IMP

Process View

Danio rerio

3 genes annotated in zebrafish

regulation of wnt signaling pathway calcium modulating pathway

Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of wnt signaling pathway calcium modulating pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of wnt signaling pathway calcium modulating pathway" (in gray)

Name	Description	Probability	Func Analog Organism
wnt1	wingless-type MMTV integration site family, member 1	0.999	Zebrafish
wnt8b	wingless-type MMTV integration site family, member 8b	0.998	Zebrafish
tbx1	T-box 1	0.988
wnt3a	wingless-type MMTV integration site family, member 3A	0.979	Zebrafish
wnt4a	wingless-type MMTV integration site family, member 4a	0.977	Zebrafish
wnt10a	wingless-type MMTV integration site family, member 10a	0.954	Zebrafish
hnf1ba	HNF1 homeobox Ba	0.916
wnt10b	wingless-type MMTV integration site family, member 10b	0.848	Zebrafish
wnt9b	wingless-type MMTV integration site family, member 9B	0.828	Zebrafish
wnt3	wingless-type MMTV integration site family, member 3	0.803	Zebrafish
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.769	Zebrafish
wnt2	wingless-type MMTV integration site family member 2	0.722	Zebrafish
wnt9a	wingless-type MMTV integration site family, member 9A	0.721	Zebrafish
zfyve26	zinc finger, FYVE domain containing 26	0.643
bmp2a	bone morphogenetic protein 2a	0.633
wnt11	wingless-type MMTV integration site family, member 11	0.586	Zebrafish
lef1	lymphocyte enhancer binding factor 1	0.538
gli1	GLI-Kruppel family member 1	0.537
wnt11r	wingless-type MMTV integration site family, member 11, related	0.508	Zebrafish
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.492	Zebrafish
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.474
wnt16	wingless-type MMTV integration site family, member 16	0.404
fgf17	fibroblast growth factor 17	0.391
hoxd4a	homeo box D4a	0.389
sfrp1a	secreted frizzled-related protein 1a	0.357
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.339	Zebrafish
dkk1b	dickkopf 1b	0.335
twist3	twist3	0.332
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.325
col11a2	collagen type XI alpha-2	0.304
wnt5a	wingless-type MMTV integration site family, member 5a	0.293	Zebrafish
fgf3	fibroblast growth factor 3	0.287
map2k7	mitogen-activated protein kinase kinase 7	0.277
map2k4a	mitogen-activated protein kinase kinase 4a	0.266
fgf4	fibroblast growth factor 4	0.265
dharma	dharma	0.257
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.255
zbtb4	zinc finger and BTB domain containing 4	0.229
flh	floating head	0.221
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.187
si:dkey-273o13.1	si:dkey-273o13.1	0.178
mapk14a	mitogen-activated protein kinase 14a	0.177
scube2	signal peptide, CUB domain, EGF-like 2	0.170
her5	hairy-related 5	0.168
znf711	zinc finger protein 711	0.160
eng2a	engrailed 2a	0.147
map2k4b	mitogen-activated protein kinase kinase 4b	0.146
wls	wntless homolog (Drosophila)	0.143
pou5f1	POU domain, class 5, transcription factor 1	0.142
fgf8a	fibroblast growth factor 8 a	0.136
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.136
ntn1b	netrin 1b	0.134
spry2	sprouty homolog 2	0.127
rest	RE1-silencing transcription factor	0.125
gli2b	GLI-Kruppel family member GLI2b	0.124
eya1	eyes absent homolog 1	0.121
tfpi2	tissue factor pathway inhibitor 2	0.121
lhx2b	LIM homeobox 2b	0.120
epb4.1l4	erythrocyte protein band 4.1-like 4	0.119
gbx2	gastrulation brain homeo box 2	0.118
oprm1	opioid receptor, mu 1	0.116
sfrp1b	secreted frizzled-related protein 1b	0.115
ihha	Indian hedgehog homolog a	0.115
ptch1	patched 1	0.113
pdlim7	PDZ and LIM domain 7	0.109
sb:cb81	sb:cb81	0.109
zgc:171802	zgc:171802	0.108
vent	ventral expressed homeobox	0.098
glra1	glycine receptor, alpha 1	0.097
dab1b	disabled homolog 1b (Drosophila)	0.097
fbn2b	fibrillin 2b	0.096
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.096
wnt5b	wingless-type MMTV integration site family, member 5b	0.095
tnnt2a	troponin T2a, cardiac	0.094
pdlim3b	PDZ and LIM domain 3b	0.093
ankrd6	ankyrin repeat domain 6	0.093
bmp7a	bone morphogenetic protein 7a	0.092
kop	askopos	0.091
oep	one-eyed pinhead	0.091
snai1b	snail homolog 1b (Drosophila)	0.088
admp	anti-dorsalizing morphogenic protein	0.086
ndr2	nodal-related 2	0.084
ism1	isthmin 1	0.084
runx2b	runt-related transcription factor 2b	0.082
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.082
sult1st4	sulfotransferase family 1, cytosolic sulfotransferase 4	0.082
pglyrp2	peptidoglycan recognition protein 2	0.080
dusp6	dual specificity phosphatase 6	0.077
ndr1	nodal-related 1	0.072
dld	deltaD	0.069
stat1b	signal transducer and activator of transcription 1b	0.068
hmx4	H6 family homeobox 4	0.068
lrmp	lymphoid-restricted membrane protein	0.067
sox2	SRY-box containing gene 2	0.065
gpc4	glypican 4	0.065
msxb	muscle segment homeobox B	0.064
wnt4b	wingless-type MMTV integration site family, member 4b	0.062	Zebrafish
chrna4	cholinergic receptor, nicotinic, alpha 4	0.062
robo1	roundabout homolog 1	0.062
disc1	disrupted in schizophrenia 1	0.062
LOC566708	FL cytokine receptor-like	0.060
cx27.5	connexin 27.5	0.055
fbln1	fibulin 1	0.055
notum3	notum 3	0.055
mapk6	mitogen-activated protein kinase 6	0.054
brd4	bromodomain containing 4	0.054
tll1	tolloid-like 1	0.053
dab1a	disabled homolog 1a (Drosophila)	0.052
csnk1da	casein kinase 1, delta a	0.051
lft2	lefty2	0.050
pth2	parathyroid hormone 2	0.049
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.049
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.048
bmp4	bone morphogenetic protein 4	0.048
limk1	LIM domain kinase 1	0.047
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.046
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.045	Zebrafish
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.044
cdx4	caudal type homeo box transcription factor 4	0.044
igf1ra	insulin-like growth factor 1a receptor	0.044
tbx16	T-box gene 16	0.044
twist1a	twist1a	0.043
her3	hairy-related 3	0.042
wif1	wnt inhibitory factor 1	0.042
dbx1a	developing brain homeobox 1a	0.041
hoxa13b	homeo box A13b	0.040
ptch2	patched 2	0.040
buc	bucky ball	0.040
oprk1	opioid receptor, kappa 1	0.039
sox3	SRY-box containing gene 3	0.039
oxtl	oxytocin-like	0.037
hapln1a	hyaluronan and proteoglycan link protein 1a	0.036
im:7162646	im:7162646	0.036
rnd1l	Rho family GTPase 1 like	0.036
slco1f1	solute carrier organic anion transporter family, member 1F1	0.035
fzd10	frizzled homolog 10	0.035
sass6	spindle assembly 6 homolog (C. elegans)	0.034
sulf1	sulfatase 1	0.034
sult3st1	sulfotransferase family 3, cytosolic sulfotransferase 1	0.034
mapk8b	mitogen-activated protein kinase 8b	0.033
mxtx2	mix-type homeobox gene 2	0.033
hspb1	heat shock protein, alpha-crystallin-related, 1	0.032
hmx1	H6 homeo box 1	0.031
boc	brother of CDO	0.031
bactin2	bactin2	0.031
sox17	SRY-box containing gene 17	0.031
runx1	runt-related transcription factor 1	0.030
or115-15	odorant receptor, family F, subfamily 115, member 15	0.029
sp5l	Sp5 transcription factor-like	0.029
pdlim2	PDZ and LIM domain 2 (mystique)	0.029
barx1	BarH-like homeobox 1	0.028
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.028
bmp1a	bone morphogenetic protein 1a	0.028
si:ch1073-351m12.1	si:ch1073-351m12.1	0.028
zgc:193613	zgc:193613	0.026
dag1	dystroglycan 1	0.026
gle1	GLE1 RNA export mediator homolog (yeast)	0.026
nkd1	naked cuticle homolog 1 (Drosophila)	0.026
LOC100359374	BCL-WAV	0.026
gc2	guanylyl cyclase 2	0.026
limk2	LIM domain kinase 2	0.025
fgf6a	fibroblast growth factor 6a	0.025
zgc:162270	zgc:162270	0.025
comta	catechol-O-methyltransferase a	0.025
frzb	frizzled-related protein	0.024
pdlim3a	PDZ and LIM domain 3a	0.024
tcf21	transcription factor 21	0.024
trim3a	tripartite motif-containing 3a	0.024
glceb	glucuronyl C5-epimerase b	0.024
etv2	ets variant gene 2	0.023
cables1	Cdk5 and Abl enzyme substrate 1	0.023
spaw	southpaw	0.022
npy8ar	neuropeptide Y receptor Y8a	0.022
mib	mind bomb	0.022
chrnb3b	cholinergic receptor, nicotinic, beta polypeptide 3b	0.022
pggt1b	protein geranylgeranyltransferase type I, beta subunit	0.022
glcea	glucuronyl C5-epimerase a	0.022
si:dkey-236e20.2	si:dkey-236e20.2	0.022
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.021
prkar1aa	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a	0.021
spry1	sprouty homolog 1 (Drosophila)	0.021
ppp1r3ca	protein phosphatase 1, regulatory (inhibitor) subunit 3Ca	0.021
notch3	notch homolog 3	0.021
lrrc50	leucine rich repeat containing 50	0.021
sox32	SRY-box containing gene 32	0.021
ved	ventrally expressed dharma/bozozok antagonist	0.021
axin1	axin 1	0.020
tbx24	T-box 24	0.020
rargb	retinoic acid receptor, gamma b	0.020
ca15b	carbonic anhydrase XV b	0.020
fbxl14b	F-box and leucine-rich repeat protein 14b	0.020
ephb4b	eph receptor B4b	0.019
sfrp5	secreted frizzled-related protein 5	0.019
odz4	odd Oz/ten-m homolog 4	0.019
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.019
pomca	proopiomelanocortin a	0.018
ntla	no tail a	0.018
si:ch211-173o4.2	si:ch211-173o4.2	0.018
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.018
mc3r	melanocortin 3 receptor	0.018
cpa2	carboxypeptidase A2 (pancreatic)	0.017
wu:fj62d01	wu:fj62d01	0.017
lhx1b	LIM homeobox 1b	0.017
hoxa2b	homeo box A2b	0.017
foxd3	forkhead box D3	0.017
csnk1db	casein kinase 1, delta b	0.016
spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.016
ihhb	Indian hedgehog homolog b	0.016
htra1a	HtrA serine peptidase 1a	0.016
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.016
sp2	sp2 transcription factor	0.016
ldb2a	LIM-domain binding factor 2a	0.016
foxd5	forkhead box D5	0.015
has3	hyaluronan synthase 3	0.015
pdx1	pancreatic and duodenal homeobox 1	0.015
vax1	ventral anterior homeobox 1	0.015
veph	ventricular zone expressed PH domain protein	0.015
fn1	fibronectin 1	0.015
spry4	sprouty (Drosophila) homolog 4	0.015
bon	bonnie and clyde	0.015
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015
foxb1.2	forkhead box B1.2	0.015
ids	iduronate 2-sulfatase	0.015
zgc:92590	zgc:92590	0.014
mapk12	mitogen-activated protein kinase 12	0.014
foxo3b	forkhead box O3b	0.014
myf6	myogenic factor 6	0.014
mapk4	mitogen-activated protein kinase 4	0.014
elk4	ELK4, ETS-domain protein	0.014
zgc:158603	zgc:158603	0.014
twist1b	twist1b	0.014
gata4	GATA-binding protein 4	0.014
hoxb1a	homeo box B1a	0.014
egr2b	early growth response 2b	0.014
mapk1	mitogen-activated protein kinase 1	0.014
sept7b	septin 7b	0.014
hoxc1a	homeo box C1a	0.014
e2f5	E2F transcription factor 5	0.014
frem3	Fras1 related extracellular matrix 3	0.014
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.014
onecutl	one cut domain, family member, like	0.013
gbx1	gastrulation brain homeobox 1	0.013
runx2a	runt-related transcription factor 2a	0.013
mc5rb	melanocortin 5b receptor	0.013
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.013
ryk	receptor-like tyrosine kinase	0.013
fes	feline sarcoma oncogene	0.013
gja3	gap junction protein, alpha 3	0.013
arl4ab	ADP-ribosylation factor-like 4ab	0.013
sfrp2	secreted frizzled-related protein 2	0.013
foxj1a	forkhead box J1a	0.013
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.013
cfl2l	cofilin 2, like	0.013
bhlhe41	basic helix-loop-helix family, member e41	0.013
zfpm1	zinc finger protein, multitype 1	0.012
lrrc6	leucine rich repeat containing 6	0.012
klf4a	Kruppel-like transcription factor 4a	0.012
ier2	immediate early response 2	0.012
mesp2	mesoderm posterior 2 homolog (mouse)	0.012
sox4b	SRY-box containing gene 4b	0.012
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.012
dzip1	DAZ interacting protein 1	0.012
hoxb2a	homeo box B2a	0.012
rnf41	ring finger protein 41	0.012
itgav	integrin, alpha V	0.012
gnb1b	guanine nucleotide binding protein (G protein), beta polypeptide 1b	0.012
araf	v-raf murine sarcoma 3611 viral oncogene homolog	0.011
tp73	tumor protein p73	0.011
ppp4cb	protein phosphatase 4 (formerly X), catalytic subunit b	0.011
nog2	noggin 2	0.011
sema3aa	semaphorin 3aa	0.011
npnt	nephronectin	0.011
bcl2	B-cell leukemia/lymphoma 2	0.011
osr2	odd-skipped related 2 (Drosophila)	0.011
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.011
tob1a	transducer of ERBB2, 1a	0.011
dazl	daz-like gene	0.011
tbx18	T-box 18	0.011
mc4r	melanocortin 4 receptor	0.011
plagl2	pleiomorphic adenoma gene-like 2	0.011
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.011
anxa4	annexin A4	0.011
atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.011
tef	thyrotroph embryonic factor	0.011
chd	chordin	0.011
LOC100535061	meiosis inhibitor protein 1-like	0.011
jag1b	jagged 1b	0.010
si:dkeyp-15g12.1	si:dkeyp-15g12.1	0.010
rfng	radical fringe homolog (Drosophila)	0.010
cenph	centromere protein H	0.010
col5a3b	collagen type V alpha-3b	0.010
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.010
vax2	ventral anterior homeobox 2	0.010