IMP
Process View
The network for 'positive regulation of transcription from rna polymerase ii promoter involved in heart development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of transcription from rna polymerase ii promoter involved in heart development
Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.999 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.999 | |
| Pax3 | paired box gene 3 | 0.996 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.995 | |
| Pax2 | paired box gene 2 | 0.993 | |
| Tbx3 | T-box 3 | 0.991 | |
| Fgf8 | fibroblast growth factor 8 | 0.990 | |
| Hoxa1 | homeobox A1 | 0.990 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.990 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.987 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.986 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.985 | |
| Foxc1 | forkhead box C1 | 0.984 | |
| Bmp4 | bone morphogenetic protein 4 | 0.982 | |
| Foxc2 | forkhead box C2 | 0.982 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.982 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.981 | |
| Dlx5 | distal-less homeobox 5 | 0.979 | |
| Msx1 | homeobox, msh-like 1 | 0.979 | |
| Foxg1 | forkhead box G1 | 0.977 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.973 | |
| Chrd | chordin | 0.959 | |
| Prrx1 | paired related homeobox 1 | 0.958 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.954 | |
| Sox9 | SRY-box containing gene 9 | 0.928 | |
| Tbx5 | T-box 5 | 0.920 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.885 | |
| Sall4 | sal-like 4 (Drosophila) | 0.875 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.866 | |
| Fgf10 | fibroblast growth factor 10 | 0.856 | |
| Msx2 | homeobox, msh-like 2 | 0.826 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.814 | |
| Rarg | retinoic acid receptor, gamma | 0.798 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.762 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.750 | |
| Hoxa3 | homeobox A3 | 0.746 | |
| Rarb | retinoic acid receptor, beta | 0.734 | |
| Tbx1 | T-box 1 | 0.732 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.673 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.654 | |
| Gsc | goosecoid homeobox | 0.651 | |
| Gja5 | gap junction protein, alpha 5 | 0.645 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.620 | |
| Runx2 | runt related transcription factor 2 | 0.613 | |
| Nodal | nodal | 0.598 | |
| Wt1 | Wilms tumor 1 homolog | 0.596 | |
| Prrx2 | paired related homeobox 2 | 0.581 | |
| Jag1 | jagged 1 | 0.573 | |
| Gata4 | GATA binding protein 4 | 0.560 | |
| Bmp7 | bone morphogenetic protein 7 | 0.548 | |
| Pax9 | paired box gene 9 | 0.498 | |
| Hoxa2 | homeobox A2 | 0.498 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.496 | |
| Lhx1 | LIM homeobox protein 1 | 0.482 | |
| Efnb2 | ephrin B2 | 0.467 | |
| Hoxd11 | homeobox D11 | 0.461 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.453 | |
| Tbx4 | T-box 4 | 0.447 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.430 | |
| Sox2 | SRY-box containing gene 2 | 0.397 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.390 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.378 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.375 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.373 | |
| Smo | smoothened homolog (Drosophila) | 0.372 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.365 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.352 | |
| Vegfa | vascular endothelial growth factor A | 0.351 | |
| Rxra | retinoid X receptor alpha | 0.329 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.322 | |
| Tcf21 | transcription factor 21 | 0.320 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.312 | |
| Hoxa11 | homeobox A11 | 0.308 | |
| Hoxd3 | homeobox D3 | 0.304 | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.303 | |
| Ednra | endothelin receptor type A | 0.302 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.298 | |
| Alx1 | ALX homeobox 1 | 0.285 | |
| Nog | noggin | 0.284 | |
| Hoxa13 | homeobox A13 | 0.282 | |
| T | brachyury | 0.279 | |
| Sall1 | sal-like 1 (Drosophila) | 0.273 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.237 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.225 | |
| Nanog | Nanog homeobox | 0.225 | |
| Hmx3 | H6 homeobox 3 | 0.224 | |
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.219 | |
| Gata6 | GATA binding protein 6 | 0.207 | |
| Rara | retinoic acid receptor, alpha | 0.199 | |
| Gata3 | GATA binding protein 3 | 0.194 | |
| Sox11 | SRY-box containing gene 11 | 0.188 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.180 | |
| Dlx2 | distal-less homeobox 2 | 0.177 | |
| Mesp1 | mesoderm posterior 1 | 0.168 | |
| Fgf3 | fibroblast growth factor 3 | 0.162 | |
| Hoxd13 | homeobox D13 | 0.150 | |
| Trp63 | transformation related protein 63 | 0.149 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.146 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 1.000 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.999 | |
| MKL1 | megakaryoblastic leukemia (translocation) 1 | 0.984 | |
| BTF3 | basic transcription factor 3 | 0.971 | |
| MYOG | myogenin (myogenic factor 4) | 0.930 | |
| MYOD1 | myogenic differentiation 1 | 0.904 | |
| MYOCD | myocardin | 0.861 | |
| SMAD1 | SMAD family member 1 | 0.853 | |
| GATA4 | GATA binding protein 4 | 0.748 | |
| FUNDC2 | FUN14 domain containing 2 | 0.558 | |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.455 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.455 | |
| MKL2 | MKL/myocardin-like 2 | 0.367 | |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.270 | |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.152 | |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.144 | |
| RPL36AL | ribosomal protein L36a-like | 0.128 | |
| RPL34 | ribosomal protein L34 | 0.079 | |
| SMAD7 | SMAD family member 7 | 0.070 | |
| TBX1 | T-box 1 | 0.054 | |
| RPL36A | ribosomal protein L36a | 0.048 | |
| SOX18 | SRY (sex determining region Y)-box 18 | 0.045 | |
| TBX5 | T-box 5 | 0.044 | |
| SMAD6 | SMAD family member 6 | 0.043 | |
| PML | promyelocytic leukemia | 0.042 | |
| AR | androgen receptor | 0.040 | |
| GATA5 | GATA binding protein 5 | 0.039 | |
| FOXF1 | forkhead box F1 | 0.039 | |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.037 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.034 | |
| MSX1 | msh homeobox 1 | 0.033 | |
| PYY | peptide YY | 0.033 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.031 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.029 | |
| SMAD4 | SMAD family member 4 | 0.027 | |
| ZHX1 | zinc fingers and homeoboxes 1 | 0.027 | |
| NSF | N-ethylmaleimide-sensitive factor | 0.027 | |
| ARL15 | ADP-ribosylation factor-like 15 | 0.027 | |
| LBX1 | ladybird homeobox 1 | 0.026 | |
| IL2RB | interleukin 2 receptor, beta | 0.026 | |
| RPL26 | ribosomal protein L26 | 0.023 | |
| RPL17 | ribosomal protein L17 | 0.022 | |
| HOXD12 | homeobox D12 | 0.021 | |
| COL13A1 | collagen, type XIII, alpha 1 | 0.021 | |
| HOXD9 | homeobox D9 | 0.021 | |
| COL2A1 | collagen, type II, alpha 1 | 0.020 | |
| FGF3 | fibroblast growth factor 3 | 0.019 | |
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.019 | |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 | 0.019 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.018 | |
| BANP | BTG3 associated nuclear protein | 0.017 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.017 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.017 | |
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.017 | |
| FGF18 | fibroblast growth factor 18 | 0.017 | |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.017 | |
| HOXB13 | homeobox B13 | 0.017 | |
| AKR1C3 | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 0.017 | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.016 | |
| HOXC11 | homeobox C11 | 0.016 | |
| GNLY | granulysin | 0.016 | |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.016 | |
| RPL35A | ribosomal protein L35a | 0.016 | |
| KIR3DL2 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 | 0.016 | |
| VAX2 | ventral anterior homeobox 2 | 0.016 | |
| FOXF2 | forkhead box F2 | 0.016 | |
| EGR1 | early growth response 1 | 0.016 | |
| NFYA | nuclear transcription factor Y, alpha | 0.015 | |
| SIX2 | SIX homeobox 2 | 0.015 | |
| LTK | leukocyte receptor tyrosine kinase | 0.015 | |
| YAP1 | Yes-associated protein 1 | 0.015 | |
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.015 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.015 | |
| ZNF33B | zinc finger protein 33B | 0.015 | |
| ELK1 | ELK1, member of ETS oncogene family | 0.015 | |
| DLL4 | delta-like 4 (Drosophila) | 0.015 | |
| NKX2-8 | NK2 homeobox 8 | 0.014 | |
| MYH6 | myosin, heavy chain 6, cardiac muscle, alpha | 0.014 | |
| COMP | cartilage oligomeric matrix protein | 0.014 | |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.014 | |
| GATA2 | GATA binding protein 2 | 0.014 | |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.014 | |
| CD7 | CD7 molecule | 0.014 | |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.014 | |
| HOXA11 | homeobox A11 | 0.014 | |
| GTF2I | general transcription factor IIi | 0.014 | |
| PFDN5 | prefoldin subunit 5 | 0.014 | |
| RPL41 | ribosomal protein L41 | 0.014 | |
| PGR | progesterone receptor | 0.013 | |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.013 | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.013 | |
| HOXC8 | homeobox C8 | 0.013 | |
| DLX4 | distal-less homeobox 4 | 0.013 | |
| IRX5 | iroquois homeobox 5 | 0.013 | |
| FOXL1 | forkhead box L1 | 0.013 | |
| GATA3 | GATA binding protein 3 | 0.013 | |
| HOXD11 | homeobox D11 | 0.013 | |
| TBX2 | T-box 2 | 0.013 | |
| KLHL35 | kelch-like 35 (Drosophila) | 0.013 | |
| CHRDL2 | chordin-like 2 | 0.013 |