The network for 'cellular macromolecule metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

Name Description Probability Func Analog Organism
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.995
chd chordin 0.995
dlx2a distal-less homeobox gene 2a 0.994
notch1a notch homolog 1a 0.989
shha sonic hedgehog a 0.987
runx2b runt-related transcription factor 2b 0.985
tfap2a transcription factor AP-2 alpha 0.983
tp53 tumor protein p53 0.983
smo smoothened homolog (Drosophila) 0.981
dlx5a distal-less homeobox gene 5a 0.981
lhx1a LIM homeobox 1a 0.981
sox9a SRY-box containing gene 9a 0.980
bmp4 bone morphogenetic protein 4 0.980
evx1 even-skipped homeobox 1 0.976
tll1 tolloid-like 1 0.969
ndr2 nodal-related 2 0.965
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.965
foxi1 forkhead box I1 0.963
bmp2b bone morphogenetic protein 2b 0.963
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.961
spry4 sprouty (Drosophila) homolog 4 0.959
gli1 GLI-Kruppel family member 1 0.959
foxa2 forkhead box A2 0.957
fgfr1a fibroblast growth factor receptor 1a 0.956
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.956
tal1 T-cell acute lymphocytic leukemia 1 0.953
her6 hairy-related 6 0.952
myod1 myogenic differentiation 1 0.952
fgf3 fibroblast growth factor 3 0.951
runx2a runt-related transcription factor 2a 0.951
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.950
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.948
pcdh18b protocadherin 18b 0.946
otpa orthopedia homolog a 0.937
cav1 caveolin 1 0.934
hoxb1b homeo box B1b 0.930
pcna proliferating cell nuclear antigen 0.930
pou5f1 POU domain, class 5, transcription factor 1 0.928
fli1a friend leukemia integration 1a 0.924
pax2a paired box gene 2a 0.916
nkx2.2a NK2 transcription factor related 2a 0.913
socs1 suppressor of cytokine signaling 1 0.912
alas2 aminolevulinate, delta-, synthetase 2 0.911
sf3b1 splicing factor 3b, subunit 1 0.907
per3 period homolog 3 (Drosophila) 0.903
pax6a paired box gene 6a 0.901
robo3 roundabout homolog 3 0.901
wnt10a wingless-type MMTV integration site family, member 10a 0.898
cdh1 cadherin 1, epithelial 0.898
hhip hedgehog interacting protein 0.895
dkk1b dickkopf 1b 0.894
smad5 MAD homolog 5 (Drosophila) 0.885
pitx3 paired-like homeodomain transcription factor 3 0.884
tbx1 T-box 1 0.881
cmyb transcription factor cmyb 0.876
hoxa9a homeo box A9a 0.876
pax7a paired box gene 7a 0.874
cry1a cryptochrome 1a 0.872
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.867
gli2a GLI-Kruppel family member GLI2a 0.865
pax6b paired box gene 6b 0.862
jag2 jagged 2 0.861
rarab retinoic acid receptor, alpha b 0.855
klf4a Kruppel-like transcription factor 4a 0.853
dlx3b distal-less homeobox gene 3b 0.850
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.849
suv39h1b suppressor of variegation 3-9 homolog 1b 0.848
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.845
cdx4 caudal type homeo box transcription factor 4 0.844
znf703 zinc finger protein 703 0.843
gpia glucose phosphate isomerase a 0.838
ube2i ubiquitin-conjugating enzyme E2I 0.836
wdr36 WD repeat domain 36 0.831
supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.830
rpl36a ribosomal protein L36A 0.828
lhx5 LIM homeobox 5 0.825
dla deltaA 0.825
dcc deleted in colorectal carcinoma 0.819
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.812
notch2 notch homolog 2 0.810
sema3aa semaphorin 3aa 0.805
lamc1 laminin, gamma 1 0.804
hnf1ba HNF1 homeobox Ba 0.801
rad21 RAD21 homolog (S. pombe) 0.800
col2a1a collagen type II, alpha-1a 0.800
pbx4 pre-B-cell leukemia transcription factor 4 0.799
six4b sine oculis homeobox homolog 4b 0.799
dmbx1a diencephalon/mesencephalon homeobox 1a 0.797
neurod neurogenic differentiation 0.789
efnb2a ephrin B2a 0.789
boc brother of CDO 0.787
sall4 sal-like 4 (Drosophila) 0.782
bhlhe22 basic helix-loop-helix family, member e22 0.776
furina furin (paired basic amino acid cleaving enzyme) a 0.773
snai1b snail homolog 1b (Drosophila) 0.773
cadm1b cell adhesion molecule 1b 0.769
robo1 roundabout homolog 1 0.769
klf4 Kruppel-like factor 4 0.764
ihha Indian hedgehog homolog a 0.760
etv5b ets variant 5b 0.756
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism