0.959
Kit kit oncogene 0.574
Lepr leptin receptor 0.434
Foxp3 forkhead box P3 0.367
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.305
Il1r1 interleukin 1 receptor, type I 0.302
Ccr2 chemokine (C-C motif) receptor 2 0.280
Il6st interleukin 6 signal transducer 0.245
Il2rg interleukin 2 receptor, gamma chain 0.195
Trp53 transformation related protein 53 0.178
Ccl3 chemokine (C-C motif) ligand 3 0.168
Socs1 suppressor of cytokine signaling 1 0.163
Ptprc protein tyrosine phosphatase, receptor type, C 0.159
Ccl2 chemokine (C-C motif) ligand 2 0.152
Rxra retinoid X receptor alpha 0.147
Ccr1 chemokine (C-C motif) receptor 1 0.136
Ifng interferon gamma 0.126
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.124
Cd7 CD7 antigen 0.107
Pdcd1 programmed cell death 1 0.101
Apc adenomatosis polyposis coli 0.094
Nos3 nitric oxide synthase 3, endothelial cell 0.093
Batf basic leucine zipper transcription factor, ATF-like 0.087
Pnp2 purine-nucleoside phosphorylase 2 0.084
Ctnnb1 catenin (cadherin associated protein), beta 1 0.082
Fas Fas (TNF receptor superfamily member 6) 0.081
Lck lymphocyte protein tyrosine kinase 0.081
Tbx21 T-box 21 0.077
Inpp5d inositol polyphosphate-5-phosphatase D 0.077
Fasl Fas ligand (TNF superfamily, member 6) 0.077
Il2rb interleukin 2 receptor, beta chain 0.077
Gzmb granzyme B 0.076
Drd2 dopamine receptor D2 0.075
Ccl4 chemokine (C-C motif) ligand 4 0.071
Cd44 CD44 antigen 0.070
Sh2d2a SH2 domain protein 2A 0.069
Ctsw cathepsin W 0.069
Ikzf1 IKAROS family zinc finger 1 0.069
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.067
Selp selectin, platelet 0.066
Cd96 CD96 antigen 0.063
Cd3e CD3 antigen, epsilon polypeptide 0.063
Mmp9 matrix metallopeptidase 9 0.061
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.060
Csf1 colony stimulating factor 1 (macrophage) 0.060
Tnf tumor necrosis factor 0.059
Irf9 interferon regulatory factor 9 0.056
Ghr growth hormone receptor 0.056
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.054
Tgfb1 transforming growth factor, beta 1 0.054
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.054
Bcl2 B-cell leukemia/lymphoma 2 0.053
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.053
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.050
Lep leptin 0.049
Bak1 BCL2-antagonist/killer 1 0.049
Bax BCL2-associated X protein 0.048
Sit1 suppression inducing transmembrane adaptor 1 0.048
Il10 interleukin 10 0.048
Ccl12 chemokine (C-C motif) ligand 12 0.048
Cd6 CD6 antigen 0.046
Ccl8 chemokine (C-C motif) ligand 8 0.044
Il15ra interleukin 15 receptor, alpha chain 0.043
Pparg peroxisome proliferator activated receptor gamma 0.043
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.042
Rb1 retinoblastoma 1 0.042
Pten phosphatase and tensin homolog 0.042
Cd247 CD247 antigen 0.040
Meox2 mesenchyme homeobox 2 0.040
Prf1 perforin 1 (pore forming protein) 0.039
Traf1 TNF receptor-associated factor 1 0.038
Tlr4 toll-like receptor 4 0.038
Esr1 estrogen receptor 1 (alpha) 0.037
Gzma granzyme A 0.037
Egln1 EGL nine homolog 1 (C. elegans) 0.036
Flt3 FMS-like tyrosine kinase 3 0.036
Gzmk granzyme K 0.035
Itk IL2-inducible T-cell kinase 0.035
Itgax integrin alpha X 0.035
Cd27 CD27 antigen 0.035
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.034
Madcam1 mucosal vascular addressin cell adhesion molecule 1 0.034
Ncr1 natural cytotoxicity triggering receptor 1 0.034
Smad3 MAD homolog 3 (Drosophila) 0.033
Smad4 MAD homolog 4 (Drosophila) 0.033
Il27ra interleukin 27 receptor, alpha 0.033
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.033
Cd2 CD2 antigen 0.033
H2-Oa histocompatibility 2, O region alpha locus 0.032
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.032
Fgfr2 fibroblast growth factor receptor 2 0.032
Cd5 CD5 antigen 0.032
Il18r1 interleukin 18 receptor 1 0.030
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.030
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.029
Cd19 CD19 antigen 0.029
Cma1 chymase 1, mast cell 0.028
Prlr prolactin receptor 0.028
Cish cytokine inducible SH2-containing protein 0.028
Gzmc granzyme C 0.027
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-DMb RT1 class II, locus DMb 0.250
RT1-Da RT1 class II, locus Da 0.070
RT1-Db1 RT1 class II, locus Db1 0.047
Cd37 CD37 molecule 0.045
Gzmk granzyme K 0.042
RT1-Ba RT1 class II, locus Ba 0.036
Aif1 allograft inflammatory factor 1 0.034
Cd247 Cd247 molecule 0.031
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.031
Cd8a CD8a molecule 0.026
Dock8 dedicator of cytokinesis 8 0.026
Ctss cathepsin S 0.025
Nkg7 natural killer cell group 7 sequence 0.025
Il2rb interleukin 2 receptor, beta 0.024
B2m beta-2 microglobulin 0.020
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.020
Tcrb T-cell receptor beta chain 0.017
Faslg Fas ligand (TNF superfamily, member 6) 0.016
Cd53 Cd53 molecule 0.016
Ncr1 natural cytotoxicity triggering receptor 1 0.016
Fgf16 fibroblast growth factor 16 0.015
Gzmb granzyme B 0.015
Arl11 ADP-ribosylation factor-like 11 0.015
Il8ra interleukin 8 receptor, alpha 0.014
Cd2 Cd2 molecule 0.014
Fuca1 fucosidase, alpha-L- 1, tissue 0.014
Ubd ubiquitin D 0.014
Clec9a C-type lectin domain family 9, member a 0.013
Hck hemopoietic cell kinase 0.013
Gfap glial fibrillary acidic protein 0.013
Fgd2 FYVE, RhoGEF and PH domain containing 2 0.012
Fxyd4 FXYD domain-containing ion transport regulator 4 0.012
Cpxm2 carboxypeptidase X (M14 family), member 2 0.012
Inpp5d inositol polyphosphate-5-phosphatase D 0.012
Smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.012
Zap70 zeta-chain (TCR) associated protein kinase 0.012
Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 0.012
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.012
Batf3 basic leucine zipper transcription factor, ATF-like 3 0.012
Fam65b family with sequence similarity 65, member B 0.012
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.011
C1qb complement component 1, q subcomponent, B chain 0.011
Gucy2d guanylate cyclase 2d 0.011
Sell selectin L 0.011
Il2rg interleukin 2 receptor, gamma 0.011
Gzmm granzyme M (lymphocyte met-ase 1) 0.011
Cd3g CD3 molecule, gamma 0.011
Grpr gastrin releasing peptide receptor 0.011
Arhgap4 Rho GTPase activating protein 4 0.011
Parvg parvin, gamma 0.011
Igh-6 immunoglobulin heavy chain 6 0.011
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.011
Il8rb interleukin 8 receptor, beta 0.011
Syt2 synaptotagmin II 0.011
Lcp2 lymphocyte cytosolic protein 2 0.011
Xcl1 chemokine (C motif) ligand 1 0.010
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.010
Cd86 CD86 molecule 0.010
Fcrla Fc receptor-like A 0.010
Ciita class II, major histocompatibility complex, transactivator 0.010
Kif6 kinesin family member 6 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism