IMP

Process View

Danio rerio

14 genes annotated in zebrafish

bmp signaling pathway involved in determination of left right symmetry

A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "bmp signaling pathway involved in determination of left right symmetry"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "bmp signaling pathway involved in determination of left right symmetry" (in gray)

Name	Description	Probability	Func Analog Organism
tbx16	T-box gene 16	0.996
bmp2b	bone morphogenetic protein 2b	0.992	Zebrafish
tbx1	T-box 1	0.942	Zebrafish
ndr2	nodal-related 2	0.940
shha	sonic hedgehog a	0.917
foxh1	forkhead box H1	0.916
lft2	lefty2	0.915
ntla	no tail a	0.880
flh	floating head	0.862
tbx18	T-box 18	0.848	Zebrafish
sox32	SRY-box containing gene 32	0.813
tbx20	T-box 20	0.758	Zebrafish
chd	chordin	0.739
bmp4	bone morphogenetic protein 4	0.729
admp	anti-dorsalizing morphogenic protein	0.704	Zebrafish
dharma	dharma	0.685
ndr1	nodal-related 1	0.673	Zebrafish
oep	one-eyed pinhead	0.665
her7	hairy and enhancer of split related-7	0.636
ptch1	patched 1	0.591
sox17	SRY-box containing gene 17	0.516
lft1	lefty1	0.503
twist3	twist3	0.479
fn1	fibronectin 1	0.444
tbx2a	T-box gene 2a	0.375	Zebrafish
tll1	tolloid-like 1	0.348
bon	bonnie and clyde	0.348
foxi1	forkhead box I1	0.344
snai1b	snail homolog 1b (Drosophila)	0.340
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.320
nkx1.2la	NK1 transcription factor related 2-like,a	0.313
pcdh8	protocadherin 8	0.301
pkd2	polycystic kidney disease 2	0.293
wnt5b	wingless-type MMTV integration site family, member 5b	0.263
vent	ventral expressed homeobox	0.262
nkx2.5	NK2 transcription factor related 5	0.253
bmp7a	bone morphogenetic protein 7a	0.249
hoxa13b	homeo box A13b	0.217
mespa	mesoderm posterior a	0.210
tbx24	T-box 24	0.205	Zebrafish
hoxd11a	homeo box D11a	0.191
tbx2b	T-box 2b	0.166	Zebrafish
gli1	GLI-Kruppel family member 1	0.156
foxd5	forkhead box D5	0.151
dkk1b	dickkopf 1b	0.150
ptch2	patched 2	0.146
msxc	muscle segment homeobox C	0.135
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.134
hoxa11a	homeo box A11a	0.130
mib	mind bomb	0.130
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.127
ved	ventrally expressed dharma/bozozok antagonist	0.118
hand2	heart and neural crest derivatives expressed transcript 2	0.113
fzd5	frizzled homolog 5	0.109
gpc4	glypican 4	0.108
szl	sizzled	0.107
col8a1a	collagen, type VIII, alpha 1a	0.105
dlx2a	distal-less homeobox gene 2a	0.103
barx1	BarH-like homeobox 1	0.102
gpr126	G protein-coupled receptor 126	0.099
lhx1b	LIM homeobox 1b	0.091
hoxa11b	homeo box A11b	0.089
bmp2a	bone morphogenetic protein 2a	0.089	Zebrafish
cldng	claudin g	0.086
og9x	OG9 homeobox gene	0.080
hapln1a	hyaluronan and proteoglycan link protein 1a	0.079
tbx5a	T-box 5a	0.077	Zebrafish
hoxa9b	homeo box A9b	0.073
msxe	muscle segment homeobox E	0.073
lhx1a	LIM homeobox 1a	0.072
evx1	even-skipped homeobox 1	0.071
rx3	retinal homeobox gene 3	0.068
ephb3a	eph receptor B3a	0.067
axin1	axin 1	0.067
cdx4	caudal type homeo box transcription factor 4	0.066
im:7165141	im:7165141	0.063
smo	smoothened homolog (Drosophila)	0.062
fgf10a	fibroblast growth factor 10a	0.062
smad9	MAD homolog 9 (Drosophila)	0.057	Zebrafish
mespb	mesoderm posterior b	0.056
has2	hyaluronan synthase 2	0.056
gata4	GATA-binding protein 4	0.051
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.051
six4a	sine oculis homeobox homolog 4a	0.048
spaw	southpaw	0.047
foxa2	forkhead box A2	0.047
hoxa10b	homeo box A10b	0.047
wnt10a	wingless-type MMTV integration site family, member 10a	0.046
prdm1a	PR domain containing 1a, with ZNF domain	0.046
spon2a	spondin 2a, extracellular matrix protein	0.045
grem2	gremlin 2, cysteine knot superfamily	0.042
sim2	single-minded homolog 2 (Drosophila)	0.041
gbx2	gastrulation brain homeo box 2	0.040
gsc	goosecoid	0.039	Zebrafish
acvr1b	activin A receptor, type IB	0.037
ephb4b	eph receptor B4b	0.036
msgn1	mesogenin 1	0.035
hoxd13a	homeo box D13a	0.035
hoxd10a	homeo box D10a	0.034
her1	hairy-related 1	0.034
lhx2b	LIM homeobox 2b	0.033
pax9	paired box gene 9	0.033
cldnd	claudin d	0.032
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.032
twist1a	twist1a	0.031
fgf4	fibroblast growth factor 4	0.029
six4b	sine oculis homeobox homolog 4b	0.029
msxd	muscle segment homeobox D	0.029
col27a1a	collagen, type XXVII, alpha 1a	0.029
hoxd12a	homeo box D12a	0.028
rxrbb	retinoid x receptor, beta b	0.028
fzd8b	frizzled homolog 8b	0.028
epb4.1l4	erythrocyte protein band 4.1-like 4	0.027
brd4	bromodomain containing 4	0.027
otx1a	orthodenticle homolog 1a	0.027
s1pr2	sphingosine-1-phosphate receptor 2	0.027
atoh7	atonal homolog 7	0.026
eve1	even-skipped-like1	0.026
cdh2	cadherin 2, neuronal	0.025
ihha	Indian hedgehog homolog a	0.024	Zebrafish
frzb	frizzled-related protein	0.024
twist1b	twist1b	0.024
fbln1	fibulin 1	0.024
lrrc50	leucine rich repeat containing 50	0.024
osr2	odd-skipped related 2 (Drosophila)	0.024
sall4	sal-like 4 (Drosophila)	0.023
fgfr4	fibroblast growth factor receptor 4	0.023
hmx4	H6 family homeobox 4	0.023
hoxa13a	homeo box A13a	0.023
epha4b	eph receptor A4b	0.023
efnb3b	ephrin B3b	0.022
pitx2	paired-like homeodomain transcription factor 2	0.022
gli2a	GLI-Kruppel family member GLI2a	0.022
msxb	muscle segment homeobox B	0.022
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.022
her5	hairy-related 5	0.021
npy8ar	neuropeptide Y receptor Y8a	0.021
gatsl2	GATS protein-like 2	0.021
mxtx2	mix-type homeobox gene 2	0.021
rarga	retinoic acid receptor gamma a	0.021
foxa3	forkhead box A3	0.021
robo3	roundabout homolog 3	0.020
hoxc1a	homeo box C1a	0.020
disp1	dispatched homolog 1 (Drosophila)	0.020
foxd3	forkhead box D3	0.020
vax2	ventral anterior homeobox 2	0.019
zgc:111821	zgc:111821	0.019
rest	RE1-silencing transcription factor	0.019
oprm1	opioid receptor, mu 1	0.019
apln	apelin	0.019
fzd9b	frizzled homolog 9b	0.018
gata6	GATA-binding protein 6	0.018
lef1	lymphocyte enhancer binding factor 1	0.018
nanos3	nanos homolog 3	0.018
sox9b	SRY-box containing gene 9b	0.018
fgf17	fibroblast growth factor 17	0.017
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.017
tbx6	T-box gene 6	0.017	Zebrafish
runx2b	runt-related transcription factor 2b	0.017
and1	actinodin1	0.016
dusp6	dual specificity phosphatase 6	0.016
six3b	sine oculis homeobox homolog 3b	0.016
cdkl1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.016
lrrc6	leucine rich repeat containing 6	0.016
wnt11	wingless-type MMTV integration site family, member 11	0.016
igf1rb	insulin-like growth factor 1b receptor	0.015
ncor1	nuclear receptor co-repressor 1	0.015
nkx2.3	NK2 transcription factor related 3	0.015
sox9a	SRY-box containing gene 9a	0.015
hoxa1a	homeo box A1a	0.014
nkx3.2	NK3 homeobox 2	0.014
tgfb2	transforming growth factor, beta 2	0.014
wif1	wnt inhibitory factor 1	0.013
fezf2	FEZ family zinc finger 2	0.013
lmo4a	LIM domain only 4a	0.013
hoxd4a	homeo box D4a	0.013
gdf6b	growth differentiation factor 6b	0.013	Zebrafish
prrx1b	paired related homeobox 1b	0.012
birc5b	baculoviral IAP repeat-containing 5B	0.012
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.012
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.012
si:ch211-173o4.2	si:ch211-173o4.2	0.012
hhex	hematopoietically expressed homeobox	0.012
mab21l2	mab-21-like 2	0.012
pggt1b	protein geranylgeranyltransferase type I, beta subunit	0.012
plcg1	phospholipase C, gamma 1	0.012
gro1	groucho 1	0.011
sf3b1	splicing factor 3b, subunit 1	0.011
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.011
hoxc10a	homeo box C10a and homeobox protein Hox-C10a-like	0.011
gli2b	GLI-Kruppel family member GLI2b	0.011
lhx5	LIM homeobox 5	0.011
sp5l	Sp5 transcription factor-like	0.011
rargb	retinoic acid receptor, gamma b	0.011
ripply1	ripply1	0.011
lhx3	LIM homeobox 3	0.011
wu:fk76c08	wu:fk76c08	0.010
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.010
tbx5b	T-box 5b	0.010
nkd1	naked cuticle homolog 1 (Drosophila)	0.010