IMP

Process View

Mus musculus

11 genes annotated in mouse

Multi-species View

positive regulation of humoral immune response

GO:0002922

Any process that activates or increases the frequency, rate, or extent of a humoral immune response.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of humoral immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of humoral immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.964
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.954	Fly
Lyz2	lysozyme 2	0.932
Ikbkb	inhibitor of kappaB kinase beta	0.728	Fly
Igh	immunoglobulin heavy chain complex	0.687
Ccr1	chemokine (C-C motif) receptor 1	0.588	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.497
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.444
Ikbkg	inhibitor of kappaB kinase gamma	0.409
Cd19	CD19 antigen	0.408
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.378
Btk	Bruton agammaglobulinemia tyrosine kinase	0.353
Ikzf1	IKAROS family zinc finger 1	0.328
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.319
Ptprc	protein tyrosine phosphatase, receptor type, C	0.285
Il4	interleukin 4	0.219
Cd40	CD40 antigen	0.215
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.210
Lta	lymphotoxin A	0.195
Cd44	CD44 antigen	0.179
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.159
Cxcl13	chemokine (C-X-C motif) ligand 13	0.145
Ccr2	chemokine (C-C motif) receptor 2	0.140	Mouse
Tlr4	toll-like receptor 4	0.140
H2-Eb1	histocompatibility 2, class II antigen E beta	0.117
Il2	interleukin 2	0.109
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.106
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.105
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.105
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.102
Pou2af1	POU domain, class 2, associating factor 1	0.094
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.081
Ifng	interferon gamma	0.081
Il1b	interleukin 1 beta	0.077
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.076
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.075
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.070	Fly
Cxcr5	chemokine (C-X-C motif) receptor 5	0.069	Mouse
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.065
Fyn	Fyn proto-oncogene	0.059
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.059
Ccr6	chemokine (C-C motif) receptor 6	0.059	Mouse
Casp1	caspase 1	0.056	Fly
Tlr2	toll-like receptor 2	0.053
Ccl2	chemokine (C-C motif) ligand 2	0.052
Inpp5d	inositol polyphosphate-5-phosphatase D	0.052
Icos	inducible T-cell co-stimulator	0.052
Fas	Fas (TNF receptor superfamily member 6)	0.052
Cyld	cylindromatosis (turban tumor syndrome)	0.052
Xcr1	chemokine (C motif) receptor 1	0.048	Mouse
Cd180	CD180 antigen	0.047
Il2rg	interleukin 2 receptor, gamma chain	0.044
Ifngr1	interferon gamma receptor 1	0.042
Cd28	CD28 antigen	0.041
Sfpi1	SFFV proviral integration 1	0.040
Prdm1	PR domain containing 1, with ZNF domain	0.039
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.036
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.035
Il27ra	interleukin 27 receptor, alpha	0.031
Mefv	Mediterranean fever	0.030
Cd22	CD22 antigen	0.030
Cd4	CD4 antigen	0.028
Saa4	serum amyloid A 4	0.025
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.025
Il22	interleukin 22	0.025
Cxcr2	chemokine (C-X-C motif) receptor 2	0.024	Mouse
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.024
Ciita	class II transactivator	0.024
Fcrla	Fc receptor-like A	0.022
Ltb	lymphotoxin B	0.022
Il7	interleukin 7	0.022
Ccl4	chemokine (C-C motif) ligand 4	0.021
Msx3	homeobox, msh-like 3	0.021
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.020
Apcs	serum amyloid P-component	0.020
Pycard	PYD and CARD domain containing	0.020
H2-Ob	histocompatibility 2, O region beta locus	0.019
Ncr1	natural cytotoxicity triggering receptor 1	0.019
Flt3	FMS-like tyrosine kinase 3	0.019
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.019
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.019
Itgax	integrin alpha X	0.019
Il1r1	interleukin 1 receptor, type I	0.019
Tcra	T-cell receptor alpha chain	0.018
Selp	selectin, platelet	0.018
Vpreb3	pre-B lymphocyte gene 3	0.018
Il6	interleukin 6	0.018
Sh2d2a	SH2 domain protein 2A	0.018
Itk	IL2-inducible T-cell kinase	0.017
C3ar1	complement component 3a receptor 1	0.017
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.017
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.017
Cybb	cytochrome b-245, beta polypeptide	0.016
H2-DMa	histocompatibility 2, class II, locus DMa	0.016
Foxd4	forkhead box D4	0.016
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.015
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.015	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015	Fly
Il1rn	interleukin 1 receptor antagonist	0.015
Trp73	transformation related protein 73	0.015
Casp8	caspase 8	0.015
Blk	B lymphoid kinase	0.015
Il15ra	interleukin 15 receptor, alpha chain	0.015
Ccr5	chemokine (C-C motif) receptor 5	0.015	Mouse
Socs1	suppressor of cytokine signaling 1	0.015
Il18r1	interleukin 18 receptor 1	0.015
Tlr8	toll-like receptor 8	0.014
Ccr3	chemokine (C-C motif) receptor 3	0.014	Mouse
Il1f9	interleukin 1 family, member 9	0.014
Itgal	integrin alpha L	0.014
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.014	Mouse
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.014
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.013	Fly
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.013
Card11	caspase recruitment domain family, member 11	0.013
Irf4	interferon regulatory factor 4	0.013
Birc3	baculoviral IAP repeat-containing 3	0.013
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.013
Mmp9	matrix metallopeptidase 9	0.013
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.013
F9	coagulation factor IX	0.013
Marco	macrophage receptor with collagenous structure	0.013
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.013
Il10	interleukin 10	0.012
Rel	reticuloendotheliosis oncogene	0.012
Foxp3	forkhead box P3	0.011
Ubd	ubiquitin D	0.011
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.011
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.011
Irf1	interferon regulatory factor 1	0.011
Hrh1	histamine receptor H1	0.011
H2-M9	histocompatibility 2, M region locus 9	0.011
Cd7	CD7 antigen	0.011
Pax5	paired box gene 5	0.011
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.011
Itgb2	integrin beta 2	0.011
AF251705	cDNA sequence AF251705	0.011
Fasl	Fas ligand (TNF superfamily, member 6)	0.011	Mouse
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.011
Dmbt1	deleted in malignant brain tumors 1	0.010
Fpr1	formyl peptide receptor 1	0.010
Lair1	leukocyte-associated Ig-like receptor 1	0.010
Prg3	proteoglycan 3	0.010