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Process View

Mus musculus

10 genes annotated in mouse

renal filtration cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal filtration cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal filtration cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.995
Fgfr2	fibroblast growth factor receptor 2	0.981	Fly
Pax2	paired box gene 2	0.976
Gli3	GLI-Kruppel family member GLI3	0.960
C1qc	complement component 1, q subcomponent, C chain	0.932	Mouse
Jag1	jagged 1	0.896
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.834	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.749
Foxa2	forkhead box A2	0.703	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.701
Lamc1	laminin, gamma 1	0.690	Mouse
Foxc2	forkhead box C2	0.671
Fos	FBJ osteosarcoma oncogene	0.644
Nphs2	nephrosis 2 homolog, podocin (human)	0.624
Tyrobp	TYRO protein tyrosine kinase binding protein	0.624
Bmp4	bone morphogenetic protein 4	0.606
Foxc1	forkhead box C1	0.581	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.569
C1qb	complement component 1, q subcomponent, beta polypeptide	0.556	Mouse
Pax8	paired box gene 8	0.519
Lhx1	LIM homeobox protein 1	0.512
Tgfb2	transforming growth factor, beta 2	0.512
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.502
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.440
Tcfap2a	transcription factor AP-2, alpha	0.431
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.390
Hoxa1	homeobox A1	0.387
Hmx3	H6 homeobox 3	0.379
Tbx1	T-box 1	0.359
Pitx2	paired-like homeodomain transcription factor 2	0.352
Emx2	empty spiracles homolog 2 (Drosophila)	0.332
Wt1	Wilms tumor 1 homolog	0.328
Jun	Jun oncogene	0.328
Lama5	laminin, alpha 5	0.313
Dlx5	distal-less homeobox 5	0.304
Sox2	SRY-box containing gene 2	0.294
Rarg	retinoic acid receptor, gamma	0.292
Klf4	Kruppel-like factor 4 (gut)	0.277	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.273
Gdnf	glial cell line derived neurotrophic factor	0.271
Vegfa	vascular endothelial growth factor A	0.271
Notch2	Notch gene homolog 2 (Drosophila)	0.241
Egr1	early growth response 1	0.227	Mouse
Lyz2	lysozyme 2	0.219
Dusp1	dual specificity phosphatase 1	0.214
Fgf8	fibroblast growth factor 8	0.212
Col4a3	collagen, type IV, alpha 3	0.187
Efnb2	ephrin B2	0.183
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.180
Otx1	orthodenticle homolog 1 (Drosophila)	0.172
Ly86	lymphocyte antigen 86	0.170
Nos3	nitric oxide synthase 3, endothelial cell	0.164
Csf1r	colony stimulating factor 1 receptor	0.162
Tbx10	T-box 10	0.145
Apoe	apolipoprotein E	0.134
Psen1	presenilin 1	0.131
Alx4	aristaless-like homeobox 4	0.131
Cd151	CD151 antigen	0.128
Frmd6	FERM domain containing 6	0.123
Eya1	eyes absent 1 homolog (Drosophila)	0.121
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.120
Ptgs2	prostaglandin-endoperoxide synthase 2	0.114
Aif1	allograft inflammatory factor 1	0.112
Dll1	delta-like 1 (Drosophila)	0.108
Btg2	B-cell translocation gene 2, anti-proliferative	0.105
Lmx1a	LIM homeobox transcription factor 1 alpha	0.105
Col4a1	collagen, type IV, alpha 1	0.103
Fgfr1	fibroblast growth factor receptor 1	0.102	Fly
Pax6	paired box gene 6	0.101
Lepr	leptin receptor	0.101
Ctnnb1	catenin (cadherin associated protein), beta 1	0.100
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.095
Foxa1	forkhead box A1	0.095	Mouse
Ctss	cathepsin S	0.094
Pou5f1	POU domain, class 5, transcription factor 1	0.092
Vangl2	vang-like 2 (van gogh, Drosophila)	0.084
Lmx1b	LIM homeobox transcription factor 1 beta	0.083
Rxra	retinoid X receptor alpha	0.083
Chrd	chordin	0.082
Gbx2	gastrulation brain homeobox 2	0.082
Klf6	Kruppel-like factor 6	0.080	Mouse
Nid1	nidogen 1	0.079
Zic3	zinc finger protein of the cerebellum 3	0.079
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.078
Matn3	matrilin 3	0.077
Csf1	colony stimulating factor 1 (macrophage)	0.076
Cdh5	cadherin 5	0.075
Nodal	nodal	0.075
Egfr	epidermal growth factor receptor	0.073
Hoxa2	homeobox A2	0.073
Klf2	Kruppel-like factor 2 (lung)	0.072	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.071
Msx1	homeobox, msh-like 1	0.068
Nog	noggin	0.067
Junb	Jun-B oncogene	0.065
Sox9	SRY-box containing gene 9	0.062
Gucy2e	guanylate cyclase 2e	0.062
Ush1g	Usher syndrome 1G homolog (human)	0.062
En1	engrailed 1	0.058
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.058
Notch1	Notch gene homolog 1 (Drosophila)	0.058	Mouse
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.057
Klf7	Kruppel-like factor 7 (ubiquitous)	0.056	Mouse
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.056
Gdf3	growth differentiation factor 3	0.053	Mouse Fly
Cdx1	caudal type homeobox 1	0.053
Rhob	ras homolog gene family, member B	0.053
Nkx2-1	NK2 homeobox 1	0.051
Insm1	insulinoma-associated 1	0.050
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.049
Dll4	delta-like 4 (Drosophila)	0.047
Pax3	paired box gene 3	0.047
Runx2	runt related transcription factor 2	0.046
Ihh	Indian hedgehog	0.041
Myo15	myosin XV	0.040
Ret	ret proto-oncogene	0.039
Pbx1	pre B-cell leukemia transcription factor 1	0.038
Hoxd13	homeobox D13	0.036
Foxh1	forkhead box H1	0.034
Hand1	heart and neural crest derivatives expressed transcript 1	0.033
Col4a4	collagen, type IV, alpha 4	0.033
Ar	androgen receptor	0.033
Lmna	lamin A	0.032
Hes1	hairy and enhancer of split 1 (Drosophila)	0.032
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.031
Egr2	early growth response 2	0.031	Mouse
Cyr61	cysteine rich protein 61	0.031
Ahr	aryl-hydrocarbon receptor	0.030
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.030
Zic2	zinc finger protein of the cerebellum 2	0.030
Pou4f2	POU domain, class 4, transcription factor 2	0.029
Ntn4	netrin 4	0.029	Mouse
Hoxd11	homeobox D11	0.029
Bmp7	bone morphogenetic protein 7	0.028
Epor	erythropoietin receptor	0.028
Lrp1	low density lipoprotein receptor-related protein 1	0.027
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.027
Bdnf	brain derived neurotrophic factor	0.027
Myo6	myosin VI	0.027
Hmx1	H6 homeobox 1	0.026
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.025
Etv2	ets variant gene 2	0.025
Ptf1a	pancreas specific transcription factor, 1a	0.024
Hoxa9	homeobox A9	0.024
Nab2	Ngfi-A binding protein 2	0.023
Psen2	presenilin 2	0.023
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.023
Timp3	tissue inhibitor of metalloproteinase 3	0.023
Foxd4	forkhead box D4	0.022	Mouse
Rarb	retinoic acid receptor, beta	0.021
Wnt9b	wingless-type MMTV integration site 9B	0.021
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.021
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.021
Eng	endoglin	0.021
Msx2	homeobox, msh-like 2	0.021
Lhx3	LIM homeobox protein 3	0.021
Wnt1	wingless-related MMTV integration site 1	0.021	Fly
Sox3	SRY-box containing gene 3	0.020
Lefty1	left right determination factor 1	0.020
C77080	expressed sequence C77080	0.020
Laptm5	lysosomal-associated protein transmembrane 5	0.020
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.020
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.019
Bmp6	bone morphogenetic protein 6	0.019
Cdh1	cadherin 1	0.019
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.019	Zebrafish
Foxd1	forkhead box D1	0.019	Mouse
Whrn	whirlin	0.018
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.018
Cav1	caveolin 1, caveolae protein	0.018
Dmrt3	doublesex and mab-3 related transcription factor 3	0.018
Alx1	ALX homeobox 1	0.018
Pld4	phospholipase D family, member 4	0.018
Hoxa11	homeobox A11	0.018
Mcl1	myeloid cell leukemia sequence 1	0.017
Cldn4	claudin 4	0.017
Meox2	mesenchyme homeobox 2	0.017
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.017
Hoxd10	homeobox D10	0.017
Efnb1	ephrin B1	0.017
Pdx1	pancreatic and duodenal homeobox 1	0.017
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.017
Irx1	Iroquois related homeobox 1 (Drosophila)	0.017
Sall3	sal-like 3 (Drosophila)	0.017
Zfhx3	zinc finger homeobox 3	0.017
Sall1	sal-like 1 (Drosophila)	0.016
Foxq1	forkhead box Q1	0.016	Mouse
Fcgr3	Fc receptor, IgG, low affinity III	0.016
Atf3	activating transcription factor 3	0.016
Pthlh	parathyroid hormone-like peptide	0.016
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.015
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.015
Ilk	integrin linked kinase	0.015
Fosl2	fos-like antigen 2	0.015
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.015
Egfl7	EGF-like domain 7	0.015
Zfp503	zinc finger protein 503	0.015
Pax9	paired box gene 9	0.015
Mrc1	mannose receptor, C type 1	0.015
Dlx2	distal-less homeobox 2	0.015
Tcf21	transcription factor 21	0.014
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.014
Fgfr3	fibroblast growth factor receptor 3	0.014	Fly
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.014
Amh	anti-Mullerian hormone	0.014
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.014
Gdf1	growth differentiation factor 1	0.014	Mouse Fly
D530037H12Rik	RIKEN cDNA D530037H12 gene	0.014
Zswim6	zinc finger, SWIM domain containing 6	0.014
Trp63	transformation related protein 63	0.014
Foxb1	forkhead box B1	0.013
Nfib	nuclear factor I/B	0.013
Ntf3	neurotrophin 3	0.013
Klf3	Kruppel-like factor 3 (basic)	0.013	Mouse
Tenc1	tensin like C1 domain-containing phosphatase	0.013
Hmx2	H6 homeobox 2	0.013
Lama1	laminin, alpha 1	0.013
Nrxn1	neurexin I	0.013
Vsx2	visual system homeobox 2	0.013
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.013
Hoxa4	homeobox A4	0.012
Gja1	gap junction protein, alpha 1	0.012
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.012
Hes5	hairy and enhancer of split 5 (Drosophila)	0.012
Pparg	peroxisome proliferator activated receptor gamma	0.012
Tgfbr2	transforming growth factor, beta receptor II	0.012
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.012
Lhx4	LIM homeobox protein 4	0.012
Gata3	GATA binding protein 3	0.012
Atoh1	atonal homolog 1 (Drosophila)	0.012
Rbms1	RNA binding motif, single stranded interacting protein 1	0.012
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.012	Fly
Clmn	calmin	0.012
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.011
Mpeg1	macrophage expressed gene 1	0.011
Tmem30b	transmembrane protein 30B	0.011
Ptpre	protein tyrosine phosphatase, receptor type, E	0.011
Prox1	prospero-related homeobox 1	0.011
Hbegf	heparin-binding EGF-like growth factor	0.011
Ccr10	chemokine (C-C motif) receptor 10	0.011
Tdgf1	teratocarcinoma-derived growth factor 1	0.011
Ppl	periplakin	0.011
Figla	folliculogenesis specific basic helix-loop-helix	0.011
Mlph	melanophilin	0.011
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.011
Cd68	CD68 antigen	0.011
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.011
Lrrk2	leucine-rich repeat kinase 2	0.011
Aoc3	amine oxidase, copper containing 3	0.011
Hoxb1	homeobox B1	0.011
Lhx5	LIM homeobox protein 5	0.011
Fgf10	fibroblast growth factor 10	0.011
Celf4	CUGBP, Elav-like family member 4	0.010
Igf1r	insulin-like growth factor I receptor	0.010
Uncx	UNC homeobox	0.010
Wnt6	wingless-related MMTV integration site 6	0.010
Lamb2	laminin, beta 2	0.010
Smad1	MAD homolog 1 (Drosophila)	0.010
Kl	klotho	0.010
Hoxb6	homeobox B6	0.010
Pitx1	paired-like homeodomain transcription factor 1	0.010
Phldb1	pleckstrin homology-like domain, family B, member 1	0.010