IMP
Process View
The network for 'cellular response to increased oxygen levels' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cellular response to increased oxygen levels
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 1.000 | |
| FADD | Fas (TNFRSF6)-associated via death domain | 1.000 | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 1.000 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 1.000 | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 1.000 | |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.999 | |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.997 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.996 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.932 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.875 | |
| CAV2 | caveolin 2 | 0.696 | |
| TRADD | TNFRSF1A-associated via death domain | 0.682 | |
| BID | BH3 interacting domain death agonist | 0.606 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.592 | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.384 | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.352 | |
| AR | androgen receptor | 0.313 | |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.277 | |
| CREBBP | CREB binding protein | 0.261 | |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.130 | |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.116 | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.102 | |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.084 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.066 | |
| PTEN | phosphatase and tensin homolog | 0.063 | |
| NCOA2 | nuclear receptor coactivator 2 | 0.062 | |
| F2R | coagulation factor II (thrombin) receptor | 0.055 | |
| DAXX | death-domain associated protein | 0.054 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.054 | |
| PRDX1 | peroxiredoxin 1 | 0.049 | |
| FOXO3 | forkhead box O3 | 0.049 | |
| POMP | proteasome maturation protein | 0.049 | |
| PRKCDBP | protein kinase C, delta binding protein | 0.046 | |
| FOXO1 | forkhead box O1 | 0.045 | |
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | 0.038 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.035 | |
| FHL2 | four and a half LIM domains 2 | 0.030 | |
| SEC61G | Sec61 gamma subunit | 0.029 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.026 | |
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.025 | |
| TRAF2 | TNF receptor-associated factor 2 | 0.025 | |
| EGR3 | early growth response 3 | 0.024 | |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.024 | |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.023 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.023 | |
| SDPR | serum deprivation response | 0.022 | |
| ESR1 | estrogen receptor 1 | 0.022 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.021 | |
| PTRF | polymerase I and transcript release factor | 0.021 | |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.021 | |
| NCOA6 | nuclear receptor coactivator 6 | 0.019 | |
| EDNRB | endothelin receptor type B | 0.018 | |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.017 | |
| CD59 | CD59 molecule, complement regulatory protein | 0.016 | |
| EGR2 | early growth response 2 | 0.015 | |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.015 | |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.015 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.014 | |
| LDLR | low density lipoprotein receptor | 0.014 | |
| EGFR | epidermal growth factor receptor | 0.014 | |
| IER2 | immediate early response 2 | 0.014 | |
| TXNRD1 | thioredoxin reductase 1 | 0.013 | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.013 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.013 | |
| PROCR | protein C receptor, endothelial | 0.013 | |
| GABARAP | GABA(A) receptor-associated protein | 0.012 | |
| ESRRG | estrogen-related receptor gamma | 0.012 | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.011 | |
| IRF2 | interferon regulatory factor 2 | 0.011 | |
| TUBB6 | tubulin, beta 6 | 0.011 | |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.011 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.011 | |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.011 | |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.011 | |
| DUSP23 | dual specificity phosphatase 23 | 0.011 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Lepr | leptin receptor | 0.973 | |
| Cav1 | caveolin 1, caveolae protein | 0.874 | |
| Apoe | apolipoprotein E | 0.566 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.465 | |
| Ghr | growth hormone receptor | 0.458 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.346 | |
| Lyz2 | lysozyme 2 | 0.206 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.196 | |
| Lep | leptin | 0.184 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.170 | |
| Pten | phosphatase and tensin homolog | 0.132 | |
| Plin1 | perilipin 1 | 0.129 | |
| Lpin1 | lipin 1 | 0.097 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.085 | |
| Fos | FBJ osteosarcoma oncogene | 0.058 | |
| Ar | androgen receptor | 0.052 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.049 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.043 | |
| Vegfa | vascular endothelial growth factor A | 0.039 | |
| Dusp1 | dual specificity phosphatase 1 | 0.037 | |
| Tlr4 | toll-like receptor 4 | 0.036 | |
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.034 | |
| Egr2 | early growth response 2 | 0.033 | |
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.032 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.032 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.031 | |
| Npc1 | Niemann Pick type C1 | 0.030 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.028 | |
| Ldlr | low density lipoprotein receptor | 0.027 | |
| Igf1 | insulin-like growth factor 1 | 0.027 | |
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.026 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.023 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.023 | |
| Il1r1 | interleukin 1 receptor, type I | 0.023 | |
| Bscl2 | Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) | 0.021 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.021 | |
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.020 | |
| Irs2 | insulin receptor substrate 2 | 0.020 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.018 | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.018 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.018 | |
| Ncoa3 | nuclear receptor coactivator 3 | 0.016 | |
| Thra | thyroid hormone receptor alpha | 0.016 | |
| Kit | kit oncogene | 0.016 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.015 | |
| Vdr | vitamin D receptor | 0.015 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.015 | |
| Casp8 | caspase 8 | 0.015 | |
| Agpat2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 0.014 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.014 | |
| Trp53 | transformation related protein 53 | 0.014 | |
| Cd36 | CD36 antigen | 0.013 | |
| Lipe | lipase, hormone sensitive | 0.013 | |
| Lipa | lysosomal acid lipase A | 0.013 | |
| Adrb2 | adrenergic receptor, beta 2 | 0.013 | |
| Junb | Jun-B oncogene | 0.012 | |
| Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.012 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.011 | |
| Agtr2 | angiotensin II receptor, type 2 | 0.011 | |
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.010 | |
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.010 |