IMP

Process View

Homo sapiens

3 genes annotated in human

regulation of glomerulus development

Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of glomerulus development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of glomerulus development" (in gray)

Name	Description	Probability	Func Analog Organism
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	1.000
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	1.000
NRP1	neuropilin 1	1.000
VEGFA	vascular endothelial growth factor A	1.000	Human
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	1.000
BMPR1A	bone morphogenetic protein receptor, type IA	0.999
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.997
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.993
PGF	placental growth factor	0.988	Human
FSTL1	follistatin-like 1	0.968
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.954
BMPR1B	bone morphogenetic protein receptor, type IB	0.927
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.856
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.833
NOG	noggin	0.829	Mouse
PDGFA	platelet-derived growth factor alpha polypeptide	0.770	Human
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.751
TIMP3	TIMP metallopeptidase inhibitor 3	0.715
COL2A1	collagen, type II, alpha 1	0.667
BMP2	bone morphogenetic protein 2	0.589	Human
BMP7	bone morphogenetic protein 7	0.560
PTPRB	protein tyrosine phosphatase, receptor type, B	0.472
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.434
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.380
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.375
PDGFC	platelet derived growth factor C	0.353
COL6A1	collagen, type VI, alpha 1	0.352
PLCG1	phospholipase C, gamma 1	0.342
SNAI1	snail homolog 1 (Drosophila)	0.335
COL5A1	collagen, type V, alpha 1	0.278
STC1	stanniocalcin 1	0.244
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.217
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.195
EGR3	early growth response 3	0.195
EGR2	early growth response 2	0.180
LDLR	low density lipoprotein receptor	0.147
COL1A1	collagen, type I, alpha 1	0.125
COL4A1	collagen, type IV, alpha 1	0.124
SPRY4	sprouty homolog 4 (Drosophila)	0.106
TGFB2	transforming growth factor, beta 2	0.096
TAOK1	TAO kinase 1	0.095
BBS1	Bardet-Biedl syndrome 1	0.089
THBS1	thrombospondin 1	0.082
BHLHE40	basic helix-loop-helix family, member e40	0.080
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.074
IER2	immediate early response 2	0.073
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.069
FST	follistatin	0.066
FOXF1	forkhead box F1	0.057
CDH5	cadherin 5, type 2 (vascular endothelium)	0.054
DDIT4	DNA-damage-inducible transcript 4	0.053
BMP4	bone morphogenetic protein 4	0.053
FZD4	frizzled homolog 4 (Drosophila)	0.047
COL4A2	collagen, type IV, alpha 2	0.046
JUNB	jun B proto-oncogene	0.045
STC2	stanniocalcin 2	0.042
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.041
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.036
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.035
ZNF205	zinc finger protein 205	0.035
EFNB3	ephrin-B3	0.034
ZFYVE9	zinc finger, FYVE domain containing 9	0.033
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.033
VEGFC	vascular endothelial growth factor C	0.033	Human
NRP2	neuropilin 2	0.032
MDFI	MyoD family inhibitor	0.032
CAV1	caveolin 1, caveolae protein, 22kDa	0.031
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.029
FLT4	fms-related tyrosine kinase 4	0.029
WNT2	wingless-type MMTV integration site family member 2	0.029
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.029
LOXL2	lysyl oxidase-like 2	0.026
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.026
HAND1	heart and neural crest derivatives expressed 1	0.026
BMP8B	bone morphogenetic protein 8b	0.024	Human
BMP6	bone morphogenetic protein 6	0.024	Human
BBS4	Bardet-Biedl syndrome 4	0.024
DUSP6	dual specificity phosphatase 6	0.023
INHBB	inhibin, beta B	0.023
TBX2	T-box 2	0.023
WT1	Wilms tumor 1	0.023	Mouse
TGFB3	transforming growth factor, beta 3	0.022
HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	0.022
EPAS1	endothelial PAS domain protein 1	0.022
GFRA1	GDNF family receptor alpha 1	0.022
NPM3	nucleophosmin/nucleoplasmin 3	0.021
FOXF2	forkhead box F2	0.021
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.021
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.020
SLC2A4RG	SLC2A4 regulator	0.020
COL13A1	collagen, type XIII, alpha 1	0.020
SLIT2	slit homolog 2 (Drosophila)	0.020
RGS16	regulator of G-protein signaling 16	0.020
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.019
SOX2	SRY (sex determining region Y)-box 2	0.019
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.019
TAL1	T-cell acute lymphocytic leukemia 1	0.019
EDN1	endothelin 1	0.019
GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)	0.019
ANGPT2	angiopoietin 2	0.018
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.018
DDIT3	DNA-damage-inducible transcript 3	0.018
PTHLH	parathyroid hormone-like hormone	0.018
HAS2	hyaluronan synthase 2	0.018
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.017
BBS2	Bardet-Biedl syndrome 2	0.017
BMP3	bone morphogenetic protein 3	0.017	Human
SOX11	SRY (sex determining region Y)-box 11	0.017
TG	thyroglobulin	0.017
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.017
CEP164	centrosomal protein 164kDa	0.017
HSPG2	heparan sulfate proteoglycan 2	0.017
AES	amino-terminal enhancer of split	0.017
IL11	interleukin 11	0.017
BBS7	Bardet-Biedl syndrome 7	0.017
TEK	TEK tyrosine kinase, endothelial	0.016
NXPH3	neurexophilin 3	0.016
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.016
ADCY1	adenylate cyclase 1 (brain)	0.016
IGFBP5	insulin-like growth factor binding protein 5	0.016
PITX2	paired-like homeodomain 2	0.016
VLDLR	very low density lipoprotein receptor	0.016
G0S2	G0/G1switch 2	0.016
MMP19	matrix metallopeptidase 19	0.016
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.016
GDNF	glial cell derived neurotrophic factor	0.016
EGFR	epidermal growth factor receptor	0.015
FZD10	frizzled homolog 10 (Drosophila)	0.015
PRPH	peripherin	0.015
F3	coagulation factor III (thromboplastin, tissue factor)	0.015
GPR50	G protein-coupled receptor 50	0.015
COL1A2	collagen, type I, alpha 2	0.015
SMAD3	SMAD family member 3	0.015
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.015
BMP8A	bone morphogenetic protein 8a	0.014	Human
HIPK2	homeodomain interacting protein kinase 2	0.014
PKN1	protein kinase N1	0.014
OSMR	oncostatin M receptor	0.014
SOSTDC1	sclerostin domain containing 1	0.014
P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	0.014
FGF4	fibroblast growth factor 4	0.014
EXT1	exostosin 1	0.014
BTBD2	BTB (POZ) domain containing 2	0.014
FZD8	frizzled homolog 8 (Drosophila)	0.013
ZNF420	zinc finger protein 420	0.013
HMGA2	high mobility group AT-hook 2	0.013
SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	0.013
GAS1	growth arrest-specific 1	0.013
WNT4	wingless-type MMTV integration site family, member 4	0.013
WNT11	wingless-type MMTV integration site family, member 11	0.013
CLSTN2	calsyntenin 2	0.013
FIGF	c-fos induced growth factor (vascular endothelial growth factor D)	0.013	Human
CDK6	cyclin-dependent kinase 6	0.013
PTX3	pentraxin 3, long	0.013
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.013
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.013
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.013
GTPBP2	GTP binding protein 2	0.013
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.013
GPC3	glypican 3	0.013
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.013
SOX21	SRY (sex determining region Y)-box 21	0.013
COL4A6	collagen, type IV, alpha 6	0.012
HOXC10	homeobox C10	0.012
SH2B2	SH2B adaptor protein 2	0.012
RELN	reelin	0.012
CA9	carbonic anhydrase IX	0.012
ENPEP	glutamyl aminopeptidase (aminopeptidase A)	0.012
ART4	ADP-ribosyltransferase 4 (Dombrock blood group)	0.012
SOX18	SRY (sex determining region Y)-box 18	0.012
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.012
INSR	insulin receptor	0.012
UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.012
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.012
PRRX1	paired related homeobox 1	0.012
EFNB2	ephrin-B2	0.012
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.012
JAG1	jagged 1	0.012
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.012
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.012
MN1	meningioma (disrupted in balanced translocation) 1	0.012
ERRFI1	ERBB receptor feedback inhibitor 1	0.012
TFPI2	tissue factor pathway inhibitor 2	0.012
CYR61	cysteine-rich, angiogenic inducer, 61	0.012
MAPK8	mitogen-activated protein kinase 8	0.012
NFYA	nuclear transcription factor Y, alpha	0.012
PTCH1	patched 1	0.012
TWIST1	twist homolog 1 (Drosophila)	0.011
ACAN	aggrecan	0.011
RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.011
DLK1	delta-like 1 homolog (Drosophila)	0.011
HOXD10	homeobox D10	0.011
HOXD11	homeobox D11	0.011
PSG9	pregnancy specific beta-1-glycoprotein 9	0.011
NOS1	nitric oxide synthase 1 (neuronal)	0.011
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.011
YBX2	Y box binding protein 2	0.011
NDRG1	N-myc downstream regulated 1	0.011
PRPH2	peripherin 2 (retinal degeneration, slow)	0.011
DLX5	distal-less homeobox 5	0.011
NPY5R	neuropeptide Y receptor Y5	0.011
FGF18	fibroblast growth factor 18	0.011
CBX2	chromobox homolog 2	0.011
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.011
PLXDC1	plexin domain containing 1	0.011
NPPC	natriuretic peptide C	0.011
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011
CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	0.011
TBX3	T-box 3	0.011
GJD2	gap junction protein, delta 2, 36kDa	0.011
USF2	upstream transcription factor 2, c-fos interacting	0.011
EYA1	eyes absent homolog 1 (Drosophila)	0.011
CD34	CD34 molecule	0.011
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.011
PRRX2	paired related homeobox 2	0.011
LGALS13	lectin, galactoside-binding, soluble, 13	0.011
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.011
SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)	0.011
CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1	0.011
NODAL	nodal homolog (mouse)	0.011	Human
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.011
HOXB5	homeobox B5	0.010
SALL2	sal-like 2 (Drosophila)	0.010
HHIPL2	HHIP-like 2	0.010
ACVR2B	activin A receptor, type IIB	0.010
TSHB	thyroid stimulating hormone, beta	0.010
SRPX	sushi-repeat containing protein, X-linked	0.010
CARD10	caspase recruitment domain family, member 10	0.010
HOXC5	homeobox C5	0.010
AVPR1A	arginine vasopressin receptor 1A	0.010
AR	androgen receptor	0.010
PLAT	plasminogen activator, tissue	0.010
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.010
USP42	ubiquitin specific peptidase 42	0.010
NKX3-2	NK3 homeobox 2	0.010
NTN1	netrin 1	0.010
INHBA	inhibin, beta A	0.010
SCUBE3	signal peptide, CUB domain, EGF-like 3	0.010
KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4	0.010
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.010
ULBP2	UL16 binding protein 2	0.010
WNT1	wingless-type MMTV integration site family, member 1	0.010
PRKG1	protein kinase, cGMP-dependent, type I	0.010
MYST1	MYST histone acetyltransferase 1	0.010
TGFB1	transforming growth factor, beta 1	0.010
ALDOB	aldolase B, fructose-bisphosphate	0.010
CER1	cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)	0.010
ADAM18	ADAM metallopeptidase domain 18	0.010
EN2	engrailed homeobox 2	0.010
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.010
PAX7	paired box 7	0.010