The network for 'cd4 positive alpha beta t cell cytokine production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cd4 positive alpha beta t cell cytokine production

Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.

Mus musculus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.999
Ccl12 chemokine (C-C motif) ligand 12 0.994
Ccl7 chemokine (C-C motif) ligand 7 0.992
Ccl4 chemokine (C-C motif) ligand 4 0.979
Tnf tumor necrosis factor 0.975
Ccl8 chemokine (C-C motif) ligand 8 0.960
Ifng interferon gamma 0.922
Il1b interleukin 1 beta 0.919
Cd40 CD40 antigen 0.887
Ccl3 chemokine (C-C motif) ligand 3 0.867
Ccr1 chemokine (C-C motif) receptor 1 0.856
Fcgr1 Fc receptor, IgG, high affinity I 0.837
Ccl9 chemokine (C-C motif) ligand 9 0.760
Cxcl2 chemokine (C-X-C motif) ligand 2 0.748
Ccr2 chemokine (C-C motif) receptor 2 0.743
Ch25h cholesterol 25-hydroxylase 0.728
Clec4d C-type lectin domain family 4, member d 0.707
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.702
C3ar1 complement component 3a receptor 1 0.697
Icos inducible T-cell co-stimulator 0.681
Il6 interleukin 6 0.666
Mmp12 matrix metallopeptidase 12 0.650
Cxcl1 chemokine (C-X-C motif) ligand 1 0.540
Itgax integrin alpha X 0.529
Irf7 interferon regulatory factor 7 0.524
Cd14 CD14 antigen 0.523
Akt1 thymoma viral proto-oncogene 1 0.508
Mx2 myxovirus (influenza virus) resistance 2 0.505
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.501
Msr1 macrophage scavenger receptor 1 0.487
Cxcl9 chemokine (C-X-C motif) ligand 9 0.469
Ubd ubiquitin D 0.444
Cxcl10 chemokine (C-X-C motif) ligand 10 0.439
Irg1 immunoresponsive gene 1 0.421
Ccl22 chemokine (C-C motif) ligand 22 0.367
Saa3 serum amyloid A 3 0.356
Gzma granzyme A 0.352
Cd151 CD151 antigen 0.351
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.321
Csf3 colony stimulating factor 3 (granulocyte) 0.320
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.307
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.293
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.285
Lag3 lymphocyte-activation gene 3 0.256
Folr2 folate receptor 2 (fetal) 0.254
Cd40lg CD40 ligand 0.247
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.247
Selp selectin, platelet 0.236
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.218
Lep leptin 0.214
Has1 hyaluronan synthase1 0.213
Gdf15 growth differentiation factor 15 0.211
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.211
Sh2d2a SH2 domain protein 2A 0.207
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.203
Klrb1c killer cell lectin-like receptor subfamily B member 1C 0.194
Il1rn interleukin 1 receptor antagonist 0.188
Cst7 cystatin F (leukocystatin) 0.179
Vhl von Hippel-Lindau tumor suppressor 0.168
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.166
Ctsw cathepsin W 0.166
Timp1 tissue inhibitor of metalloproteinase 1 0.162
Sele selectin, endothelial cell 0.162
Smr3a submaxillary gland androgen regulated protein 3A 0.160
Gm11428 predicted gene 11428 0.156
Ccl6 chemokine (C-C motif) ligand 6 0.156
Fcgr2b Fc receptor, IgG, low affinity IIb 0.150
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.149
Cd28 CD28 antigen 0.148
Ccr7 chemokine (C-C motif) receptor 7 0.147
Ccr5 chemokine (C-C motif) receptor 5 0.142
Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) 0.141
Ifnab interferon alpha B 0.130
Il2rb interleukin 2 receptor, beta chain 0.128
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.128
Atf3 activating transcription factor 3 0.126
Cd3d CD3 antigen, delta polypeptide 0.125
Gzmb granzyme B 0.123
Fpr3 formyl peptide receptor 3 0.121
Tyrobp TYRO protein tyrosine kinase binding protein 0.117
Lta lymphotoxin A 0.106
Batf2 basic leucine zipper transcription factor, ATF-like 2 0.106
Ccl17 chemokine (C-C motif) ligand 17 0.105
Fas Fas (TNF receptor superfamily member 6) 0.104
C1qb complement component 1, q subcomponent, beta polypeptide 0.100
Cd7 CD7 antigen 0.098
Lyz2 lysozyme 2 0.094
AI607873 expressed sequence AI607873 0.094
AF251705 cDNA sequence AF251705 0.092
Ifna2 interferon alpha 2 0.092
Lgals3 lectin, galactose binding, soluble 3 0.092
Mapkap1 mitogen-activated protein kinase associated protein 1 0.088
Ifna5 interferon alpha 5 0.086
Bcl3 B-cell leukemia/lymphoma 3 0.084
Xcl1 chemokine (C motif) ligand 1 0.082
Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C 0.082
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.081
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.081
Cd86 CD86 antigen 0.080
Lcn2 lipocalin 2 0.078
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
NUMB numb homolog (Drosophila) 1.000
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.894
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.887
IL4R interleukin 4 receptor 0.866
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.843
ZNF71 zinc finger protein 71 0.741
CCDC115 coiled-coil domain containing 115 0.676
CPD carboxypeptidase D 0.450
CD164 CD164 molecule, sialomucin 0.404
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.319
VHL von Hippel-Lindau tumor suppressor 0.317
IFNA17 interferon, alpha 17 0.313
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.306
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.264
F11R F11 receptor 0.190
IFNA4 interferon, alpha 4 0.170
TM9SF2 transmembrane 9 superfamily member 2 0.114
NMT2 N-myristoyltransferase 2 0.112
LBP lipopolysaccharide binding protein 0.107
ADAM10 ADAM metallopeptidase domain 10 0.099
SNAP23 synaptosomal-associated protein, 23kDa 0.093
IL3 interleukin 3 (colony-stimulating factor, multiple) 0.090
WWC1 WW and C2 domain containing 1 0.085
IFNA10 interferon, alpha 10 0.083
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.082
VAMP3 vesicle-associated membrane protein 3 (cellubrevin) 0.072
IFNA14 interferon, alpha 14 0.069
IL13RA1 interleukin 13 receptor, alpha 1 0.062
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 0.057
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.055
GYPB glycophorin B (MNS blood group) 0.055
IL5 interleukin 5 (colony-stimulating factor, eosinophil) 0.051
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.051
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.051
IFNA16 interferon, alpha 16 0.049
SERINC1 serine incorporator 1 0.047
PICALM phosphatidylinositol binding clathrin assembly protein 0.047
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.046
IFNA21 interferon, alpha 21 0.045
IFNB1 interferon, beta 1, fibroblast 0.045
IFNA2 interferon, alpha 2 0.041
OASL 2'-5'-oligoadenylate synthetase-like 0.041
IFNA13 interferon, alpha 13 0.041
IL2 interleukin 2 0.039
CXCL11 chemokine (C-X-C motif) ligand 11 0.038
IL9 interleukin 9 0.037
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.034
EPSTI1 epithelial stromal interaction 1 (breast) 0.033
C6orf10 chromosome 6 open reading frame 10 0.033
PRKCI protein kinase C, iota 0.032
IAPP islet amyloid polypeptide 0.032
SPO11 SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae) 0.031
LECT2 leukocyte cell-derived chemotaxin 2 0.031
RAB1A RAB1A, member RAS oncogene family 0.031
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.031
COLEC10 collectin sub-family member 10 (C-type lectin) 0.030
NMBR neuromedin B receptor 0.030
KEAP1 kelch-like ECH-associated protein 1 0.029
SEMG2 semenogelin II 0.028
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.028
RRH retinal pigment epithelium-derived rhodopsin homolog 0.027
SOCS1 suppressor of cytokine signaling 1 0.027
IL21 interleukin 21 0.026
AFM afamin 0.026
TAS2R8 taste receptor, type 2, member 8 0.026
FGL1 fibrinogen-like 1 0.025
ANGPTL3 angiopoietin-like 3 0.025
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.024
IFNA5 interferon, alpha 5 0.024
TRIM48 tripartite motif containing 48 0.023
IFNA8 interferon, alpha 8 0.023
C4BPB complement component 4 binding protein, beta 0.023
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 0.023
IFI44L interferon-induced protein 44-like 0.023
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.023
ANXA4 annexin A4 0.022
TAS2R7 taste receptor, type 2, member 7 0.022
TAS2R16 taste receptor, type 2, member 16 0.022
RIOK3 RIO kinase 3 (yeast) 0.022
PDPK1 3-phosphoinositide dependent protein kinase-1 0.021
OR5P2 olfactory receptor, family 5, subfamily P, member 2 0.021
OR2B2 olfactory receptor, family 2, subfamily B, member 2 0.021
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.021
FSHR follicle stimulating hormone receptor 0.021
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 0.020
GLYAT glycine-N-acyltransferase 0.020
SERINC3 serine incorporator 3 0.020
CLDN17 claudin 17 0.020
OR7A10 olfactory receptor, family 7, subfamily A, member 10 0.020
IMPG1 interphotoreceptor matrix proteoglycan 1 0.020
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.019
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.019
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 0.019
SCARB2 scavenger receptor class B, member 2 0.019
LRRK2 leucine-rich repeat kinase 2 0.019
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.018
TSHB thyroid stimulating hormone, beta 0.018
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.018
SETD7 SET domain containing (lysine methyltransferase) 7 0.018
PMP2 peripheral myelin protein 2 0.018
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism