IMP

Process View

Mus musculus

18 genes annotated in mouse

cell aggregation

The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell aggregation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell aggregation" (in gray)

Name	Description	Probability	Func Analog Organism
Tgfb2	transforming growth factor, beta 2	0.991
Pax3	paired box gene 3	0.984
Col1a1	collagen, type I, alpha 1	0.982	Mouse
Meox2	mesenchyme homeobox 2	0.981
Fbn1	fibrillin 1	0.944
Tgfbr2	transforming growth factor, beta receptor II	0.895	Mouse
Trp53	transformation related protein 53	0.887
Pkd1	polycystic kidney disease 1 homolog	0.884
Pten	phosphatase and tensin homolog	0.821
Fgf10	fibroblast growth factor 10	0.776	Mouse
Gli2	GLI-Kruppel family member GLI2	0.702
Pax7	paired box gene 7	0.700
Mapk14	mitogen-activated protein kinase 14	0.698
Gli3	GLI-Kruppel family member GLI3	0.682
Shh	sonic hedgehog	0.662
Pitx2	paired-like homeodomain transcription factor 2	0.637
Foxc1	forkhead box C1	0.625
Lox	lysyl oxidase	0.484
Eng	endoglin	0.481
Sox9	SRY-box containing gene 9	0.458
Fgfr3	fibroblast growth factor receptor 3	0.449
Rarg	retinoic acid receptor, gamma	0.411	Mouse
Twist2	twist homolog 2 (Drosophila)	0.386
Col6a3	collagen, type VI, alpha 3	0.382
Rara	retinoic acid receptor, alpha	0.376	Mouse
Gata4	GATA binding protein 4	0.340
Prrx1	paired related homeobox 1	0.332
Bmp4	bone morphogenetic protein 4	0.327
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.310
Pax2	paired box gene 2	0.310
Fgf8	fibroblast growth factor 8	0.297
Nf1	neurofibromatosis 1	0.295
Pthlh	parathyroid hormone-like peptide	0.276
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.263
Acvr1	activin A receptor, type 1	0.252	Mouse
Rarb	retinoic acid receptor, beta	0.236	Mouse
Pax6	paired box gene 6	0.229
Rxra	retinoid X receptor alpha	0.220
Tbx1	T-box 1	0.216
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.212	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.207
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.201
Sox11	SRY-box containing gene 11	0.195	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.179
Prrx2	paired related homeobox 2	0.177
Hoxd13	homeobox D13	0.172
Col6a2	collagen, type VI, alpha 2	0.165
Hhex	hematopoietically expressed homeobox	0.143
Col11a1	collagen, type XI, alpha 1	0.143
Zeb1	zinc finger E-box binding homeobox 1	0.143
Isl1	ISL1 transcription factor, LIM/homeodomain	0.137
Atoh7	atonal homolog 7 (Drosophila)	0.129
Nodal	nodal	0.127
Twist1	twist homolog 1 (Drosophila)	0.123
Ntf3	neurotrophin 3	0.121
Col6a1	collagen, type VI, alpha 1	0.118
Fst	follistatin	0.115
Capn6	calpain 6	0.113
Gdf11	growth differentiation factor 11	0.112	Mouse
Bdnf	brain derived neurotrophic factor	0.112
Ptx3	pentraxin related gene	0.111
Egfr	epidermal growth factor receptor	0.106
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.106
Sox4	SRY-box containing gene 4	0.105	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.104
Zfpm2	zinc finger protein, multitype 2	0.101
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.095
Btbd17	BTB (POZ) domain containing 17	0.092
Tgfbr1	transforming growth factor, beta receptor I	0.090	Mouse
Col5a1	collagen, type V, alpha 1	0.089	Mouse
Tll1	tolloid-like	0.086
Foxc2	forkhead box C2	0.084
Tbx10	T-box 10	0.082
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.081
Acan	aggrecan	0.079
Sox17	SRY-box containing gene 17	0.076	Mouse
Thbs1	thrombospondin 1	0.068
Eln	elastin	0.068
Bcl6b	B-cell CLL/lymphoma 6, member B	0.067
Pou3f3	POU domain, class 3, transcription factor 3	0.067
Fstl1	follistatin-like 1	0.066
Robo3	roundabout homolog 3 (Drosophila)	0.065
Vegfa	vascular endothelial growth factor A	0.065
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.064
Tnc	tenascin C	0.064
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.060
Ednra	endothelin receptor type A	0.060
Hapln1	hyaluronan and proteoglycan link protein 1	0.059	Mouse
Creb1	cAMP responsive element binding protein 1	0.057
Kit	kit oncogene	0.057
Tbx15	T-box 15	0.055
Gal	galanin	0.055
Col8a1	collagen, type VIII, alpha 1	0.055
Thrb	thyroid hormone receptor beta	0.055	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.053
Tef	thyrotroph embryonic factor	0.052
Meox1	mesenchyme homeobox 1	0.051
Dhh	desert hedgehog	0.049
Col2a1	collagen, type II, alpha 1	0.048
Csf1	colony stimulating factor 1 (macrophage)	0.047
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.046	Mouse
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.046
Atf2	activating transcription factor 2	0.044
Eya1	eyes absent 1 homolog (Drosophila)	0.044
Mmp16	matrix metallopeptidase 16	0.041
Has2	hyaluronan synthase 2	0.041
Fkbp10	FK506 binding protein 10	0.040
Snai1	snail homolog 1 (Drosophila)	0.040
Bicc1	bicaudal C homolog 1 (Drosophila)	0.040
Mmp17	matrix metallopeptidase 17	0.040
Ebf3	early B-cell factor 3	0.040
Zic3	zinc finger protein of the cerebellum 3	0.038
Matn4	matrilin 4	0.038
Tcfap2a	transcription factor AP-2, alpha	0.037
Fzd4	frizzled homolog 4 (Drosophila)	0.037
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.036
Ret	ret proto-oncogene	0.036
Gli1	GLI-Kruppel family member GLI1	0.036
Col15a1	collagen, type XV, alpha 1	0.036
Mesp1	mesoderm posterior 1	0.035
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.033
Col19a1	collagen, type XIX, alpha 1	0.033
Nkx2-1	NK2 homeobox 1	0.033
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.033
Ghr	growth hormone receptor	0.032
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.032
Smad6	MAD homolog 6 (Drosophila)	0.032
Il6st	interleukin 6 signal transducer	0.031
Postn	periostin, osteoblast specific factor	0.031
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.031
Jun	Jun oncogene	0.031
Agtr2	angiotensin II receptor, type 2	0.030
Mrc2	mannose receptor, C type 2	0.029
Jag1	jagged 1	0.029
Mfap5	microfibrillar associated protein 5	0.029
Ltbp2	latent transforming growth factor beta binding protein 2	0.029
Sox2	SRY-box containing gene 2	0.028	Mouse
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.028
Lhx6	LIM homeobox protein 6	0.028
Hoxd11	homeobox D11	0.028
Fgf5	fibroblast growth factor 5	0.027	Mouse
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.025
Cdh5	cadherin 5	0.024
Wisp1	WNT1 inducible signaling pathway protein 1	0.024	Mouse
Foxf2	forkhead box F2	0.024
Gh	growth hormone	0.024
Dmrt1	doublesex and mab-3 related transcription factor 1	0.024
Myod1	myogenic differentiation 1	0.024	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.024
Phldb2	pleckstrin homology-like domain, family B, member 2	0.024
Acvr2b	activin receptor IIB	0.024
Igf1	insulin-like growth factor 1	0.024
Nrg1	neuregulin 1	0.023
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.023
Bgn	biglycan	0.023
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.023
Col5a2	collagen, type V, alpha 2	0.022	Mouse
Mapk11	mitogen-activated protein kinase 11	0.022	Mouse
Loxl1	lysyl oxidase-like 1	0.022
Trp63	transformation related protein 63	0.022
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.022
Dmp1	dentin matrix protein 1	0.021
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.021
Gsc	goosecoid homeobox	0.021
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.021
Foxd3	forkhead box D3	0.021
Eda	ectodysplasin-A	0.021
Ctnnb1	catenin (cadherin associated protein), beta 1	0.021
Epha3	Eph receptor A3	0.021
Fgf9	fibroblast growth factor 9	0.021	Mouse
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.020
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.020
Fbln2	fibulin 2	0.020
Wnt9b	wingless-type MMTV integration site 9B	0.020
Bmp5	bone morphogenetic protein 5	0.020
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.020
Shc1	src homology 2 domain-containing transforming protein C1	0.020
Mybph	myosin binding protein H	0.019
Fgf18	fibroblast growth factor 18	0.019
Ptf1a	pancreas specific transcription factor, 1a	0.019
Angptl2	angiopoietin-like 2	0.019
Homer1	homer homolog 1 (Drosophila)	0.019
Cdh11	cadherin 11	0.019
Aplnr	apelin receptor	0.018
Phox2a	paired-like homeobox 2a	0.018
Prox1	prospero-related homeobox 1	0.018
Lum	lumican	0.018
Met	met proto-oncogene	0.018
Onecut1	one cut domain, family member 1	0.018
Inhba	inhibin beta-A	0.018
Cdh13	cadherin 13	0.018
Matn3	matrilin 3	0.018
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.017
Socs5	suppressor of cytokine signaling 5	0.017
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.017
Gdnf	glial cell line derived neurotrophic factor	0.017
Krt75	keratin 75	0.017
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.017
Adcy4	adenylate cyclase 4	0.017
Nog	noggin	0.017
Hipk3	homeodomain interacting protein kinase 3	0.016
Jag2	jagged 2	0.016
Insm1	insulinoma-associated 1	0.016
Hoxd8	homeobox D8	0.016
Grb10	growth factor receptor bound protein 10	0.016
Nkx3-2	NK3 homeobox 2	0.016
Kcnk2	potassium channel, subfamily K, member 2	0.016
Wnt6	wingless-related MMTV integration site 6	0.016
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.016
Mapk8	mitogen-activated protein kinase 8	0.016	Mouse
Wnt7a	wingless-related MMTV integration site 7A	0.016
Ids	iduronate 2-sulfatase	0.016
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.016	Mouse
She	src homology 2 domain-containing transforming protein E	0.016
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.016
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.016
Prkg1	protein kinase, cGMP-dependent, type I	0.016
Pou3f1	POU domain, class 3, transcription factor 1	0.016
S100b	S100 protein, beta polypeptide, neural	0.016
Thbs2	thrombospondin 2	0.016
Shox2	short stature homeobox 2	0.016
Alppl2	alkaline phosphatase, placental-like 2	0.015
Prdm16	PR domain containing 16	0.015
Srpx	sushi-repeat-containing protein	0.015
Tgfb1	transforming growth factor, beta 1	0.015	Mouse
Ptgir	prostaglandin I receptor (IP)	0.015
Bmp2	bone morphogenetic protein 2	0.015
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.015
Alx4	aristaless-like homeobox 4	0.015
Tcf15	transcription factor 15	0.015
Zfp316	zinc finger protein 316	0.015
Fgf2	fibroblast growth factor 2	0.015	Mouse
Dlk1	delta-like 1 homolog (Drosophila)	0.015
Kitl	kit ligand	0.015
Alx3	aristaless-like homeobox 3	0.015
Hoxa5	homeobox A5	0.014
Hoxa3	homeobox A3	0.014
Fgf14	fibroblast growth factor 14	0.014	Mouse
Ptch2	patched homolog 2	0.014
Duox2	dual oxidase 2	0.014
Myoc	myocilin	0.014
Nkx6-1	NK6 homeobox 1	0.014
Creb3l1	cAMP responsive element binding protein 3-like 1	0.014
Dll3	delta-like 3 (Drosophila)	0.014
Mmp3	matrix metallopeptidase 3	0.014
Nes	nestin	0.014
Pax8	paired box gene 8	0.014
Pitx3	paired-like homeodomain transcription factor 3	0.014
Rbl2	retinoblastoma-like 2	0.014
Stx1b	syntaxin 1B	0.014
Eya4	eyes absent 4 homolog (Drosophila)	0.014
Gja4	gap junction protein, alpha 4	0.014
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.014
Fndc1	fibronectin type III domain containing 1	0.013
Nptx2	neuronal pentraxin 2	0.013
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.013
Col12a1	collagen, type XII, alpha 1	0.013
Klf17	Kruppel-like factor 17	0.013
Epha5	Eph receptor A5	0.013
Thbs3	thrombospondin 3	0.013
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.013
Tecta	tectorin alpha	0.013
Bcl2	B-cell leukemia/lymphoma 2	0.013
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.013
Sox10	SRY-box containing gene 10	0.013	Mouse
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.013
Apc	adenomatosis polyposis coli	0.013
Lpar1	lysophosphatidic acid receptor 1	0.013
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.013
Ptprb	protein tyrosine phosphatase, receptor type, B	0.013
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.013
Lhx1	LIM homeobox protein 1	0.013
Gpr37	G protein-coupled receptor 37	0.013
Rims4	regulating synaptic membrane exocytosis 4	0.013
Hic1	hypermethylated in cancer 1	0.013
Pitx1	paired-like homeodomain transcription factor 1	0.013
Foxd1	forkhead box D1	0.013
En2	engrailed 2	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.012
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.012
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.012
Trim47	tripartite motif-containing 47	0.012
Osr1	odd-skipped related 1 (Drosophila)	0.012
Hoxb1	homeobox B1	0.012
Arhgap4	Rho GTPase activating protein 4	0.012
Lhx5	LIM homeobox protein 5	0.012
Hoxa11	homeobox A11	0.012
Crhr1	corticotropin releasing hormone receptor 1	0.012
Mapkapk2	MAP kinase-activated protein kinase 2	0.012
Phkg1	phosphorylase kinase gamma 1	0.012
Myog	myogenin	0.012	Mouse
Col4a5	collagen, type IV, alpha 5	0.012
Cys1	cystin 1	0.012
Fbn2	fibrillin 2	0.012
C79562	expressed sequence C79562	0.011
Nrk	Nik related kinase	0.011
Xiap	X-linked inhibitor of apoptosis	0.011
Ptgis	prostaglandin I2 (prostacyclin) synthase	0.011
Hand2	heart and neural crest derivatives expressed transcript 2	0.011
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.011
Btbd3	BTB (POZ) domain containing 3	0.011
Rgs4	regulator of G-protein signaling 4	0.011
Fuz	fuzzy homolog (Drosophila)	0.011
Cdh10	cadherin 10	0.011
Tbx3	T-box 3	0.011
Pcolce	procollagen C-endopeptidase enhancer protein	0.011
Npr2	natriuretic peptide receptor 2	0.011
Fap	fibroblast activation protein	0.011
Cer1	cerberus 1 homolog (Xenopus laevis)	0.011
Dlx1	distal-less homeobox 1	0.011
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.011
Crlf1	cytokine receptor-like factor 1	0.011
Cdh6	cadherin 6	0.011
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.011
Zic1	zinc finger protein of the cerebellum 1	0.011
Hes1	hairy and enhancer of split 1 (Drosophila)	0.011
Zfp703	zinc finger protein 703	0.011
Pou3f4	POU domain, class 3, transcription factor 4	0.011
Hoxb3	homeobox B3	0.010
Hoxd1	homeobox D1	0.010
Cntn2	contactin 2	0.010
Nanog	Nanog homeobox	0.010
Tcf21	transcription factor 21	0.010
Skil	SKI-like	0.010
Vcl	vinculin	0.010
Wnt11	wingless-related MMTV integration site 11	0.010
Ebf2	early B-cell factor 2	0.010
Kdr	kinase insert domain protein receptor	0.010
Ar	androgen receptor	0.010
Ibsp	integrin binding sialoprotein	0.010