IMP

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Mus musculus

25 genes annotated in mouse

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negative regulation of protein complex assembly

GO:0031333

Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein complex assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein complex assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.323
Jag1	jagged 1	0.319
Pitx1	paired-like homeodomain transcription factor 1	0.255
Pitx2	paired-like homeodomain transcription factor 2	0.241
Notch2	Notch gene homolog 2 (Drosophila)	0.202
Rac1	RAS-related C3 botulinum substrate 1	0.178
Wdr1	WD repeat domain 1	0.176	Yeast Worm
Notch1	Notch gene homolog 1 (Drosophila)	0.173
Ctnnb1	catenin (cadherin associated protein), beta 1	0.139
Trim30d	tripartite motif-containing 30D	0.138	Mouse
Efnb2	ephrin B2	0.104
Pten	phosphatase and tensin homolog	0.090
Ncstn	nicastrin	0.089
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.083
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.079
Ldb3	LIM domain binding 3	0.074
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.074
Trim30a	tripartite motif-containing 30A	0.069
Lrp6	low density lipoprotein receptor-related protein 6	0.066
Scn5a	sodium channel, voltage-gated, type V, alpha	0.062
Hif1a	hypoxia inducible factor 1, alpha subunit	0.062
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.055
Hccs	holocytochrome c synthetase	0.053
Ptp4a2	protein tyrosine phosphatase 4a2	0.050
Lrrk2	leucine-rich repeat kinase 2	0.049
Psen1	presenilin 1	0.048	Mouse
Tal1	T-cell acute lymphocytic leukemia 1	0.048
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.048
Arpc4	actin related protein 2/3 complex, subunit 4	0.047
Stat1	signal transducer and activator of transcription 1	0.045
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.042
Foxh1	forkhead box H1	0.042
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.042
Arf1	ADP-ribosylation factor 1	0.042
Axin1	axin 1	0.039
Emx1	empty spiracles homolog 1 (Drosophila)	0.039
Vhl	von Hippel-Lindau tumor suppressor	0.037
Pcdhgb1	protocadherin gamma subfamily B, 1	0.035
Robo1	roundabout homolog 1 (Drosophila)	0.035
Zic3	zinc finger protein of the cerebellum 3	0.034
Slit3	slit homolog 3 (Drosophila)	0.030
Actb	actin, beta	0.030
Foxc1	forkhead box C1	0.029
Nodal	nodal	0.028
Dnm1	dynamin 1	0.027
Pax2	paired box gene 2	0.026
Wt1	Wilms tumor 1 homolog	0.025
Kif5b	kinesin family member 5B	0.024
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.024	Mouse
Lhx1	LIM homeobox protein 1	0.024
Ptk2	PTK2 protein tyrosine kinase 2	0.024
Prkce	protein kinase C, epsilon	0.023
Rap1b	RAS related protein 1b	0.023
Chuk	conserved helix-loop-helix ubiquitous kinase	0.023
Msn	moesin	0.023
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.023
Rxra	retinoid X receptor alpha	0.022
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.022
Foxc2	forkhead box C2	0.022
Arhgap1	Rho GTPase activating protein 1	0.022
Bdnf	brain derived neurotrophic factor	0.022
Vangl2	vang-like 2 (van gogh, Drosophila)	0.021
Gata4	GATA binding protein 4	0.021
Vegfa	vascular endothelial growth factor A	0.021
Vasp	vasodilator-stimulated phosphoprotein	0.021
Lef1	lymphoid enhancer binding factor 1	0.021
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.021	Human
Robo2	roundabout homolog 2 (Drosophila)	0.021
Noto	notochord homolog (Xenopus laevis)	0.019
Abi1	abl-interactor 1	0.019
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.019
Ikbkg	inhibitor of kappaB kinase gamma	0.019
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.019
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.019
Hoxa1	homeobox A1	0.018
Bmp5	bone morphogenetic protein 5	0.018
Efna1	ephrin A1	0.018
Gja1	gap junction protein, alpha 1	0.018
Crb2	crumbs homolog 2 (Drosophila)	0.018
Cfc1	cripto, FRL-1, cryptic family 1	0.018
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.017
Capzb	capping protein (actin filament) muscle Z-line, beta	0.017
Dnahc11	dynein, axonemal, heavy chain 11	0.017
Siah2	seven in absentia 2	0.017
Apc	adenomatosis polyposis coli	0.016
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.016
Ifi203	interferon activated gene 203	0.016
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.016
Diablo	diablo homolog (Drosophila)	0.016
Trim12a	tripartite motif-containing 12A	0.016	Mouse
Tbx4	T-box 4	0.016	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.016
Ntf3	neurotrophin 3	0.016
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.016
Cd274	CD274 antigen	0.015
Nphs2	nephrosis 2 homolog, podocin (human)	0.015
Tbx3	T-box 3	0.015	Mouse
Dll4	delta-like 4 (Drosophila)	0.015
Thrb	thyroid hormone receptor beta	0.015
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.015
Gnb1	guanine nucleotide binding protein (G protein), beta 1	0.014
Parp14	poly (ADP-ribose) polymerase family, member 14	0.014
Ikbkb	inhibitor of kappaB kinase beta	0.014
Pitpna	phosphatidylinositol transfer protein, alpha	0.014
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.014
Tubb5	tubulin, beta 5	0.014
Zfpm2	zinc finger protein, multitype 2	0.014
Rhoa	ras homolog gene family, member A	0.014
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.013
Gbx2	gastrulation brain homeobox 2	0.013
Hes7	hairy and enhancer of split 7 (Drosophila)	0.013
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.013
Fam49b	family with sequence similarity 49, member B	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.013	Human
Adam17	a disintegrin and metallopeptidase domain 17	0.013
Cd151	CD151 antigen	0.013
Cab39	calcium binding protein 39	0.013
Hand2	heart and neural crest derivatives expressed transcript 2	0.013
Foxg1	forkhead box G1	0.013
Oas1b	2'-5' oligoadenylate synthetase 1B	0.013
Nos3	nitric oxide synthase 3, endothelial cell	0.013
Arrb2	arrestin, beta 2	0.013
Ctnnd1	catenin (cadherin associated protein), delta 1	0.013
Samd9l	sterile alpha motif domain containing 9-like	0.013
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.012
Traf2	TNF receptor-associated factor 2	0.012
Gata2	GATA binding protein 2	0.012
Erlin2	ER lipid raft associated 2	0.012
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.012
Duox2	dual oxidase 2	0.012
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.012
Arrb1	arrestin, beta 1	0.012
Cd28	CD28 antigen	0.012
Kif3a	kinesin family member 3A	0.012
Irf9	interferon regulatory factor 9	0.012
Gata1	GATA binding protein 1	0.012
Cfl1	cofilin 1, non-muscle	0.012
Dll1	delta-like 1 (Drosophila)	0.012
Braf	Braf transforming gene	0.012
Fgfr2	fibroblast growth factor receptor 2	0.012
Myo7a	myosin VIIA	0.012
Gbp7	guanylate binding protein 7	0.012
Psen2	presenilin 2	0.012
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.012
Stx7	syntaxin 7	0.012
Gm12185	predicted gene 12185	0.012
Psap	prosaposin	0.012
Ilk	integrin linked kinase	0.012
Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2	0.012
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.011
Mndal	myeloid nuclear differentiation antigen like	0.011
Nkx3-2	NK3 homeobox 2	0.011
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.011
Nsf	N-ethylmaleimide sensitive fusion protein	0.011
Dnahc5	dynein, axonemal, heavy chain 5	0.011
Gata3	GATA binding protein 3	0.011
Slc25a24	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24	0.011
Cbfb	core binding factor beta	0.011
Shh	sonic hedgehog	0.011
Mtpn	myotrophin	0.011	Human
Ssbp2	single-stranded DNA binding protein 2	0.011
Rnd3	Rho family GTPase 3	0.011
Casp8	caspase 8	0.011
Calm1	calmodulin 1	0.011
Epha3	Eph receptor A3	0.011
Sept7	septin 7	0.011
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.010
Bcl2	B-cell leukemia/lymphoma 2	0.010
L1cam	L1 cell adhesion molecule	0.010
Csde1	cold shock domain containing E1, RNA binding	0.010
Ifi44	interferon-induced protein 44	0.010
Tlx3	T-cell leukemia, homeobox 3	0.010
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.010
Arpc5	actin related protein 2/3 complex, subunit 5	0.010
Rab11a	RAB11a, member RAS oncogene family	0.010
Htt	huntingtin	0.010
Snca	synuclein, alpha	0.010	Human
D630037F22Rik	RIKEN cDNA D630037F22 gene	0.010
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.010
Coro1c	coronin, actin binding protein 1C	0.010
Slit1	slit homolog 1 (Drosophila)	0.010