IMP

Process View

Mus musculus

14 genes annotated in mouse

cellular response to bmp stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to bmp stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to bmp stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Gata4	GATA binding protein 4	0.961	Mouse
Prrx1	paired related homeobox 1	0.931	Mouse
Col1a1	collagen, type I, alpha 1	0.920	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.915	Mouse
Msx1	homeobox, msh-like 1	0.783
Bglap	bone gamma carboxyglutamate protein	0.637
Otx2	orthodenticle homolog 2 (Drosophila)	0.618
Pax3	paired box gene 3	0.552
Col1a2	collagen, type I, alpha 2	0.441	Mouse
Tgfb2	transforming growth factor, beta 2	0.424
Col5a1	collagen, type V, alpha 1	0.361	Mouse
Smad1	MAD homolog 1 (Drosophila)	0.357
Sox9	SRY-box containing gene 9	0.356
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.354
Sfrp2	secreted frizzled-related protein 2	0.338
Prrx2	paired related homeobox 2	0.330	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.300
Isl1	ISL1 transcription factor, LIM/homeodomain	0.249
Ntf3	neurotrophin 3	0.238
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.231
Neurod1	neurogenic differentiation 1	0.223	Mouse
Axin1	axin 1	0.213
Hand1	heart and neural crest derivatives expressed transcript 1	0.196	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.191	Mouse
Shh	sonic hedgehog	0.189
Col3a1	collagen, type III, alpha 1	0.187	Mouse
Acvr1	activin A receptor, type 1	0.181
Gata1	GATA binding protein 1	0.181	Mouse
Snai1	snail homolog 1 (Drosophila)	0.180
Mecom	MDS1 and EVI1 complex locus	0.150
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.147
Runx2	runt related transcription factor 2	0.145
Bglap2	bone gamma-carboxyglutamate protein 2	0.144	Mouse
Col6a2	collagen, type VI, alpha 2	0.140
Nhlh1	nescient helix loop helix 1	0.133	Mouse
Fbn1	fibrillin 1	0.111
Smad3	MAD homolog 3 (Drosophila)	0.106	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.105
Ptf1a	pancreas specific transcription factor, 1a	0.104	Mouse
Dlx2	distal-less homeobox 2	0.098	Mouse
Col5a2	collagen, type V, alpha 2	0.097	Mouse
Fgf8	fibroblast growth factor 8	0.089
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.087
Tgfbr2	transforming growth factor, beta receptor II	0.087
Eln	elastin	0.085
Col6a1	collagen, type VI, alpha 1	0.078
Twist2	twist homolog 2 (Drosophila)	0.078	Mouse
Foxc2	forkhead box C2	0.075
Bmp7	bone morphogenetic protein 7	0.074
Gli3	GLI-Kruppel family member GLI3	0.067
Gbx2	gastrulation brain homeobox 2	0.066
Gli2	GLI-Kruppel family member GLI2	0.064
Dlx5	distal-less homeobox 5	0.064
Col22a1	collagen, type XXII, alpha 1	0.058
Tal1	T-cell acute lymphocytic leukemia 1	0.058	Mouse
Col11a1	collagen, type XI, alpha 1	0.057	Mouse
Obsl1	obscurin-like 1	0.056
Ctsk	cathepsin K	0.055
Bgn	biglycan	0.055
Csf1	colony stimulating factor 1 (macrophage)	0.055
Hoxb1	homeobox B1	0.055
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.054
Eng	endoglin	0.052
Onecut1	one cut domain, family member 1	0.051
Twist1	twist homolog 1 (Drosophila)	0.051	Mouse
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.049
Dlx1	distal-less homeobox 1	0.048
Neurog2	neurogenin 2	0.048	Mouse
Erbb2ip	Erbb2 interacting protein	0.047
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.046
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.045
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.044	Mouse
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.043
Ebf3	early B-cell factor 3	0.042
Fgfr2	fibroblast growth factor receptor 2	0.042
Lep	leptin	0.041
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.041
Fstl1	follistatin-like 1	0.040
Efna2	ephrin A2	0.040
Col6a3	collagen, type VI, alpha 3	0.039
Lox	lysyl oxidase	0.039
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.038	Mouse
Smad2	MAD homolog 2 (Drosophila)	0.038	Mouse
Gsc	goosecoid homeobox	0.036
Gnrhr	gonadotropin releasing hormone receptor	0.036
Fshr	follicle stimulating hormone receptor	0.036
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.036
Msx2	homeobox, msh-like 2	0.035
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.035
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.035
Col13a1	collagen, type XIII, alpha 1	0.034
Loxl1	lysyl oxidase-like 1	0.032
Hes5	hairy and enhancer of split 5 (Drosophila)	0.032
Fgfr3	fibroblast growth factor receptor 3	0.031
Neurog3	neurogenin 3	0.031	Mouse
Amh	anti-Mullerian hormone	0.030
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.030
Hic1	hypermethylated in cancer 1	0.030
Apc	adenomatosis polyposis coli	0.030
Eya1	eyes absent 1 homolog (Drosophila)	0.030
Pdx1	pancreatic and duodenal homeobox 1	0.029
Mmp2	matrix metallopeptidase 2	0.029
Cd248	CD248 antigen, endosialin	0.029
Chrd	chordin	0.028
Tcfap2a	transcription factor AP-2, alpha	0.027
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.027
Ghr	growth hormone receptor	0.027
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.027
Inhba	inhibin beta-A	0.027
Hoxa1	homeobox A1	0.027
Srrm4	serine/arginine repetitive matrix 4	0.025
Hoxd3	homeobox D3	0.025
Capn6	calpain 6	0.025
Col15a1	collagen, type XV, alpha 1	0.025
Neurod4	neurogenic differentiation 4	0.025	Mouse
Hhex	hematopoietically expressed homeobox	0.024
Thbs1	thrombospondin 1	0.023
Lhx3	LIM homeobox protein 3	0.023
Ptch1	patched homolog 1	0.022
Pcolce	procollagen C-endopeptidase enhancer protein	0.022
Emid2	EMI domain containing 2	0.022
Hoxa13	homeobox A13	0.022
Mn1	meningioma 1	0.022
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.021
Pou4f3	POU domain, class 4, transcription factor 3	0.021
Sparc	secreted acidic cysteine rich glycoprotein	0.021
Gja1	gap junction protein, alpha 1	0.021
Myog	myogenin	0.021
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.020
Foxc1	forkhead box C1	0.020
Cbfb	core binding factor beta	0.020
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.020
Pou4f2	POU domain, class 4, transcription factor 2	0.020
Pitx3	paired-like homeodomain transcription factor 3	0.020
Nrk	Nik related kinase	0.020
Mgp	matrix Gla protein	0.020	Mouse
Foxf1a	forkhead box F1a	0.020
Foxd3	forkhead box D3	0.020
Hmx3	H6 homeobox 3	0.019
Smad6	MAD homolog 6 (Drosophila)	0.019	Mouse
Ccdc80	coiled-coil domain containing 80	0.019
Acan	aggrecan	0.019
Cpz	carboxypeptidase Z	0.019
Fzd2	frizzled homolog 2 (Drosophila)	0.019
Gata6	GATA binding protein 6	0.019
Wnt6	wingless-related MMTV integration site 6	0.019
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.019
Pax9	paired box gene 9	0.019
Krt14	keratin 14	0.019
Pthlh	parathyroid hormone-like peptide	0.019
Wnt11	wingless-related MMTV integration site 11	0.019
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.018
Gas1	growth arrest specific 1	0.018
Arsi	arylsulfatase i	0.018
Ebf2	early B-cell factor 2	0.018
Zfpm2	zinc finger protein, multitype 2	0.018
Dlk1	delta-like 1 homolog (Drosophila)	0.018
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.017
Pitx1	paired-like homeodomain transcription factor 1	0.017
Efs	embryonal Fyn-associated substrate	0.017
Tbx20	T-box 20	0.017
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.016
Gpc3	glypican 3	0.016
Lhx9	LIM homeobox protein 9	0.016
Fli1	Friend leukemia integration 1	0.016
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.016
Shox2	short stature homeobox 2	0.016
Col16a1	collagen, type XVI, alpha 1	0.016
Foxg1	forkhead box G1	0.015
Irx4	Iroquois related homeobox 4 (Drosophila)	0.015
Fgf10	fibroblast growth factor 10	0.015
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.015
Col8a1	collagen, type VIII, alpha 1	0.015
Tbx1	T-box 1	0.015
Ptk2	PTK2 protein tyrosine kinase 2	0.015
Tnni1	troponin I, skeletal, slow 1	0.015
Srpx	sushi-repeat-containing protein	0.015
Thbs2	thrombospondin 2	0.015
Gfi1b	growth factor independent 1B	0.015
Bnc1	basonuclin 1	0.015
Mab21l2	mab-21-like 2 (C. elegans)	0.015
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.015
Pax6	paired box gene 6	0.015
Col2a1	collagen, type II, alpha 1	0.014
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.014
Tgfb1	transforming growth factor, beta 1	0.014
Wisp1	WNT1 inducible signaling pathway protein 1	0.014
Mfap4	microfibrillar-associated protein 4	0.014
Tbx3	T-box 3	0.014
Tbx5	T-box 5	0.014
Col9a1	collagen, type IX, alpha 1	0.014
Zic1	zinc finger protein of the cerebellum 1	0.014
Bmp2	bone morphogenetic protein 2	0.014	Human Rat
Lum	lumican	0.014
Gsx2	GS homeobox 2	0.013
Loxl3	lysyl oxidase-like 3	0.013
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.013
Smo	smoothened homolog (Drosophila)	0.013
Ermap	erythroblast membrane-associated protein	0.013
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.013
Smad7	MAD homolog 7 (Drosophila)	0.013	Mouse
Sh3pxd2a	SH3 and PX domains 2A	0.013
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.013
Tagln	transgelin	0.013
Epor	erythropoietin receptor	0.013
Col4a1	collagen, type IV, alpha 1	0.012
Gpr50	G-protein-coupled receptor 50	0.012
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.012
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.012
Esr1	estrogen receptor 1 (alpha)	0.012
Mrc2	mannose receptor, C type 2	0.012
Nkx3-2	NK3 homeobox 2	0.012
Dll1	delta-like 1 (Drosophila)	0.012
Fkbp10	FK506 binding protein 10	0.012
Sp7	Sp7 transcription factor 7	0.012
Tmprss3	transmembrane protease, serine 3	0.012
Mfap2	microfibrillar-associated protein 2	0.012
Wnt5a	wingless-related MMTV integration site 5A	0.012
Epha3	Eph receptor A3	0.012
Crb2	crumbs homolog 2 (Drosophila)	0.012
Atoh8	atonal homolog 8 (Drosophila)	0.012
Gata2	GATA binding protein 2	0.012	Mouse
Scara3	scavenger receptor class A, member 3	0.012
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.012
Mybpc3	myosin binding protein C, cardiac	0.011
Matn1	matrilin 1, cartilage matrix protein	0.011
Rnf111	ring finger 111	0.011
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.011
Tcfap2b	transcription factor AP-2 beta	0.011
Ednra	endothelin receptor type A	0.011
Hoxd13	homeobox D13	0.011
Dlx6	distal-less homeobox 6	0.011
Sox7	SRY-box containing gene 7	0.011
Amhr2	anti-Mullerian hormone type 2 receptor	0.011
Has2	hyaluronan synthase 2	0.011
Leprel2	leprecan-like 2	0.011
Csf1r	colony stimulating factor 1 receptor	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
Kiss1r	KISS1 receptor	0.011
Robo3	roundabout homolog 3 (Drosophila)	0.011
Espn	espin	0.011
S1pr2	sphingosine-1-phosphate receptor 2	0.011
Nrg1	neuregulin 1	0.010
Gnrh1	gonadotropin releasing hormone 1	0.010
Ush1g	Usher syndrome 1G homolog (human)	0.010
Yap1	yes-associated protein 1	0.010
Timp1	tissue inhibitor of metalloproteinase 1	0.010
Dbh	dopamine beta hydroxylase	0.010
Lmx1a	LIM homeobox transcription factor 1 alpha	0.010