The network for 'carbohydrate biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

carbohydrate biosynthetic process

The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

Name Description Probability Func Analog Organism
Insr insulin receptor 0.998
Lepr leptin receptor 0.981
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.953
Esr1 estrogen receptor 1 (alpha) 0.948
Irs2 insulin receptor substrate 2 0.920
Lep leptin 0.898
Prlr prolactin receptor 0.858
Cry2 cryptochrome 2 (photolyase-like) 0.785
Per2 period homolog 2 (Drosophila) 0.783
Igf1r insulin-like growth factor I receptor 0.732
Pax8 paired box gene 8 0.622
Tgfb1 transforming growth factor, beta 1 0.611
Egr1 early growth response 1 0.600
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.598
Drd2 dopamine receptor D2 0.588
C1qa complement component 1, q subcomponent, alpha polypeptide 0.586
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.582
Ulk1 Unc-51 like kinase 1 (C. elegans) 0.577
Mup5 major urinary protein 5 0.537
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.529
Clock circadian locomotor output cycles kaput 0.515
Thra thyroid hormone receptor alpha 0.468
Clk4 CDC like kinase 4 0.430
Socs1 suppressor of cytokine signaling 1 0.429
Cidec cell death-inducing DFFA-like effector c 0.426
Pim3 proviral integration site 3 0.408
Aldoa aldolase A, fructose-bisphosphate 0.406
Pim1 proviral integration site 1 0.401
Grb10 growth factor receptor bound protein 10 0.400
Stat5a signal transducer and activator of transcription 5A 0.359
Mup4 major urinary protein 4 0.351
Slc12a1 solute carrier family 12, member 1 0.337
Mark4 MAP/microtubule affinity-regulating kinase 4 0.336
Pgam1 phosphoglycerate mutase 1 0.333
Lipe lipase, hormone sensitive 0.314
Per1 period homolog 1 (Drosophila) 0.312
Ar androgen receptor 0.308
Pax2 paired box gene 2 0.306
Thrb thyroid hormone receptor beta 0.302
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.300
Agtr1a angiotensin II receptor, type 1a 0.299
Akt1 thymoma viral proto-oncogene 1 0.298
Mup10 major urinary protein 10 0.297
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.286
Ghr growth hormone receptor 0.277
Ccnl2 cyclin L2 0.272
Rxrg retinoid X receptor gamma 0.267
Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A 0.264
Ctnnb1 catenin (cadherin associated protein), beta 1 0.262
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.256
Kiss1 KiSS-1 metastasis-suppressor 0.255
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.255
Usp2 ubiquitin specific peptidase 2 0.244
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.243
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.242
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.236
Fgfr1 fibroblast growth factor receptor 1 0.235
Cfd complement factor D (adipsin) 0.234
Tef thyrotroph embryonic factor 0.233
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.231
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.230
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.223
Egfr epidermal growth factor receptor 0.219
Trib3 tribbles homolog 3 (Drosophila) 0.219
Ldha lactate dehydrogenase A 0.215
Pparg peroxisome proliferator activated receptor gamma 0.210
Pgk1 phosphoglycerate kinase 1 0.208
Csf1r colony stimulating factor 1 receptor 0.205
Nos1 nitric oxide synthase 1, neuronal 0.203
Pcx pyruvate carboxylase 0.198
Vdr vitamin D receptor 0.193
Mup19 major urinary protein 19 0.188
Fbxl3 F-box and leucine-rich repeat protein 3 0.186
Mup12 major urinary protein 12 0.184
Tcf7 transcription factor 7, T-cell specific 0.184
Pnpla2 patatin-like phospholipase domain containing 2 0.184
Rxra retinoid X receptor alpha 0.180
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.174
Adig adipogenin 0.174
Clk1 CDC-like kinase 1 0.174
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.170
Pim2 proviral integration site 2 0.169
Mup9 major urinary protein 9 0.169
Serpina3c serine (or cysteine) peptidase inhibitor, clade A, member 3C 0.168
Lef1 lymphoid enhancer binding factor 1 0.167
Mup1 major urinary protein 1 0.166
Apoc4 apolipoprotein C-IV 0.164
Jun Jun oncogene 0.162
D4Wsu53e DNA segment, Chr 4, Wayne State University 53, expressed 0.159
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.158
Timp1 tissue inhibitor of metalloproteinase 1 0.150
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.148
Mup3 major urinary protein 3 0.145
Thrsp thyroid hormone responsive SPOT14 homolog (Rattus) 0.144
Stat5b signal transducer and activator of transcription 5B 0.144
C1qc complement component 1, q subcomponent, C chain 0.143
Ren1 renin 1 structural 0.141
Htt huntingtin 0.140
Ppara peroxisome proliferator activated receptor alpha 0.138
Dbp D site albumin promoter binding protein 0.138
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
bus-18 Protein BUS-18 0.044
T07D3.4 Protein T07D3.4 0.031
bus-4 Protein BUS-4 0.028
pkg-1 Protein PKG-1 0.027
mlk-1 Protein MLK-1 0.027
sek-1 Protein SEK-1 0.027
smp-1 Protein SMP-1 0.025
Y119C1A.1 Protein Y119C1A.1 0.025
ksr-1 Protein KSR-1 0.023
sas-4 Protein SAS-4 0.022
skn-1 Protein SKN-1 0.022
lpin-1 Protein LPIN-1 0.022
daf-1 Protein DAF-1 0.021
K10D6.4 Protein K10D6.4 0.021
CELE_Y75B8A.14 Protein Y75B8A.14 0.021
F13D2.1 Protein F13D2.1 0.021
nhr-49 Protein NHR-49 0.020
amph-1 Protein AMPH-1 0.020
glf-1 Protein GLF-1 0.020
sec-6 Protein SEC-6 0.019
daf-4 Protein DAF-4 0.019
C34D10.2 Protein C34D10.2 0.019
bus-12 Protein BUS-12 0.018
nhr-69 Protein NHR-69 0.018
daf-15 Protein DAF-15 0.018
tag-147 Protein TAG-147 0.018
fem-1 Protein FEM-1 0.017
vps-33.1 Protein VPS-33.1 0.017
pmp-3 Protein PMP-3 0.017
vps-35 Protein VPS-35 0.017
T28C6.7 Protein T28C6.7 0.017
F53F10.2 Protein F53F10.2 0.017
sph-1 Protein SPH-1 0.017
pnk-1 Protein PNK-1 0.016
daf-11 Protein DAF-11 0.016
rpn-1 Protein RPN-1 0.016
smg-4 Protein SMG-4 0.016
CELE_C01B10.10 Protein C01B10.10 0.016
daf-16 Protein DAF-16 0.016
CELE_W10G11.19 Protein W10G11.19 0.016
msp-63 Protein MSP-63 0.016
bre-3 Protein BRE-3 0.015
ZK265.9 Protein ZK265.9 0.015
C48A7.2 Protein C48A7.2 0.015
R31.2 Protein R31.2 0.015
bus-19 Protein BUS-19 0.015
K06H7.2 Protein K06H7.2 0.015
srf-3 Protein SRF-3 0.015
goa-1 Protein GOA-1 0.015
F25E2.3 Protein F25E2.3 0.015
pal-1 Protein PAL-1 0.015
ehbp-1 Protein EHBP-1 0.014
ZC410.5 Protein ZC410.5 0.014
hsp-1 Protein HSP-1 0.014
K10B3.5 Protein K10B3.5 0.014
dpm-1 Protein DPM-1 0.014
pas-7 Protein PAS-7 0.014
unc-11 Protein UNC-11 0.014
ceh-44 Protein CEH-44 0.014
nhr-40 Protein NHR-40 0.014
F55C12.5 Protein F55C12.5 0.014
nhr-20 Protein NHR-20 0.014
clr-1 Protein CLR-1 0.014
akt-2 Protein AKT-2 0.014
apr-1 Protein APR-1 0.013
bam-2 Protein BAM-2 0.013
unc-94 Protein UNC-94 0.013
pck-2 Protein PCK-2 0.013
pup-2 Protein PUP-2 0.013
Y73B6BL.4 Protein Y73B6BL.4 0.013
gla-3 Protein GLA-3 0.013
bre-2 Protein BRE-2 0.013
gsp-1 Protein GSP-1 0.013
T13C2.6 Protein T13C2.6 0.013
F48E8.6 Protein F48E8.6 0.013
Y25C1A.7 Protein Y25C1A.7 0.013
rpl-7A Protein RPL-7A 0.013
mab-5 Protein MAB-5 0.013
pry-1 Protein PRY-1 0.013
imp-3 Protein IMP-3 0.013
C18B12.4 Protein C18B12.4 0.013
C33A11.1 Protein C33A11.1 0.013
pbs-4 Protein PBS-4 0.013
pam-1 Protein PAM-1 0.013
lsy-12 Protein LSY-12 0.013
vab-1 Protein VAB-1 0.012
ung-1 Protein UNG-1 0.012
CELE_F59B2.2 Protein F59B2.2 0.012
ran-2 Protein RAN-2 0.012
pab-2 Protein PAB-2 0.012
csnk-1 Protein CSNK-1 0.012
rgs-2 Protein RGS-2 0.012
nhr-64 Protein NHR-64 0.012
spat-2 Protein SPAT-2 0.012
vps-41 Protein VPS-41 0.012
sqv-8 Protein SQV-8 0.012
farl-11 Protein FARL-11 0.012
T27A3.7 Protein T27A3.7 0.012
CELE_F28H1.1 Protein F28H1.1 0.012
daf-5 Protein DAF-5 0.012
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
rxrbb retinoid x receptor, beta b 0.240
pkm2a pyruvate kinase, muscle, a 0.154
pgk1 phosphoglycerate kinase 1 0.143
mfn2 mitofusin 2 0.141
zgc:64133 zgc:64133 0.130
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.122
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.102
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.100
ptprk protein tyrosine phosphatase, receptor type, K 0.097
cyp1d1 cytochrome P450, family 1, subfamily D, polypeptide 1 0.096
zgc:56466 zgc:56466 0.095
slc35b2 solute carrier family 35, member B2 0.095
sox5 SRY-box containing gene 5 0.094
zgc:56306 zgc:56306 0.093
zgc:162270 zgc:162270 0.091
adipor2 adiponectin receptor 2 0.089
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.085
clk4a CDC-like kinase 4a 0.080
bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide 0.075
mst1 macrophage stimulating 1 (hepatocyte growth factor-like) 0.074
lpp LIM domain containing preferred translocation partner in lipoma 0.074
zgc:112986 zgc:112986 0.072
gle1 GLE1 RNA export mediator homolog (yeast) 0.071
xylt1 xylosyltransferase 1 0.071
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.070
sh3gl1b SH3-domain GRB2-like 1b 0.070
wsb1 WD repeat and SOCS box-containing 1 0.070
ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2 0.067
itgb1b integrin, beta 1b 0.067
cga glycoprotein hormones, alpha polypeptide 0.067
junb jun B proto-oncogene 0.067
aldocb aldolase C, fructose-bisphosphate, b 0.067
gatsl2 GATS protein-like 2 0.066
dsg2 desmoglein 2 0.061
si:rp71-39b20.7 si:rp71-39b20.7 0.060
cpn1 carboxypeptidase N, polypeptide 1 0.058
hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 0.057
ier5 immediate early response 5 0.056
hlxb9la homeo box HB9 like a 0.056
cyp1a cytochrome P450, family 1, subfamily A 0.055
adipor1a adiponectin receptor 1a 0.055
gpt2l glutamic pyruvate transaminase (alanine aminotransferase) 2, like 0.055
slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 0.054
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.054
hgd homogentisate 1,2-dioxygenase 0.053
vwf von Willebrand factor 0.053
dusp4 dual specificity phosphatase 4 0.053
foxi3b forkhead box I3b 0.052
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.052
aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.052
cand1 cullin-associated and neddylation-dissociated 1 0.051
gpx4a glutathione peroxidase 4a 0.051
pah phenylalanine hydroxylase 0.050
pc pyruvate carboxylase 0.049
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.048
lama2 laminin, alpha 2 0.048
ecm2 extracellular matrix protein 2, female organ and adipocyte specific 0.048
cry2a cryptochrome 2a 0.048
sdc2 syndecan 2 0.048
fbp1b fructose-1,6-bisphosphatase 1b 0.048
hdac9b histone deacetylase 9b 0.047
sb:eu697 sb:eu697 0.047
dio1 deiodinase, iodothyronine, type I 0.047
pkp3 plakophilin 3 0.046
irf2bp1 interferon regulatory factor 2 binding protein 1 0.046
si:ch211-102c2.6 si:ch211-102c2.6 0.045
sepp1b selenoprotein P, plasma, 1b 0.045
slc38a4 solute carrier family 38, member 4 0.045
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.044
znf346 zinc finger protein 346 0.044
ripk2 receptor-interacting serine-threonine kinase 2 0.044
ldhba lactate dehydrogenase Ba 0.044
smad3a MAD homolog 3a (Drosophila) 0.043
fah fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.043
cpeb4 cytoplasmic polyadenylation element binding protein 4 0.043
adm2 adrenomedullin 2 0.042
dpf2l D4, zinc and double PHD fingers family 2, like 0.042
siah2l seven in absentia homolog 2 (Drosophila)-like 0.042
pgm1 phosphoglucomutase 1 0.042
ahr1a aryl hydrocarbon receptor 1a 0.041
plxnb2a plexin b2a 0.041
slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 0.041
rbm39a RNA binding motif protein 39a 0.041
slc25a25a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a 0.041
si:dkey-258f14.5 si:dkey-258f14.5 0.040
cnih cornichon homolog (Drosophila) 0.040
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.040
akirin1 akirin 1 0.040
cyfip2 cytoplasmic FMR1 interacting protein 2 0.040
foxa3 forkhead box A3 0.040
acadl acyl-Coenzyme A dehydrogenase, long chain 0.040
LOC100330224 fatty acid binding protein 1b-like 0.039
tbeta-a beta thymosin-like protein 2 0.039
LOC556764 similar to Probable RNA-dependent helicase p72 (DEAD-box protein p72) (DEAD-box protein 17) 0.038
eif1b eukaryotic translation initiation factor 1B 0.038
pygmb phosphorylase, glycogen (muscle) b 0.038
cldn15lb claudin 15-like b 0.038
pfn2l profilin 2 like 0.038
scp2 sterol carrier protein 2 0.037
otc ornithine carbamoyltransferase 0.037
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Gpdh Glycerol 3 phosphate dehydrogenase 0.549
GlyP Glycogen phosphorylase 0.447
Pgm Phosphogluconate mutase 0.399
Pgk Phosphoglycerate kinase 0.382
CG8036 CG8036 gene product from transcript CG8036-RB 0.296
Zw Zwischenferment 0.295
ttv tout-velu 0.287
Eno Enolase 0.261
botv brother of tout-velu 0.256
CG6904 CG6904 gene product from transcript CG6904-RC 0.221
Ext2 CG8433 gene product from transcript CG8433-RA 0.186
CG9485 CG9485 gene product from transcript CG9485-RD 0.167
ry rosy 0.161
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.125
Got2 Glutamate oxaloacetate transaminase 2 0.122
Trxr-1 Thioredoxin reductase-1 0.112
CG14568 CG14568 gene product from transcript CG14568-RA 0.109
Bre1 CG10542 gene product from transcript CG10542-RA 0.107
crol crooked legs 0.107
Adh Alcohol dehydrogenase 0.101
hipk homeodomain interacting protein kinase 0.092
CG7998 CG7998 gene product from transcript CG7998-RA 0.089
yip2 yippee interacting protein 2 0.067
Unc-76 CG3981 gene product from transcript CG3981-RB 0.061
Cyp4e2 Cytochrome P450-4e2 0.054
Thor CG8846 gene product from transcript CG8846-RA 0.049
foxo forkhead box, sub-group O 0.048
CG16926 CG16926 gene product from transcript CG16926-RA 0.047
egh egghead 0.047
Sara Smad anchor for receptor activation 0.045
Prat2 Phosphoribosylamidotransferase 2 0.040
Argk Arginine kinase 0.040
wls wntless 0.040
regucalcin CG1803 gene product from transcript CG1803-RA 0.039
capt capulet 0.039
CG30409 CG30409 gene product from transcript CG30409-RA 0.037
Gfat2 Glutamine:fructose-6-phosphate aminotransferase 2 0.037
CG31226 CG31226 gene product from transcript CG31226-RB 0.037
sgl sugarless 0.036
Actn alpha actinin 0.036
Lsd-1 Lipid storage droplet-1 0.036
fln flightin 0.035
Pgd Phosphogluconate dehydrogenase 0.035
Hn Henna 0.034
CG8446 CG8446 gene product from transcript CG8446-RC 0.033
smo smoothened 0.032
Mo25 CG4083 gene product from transcript CG4083-RA 0.030
CG11347 CG11347 gene product from transcript CG11347-RE 0.029
Vinc Vinculin 0.029
GstS1 Glutathione S transferase S1 0.028
fbp fructose-1,6-bisphosphatase 0.028
Akt1 CG4006 gene product from transcript CG4006-RA 0.028
CG5362 CG5362 gene product from transcript CG5362-RA 0.028
Thiolase CG4581 gene product from transcript CG4581-RA 0.027
Mlc2 Myosin light chain 2 0.027
Zyx102EF CG32018 gene product from transcript CG32018-RA 0.027
gus gustavus 0.027
CG6776 CG6776 gene product from transcript CG6776-RA 0.026
CG12030 CG12030 gene product from transcript CG12030-RA 0.026
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.025
Pgi Phosphoglucose isomerase 0.025
CG42672 CG42672 gene product from transcript CG42672-RD 0.025
Hex-A Hexokinase A 0.024
Socs36E Suppressor of cytokine signaling at 36E 0.023
Men Malic enzyme 0.023
Rab7 Rab-protein 7 0.023
CG3371 CG3371 gene product from transcript CG3371-RA 0.023
disp dispatched 0.023
elfless CG15150 gene product from transcript CG15150-RB 0.022
CG8668 CG8668 gene product from transcript CG8668-RA 0.022
Csat CG2675 gene product from transcript CG2675-RA 0.022
Deaf1 Deformed epidermal autoregulatory factor-1 0.022
CG31958 CG31958 gene product from transcript CG31958-RA 0.021
CG4332 CG4332 gene product from transcript CG4332-RA 0.021
Ras64B Ras oncogene at 64B 0.021
rnh1 ribonuclease H1 0.021
l(3)82Fd CG32464 gene product from transcript CG32464-RR 0.020
CG2528 CG2528 gene product from transcript CG2528-RB 0.020
CG3534 CG3534 gene product from transcript CG3534-RA 0.020
CG5171 CG5171 gene product from transcript CG5171-RC 0.020
UGP CG4347 gene product from transcript CG4347-RE 0.020
robl22E CG10838 gene product from transcript CG10838-RA 0.020
dbo diablo 0.019
CG4438 CG4438 gene product from transcript CG4438-RB 0.019
CG34172 CG34172 gene product from transcript CG34172-RA 0.019
Met Methoprene-tolerant 0.019
Pvr PDGF- and VEGF-receptor related 0.019
stumps CG31317 gene product from transcript CG31317-RC 0.018
mth methuselah 0.018
boi brother of iHog 0.018
heix heixuedian 0.018
retm real-time 0.018
whd withered 0.017
CG17598 CG17598 gene product from transcript CG17598-RA 0.017
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.017
CG10960 CG10960 gene product from transcript CG10960-RC 0.017
Cpr Cytochrome P450 reductase 0.017
CG7461 CG7461 gene product from transcript CG7461-RB 0.017
CG11594 CG11594 gene product from transcript CG11594-RB 0.016
mub mushroom-body expressed 0.016
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.995
INSR insulin receptor 0.989
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.807
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.718
AR androgen receptor 0.708
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.680
BCL3 B-cell CLL/lymphoma 3 0.670
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.662
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.650
ESR1 estrogen receptor 1 0.628
CREBBP CREB binding protein 0.619
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.586
NUMB numb homolog (Drosophila) 0.560
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.550
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.540
GRB10 growth factor receptor-bound protein 10 0.476
APP amyloid beta (A4) precursor protein 0.428
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.420
MAPT microtubule-associated protein tau 0.414
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.413
IGF1R insulin-like growth factor 1 receptor 0.405
IRS1 insulin receptor substrate 1 0.308
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.282
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.277
SIRT1 sirtuin 1 0.256
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.253
HIP1 huntingtin interacting protein 1 0.224
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.218
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.201
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.200
IRS2 insulin receptor substrate 2 0.191
GYS1 glycogen synthase 1 (muscle) 0.189
CREB1 cAMP responsive element binding protein 1 0.188
LZTS2 leucine zipper, putative tumor suppressor 2 0.153
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.146
HIPK2 homeodomain interacting protein kinase 2 0.146
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.145
BHLHE40 basic helix-loop-helix family, member e40 0.141
JUN jun proto-oncogene 0.139
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.134
PKM2 pyruvate kinase, muscle 0.128
RARA retinoic acid receptor, alpha 0.127
TADA3 transcriptional adaptor 3 0.126
TNIP2 TNFAIP3 interacting protein 2 0.122
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.121
EP300 E1A binding protein p300 0.116
ACACA acetyl-CoA carboxylase alpha 0.112
TTR transthyretin 0.110
BCAR1 breast cancer anti-estrogen resistance 1 0.110
LRRK2 leucine-rich repeat kinase 2 0.109
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.109
TRIB3 tribbles homolog 3 (Drosophila) 0.104
NCOA6 nuclear receptor coactivator 6 0.100
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.095
RXRA retinoid X receptor, alpha 0.095
HK1 hexokinase 1 0.094
NOXA1 NADPH oxidase activator 1 0.090
DDIT3 DNA-damage-inducible transcript 3 0.083
TALDO1 transaldolase 1 0.083
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.082
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.080
THBS1 thrombospondin 1 0.079
PRKCZ protein kinase C, zeta 0.074
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.074
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.073
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.073
GSK3B glycogen synthase kinase 3 beta 0.072
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.071
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.071
DOCK7 dedicator of cytokinesis 7 0.068
EGFR epidermal growth factor receptor 0.067
PPID peptidylprolyl isomerase D 0.066
AARS alanyl-tRNA synthetase 0.062
FOXO3 forkhead box O3 0.061
DCTN1 dynactin 1 0.059
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.059
TRRAP transformation/transcription domain-associated protein 0.057
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 0.056
MAP4 microtubule-associated protein 4 0.054
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.054
FUNDC2 FUN14 domain containing 2 0.053
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.053
NRP1 neuropilin 1 0.053
PICK1 protein interacting with PRKCA 1 0.053
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.052
PRKCA protein kinase C, alpha 0.052
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.052
ITGB1BP3 integrin beta 1 binding protein 3 0.051
APC adenomatous polyposis coli 0.051
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.050
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.049
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.048
MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0.048
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.048
PRKCB protein kinase C, beta 0.048
SESN2 sestrin 2 0.047
DCAF7 DDB1 and CUL4 associated factor 7 0.046
NCOA1 nuclear receptor coactivator 1 0.046
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.045
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.045
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Pkm2 pyruvate kinase, muscle 0.697
Gpi glucose phosphate isomerase 0.247
Tpi1 triosephosphate isomerase 1 0.241
Aldoa aldolase A, fructose-bisphosphate 0.182
Ldha lactate dehydrogenase A 0.168
Dbp D site of albumin promoter (albumin D-box) binding protein 0.161
Psmb5 proteasome (prosome, macropain) subunit, beta type 5 0.157
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.118
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.096
G6pc glucose-6-phosphatase, catalytic subunit 0.088
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.088
Pygm phosphorylase, glycogen, muscle 0.086
Pgam1 phosphoglycerate mutase 1 (brain) 0.077
Eno1 enolase 1, (alpha) 0.076
Igsf1 immunoglobulin superfamily, member 1 0.067
Ugp2 UDP-glucose pyrophosphorylase 2 0.066
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.061
Rxrg retinoid X receptor gamma 0.061
Pgk1 phosphoglycerate kinase 1 0.060
Eef2 eukaryotic translation elongation factor 2 0.049
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.048
Pgm1 phosphoglucomutase 1 0.043
Vipr1 vasoactive intestinal peptide receptor 1 0.043
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.043
Dio1 deiodinase, iodothyronine, type I 0.043
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.041
Etfdh electron-transferring-flavoprotein dehydrogenase 0.041
Ghr growth hormone receptor 0.037
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.036
Cacng1 calcium channel, voltage-dependent, gamma subunit 1 0.035
Ldhd lactate dehydrogenase D 0.035
Pfkm phosphofructokinase, muscle 0.033
Rab1b RAB1B, member RAS oncogene family 0.033
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.033
Flt1 FMS-related tyrosine kinase 1 0.032
Phkg1 phosphorylase kinase, gamma 1 0.032
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.031
Mef2d myocyte enhancer factor 2D 0.030
Obp3 alpha-2u globulin PGCL4 0.030
Notch4 Notch homolog 4 (Drosophila) 0.030
A1cf APOBEC1 complementation factor 0.029
Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 0.029
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.029
Dock8 dedicator of cytokinesis 8 0.029
Egr2 early growth response 2 0.029
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.028
Il10ra interleukin 10 receptor, alpha 0.028
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult 0.028
F13a1 coagulation factor XIII, A1 polypeptide 0.028
Tkt transketolase 0.028
Tat tyrosine aminotransferase 0.027
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.027
Rara retinoic acid receptor, alpha 0.027
Meox2 mesenchyme homeobox 2 0.026
Hibadh 3-hydroxyisobutyrate dehydrogenase 0.026
Bcan brevican 0.026
Junb jun B proto-oncogene 0.026
Sec1 secretory blood group 1 0.026
Fgfr4 fibroblast growth factor receptor 4 0.026
Gstm2 glutathione S-transferase mu 2 0.026
Gjb4 gap junction protein, beta 4 0.025
Maoa monoamine oxidase A 0.025
RT1-Ba RT1 class II, locus Ba 0.025
Apoa4 apolipoprotein A-IV 0.025
Pdk2 pyruvate dehydrogenase kinase, isozyme 2 0.025
Oprm1 opioid receptor, mu 1 0.024
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.024
Prl8a7 prolactin family 8, subfamily a, member 7 0.024
Rxra retinoid X receptor alpha 0.024
Hist1h1a histone cluster 1, H1a 0.024
Chordc1 cysteine and histidine-rich domain (CHORD)-containing 1 0.024
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.024
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.024
Synpo synaptopodin 0.024
Pxmp2 peroxisomal membrane protein 2 0.024
Aplnr apelin receptor 0.024
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.024
Creb1 cAMP responsive element binding protein 1 0.023
Usf2 upstream transcription factor 2, c-fos interacting 0.023
Utrn utrophin 0.023
Obp1f odorant binding protein I f 0.023
Hfe hemochromatosis 0.023
Aprt adenine phosphoribosyl transferase 0.023
Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C 0.023
Manea mannosidase, endo-alpha 0.023
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.023
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.023
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.022
Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 0.022
Tspan18 tetraspanin 18 0.022
Myo9a myosin IXA 0.022
Catsper2 cation channel, sperm associated 2 0.022
Zadh2 zinc binding alcohol dehydrogenase, domain containing 2 0.022
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.022
Acsl1 acyl-CoA synthetase long-chain family member 1 0.021
Olr59 olfactory receptor 59 0.021
Pdk4 pyruvate dehydrogenase kinase, isozyme 4 0.021
Dusp1 dual specificity phosphatase 1 0.021
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.021
Mmp23 matrix metallopeptidase 23 0.021
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GSY2 Gsy2p 0.998
PIG2 Pig2p 0.981
PHO85 Pho85p 0.946
GSY1 Gsy1p 0.945
CHS3 Chs3p 0.941
UGP1 Ugp1p 0.937
ENO1 Eno1p 0.926
GLG2 Glg2p 0.889
HOR2 Hor2p 0.878
HXK1 Hxk1p 0.873
PGK1 Pgk1p 0.863
FYV10 Fyv10p 0.855
GIP2 Gip2p 0.849
GPH1 Gph1p 0.832
ENO2 Eno2p 0.814
TDH3 Tdh3p 0.812
FBA1 Fba1p 0.811
VID24 Vid24p 0.785
CHS6 Chs6p 0.771
BCH2 Bch2p 0.756
RMD5 Rmd5p 0.746
TDH1 Tdh1p 0.712
SOR1 Sor1p 0.672
SOR2 Sor2p 0.652
MLS1 Mls1p 0.618
TDH2 Tdh2p 0.582
BUD7 Bud7p 0.573
TPI1 Tpi1p 0.569
TPK1 Tpk1p 0.559
ARP8 Arp8p 0.548
ERR1 Err1p 0.542
PGM2 Pgm2p 0.513
GPM1 Gpm1p 0.485
GID7 Gid7p 0.464
CHS5 Chs5p 0.434
GID8 Gid8p 0.429
ERR2 Err2p 0.411
TPS2 Tps2p 0.382
GAC1 Gac1p 0.377
HOC1 Hoc1p 0.365
ADH1 Adh1p 0.359
ROT2 Rot2p 0.352
MOH1 Moh1p 0.346
GDB1 Gdb1p 0.341
RHO1 Rho1p 0.339
RDI1 Rdi1p 0.327
SLG1 Slg1p 0.273
PYC2 Pyc2p 0.262
CAT8 Cat8p 0.258
BDH1 Bdh1p 0.258
SAK1 Sak1p 0.257
SSA4 Ssa4p 0.256
ERR3 Err3p 0.247
BDH2 Bdh2p 0.244
CKB2 Ckb2p 0.240
VID30 Vid30p 0.235
AGP2 Agp2p 0.234
TPS1 Tps1p 0.225
LYS5 Lys5p 0.225
YKL187C hypothetical protein 0.225
PHO80 Pho80p 0.221
PYC1 Pyc1p 0.221
CDC19 Cdc19p 0.211
HUG1 Hug1p 0.210
MMR1 Mmr1p 0.207
SAC7 Sac7p 0.207
PCL2 Pcl2p 0.207
ICL1 Icl1p 0.204
HXT3 Hxt3p 0.201
CTI6 Cti6p 0.196
YAP6 Yap6p 0.195
SPO1 Spo1p 0.193
PSK2 Psk2p 0.180
GAT2 Gat2p 0.177
SLT2 Slt2p 0.177
TPS3 Tps3p 0.166
GND2 Gnd2p 0.165
HKR1 Hkr1p 0.164
YIG1 Yig1p 0.161
CAK1 Cak1p 0.160
VID28 Vid28p 0.160
YLR149C hypothetical protein 0.155
YMR291W hypothetical protein 0.146
BEM1 Bem1p 0.144
RHR2 Rhr2p 0.143
GLC7 Glc7p 0.142
GLN3 Gln3p 0.142
YPL014W hypothetical protein 0.141
YGR205W hypothetical protein 0.139
GLG1 Glg1p 0.138
YLR001C hypothetical protein 0.137
DSK2 Dsk2p 0.135
GPD1 Gpd1p 0.134
WWM1 Wwm1p 0.133
XKS1 Xks1p 0.131
ANP1 Anp1p 0.130
PIL1 Pil1p 0.125
EMI2 Emi2p 0.124
CYK3 Cyk3p 0.122
YNL194C hypothetical protein 0.120