The network for 'regulation of gtp catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of gtp catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.

Mus musculus
Name Description Probability Func Analog Organism
Efnb2 ephrin B2 0.993
Epha4 Eph receptor A4 0.991
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.986
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.969
Arrb2 arrestin, beta 2 0.962
Rac1 RAS-related C3 botulinum substrate 1 0.960
Ntf3 neurotrophin 3 0.945
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.943
Ephb2 Eph receptor B2 0.940
Braf Braf transforming gene 0.928
Ccl2 chemokine (C-C motif) ligand 2 0.894
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.889
Plxnb1 plexin B1 0.873
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.870
Grb2 growth factor receptor bound protein 2 0.827
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.818
Bcl2 B-cell leukemia/lymphoma 2 0.800
Rictor RPTOR independent companion of MTOR, complex 2 0.794
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.784
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.777
Cbl Casitas B-lineage lymphoma 0.774
Bax BCL2-associated X protein 0.767
Plxna1 plexin A1 0.761
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.723
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.722
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.721
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.675
Dock1 dedicator of cytokinesis 1 0.672
Fgfr3 fibroblast growth factor receptor 3 0.648
Nf1 neurofibromatosis 1 0.647
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.641
Vav1 vav 1 oncogene 0.633
Rasgrp1 RAS guanyl releasing protein 1 0.631
Spry4 sprouty homolog 4 (Drosophila) 0.623
Selplg selectin, platelet (p-selectin) ligand 0.609
Plxnd1 plexin D1 0.607
Sox10 SRY-box containing gene 10 0.605
Ephb4 Eph receptor B4 0.580
Dlg4 discs, large homolog 4 (Drosophila) 0.569
Eps15 epidermal growth factor receptor pathway substrate 15 0.564
Mapkap1 mitogen-activated protein kinase associated protein 1 0.551
Lrrk2 leucine-rich repeat kinase 2 0.549
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.545
Spry2 sprouty homolog 2 (Drosophila) 0.532
Grin2d glutamate receptor, ionotropic, NMDA2D (epsilon 4) 0.524
Tsc1 tuberous sclerosis 1 0.523
Pxn paxillin 0.518
Git1 G protein-coupled receptor kinase-interactor 1 0.498
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.494
Src Rous sarcoma oncogene 0.492
Cdh6 cadherin 6 0.488
Drd2 dopamine receptor D2 0.480
Eea1 early endosome antigen 1 0.472
Kl klotho 0.468
Snx13 sorting nexin 13 0.460
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.460
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.454
Sbf2 SET binding factor 2 0.442
Akt1 thymoma viral proto-oncogene 1 0.442
Sh3bp1 SH3-domain binding protein 1 0.438
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.428
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.425
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.412
Hdac7 histone deacetylase 7 0.410
Hmha1 histocompatibility (minor) HA-1 0.409
Bcr breakpoint cluster region 0.408
Nf2 neurofibromatosis 2 0.406
Plxna3 plexin A3 0.401
Efnb1 ephrin B1 0.401
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.396
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.395
Mef2a myocyte enhancer factor 2A 0.394
Arhgap30 Rho GTPase activating protein 30 0.389
Wnt5a wingless-related MMTV integration site 5A 0.389
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.377
Plcg1 phospholipase C, gamma 1 0.375
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.369
Arrb1 arrestin, beta 1 0.369
Ilk integrin linked kinase 0.369
Mmp15 matrix metallopeptidase 15 0.367
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.360
Pdgfb platelet derived growth factor, B polypeptide 0.359
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.356
Grip1 glutamate receptor interacting protein 1 0.355
Pitpnm1 phosphatidylinositol transfer protein, membrane-associated 1 0.352
Rasgrp2 RAS, guanyl releasing protein 2 0.349
Dennd4b DENN/MADD domain containing 4B 0.348
Srgap2 SLIT-ROBO Rho GTPase activating protein 2 0.342
Obsl1 obscurin-like 1 0.342
Kcnk2 potassium channel, subfamily K, member 2 0.339
Sipa1 signal-induced proliferation associated gene 1 0.338
Myo18a myosin XVIIIA 0.331
Mtap2 microtubule-associated protein 2 0.330
Efna1 ephrin A1 0.329
Klf3 Kruppel-like factor 3 (basic) 0.328
Abr active BCR-related gene 0.327
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.323
Sh3bgrl SH3-binding domain glutamic acid-rich protein like 0.320
Sh3rf1 SH3 domain containing ring finger 1 0.316
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.314
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
CELE_F47G4.4 Protein F47G4.4 0.509
let-60 Protein LET-60 0.466
gpr-1 Protein GPR-1 0.316
bet-2 Protein BET-2 0.269
mpk-1 Protein MPK-1 0.262
sem-5 Protein SEM-5 0.233
rme-4 Protein RME-4 0.222
zfp-3 Protein ZFP-3 0.218
rpm-1 Protein RPM-1 0.211
lag-1 Protein LAG-1 0.208
eor-2 Protein EOR-2 0.180
snf-1 Protein SNF-1 0.172
cgef-1 Protein CGEF-1 0.160
sax-3 Protein SAX-3 0.151
goa-1 Protein GOA-1 0.143
zoo-1 Protein ZOO-1 0.140
sup-17 Protein SUP-17 0.138
atg-11 Protein ATG-11 0.132
egrh-1 Protein EGRH-1 0.123
tpxl-1 Protein TPXL-1 0.106
lin-45 Protein LIN-45 0.105
mrck-1 Protein MRCK-1 0.104
rgl-1 Protein RGL-1 0.101
fhod-1 Protein FHOD-1 0.100
sto-4 Protein STO-4 0.096
mbk-1 Protein MBK-1 0.094
gld-1 Protein GLD-1 0.093
CELE_W07A8.2 Protein W07A8.2 0.092
T04F8.6 Protein T04F8.6 0.088
sad-1 Protein SAD-1 0.088
afd-1 Protein AFD-1 0.085
rgs-6 Protein RGS-6 0.082
T28B11.1 Protein T28B11.1 0.080
sym-4 Protein SYM-4 0.080
CELE_T10D4.6 Protein T10D4.6 0.080
nrx-1 Protein NRX-1 0.080
rab-5 Protein RAB-5 0.079
pry-1 Protein PRY-1 0.077
chc-1 Protein CHC-1 0.072
F21A10.2 Protein F21A10.2 0.072
stau-1 Protein STAU-1 0.072
ptp-4 Protein PTP-4 0.071
pqn-39 Protein PQN-39 0.069
CELE_C46H3.2 Protein C46H3.2 0.069
egl-27 Protein EGL-27 0.068
tmc-2 Protein TMC-2 0.068
obr-3 Protein OBR-3 0.067
ric-8 Protein RIC-8 0.066
unc-26 Protein UNC-26 0.066
pat-3 Protein PAT-3 0.064
gly-7 Protein GLY-7 0.063
gpr-2 Protein GPR-2 0.062
par-6 Protein PAR-6 0.061
smp-1 Protein SMP-1 0.060
ced-6 Protein CED-6 0.060
nuo-3 Protein NUO-3 0.060
madf-5 Protein MADF-5 0.059
itr-1 Protein ITR-1 0.058
unc-79 Protein UNC-79 0.057
abl-1 Protein ABL-1 0.055
tbc-12 Protein TBC-12 0.054
lsm-6 Protein LSM-6 0.054
sav-1 Protein SAV-1 0.053
tat-1 Protein TAT-1 0.053
etr-1 Protein ETR-1 0.053
dpy-21 Protein DPY-21 0.052
daf-19 Protein DAF-19 0.051
F52G3.1 Protein F52G3.1 0.051
spdl-1 Protein SPDL-1 0.051
ddr-2 Protein DDR-2 0.050
ykt-6 Protein YKT-6 0.050
pdk-1 Protein PDK-1 0.049
F40F4.7 Protein F40F4.7 0.047
kal-1 Protein KAL-1 0.046
kin-25 Protein KIN-25 0.046
CELE_Y116A8C.26 Protein Y116A8C.26 0.045
hda-1 Protein HDA-1 0.045
dpf-3 Protein DPF-3 0.045
gei-8 Protein GEI-8 0.044
ZC477.5 Protein ZC477.5 0.044
C46C11.1 Protein C46C11.1 0.044
ced-10 Protein CED-10 0.043
R10E12.2 Protein R10E12.2 0.043
plk-1 Protein PLK-1 0.041
egl-36 Protein EGL-36 0.041
frm-7 Protein FRM-7 0.041
nhr-6 Protein NHR-6 0.040
zyg-9 Protein ZYG-9 0.040
F22D3.2 Protein F22D3.2 0.040
dnj-27 Protein DNJ-27 0.040
mig-22 Protein MIG-22 0.040
zfp-1 Protein ZFP-1 0.040
unc-53 Protein UNC-53 0.040
C11E4.6 Protein C11E4.6 0.040
nra-1 Protein NRA-1 0.038
nhl-3 Protein NHL-3 0.038
lst-4 Protein LST-4 0.037
tag-298 Protein TAG-298 0.037
gar-3 Protein GAR-3 0.037
ehs-1 Protein EHS-1 0.036
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Danio rerio
Name Description Probability Func Analog Organism
cnn2 calponin 2 0.480
nf1a neurofibromin 1a 0.398
plxnb2a plexin b2a 0.388
bida BH3 interacting domain death agonist 0.343
mcl1b myeloid cell leukemia sequence 1b 0.315
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.288
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.253
adrb2a adrenergic receptor, beta 2a 0.217
stc1l stanniocalcin 1, like 0.205
zbtb4 zinc finger and BTB domain containing 4 0.198
msna moesin a 0.197
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.191
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.190
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.182
tpm4 tropomyosin 4 0.177
icn ictacalcin 0.169
baxa bcl2-associated X protein, a 0.163
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.163
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.163
eprs glutamyl-prolyl-tRNA synthetase 0.161
mcl1a myeloid cell leukemia sequence 1a 0.161
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.159
optc opticin 0.155
rtcd1 RNA terminal phosphate cyclase domain 1 0.154
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.144
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.144
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.139
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.139
bcl2 B-cell leukemia/lymphoma 2 0.139
zgc:56466 zgc:56466 0.137
bactin1 bactin1 0.136
si:ch211-232m7.1 si:ch211-232m7.1 0.134
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.133
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.133
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.131
zgc:77517 zgc:77517 0.127
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.124
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.118
cpe carboxypeptidase E 0.118
zgc:56085 zgc:56085 0.115
gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b 0.113
nf1b neurofibromin 1b 0.110
ampd3 adenosine monophosphate deaminase 3 0.110
anxa2a annexin A2a 0.109
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.106
zgc:56548 zgc:56548 0.105
zgc:77752 zgc:77752 0.105
gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.103
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.102
tm9sf2 transmembrane 9 superfamily member 2 0.100
pparg peroxisome proliferator activated receptor gamma 0.099
pvrl1b poliovirus receptor-related 1b 0.099
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.097
slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.096
zeb1 zinc finger E-box binding homeobox 1 0.096
psen1 presenilin 1 0.095
cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 0.094
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.094
zgc:114181 zgc:114181 0.092
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.092
s100v2 S100 calcium binding protein V2 0.092
st8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.092
vmp1 vacuole membrane protein 1 0.091
zfyve26 zinc finger, FYVE domain containing 26 0.091
gna14 guanine nucleotide binding protein (G protein), alpha 14 0.090
ephb4b eph receptor B4b 0.090
lingo1b leucine rich repeat and Ig domain containing 1b 0.090
s100a10a S100 calcium binding protein A10a 0.089
ttyh2l tweety homolog 2, like 0.088
ncor1 nuclear receptor co-repressor 1 0.087
gng12a guanine nucleotide binding protein (G protein), gamma 12a 0.087
zgc:92392 zgc:92392 0.087
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.087
gro2 groucho 2 0.085
rcv1 recoverin 0.083
dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.083
cfl2l cofilin 2, like 0.082
pak2a p21 (CDKN1A)-activated kinase 2a 0.082
dusp6 dual specificity phosphatase 6 0.081
gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.081
acvr1b activin A receptor, type IB 0.081
gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 0.081
arpc5a actin related protein 2/3 complex, subunit 5A 0.081
vasp vasodilator-stimulated phosphoprotein 0.080
tuba1l tubulin, alpha 1, like 0.080
hs3st1l2 heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2 0.079
elovl4b elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b 0.079
wu:fc24e06 wu:fc24e06 0.078
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.078
acsl4a acyl-CoA synthetase long-chain family member 4a 0.078
depdc1a DEP domain containing 1a 0.077
rap2c RAP2C, member of RAS oncogene family 0.076
prom1a prominin 1a 0.075
LOC565839 tumor necrosis factor alpha-induced protein 2-like 0.074
ptprn2l protein tyrosine phosphatase, receptor type, N polypeptide 2, like 0.074
rock2a rho-associated, coiled-coil containing protein kinase 2a 0.074
dclk2 doublecortin-like kinase 2 0.074
si:dkey-228g21.4 si:dkey-228g21.4 0.073
nek7 NIMA (never in mitosis gene a)-related kinase 7 0.072
rrm2 ribonucleotide reductase M2 polypeptide 0.072
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.895
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.688
lgs legless 0.605
CG8155 CG8155 gene product from transcript CG8155-RA 0.567
plexB plexin B 0.484
Pkn Protein kinase related to protein kinase N 0.452
trio CG18214 gene product from transcript CG18214-RA 0.393
Wnk CG7177 gene product from transcript CG7177-RA 0.276
Smox Smad on X 0.266
CG6509 CG6509 gene product from transcript CG6509-RB 0.265
stg string 0.258
Khc Kinesin heavy chain 0.250
Galpha49B G protein alpha49B 0.235
Vps35 Vacuolar protein sorting 35 0.230
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.213
Tre1 trapped in endoderm-1 0.208
Stat92E Signal-transducer and activator of transcription protein at 92E 0.207
synj synaptojanin 0.203
cenG1A centaurin gamma 1A 0.196
Jra Jun-related antigen 0.178
Wnt5 Wnt oncogene analog 5 0.173
pod1 CG4532 gene product from transcript CG4532-RF 0.159
mbt mushroom bodies tiny 0.153
Dap160 Dynamin associated protein 160 0.153
stai stathmin 0.151
N Notch 0.144
insc inscuteable 0.141
Smg1 CG32743 gene product from transcript CG32743-RA 0.140
puc puckered 0.133
Rheb CG1081 gene product from transcript CG1081-RA 0.126
Pten CG5671 gene product from transcript CG5671-RB 0.124
ninaC neither inactivation nor afterpotential C 0.116
Git CG16728 gene product from transcript CG16728-RA 0.114
dnc dunce 0.114
CG17233 CG17233 gene product from transcript CG17233-RA 0.109
pyd polychaetoid 0.108
cno canoe 0.107
rok Rho-kinase 0.106
Myo31DF Myosin 31DF 0.106
Prp31 CG6876 gene product from transcript CG6876-RA 0.103
Pli Pellino 0.103
flw flapwing 0.100
gek genghis khan 0.099
NaCP60E Na channel protein 60E 0.096
Pk61C Protein kinase 61C 0.095
ari-2 ariadne 2 0.090
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.089
cta concertina 0.086
raps rapsynoid 0.085
l(2)k16918 lethal (2) k16918 0.084
Hem HEM-protein 0.084
L Lobe 0.083
Vps45 Vacuolar protein sorting 45 0.079
Fak56D Focal Adhesion Kinase 0.079
G-ialpha65A G protein alphai subunit 65A 0.078
CalpB Calpain-B 0.078
baz bazooka 0.078
mub mushroom-body expressed 0.077
Hr96 Hormone receptor-like in 96 0.077
Tsc1 CG6147 gene product from transcript CG6147-RA 0.076
yata CG1973 gene product from transcript CG1973-RA 0.074
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.073
cher cheerio 0.073
Spn Spinophilin 0.072
CG7158 CG7158 gene product from transcript CG7158-RA 0.072
p120ctn Adherens junction protein p120 0.072
Plc21C Phospholipase C at 21C 0.071
Sos Son of sevenless 0.069
su(s) suppressor of sable 0.068
Apc APC-like 0.067
klg klingon 0.065
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.064
Hph HIF prolyl hydroxylase 0.059
dos daughter of sevenless 0.059
trp transient receptor potential 0.059
Su(H) Suppressor of Hairless 0.058
CG8334 CG8334 gene product from transcript CG8334-RA 0.058
Sbf SET domain binding factor 0.058
kuz kuzbanian 0.057
Pld Phospholipase D 0.056
neur neuralized 0.055
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.055
Dab Disabled 0.055
tmod tropomodulin 0.054
Tor Target of rapamycin 0.054
rdgB retinal degeneration B 0.054
mago mago nashi 0.054
CG11033 CG11033 gene product from transcript CG11033-RB 0.053
siz schizo 0.052
CG32772 CG32772 gene product from transcript CG32772-RC 0.052
egl egalitarian 0.052
Rme-8 Receptor mediated endocytosis 8 0.051
neuroligin CG13772 gene product from transcript CG13772-RA 0.050
CG12766 CG12766 gene product from transcript CG12766-RA 0.048
Fs Follistatin 0.048
phl pole hole 0.048
Mad Mothers against dpp 0.047
UBL3 CG9038 gene product from transcript CG9038-RC 0.047
Ephrin CG1862 gene product from transcript CG1862-RA 0.047
Hnf4 Hepatocyte nuclear factor 4 0.047
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
EGFR epidermal growth factor receptor 1.000
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.999
PTK2 PTK2 protein tyrosine kinase 2 0.998
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.996
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.992
EXOSC3 exosome component 3 0.991
BCAR1 breast cancer anti-estrogen resistance 1 0.989
RHOA ras homolog gene family, member A 0.988
GRB7 growth factor receptor-bound protein 7 0.979
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.977
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.977
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.974
SFN stratifin 0.957
SH3KBP1 SH3-domain kinase binding protein 1 0.952
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.948
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.939
TSC2 tuberous sclerosis 2 0.933
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.930
RIN3 Ras and Rab interactor 3 0.926
S100A8 S100 calcium binding protein A8 0.923
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.918
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.910
S100A6 S100 calcium binding protein A6 0.908
DNM1 dynamin 1 0.904
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.901
DOCK1 dedicator of cytokinesis 1 0.897
S100B S100 calcium binding protein B 0.893
DNM2 dynamin 2 0.893
TSC1 tuberous sclerosis 1 0.890
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.876
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.871
JUN jun proto-oncogene 0.862
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.859
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.857
ADRBK1 adrenergic, beta, receptor kinase 1 0.828
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.825
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.823
TBCD tubulin folding cofactor D 0.822
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.821
FASLG Fas ligand (TNF superfamily, member 6) 0.816
FOS FBJ murine osteosarcoma viral oncogene homolog 0.805
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.793
GAB1 GRB2-associated binding protein 1 0.784
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.777
TNK2 tyrosine kinase, non-receptor, 2 0.777
FMNL1 formin-like 1 0.775
MPDZ multiple PDZ domain protein 0.767
RGS2 regulator of G-protein signaling 2, 24kDa 0.747
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.742
S100A11 S100 calcium binding protein A11 0.728
SH3RF1 SH3 domain containing ring finger 1 0.727
NCK2 NCK adaptor protein 2 0.722
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.715
PLCG1 phospholipase C, gamma 1 0.711
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.708
S100A9 S100 calcium binding protein A9 0.708
NCKAP1 NCK-associated protein 1 0.694
CCR5 chemokine (C-C motif) receptor 5 0.690
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.688
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.668
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.666
S100A1 S100 calcium binding protein A1 0.651
BBS10 Bardet-Biedl syndrome 10 0.647
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.637
SH3BP2 SH3-domain binding protein 2 0.626
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.616
PKN3 protein kinase N3 0.612
ARL3 ADP-ribosylation factor-like 3 0.610
CYTH4 cytohesin 4 0.608
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.604
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.602
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.597
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.595
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.588
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.585
S100A4 S100 calcium binding protein A4 0.573
EPHA7 EPH receptor A7 0.570
PKN2 protein kinase N2 0.553
CCL4 chemokine (C-C motif) ligand 4 0.549
GSK3B glycogen synthase kinase 3 beta 0.537
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.523
MYCBP2 MYC binding protein 2 0.523
MPRIP myosin phosphatase Rho interacting protein 0.519
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.506
UNC119 unc-119 homolog (C. elegans) 0.504
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.501
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.495
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.493
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.485
MARK3 MAP/microtubule affinity-regulating kinase 3 0.484
CAPG capping protein (actin filament), gelsolin-like 0.477
ANKRD28 ankyrin repeat domain 28 0.471
TJP2 tight junction protein 2 (zona occludens 2) 0.464
FNBP1 formin binding protein 1 0.459
RHOC ras homolog gene family, member C 0.456
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 0.455
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.454
PLXND1 plexin D1 0.453
BCL2L1 BCL2-like 1 0.452
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Sstr1 somatostatin receptor 1 0.067
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.067
Rap1b RAP1B, member of RAS oncogene family 0.058
Svop SV2 related protein 0.049
Sdc3 syndecan 3 0.047
Cngb1 cyclic nucleotide gated channel beta 1 0.043
Mospd2 motile sperm domain containing 2 0.041
Anxa2 annexin A2 0.040
Gria2 glutamate receptor, ionotropic, AMPA 2 0.040
Pja2 praja 2, RING-H2 motif containing 0.037
Homer1 homer homolog 1 (Drosophila) 0.036
Amph amphiphysin 0.036
Epas1 endothelial PAS domain protein 1 0.033
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.032
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.032
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.030
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.030
Copb1 coatomer protein complex, subunit beta 1 0.030
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.029
Adora1 adenosine A1 receptor 0.029
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.029
Tgfbr2 transforming growth factor, beta receptor II 0.029
Adcy6 adenylate cyclase 6 0.029
Hand2 heart and neural crest derivatives expressed 2 0.028
Prkch protein kinase C, eta 0.028
Dapk3 death-associated protein kinase 3 0.028
Sbf1 SET binding factor 1 0.027
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.027
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.026
Arpc3 actin related protein 2/3 complex, subunit 3 0.025
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.025
Fmnl1 formin-like 1 0.025
Syap1 synapse associated protein 1 0.024
Nptn neuroplastin 0.024
Sec1 secretory blood group 1 0.024
Shank2 SH3 and multiple ankyrin repeat domains 2 0.024
Abcf3 ATP-binding cassette, subfamily F (GCN20), member 3 0.024
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.024
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.024
Sept10 septin 10 0.024
Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 0.023
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.023
Map2 microtubule-associated protein 2 0.023
Scn8a sodium channel, voltage gated, type VIII, alpha subunit 0.023
Stx2 syntaxin 2 0.023
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.023
Fgfr1 Fibroblast growth factor receptor 1 0.023
Prdm2 PR domain containing 2, with ZNF domain 0.023
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.023
A4galt alpha 1,4-galactosyltransferase 0.023
Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 0.023
Scn3b sodium channel, voltage-gated, type III, beta 0.022
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.022
Snap25 synaptosomal-associated protein 25 0.022
Robo2 roundabout homolog 2 (Drosophila) 0.022
Adrbk1 adrenergic, beta, receptor kinase 1 0.022
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.021
Syn1 synapsin I 0.021
Lphn2 latrophilin 2 0.021
Cfp complement factor properdin 0.021
Lpcat4 lysophosphatidylcholine acyltransferase 4 0.021
Ap2a2 adaptor-related protein complex 2, alpha 2 subunit 0.021
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.021
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.020
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.020
Prkcb protein kinase C, beta 0.020
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.020
Drd1a dopamine receptor D1A 0.020
Klf6 Kruppel-like factor 6 0.020
LOC313672 kazrin 0.020
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.020
Nckap1 NCK-associated protein 1 0.020
Braf v-raf murine sarcoma viral oncogene homolog B1 0.020
Cap2 CAP, adenylate cyclase-associated protein, 2 (yeast) 0.020
Ryr2 ryanodine receptor 2, cardiac 0.020
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.019
Rara retinoic acid receptor, alpha 0.019
Itgb2 integrin, beta 2 0.019
Dnm1 dynamin 1 0.019
Mapk10 mitogen activated protein kinase 10 0.019
Tmem151a transmembrane protein 151A 0.019
Plcd1 phospholipase C, delta 1 0.019
Fgfr2 fibroblast growth factor receptor 2 0.019
Ptgfrn prostaglandin F2 receptor negative regulator 0.019
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.018
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.018
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.018
Nck1 NCK adaptor protein 1 0.018
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.018
Prrx1 paired related homeobox 1 0.018
Tek TEK tyrosine kinase, endothelial 0.018
Vamp3 vesicle-associated membrane protein 3 0.018
Fam108a1 family with sequence similarity 108, member A1 0.018
Akap12 A kinase (PRKA) anchor protein 12 0.018
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.018
Camk4 calcium/calmodulin-dependent protein kinase IV 0.018
Plekha6 pleckstrin homology domain containing, family A member 6 0.018
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.018
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.018
Zfp260 zinc finger protein 260 0.018
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GYL1 Gyl1p 0.531
STE5 Ste5p 0.505
STE11 Ste11p 0.404
RHO1 Rho1p 0.284
GCD6 Gcd6p 0.281
ROM2 Rom2p 0.214
AVO1 Avo1p 0.204
SUI3 Sui3p 0.189
IRA1 Ira1p 0.184
MKK1 Mkk1p 0.179
TRS65 Trs65p 0.177
SPA2 Spa2p 0.165
PKC1 Pkc1p 0.157
GCD7 Gcd7p 0.146
KOG1 Kog1p 0.128
GCD11 Gcd11p 0.122
VPS15 Vps15p 0.115
CDC24 Cdc24p 0.110
GDI1 Gdi1p 0.109
TPK3 Tpk3p 0.090
SUI2 Sui2p 0.090
FKH1 Fkh1p 0.083
STE4 Ste4p 0.081
BEM3 Bem3p 0.080
SEC16 Sec16p 0.080
GLO3 Glo3p 0.073
SAC7 Sac7p 0.073
SRP54 Srp54p 0.072
YPT53 Ypt53p 0.072
RFC1 Rfc1p 0.069
TSC11 Tsc11p 0.067
MNN9 Mnn9p 0.067
MDS3 Mds3p 0.067
FYV8 Fyv8p 0.066
FMS1 Fms1p 0.063
YPT52 Ypt52p 0.061
NUP85 Nup85p 0.058
SLG1 Slg1p 0.057
GPA1 Gpa1p 0.057
GIC2 Gic2p 0.056
GPB2 Gpb2p 0.056
GCD1 Gcd1p 0.053
TOM1 Tom1p 0.050
PPE1 Ppe1p 0.049
YHR127W hypothetical protein 0.049
VPS74 Vps74p 0.048
CYK3 Cyk3p 0.048
CCT4 Cct4p 0.047
STT4 Stt4p 0.047
VPS41 Vps41p 0.046
BST1 Bst1p 0.045
FUS1 Fus1p 0.044
YOL087C hypothetical protein 0.044
YPR148C hypothetical protein 0.044
CCT2 Cct2p 0.044
ARP10 Arp10p 0.043
NEO1 Neo1p 0.043
HSV2 Hsv2p 0.042
FAA2 Faa2p 0.042
PRS2 Prs2p 0.042
MRS6 Mrs6p 0.041
GDS1 Gds1p 0.040
STE2 Ste2p 0.040
INP53 Inp53p 0.040
FUS2 Fus2p 0.040
TRS31 Trs31p 0.040
TOR1 Tor1p 0.040
TRS85 Trs85p 0.039
PTP2 Ptp2p 0.039
TCO89 Tco89p 0.039
YDR186C hypothetical protein 0.038
ATG20 Atg20p 0.038
ERV25 Erv25p 0.037
YIP3 Yip3p 0.037
YNL108C hypothetical protein 0.036
FAR1 Far1p 0.035
PPH21 Pph21p 0.035
PPX1 Ppx1p 0.035
PEP5 Pep5p 0.035
APM3 Apm3p 0.035
MSB3 Msb3p 0.034
YML131W hypothetical protein 0.034
USO1 Uso1p 0.034
RPN14 Rpn14p 0.034
RGA1 Rga1p 0.033
SEC53 Sec53p 0.033
URA3 Ura3p 0.033
TUS1 Tus1p 0.033
STB2 Stb2p 0.033
LEM3 Lem3p 0.032
NAT1 Nat1p 0.032
CCH1 Cch1p 0.031
URA6 Ura6p 0.031
RRI1 Rri1p 0.031
YIR035C hypothetical protein 0.031
NCE103 Nce103p 0.031
SVF1 Svf1p 0.030
BRN1 Brn1p 0.029
COS111 Cos111p 0.029
FAR11 Far11p 0.029