IMP

Process View

Homo sapiens

1 genes annotated in human

ectodermal placode morphogenesis

The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ectodermal placode morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ectodermal placode morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
ARRB1	arrestin, beta 1	0.874
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.606
VEGFA	vascular endothelial growth factor A	0.304
SP1	Sp1 transcription factor	0.212
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.183
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.139
FGFR1	fibroblast growth factor receptor 1	0.138	Zebrafish
GSK3B	glycogen synthase kinase 3 beta	0.131
BMP1	bone morphogenetic protein 1	0.107
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.106
NKX2-1	NK2 homeobox 1	0.096
POU5F1	POU class 5 homeobox 1	0.081
HNF4A	hepatocyte nuclear factor 4, alpha	0.068
SMAD1	SMAD family member 1	0.067
HCFC1	host cell factor C1 (VP16-accessory protein)	0.062
FOXD3	forkhead box D3	0.062
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.054
MSX2	msh homeobox 2	0.052
SALL2	sal-like 2 (Drosophila)	0.049
SREBF2	sterol regulatory element binding transcription factor 2	0.048
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.045
SH3BP4	SH3-domain binding protein 4	0.044
FGF2	fibroblast growth factor 2 (basic)	0.044
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.042
FSTL1	follistatin-like 1	0.042
LRRK2	leucine-rich repeat kinase 2	0.042
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.040
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.040
HNF1A	HNF1 homeobox A	0.038
KCTD1	potassium channel tetramerisation domain containing 1	0.037
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.036
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.036
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.035
MDFI	MyoD family inhibitor	0.033
CXCR5	chemokine (C-X-C motif) receptor 5	0.033
FRS2	fibroblast growth factor receptor substrate 2	0.032	Mouse
AXIN2	axin 2	0.031
FGF1	fibroblast growth factor 1 (acidic)	0.030
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.030
CDV3	CDV3 homolog (mouse)	0.029
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.028
NCF2	neutrophil cytosolic factor 2	0.026
TCF4	transcription factor 4	0.025
RGS19	regulator of G-protein signaling 19	0.024
EDAR	ectodysplasin A receptor	0.024
ATN1	atrophin 1	0.024
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.024
NCF1	neutrophil cytosolic factor 1	0.023
SMAD4	SMAD family member 4	0.023
NUCB1	nucleobindin 1	0.023
APC	adenomatous polyposis coli	0.023
GLIS2	GLIS family zinc finger 2	0.023
HRG	histidine-rich glycoprotein	0.023
PGF	placental growth factor	0.022
NCF4	neutrophil cytosolic factor 4, 40kDa	0.022
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.022
CYBA	cytochrome b-245, alpha polypeptide	0.022
FGFR3	fibroblast growth factor receptor 3	0.022
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.021
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.021
PML	promyelocytic leukemia	0.021
YY1	YY1 transcription factor	0.021
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.021
LRP6	low density lipoprotein receptor-related protein 6	0.020	Mouse
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.020
MEST	mesoderm specific transcript homolog (mouse)	0.020
ZBTB17	zinc finger and BTB domain containing 17	0.019
MT1A	metallothionein 1A	0.019
GATAD2A	GATA zinc finger domain containing 2A	0.018
NOSTRIN	nitric oxide synthase trafficker	0.018
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.018
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.018
HEMGN	hemogen	0.018
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.018
GAB2	GRB2-associated binding protein 2	0.018
CHD4	chromodomain helicase DNA binding protein 4	0.018
ACTN4	actinin, alpha 4	0.018
AXIN1	axin 1	0.018	Zebrafish
DLX2	distal-less homeobox 2	0.017
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.017
ANKRD13A	ankyrin repeat domain 13A	0.017
COL2A1	collagen, type II, alpha 1	0.017
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.017
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.017
RCOR1	REST corepressor 1	0.017
PPT1	palmitoyl-protein thioesterase 1	0.016
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.016
MBD2	methyl-CpG binding domain protein 2	0.016
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.016
GSK3A	glycogen synthase kinase 3 alpha	0.016
CAPNS1	calpain, small subunit 1	0.016
DCTN2	dynactin 2 (p50)	0.016
KLF5	Kruppel-like factor 5 (intestinal)	0.016
CTBP2	C-terminal binding protein 2	0.015
GATAD2B	GATA zinc finger domain containing 2B	0.015
DLX5	distal-less homeobox 5	0.015	Zebrafish
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.015
PAX6	paired box 6	0.015
TBX2	T-box 2	0.015
LHX2	LIM homeobox 2	0.015
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.015
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.015
FOXC1	forkhead box C1	0.014
MSX1	msh homeobox 1	0.014	Zebrafish
SIM2	single-minded homolog 2 (Drosophila)	0.014
MTA3	metastasis associated 1 family, member 3	0.014
NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	0.014
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.014
BIN1	bridging integrator 1	0.014
SAP30	Sin3A-associated protein, 30kDa	0.014
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.014
HMGA1	high mobility group AT-hook 1	0.014
PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	0.014
FOXA2	forkhead box A2	0.014
TGIF1	TGFB-induced factor homeobox 1	0.014
PAK7	p21 protein (Cdc42/Rac)-activated kinase 7	0.014
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.014
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.014
FGFR2	fibroblast growth factor receptor 2	0.014
RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	0.014
ZMYND8	zinc finger, MYND-type containing 8	0.014
CUX1	cut-like homeobox 1	0.014
HOXC8	homeobox C8	0.014
CRHR1	corticotropin releasing hormone receptor 1	0.014
EYA2	eyes absent homolog 2 (Drosophila)	0.014	Fly
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.014
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.014
EYA1	eyes absent homolog 1 (Drosophila)	0.013
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.013
HSPG2	heparan sulfate proteoglycan 2	0.013
TGFBR1	transforming growth factor, beta receptor 1	0.013
SHB	Src homology 2 domain containing adaptor protein B	0.013
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.013
RHOG	ras homolog gene family, member G (rho G)	0.013
NFIB	nuclear factor I/B	0.013
FAM123B	family with sequence similarity 123B	0.013
RGS14	regulator of G-protein signaling 14	0.013
BANP	BTG3 associated nuclear protein	0.013
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.013	Mouse
NT5C3	5'-nucleotidase, cytosolic III	0.013
HOXB9	homeobox B9	0.013
TGFB1	transforming growth factor, beta 1	0.013
WNT3A	wingless-type MMTV integration site family, member 3A	0.013
CDH5	cadherin 5, type 2 (vascular endothelium)	0.013
MAX	MYC associated factor X	0.013
LYPD3	LY6/PLAUR domain containing 3	0.013
FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.012
RUNX2	runt-related transcription factor 2	0.012
TGFB3	transforming growth factor, beta 3	0.012
MBD3	methyl-CpG binding domain protein 3	0.012
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.012
RND3	Rho family GTPase 3	0.012
GNG2	guanine nucleotide binding protein (G protein), gamma 2	0.012
EMD	emerin	0.012
SIX2	SIX homeobox 2	0.012	Fly
RGS5	regulator of G-protein signaling 5	0.012
CADM4	cell adhesion molecule 4	0.012
HNF1B	HNF1 homeobox B	0.012	Zebrafish
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.012
ONECUT2	one cut homeobox 2	0.012
WNT11	wingless-type MMTV integration site family, member 11	0.012
GIGYF1	GRB10 interacting GYF protein 1	0.012
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	0.012
FOXD1	forkhead box D1	0.012
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
ZNF410	zinc finger protein 410	0.012
OVOL1	ovo-like 1(Drosophila)	0.012
BZW1	basic leucine zipper and W2 domains 1	0.012
HOXC13	homeobox C13	0.012
ZFPM1	zinc finger protein, multitype 1	0.012
CNN2	calponin 2	0.012
MECOM	MDS1 and EVI1 complex locus	0.012
PSEN1	presenilin 1	0.012
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.012
TAL1	T-cell acute lymphocytic leukemia 1	0.012
PAX2	paired box 2	0.012
SMAD7	SMAD family member 7	0.012
ANUBL1	AN1, ubiquitin-like, homolog (Xenopus laevis)	0.011
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.011
CRMP1	collapsin response mediator protein 1	0.011
SOX1	SRY (sex determining region Y)-box 1	0.011
SOX13	SRY (sex determining region Y)-box 13	0.011
PELP1	proline, glutamate and leucine rich protein 1	0.011
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.011
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.011
TRIM9	tripartite motif containing 9	0.011
BAIAP2	BAI1-associated protein 2	0.011
PLCG1	phospholipase C, gamma 1	0.011
SOX7	SRY (sex determining region Y)-box 7	0.011
NCOA6	nuclear receptor coactivator 6	0.011
RAP1B	RAP1B, member of RAS oncogene family	0.011
S1PR1	sphingosine-1-phosphate receptor 1	0.011
GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.011
DDIT4	DNA-damage-inducible transcript 4	0.011
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.011
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.011
EN1	engrailed homeobox 1	0.011
FGF18	fibroblast growth factor 18	0.011
PROX1	prospero homeobox 1	0.011	Mouse
PURA	purine-rich element binding protein A	0.011
MCC	mutated in colorectal cancers	0.011
HOXC6	homeobox C6	0.011
LAMA5	laminin, alpha 5	0.011
SALL1	sal-like 1 (Drosophila)	0.011
DLX3	distal-less homeobox 3	0.011	Zebrafish
RYR2	ryanodine receptor 2 (cardiac)	0.011
FBXL18	F-box and leucine-rich repeat protein 18	0.011
FAM110C	family with sequence similarity 110, member C	0.011
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.011
PYY	peptide YY	0.011
FOXG1	forkhead box G1	0.011
SNAI1	snail homolog 1 (Drosophila)	0.011
BTRC	beta-transducin repeat containing	0.011
MAP2K5	mitogen-activated protein kinase kinase 5	0.011
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.011
FAM110A	family with sequence similarity 110, member A	0.011
PITPNB	phosphatidylinositol transfer protein, beta	0.011
HOXB8	homeobox B8	0.011
BNC1	basonuclin 1	0.011
TNPO1	transportin 1	0.011
ACVR2B	activin A receptor, type IIB	0.011
HOXA11	homeobox A11	0.011
HIC1	hypermethylated in cancer 1	0.011
IRX5	iroquois homeobox 5	0.011
RAB6B	RAB6B, member RAS oncogene family	0.011
EZR	ezrin	0.011
TBX3	T-box 3	0.011	Mouse
FBLN1	fibulin 1	0.011
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.011	Zebrafish
ATF7IP	activating transcription factor 7 interacting protein	0.011
NCKIPSD	NCK interacting protein with SH3 domain	0.010
SIX4	SIX homeobox 4	0.010	Mouse
NKX3-2	NK3 homeobox 2	0.010
GPR50	G protein-coupled receptor 50	0.010
HOXC9	homeobox C9	0.010
HOXD9	homeobox D9	0.010
AFF3	AF4/FMR2 family, member 3	0.010
FABP7	fatty acid binding protein 7, brain	0.010
CCNH	cyclin H	0.010
CXXC5	CXXC finger protein 5	0.010
MTMR10	myotubularin related protein 10	0.010
RELN	reelin	0.010
HES1	hairy and enhancer of split 1, (Drosophila)	0.010
PTK7	PTK7 protein tyrosine kinase 7	0.010
DUSP4	dual specificity phosphatase 4	0.010
RUNX1	runt-related transcription factor 1	0.010
C8orf48	chromosome 8 open reading frame 48	0.010
STC1	stanniocalcin 1	0.010
F2R	coagulation factor II (thrombin) receptor	0.010
TBX1	T-box 1	0.010
LTBP4	latent transforming growth factor beta binding protein 4	0.010
GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa	0.010
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.010
GDI2	GDP dissociation inhibitor 2	0.010
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.010
FGD1	FYVE, RhoGEF and PH domain containing 1	0.010
VIL1	villin 1	0.010
MTA2	metastasis associated 1 family, member 2	0.010
FRK	fyn-related kinase	0.010
HOXC10	homeobox C10	0.010
HOXD11	homeobox D11	0.010
BMP7	bone morphogenetic protein 7	0.010
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.010
EFNB1	ephrin-B1	0.010
THAP11	THAP domain containing 11	0.010
GATA2	GATA binding protein 2	0.010
ZBTB7A	zinc finger and BTB domain containing 7A	0.010
MIER1	mesoderm induction early response 1 homolog (Xenopus laevis)	0.010
ARL3	ADP-ribosylation factor-like 3	0.010