IMP

Process View

Homo sapiens

27 genes annotated in human

polysaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "polysaccharide biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "polysaccharide biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	0.989
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.988
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.972	Human
GRB10	growth factor receptor-bound protein 10	0.938	Rat
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.879	Human
PRKCZ	protein kinase C, zeta	0.866	Human
IRS1	insulin receptor substrate 1	0.823
IGF1R	insulin-like growth factor 1 receptor	0.698	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.627
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.601
BCL3	B-cell CLL/lymphoma 3	0.547
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.429
NUMB	numb homolog (Drosophila)	0.419
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.365	Human
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.362
HIP1	huntingtin interacting protein 1	0.348
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.344
IRS2	insulin receptor substrate 2	0.317
NRP1	neuropilin 1	0.197
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.183	Human
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.180
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.152
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.127
NOXA1	NADPH oxidase activator 1	0.123
LZTS2	leucine zipper, putative tumor suppressor 2	0.106
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.097
STAT5B	signal transducer and activator of transcription 5B	0.095
THBS1	thrombospondin 1	0.093
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.092
IGF2R	insulin-like growth factor 2 receptor	0.089
LAT	linker for activation of T cells	0.089
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.088	Human
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.087
ENG	endoglin	0.085
SH2B1	SH2B adaptor protein 1	0.074
TOM1L1	target of myb1 (chicken)-like 1	0.071
ITGB1BP3	integrin beta 1 binding protein 3	0.070
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.069	Human
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.066
PRKCB	protein kinase C, beta	0.062
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.056
CNTF	ciliary neurotrophic factor	0.053
LRRK2	leucine-rich repeat kinase 2	0.053
RAB6A	RAB6A, member RAS oncogene family	0.051
PICK1	protein interacting with PRKCA 1	0.050
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.050
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.048
FAF1	Fas (TNFRSF6) associated factor 1	0.048
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.046
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.045
FSTL1	follistatin-like 1	0.044
SH3RF1	SH3 domain containing ring finger 1	0.044
TNIP2	TNFAIP3 interacting protein 2	0.039
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.038
RAB5A	RAB5A, member RAS oncogene family	0.037
OCRL	oculocerebrorenal syndrome of Lowe	0.036	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.035
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.035
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.035
DCAF7	DDB1 and CUL4 associated factor 7	0.034
HIPK2	homeodomain interacting protein kinase 2	0.034
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.033
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.033
EGFR	epidermal growth factor receptor	0.033
MAPT	microtubule-associated protein tau	0.033
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.033
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.032
LDLR	low density lipoprotein receptor	0.030
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.028
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.028
RPTOR	regulatory associated protein of MTOR, complex 1	0.027
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.026
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.026
SESN2	sestrin 2	0.025
INPPL1	inositol polyphosphate phosphatase-like 1	0.023
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.022
NMT2	N-myristoyltransferase 2	0.022
CAPRIN2	caprin family member 2	0.022
CDCP1	CUB domain containing protein 1	0.022
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.022
RAB14	RAB14, member RAS oncogene family	0.021
COL6A1	collagen, type VI, alpha 1	0.021
EPS15	epidermal growth factor receptor pathway substrate 15	0.021
SORBS2	sorbin and SH3 domain containing 2	0.021
PTPRB	protein tyrosine phosphatase, receptor type, B	0.020
PRKCA	protein kinase C, alpha	0.020
OSBP	oxysterol binding protein	0.019
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.019
CUX1	cut-like homeobox 1	0.018
GCKR	glucokinase (hexokinase 4) regulator	0.018
COL5A1	collagen, type V, alpha 1	0.018
DCTN1	dynactin 1	0.018
PFKL	phosphofructokinase, liver	0.017
PPID	peptidylprolyl isomerase D	0.017
NCF1	neutrophil cytosolic factor 1	0.017
A2M	alpha-2-macroglobulin	0.016
GRB14	growth factor receptor-bound protein 14	0.016
COL4A2	collagen, type IV, alpha 2	0.016
PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	0.016
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.016
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.016
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.016
PFDN1	prefoldin subunit 1	0.016
PGK1	phosphoglycerate kinase 1	0.015
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.015
PPP1R3F	protein phosphatase 1, regulatory (inhibitor) subunit 3F	0.015
CD2	CD2 molecule	0.015
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.015
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.014
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.014
GSK3B	glycogen synthase kinase 3 beta	0.014
GYG2	glycogenin 2	0.014	Yeast
TNK2	tyrosine kinase, non-receptor, 2	0.014
SMAD9	SMAD family member 9	0.014
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.014
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.013
FAM117B	family with sequence similarity 117, member B	0.013
COL4A1	collagen, type IV, alpha 1	0.013
CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	0.013
COL2A1	collagen, type II, alpha 1	0.013
ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	0.013
BAD	BCL2-associated agonist of cell death	0.013
SORBS3	sorbin and SH3 domain containing 3	0.013
CCND1	cyclin D1	0.013
AKT1S1	AKT1 substrate 1 (proline-rich)	0.013
IGFBP5	insulin-like growth factor binding protein 5	0.013
ISOC1	isochorismatase domain containing 1	0.012
PLCG1	phospholipase C, gamma 1	0.012
EPOR	erythropoietin receptor	0.012
TGFB3	transforming growth factor, beta 3	0.012
STC1	stanniocalcin 1	0.012
TGFBR1	transforming growth factor, beta receptor 1	0.012
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.012
PID1	phosphotyrosine interaction domain containing 1	0.012
GYS2	glycogen synthase 2 (liver)	0.012
ZNF746	zinc finger protein 746	0.012
GLTPD1	glycolipid transfer protein domain containing 1	0.012
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.012
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.012
TRIM9	tripartite motif containing 9	0.012
WNT3A	wingless-type MMTV integration site family, member 3A	0.012
CCL14	chemokine (C-C motif) ligand 14	0.012
BCL2	B-cell CLL/lymphoma 2	0.012
CSK	c-src tyrosine kinase	0.011
RAB8A	RAB8A, member RAS oncogene family	0.011
ARRB1	arrestin, beta 1	0.011
FOXO3	forkhead box O3	0.011
CD33	CD33 molecule	0.011
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.011
IL4R	interleukin 4 receptor	0.011
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.011
ACVR2B	activin A receptor, type IIB	0.011
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.011
MBL2	mannose-binding lectin (protein C) 2, soluble	0.011
CCHCR1	coiled-coil alpha-helical rod protein 1	0.011
DEPTOR	DEP domain containing MTOR-interacting protein	0.011
HTT	huntingtin	0.010
FGFR1	fibroblast growth factor receptor 1	0.010
ARRB2	arrestin, beta 2	0.010
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.010
CYBA	cytochrome b-245, alpha polypeptide	0.010
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.010
PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	0.010
COL1A2	collagen, type I, alpha 2	0.010
CLTCL1	clathrin, heavy chain-like 1	0.010
CAV1	caveolin 1, caveolae protein, 22kDa	0.010
POFUT1	protein O-fucosyltransferase 1	0.010
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.010
BMP1	bone morphogenetic protein 1	0.010
BMX	BMX non-receptor tyrosine kinase	0.010
GMCL1	germ cell-less homolog 1 (Drosophila)	0.010