The network for 'cerebral cortex development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cerebral cortex development

The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.

Mus musculus
Name Description Probability Func Analog Organism
Pax6 paired box gene 6 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Shh sonic hedgehog 1.000
Pax3 paired box gene 3 1.000
Lhx3 LIM homeobox protein 3 1.000
Foxg1 forkhead box G1 0.999
Dab1 disabled homolog 1 (Drosophila) 0.998
Tbx3 T-box 3 0.998
Pax2 paired box gene 2 0.998
Emx1 empty spiracles homolog 1 (Drosophila) 0.998
Pitx2 paired-like homeodomain transcription factor 2 0.998
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.998
Foxc1 forkhead box C1 0.997
Isl1 ISL1 transcription factor, LIM/homeodomain 0.997
Sox2 SRY-box containing gene 2 0.997
Gli3 GLI-Kruppel family member GLI3 0.993
Hand1 heart and neural crest derivatives expressed transcript 1 0.991
Fgfr2 fibroblast growth factor receptor 2 0.980
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.979
Insm1 insulinoma-associated 1 0.973
Bbs4 Bardet-Biedl syndrome 4 (human) 0.970
Alx3 aristaless-like homeobox 3 0.958
Pou3f3 POU domain, class 3, transcription factor 3 0.952
Lepr leptin receptor 0.949
Rarg retinoic acid receptor, gamma 0.942
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.942
Lhx1 LIM homeobox protein 1 0.940
Hand2 heart and neural crest derivatives expressed transcript 2 0.940
Bmp4 bone morphogenetic protein 4 0.937
Nog noggin 0.929
Ctnnb1 catenin (cadherin associated protein), beta 1 0.927
Gli2 GLI-Kruppel family member GLI2 0.923
Lmx1a LIM homeobox transcription factor 1 alpha 0.922
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.921
Egfr epidermal growth factor receptor 0.921
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.918
Sox3 SRY-box containing gene 3 0.913
Fgf8 fibroblast growth factor 8 0.907
Emx2 empty spiracles homolog 2 (Drosophila) 0.903
Fgf10 fibroblast growth factor 10 0.902
Pthlh parathyroid hormone-like peptide 0.895
Lef1 lymphoid enhancer binding factor 1 0.895
Chd7 chromodomain helicase DNA binding protein 7 0.891
Pitx1 paired-like homeodomain transcription factor 1 0.890
Msx1 homeobox, msh-like 1 0.882
Tbx15 T-box 15 0.881
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.875
Ptf1a pancreas specific transcription factor, 1a 0.873
Sox11 SRY-box containing gene 11 0.866
Gsc goosecoid homeobox 0.865
Ntf3 neurotrophin 3 0.856
T brachyury 0.855
Pax8 paired box gene 8 0.853
Uncx UNC homeobox 0.848
Hoxa1 homeobox A1 0.847
Tcfap2a transcription factor AP-2, alpha 0.826
Eya1 eyes absent 1 homolog (Drosophila) 0.825
Phox2b paired-like homeobox 2b 0.825
Hes5 hairy and enhancer of split 5 (Drosophila) 0.813
Neurod1 neurogenic differentiation 1 0.806
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.805
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.795
Phox2a paired-like homeobox 2a 0.793
Tlx3 T-cell leukemia, homeobox 3 0.792
Alx4 aristaless-like homeobox 4 0.788
Sox10 SRY-box containing gene 10 0.786
Tgfb2 transforming growth factor, beta 2 0.785
Hes1 hairy and enhancer of split 1 (Drosophila) 0.782
Bdnf brain derived neurotrophic factor 0.779
Pax1 paired box gene 1 0.778
Efnb2 ephrin B2 0.776
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.770
Notch1 Notch gene homolog 1 (Drosophila) 0.768
Snai1 snail homolog 1 (Drosophila) 0.767
Fgfr1 fibroblast growth factor receptor 1 0.762
Rxra retinoid X receptor alpha 0.762
Psen1 presenilin 1 0.762
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.761
Hoxd13 homeobox D13 0.759
Chrd chordin 0.758
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.733
Pou4f2 POU domain, class 4, transcription factor 2 0.725
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.711
Prrx1 paired related homeobox 1 0.708
Neurog2 neurogenin 2 0.706
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.695
Bcl2 B-cell leukemia/lymphoma 2 0.688
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.677
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.670
Msx3 homeobox, msh-like 3 0.669
Neurog3 neurogenin 3 0.668
Msx2 homeobox, msh-like 2 0.663
Foxc2 forkhead box C2 0.660
Fgf3 fibroblast growth factor 3 0.655
Bmp5 bone morphogenetic protein 5 0.645
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.644
Lrp6 low density lipoprotein receptor-related protein 6 0.643
Otx1 orthodenticle homolog 1 (Drosophila) 0.635
Nhlh1 nescient helix loop helix 1 0.622
Dlx5 distal-less homeobox 5 0.620
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PEX14 peroxisomal biogenesis factor 14 0.937
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.918
DLG4 discs, large homolog 4 (Drosophila) 0.848
PEX19 peroxisomal biogenesis factor 19 0.577
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.555
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.527
LAMB1 laminin, beta 1 0.500
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.440
PAX3 paired box 3 0.348
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.341
TSC2 tuberous sclerosis 2 0.309
NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 0.301
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.287
AXIN1 axin 1 0.265
LRRK2 leucine-rich repeat kinase 2 0.219
GSK3B glycogen synthase kinase 3 beta 0.193
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.171
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.162
CPE carboxypeptidase E 0.144
BCL2L1 BCL2-like 1 0.142
BBS2 Bardet-Biedl syndrome 2 0.138
BAK1 BCL2-antagonist/killer 1 0.137
MAPT microtubule-associated protein tau 0.137
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.128
DEAF1 deformed epidermal autoregulatory factor 1 (Drosophila) 0.123
ASB2 ankyrin repeat and SOCS box containing 2 0.118
VEGFA vascular endothelial growth factor A 0.111
POU5F1 POU class 5 homeobox 1 0.111
APP amyloid beta (A4) precursor protein 0.108
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 0.107
SNAPIN SNAP-associated protein 0.102
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.099
PEX12 peroxisomal biogenesis factor 12 0.098
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.098
RPL18A ribosomal protein L18a 0.096
SORBS3 sorbin and SH3 domain containing 3 0.087
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.084
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.073
APC adenomatous polyposis coli 0.072
SPTBN4 spectrin, beta, non-erythrocytic 4 0.071
PDIA3 protein disulfide isomerase family A, member 3 0.062
MAP1A microtubule-associated protein 1A 0.059
BICD1 bicaudal D homolog 1 (Drosophila) 0.057
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.051
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.049
TMEM173 transmembrane protein 173 0.048
LAMA4 laminin, alpha 4 0.046
RTKN rhotekin 0.045
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.044
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.044
ASB7 ankyrin repeat and SOCS box containing 7 0.042
RNF144B ring finger protein 144B 0.041
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.040
PAX8 paired box 8 0.040
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.039
PCDHA4 protocadherin alpha 4 0.038
BBS1 Bardet-Biedl syndrome 1 0.037
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.034
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.032
CLIP1 CAP-GLY domain containing linker protein 1 0.030
PKP4 plakophilin 4 0.029
C14orf129 chromosome 14 open reading frame 129 0.029
CKAP5 cytoskeleton associated protein 5 0.028
BBS9 Bardet-Biedl syndrome 9 0.025
NIN ninein (GSK3B interacting protein) 0.025
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.024
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.024
CUL2 cullin 2 0.024
TNRC6A trinucleotide repeat containing 6A 0.023
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.021
GATAD2B GATA zinc finger domain containing 2B 0.021
FOXD3 forkhead box D3 0.020
PCM1 pericentriolar material 1 0.020
E2F1 E2F transcription factor 1 0.019
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.019
DEFA1 defensin, alpha 1 0.019
COL5A2 collagen, type V, alpha 2 0.019
RNR2 l-rRNA 0.019
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.018
NCK2 NCK adaptor protein 2 0.018
FBN1 fibrillin 1 0.018
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.018
IGF1R insulin-like growth factor 1 receptor 0.018
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.018
SIX3 SIX homeobox 3 0.017
NLGN1 neuroligin 1 0.017
ATN1 atrophin 1 0.017
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.017
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.017
CDK5 cyclin-dependent kinase 5 0.016
TTC8 tetratricopeptide repeat domain 8 0.016
ASB1 ankyrin repeat and SOCS box containing 1 0.016
EXOC7 exocyst complex component 7 0.016
NTF4 neurotrophin 4 0.016
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.016
SOX10 SRY (sex determining region Y)-box 10 0.015
KIF1C kinesin family member 1C 0.015
ATXN3 ataxin 3 0.015
SALL2 sal-like 2 (Drosophila) 0.015
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.014
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Rattus norvegicus
Name Description Probability Func Analog Organism
Col1a2 collagen, type I, alpha 2 0.071
Col5a2 collagen, type V, alpha 2 0.071
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.062
Drd1a dopamine receptor D1A 0.051
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.047
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.038
Dlg4 discs, large homolog 4 (Drosophila) 0.037
Syn1 synapsin I 0.036
Ahr aryl hydrocarbon receptor 0.034
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.032
Fgfr2 fibroblast growth factor receptor 2 0.031
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.031
Pex5l peroxisomal biogenesis factor 5-like 0.030
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.028
C8b complement component 8, beta polypeptide 0.026
Sparc secreted protein, acidic, cysteine-rich (osteonectin) 0.026
Ecel1 endothelin converting enzyme-like 1 0.025
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.024
Unc5b unc-5 homolog B (C. elegans) 0.024
Pigl phosphatidylinositol glycan anchor biosynthesis, class L 0.024
Pax8 paired box 8 0.023
Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 0.023
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.023
Col1a1 collagen, type I, alpha 1 0.023
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.022
Nfib nuclear factor I/B 0.022
Znf532 zinc finger protein 532 0.021
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.018
Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 0.018
Pou2f2 POU class 2 homeobox 2 0.018
Camk2d calcium/calmodulin-dependent protein kinase II delta 0.018
Sirpa signal-regulatory protein alpha 0.017
Pnoc prepronociceptin 0.017
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.016
Cnksr2 connector enhancer of kinase suppressor of Ras 2 0.016
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.016
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.016
Myo1c myosin IC 0.016
Gdf11 growth differentiation factor 11 0.016
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.016
Oprm1 opioid receptor, mu 1 0.015
Ptprf protein tyrosine phosphatase, receptor type, F 0.015
Srebf1 sterol regulatory element binding transcription factor 1 0.015
Nrxn3 neurexin 3 0.015
Lamc1 laminin, gamma 1 0.015
Cbs cystathionine beta synthase 0.015
Prkcb protein kinase C, beta 0.014
Rhoa ras homolog gene family, member A 0.014
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.014
Lin7b lin-7 homolog b (C. elegans) 0.014
Cckbr cholecystokinin B receptor 0.014
Gsg1l GSG1-like 0.014
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.014
Hoxc4 homeo box C4 0.014
Cd86 CD86 molecule 0.013
Nolc1 nucleolar and coiled-body phosphoprotein 1 0.013
Ednrb endothelin receptor type B 0.013
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.013
Rorb RAR-related orphan receptor B 0.013
Ubqln1 ubiquilin 1 0.013
Epha7 Eph receptor A7 0.013
Adra2c adrenergic, alpha-2C-, receptor 0.013
Mprip myosin phosphatase Rho interacting protein 0.012
Tbx2 T-box 2 0.012
Strn striatin, calmodulin binding protein 0.012
Ptprd protein tyrosine phosphatase, receptor type, D 0.012
LOC100364485 mCG1051031-like 0.012
Hist1h2bh histone cluster 1, H2bh 0.012
Aqp4 aquaporin 4 0.012
Rabep1 rabaptin, RAB GTPase binding effector protein 1 0.012
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.011
Ubc ubiquitin C 0.011
Ptprz1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.011
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.011
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.011
Gc group specific component 0.011
St18 suppression of tumorigenicity 18 0.011
Gucy1a2 guanylate cyclase 1, soluble, alpha 2 0.011
Cpb1 carboxypeptidase B1 (tissue) 0.011
Fgf21 fibroblast growth factor 21 0.011
Kcnf1 potassium voltage-gated channel, subfamily F, member 1 0.011
Fgf5 fibroblast growth factor 5 0.011
Fam65a family with sequence similarity 65, member A 0.011
Gfra2 GDNF family receptor alpha 2 0.011
Baiap2 BAI1-associated protein 2 0.011
Scarb1 scavenger receptor class B, member 1 0.010
A1bg alpha-1-B glycoprotein 0.010
Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.010
Hpx hemopexin 0.010
Mapk1 mitogen activated protein kinase 1 0.010
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.010
Atrn attractin 0.010
Hspa4 heat shock protein 4 0.010
Cntfr ciliary neurotrophic factor receptor 0.010
Sardh sarcosine dehydrogenase 0.010
Pdpk1 3-phosphoinositide dependent protein kinase-1 0.010
Plxna2 plexin A2 0.010
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism