The network for 'embryonic organ development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic organ development

Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 1.000
mib mind bomb 1.000
cdh2 cadherin 2, neuronal 1.000
shha sonic hedgehog a 1.000
fgf8a fibroblast growth factor 8 a 1.000
foxi1 forkhead box I1 1.000
flh floating head 1.000
bmp2b bone morphogenetic protein 2b 0.999
pax2a paired box gene 2a 0.999
crabp2a cellular retinoic acid binding protein 2, a 0.999
prdm1a PR domain containing 1a, with ZNF domain 0.999
lft2 lefty2 0.999
dlx2a distal-less homeobox gene 2a 0.998
bmp4 bone morphogenetic protein 4 0.998
hand2 heart and neural crest derivatives expressed transcript 2 0.998
tal1 T-cell acute lymphocytic leukemia 1 0.998
gli2a GLI-Kruppel family member GLI2a 0.998
fgf3 fibroblast growth factor 3 0.997
tp53 tumor protein p53 0.997
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.997
sox9a SRY-box containing gene 9a 0.996
sox32 SRY-box containing gene 32 0.995
kdrl kinase insert domain receptor like 0.995
cdon cell adhesion molecule-related/down-regulated by oncogenes 0.995
fn1 fibronectin 1 0.995
gata3 GATA-binding protein 3 0.995
isl1 islet1 0.994
pkd2 polycystic kidney disease 2 0.993
eya1 eyes absent homolog 1 0.993
hnf1ba HNF1 homeobox Ba 0.993
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.992
tfap2a transcription factor AP-2 alpha 0.992
lamb1a laminin, beta 1a 0.992
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.991
twist1a twist1a 0.990
spaw southpaw 0.989
notch1a notch homolog 1a 0.988
notch2 notch homolog 2 0.988
edn1 endothelin 1 0.987
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.987
wnt11 wingless-type MMTV integration site family, member 11 0.986
hoxa2b homeo box A2b 0.985
slit3 slit (Drosophila) homolog 3 0.984
sox1a SRY-box containing gene 1a 0.983
fras1 Fraser syndrome 1 0.982
lef1 lymphocyte enhancer binding factor 1 0.981
irx1a iroquois homeobox protein 1, a 0.981
dlx3b distal-less homeobox gene 3b 0.980
irx1b iroquois homeobox protein 1, b 0.979
myod1 myogenic differentiation 1 0.978
notch3 notch homolog 3 0.977
fbn2b fibrillin 2b 0.976
tp63 tumor protein p63 0.973
gdf6a growth differentiation factor 6a 0.973
hoxd4a homeo box D4a 0.973
six4b sine oculis homeobox homolog 4b 0.973
jag1b jagged 1b 0.973
shhb sonic hedgehog b 0.970
ndr2 nodal-related 2 0.963
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.962
pitx3 paired-like homeodomain transcription factor 3 0.961
foxd3 forkhead box D3 0.961
ptch1 patched 1 0.959
pitx2 paired-like homeodomain transcription factor 2 0.959
gata5 GATA-binding protein 5 0.959
her6 hairy-related 6 0.958
dlx5a distal-less homeobox gene 5a 0.958
disp1 dispatched homolog 1 (Drosophila) 0.958
twist3 twist3 0.957
atoh1a atonal homolog 1a 0.953
hoxb5b homeo box B5b 0.952
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.951
znf703 zinc finger protein 703 0.948
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.948
pax6a paired box gene 6a 0.946
hhex hematopoietically expressed homeobox 0.946
hoxb3a homeo box B3a 0.945
fgfr4 fibroblast growth factor receptor 4 0.944
runx2b runt-related transcription factor 2b 0.943
dkk1b dickkopf 1b 0.940
msxe muscle segment homeobox E 0.937
hoxa3a homeo box A3a 0.936
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.935
mmp2 matrix metalloproteinase 2 0.934
smad5 MAD homolog 5 (Drosophila) 0.933
sox2 SRY-box containing gene 2 0.930
rgma RGM domain family, member A 0.927
tbx16 T-box gene 16 0.925
sema3d semaphorin 3d 0.925
fgfr1a fibroblast growth factor receptor 1a 0.923
tbx18 T-box 18 0.922
bmp2a bone morphogenetic protein 2a 0.921
otop1 otopetrin 1 0.919
col5a2l collagen, type V, alpha 2-like 0.917
smo smoothened homolog (Drosophila) 0.917
hapln1a hyaluronan and proteoglycan link protein 1a 0.914
csad cysteine sulfinic acid decarboxylase 0.912
ccnd1 cyclin D1 0.912
wnt9a wingless-type MMTV integration site family, member 9A 0.912
col27a1a collagen, type XXVII, alpha 1a 0.912
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
unc-73 Protein UNC-73 0.052
egl-18 Protein EGL-18 0.038
trim-9 Protein TRIM-9 0.026
pha-4 Protein PHA-4 0.022
bar-1 Protein BAR-1 0.020
hlh-1 Protein HLH-1 0.018
egl-27 Protein EGL-27 0.014
unc-53 Protein UNC-53 0.014
lin-40 Protein LIN-40 0.013
osm-5 Protein OSM-5 0.013
glp-1 Protein GLP-1 0.011
CELE_Y41E3.11 Protein Y41E3.11 0.011
lin-17 Protein LIN-17 0.011
ceh-32 Protein CEH-32 0.011
mig-6 Protein MIG-6 0.011
lev-1 Protein LEV-1 0.011
hbl-1 Protein HBL-1 0.011
cct-7 Protein CCT-7 0.010
nhr-25 Protein NHR-25 0.010
eor-2 Protein EOR-2 0.010
pry-1 Protein PRY-1 0.010
sma-6 Protein SMA-6 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
wg wingless 0.999
N Notch 0.993
ci cubitus interruptus 0.988
dsh dishevelled 0.979
put punt 0.947
en engrailed 0.930
zfh1 Zn finger homeodomain 1 0.917
htl heartless 0.917
Rac1 CG2248 gene product from transcript CG2248-RA 0.905
Fas2 Fasciclin 2 0.905
tin tinman 0.900
crb crumbs 0.900
sd scalloped 0.893
arm armadillo 0.889
ey eyeless 0.864
emc extra macrochaetae 0.850
Hand CG18144 gene product from transcript CG18144-RA 0.798
Egfr Epidermal growth factor receptor 0.779
LanB2 Laminin B2 0.778
tkv thickveins 0.776
nkd naked cuticle 0.771
Doc2 Dorsocross2 0.749
Mad Mothers against dpp 0.730
robo roundabout 0.712
eya eyes absent 0.709
E(spl) Enhancer of split 0.705
dpp decapentaplegic 0.702
slp1 sloppy paired 1 0.675
rap retina aberrant in pattern 0.667
lea leak 0.638
Ser Serrate 0.631
stumps CG31317 gene product from transcript CG31317-RC 0.580
spi spitz 0.580
fng fringe 0.566
tsh teashirt 0.563
Ubx Ultrabithorax 0.551
mew multiple edematous wings 0.550
ato atonal 0.545
LanB1 CG7123 gene product from transcript CG7123-RA 0.520
so sine oculis 0.481
LanA Laminin A 0.479
Tl Toll 0.467
dac dachshund 0.459
pan pangolin 0.454
dom domino 0.454
Dll Distal-less 0.448
nmo nemo 0.441
ush u-shaped 0.440
Antp Antennapedia 0.437
zip zipper 0.428
Smox Smad on X 0.427
Sra-1 specifically Rac1-associated protein 1 0.427
Ptp69D Protein tyrosine phosphatase 69D 0.422
da daughterless 0.398
phl pole hole 0.388
opa odd paired 0.383
bsk basket 0.378
mam mastermind 0.369
shi shibire 0.364
ara araucan 0.360
kni knirps 0.353
ds dachsous 0.352
ex expanded 0.344
Pvr PDGF- and VEGF-receptor related 0.338
cos costa 0.336
mirr mirror 0.335
babo baboon 0.327
HLHm7 E(spl) region transcript m7 0.315
NetB Netrin-B 0.313
dm diminutive 0.310
Kr Kruppel 0.310
Su(var)2-10 Suppressor of variegation 2-10 0.310
vg vestigial 0.304
bi bifid 0.303
Dfd Deformed 0.296
lin lines 0.292
arr arrow 0.289
L Lobe 0.282
mid midline 0.274
eve even skipped 0.272
fj four-jointed 0.271
baz bazooka 0.256
frc fringe connection 0.247
Tollo CG6890 gene product from transcript CG6890-RA 0.246
gcm glial cells missing 0.244
HLHmbeta E(spl) region transcript mbeta 0.244
Akt1 CG4006 gene product from transcript CG4006-RA 0.243
Optix CG18455 gene product from transcript CG18455-RA 0.236
mys myospheroid 0.233
yki yorkie 0.230
eff effete 0.227
cora coracle 0.226
Su(H) Suppressor of Hairless 0.217
bab2 CG9102 gene product from transcript CG9102-RA 0.215
Pten CG5671 gene product from transcript CG5671-RB 0.211
ttv tout-velu 0.211
vvl ventral veins lacking 0.198
hbs hibris 0.198
Wnt4 Wnt oncogene analog 4 0.188
fas faint sausage 0.186
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Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 0.998
SMAD3 SMAD family member 3 0.990
CREBBP CREB binding protein 0.989
EP300 E1A binding protein p300 0.987
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.957
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.924
SP1 Sp1 transcription factor 0.914
ESR1 estrogen receptor 1 0.908
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.907
TAL1 T-cell acute lymphocytic leukemia 1 0.896
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.868
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.800
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.788
COL1A1 collagen, type I, alpha 1 0.786
SMAD2 SMAD family member 2 0.778
RB1 retinoblastoma 1 0.723
ZFYVE9 zinc finger, FYVE domain containing 9 0.697
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.697
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.686
JAG1 jagged 1 0.681
NOTCH1 notch 1 0.669
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.668
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.642
RXRA retinoid X receptor, alpha 0.628
BMP2 bone morphogenetic protein 2 0.565
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.563
SMAD4 SMAD family member 4 0.553
NCOR1 nuclear receptor corepressor 1 0.529
HOXB5 homeobox B5 0.529
GSK3B glycogen synthase kinase 3 beta 0.529
SKIL SKI-like oncogene 0.517
TCF4 transcription factor 4 0.515
EPAS1 endothelial PAS domain protein 1 0.509
JUN jun proto-oncogene 0.467
RBBP4 retinoblastoma binding protein 4 0.460
RUNX1 runt-related transcription factor 1 0.442
TCF12 transcription factor 12 0.418
PML promyelocytic leukemia 0.409
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.398
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.371
GATA4 GATA binding protein 4 0.351
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.348
NCOA1 nuclear receptor coactivator 1 0.341
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.329
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.312
NRP1 neuropilin 1 0.293
PRKCZ protein kinase C, zeta 0.287
FSTL1 follistatin-like 1 0.277
COL2A1 collagen, type II, alpha 1 0.276
MTA1 metastasis associated 1 0.276
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.272
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.270
COL3A1 collagen, type III, alpha 1 0.266
TNRC6A trinucleotide repeat containing 6A 0.255
ATF2 activating transcription factor 2 0.254
VEGFA vascular endothelial growth factor A 0.239
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.237
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.226
E2F7 E2F transcription factor 7 0.221
CXCL3 chemokine (C-X-C motif) ligand 3 0.211
DAXX death-domain associated protein 0.210
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.209
APC adenomatous polyposis coli 0.198
MTA3 metastasis associated 1 family, member 3 0.194
HOXA11 homeobox A11 0.194
LAMB1 laminin, beta 1 0.194
PIAS1 protein inhibitor of activated STAT, 1 0.192
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.191
SMAD1 SMAD family member 1 0.188
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.182
HIPK2 homeodomain interacting protein kinase 2 0.181
SKI v-ski sarcoma viral oncogene homolog (avian) 0.178
COL4A1 collagen, type IV, alpha 1 0.177
HDAC1 histone deacetylase 1 0.177
ATXN1 ataxin 1 0.175
CTGF connective tissue growth factor 0.171
MYOD1 myogenic differentiation 1 0.170
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.163
HOXB6 homeobox B6 0.155
HOXA5 homeobox A5 0.154
ARNT aryl hydrocarbon receptor nuclear translocator 0.150
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.150
E2F8 E2F transcription factor 8 0.150
COL5A1 collagen, type V, alpha 1 0.150
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.149
CALCA calcitonin-related polypeptide alpha 0.149
TP73 tumor protein p73 0.148
HOXA10 homeobox A10 0.144
KRT18 keratin 18 0.139
WDR5 WD repeat domain 5 0.138
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.138
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.135
NCOR2 nuclear receptor corepressor 2 0.134
HIC1 hypermethylated in cancer 1 0.132
COPA coatomer protein complex, subunit alpha 0.131
TBX5 T-box 5 0.129
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.128
EGR1 early growth response 1 0.124
SOX2 SRY (sex determining region Y)-box 2 0.123
CENPJ centromere protein J 0.123
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism