IMP

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Danio rerio

18 genes annotated in zebrafish

cyclic nucleotide metabolic process

The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cyclic nucleotide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cyclic nucleotide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
uts1	urotensin 1	0.977
mc4r	melanocortin 4 receptor	0.910
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.665
adra2db	adrenergic, alpha-2D-, receptor b	0.624
gucy2f	guanylate cyclase 2F, retinal	0.581
nf1a	neurofibromin 1a	0.543	Mouse Fly
adrb2a	adrenergic receptor, beta 2a	0.526
vipr2	vasoactive intestinal peptide receptor 2	0.490	Zebrafish
cyp11b2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.476
calm1a	calmodulin 1a	0.469	Human
mc2r	melanocortin 2 receptor	0.400
drd2b	dopamine receptor D2b	0.391	Human Rat
wu:fv91b12	wu:fv91b12	0.304
osr1	odd-skipped related 1 (Drosophila)	0.261
atp6v0cb	ATPase, H+ transporting, lysosomal, V0 subunit c, b	0.255
adra2c	adrenergic, alpha-2C-, receptor	0.248
mchr1a	melanin-concentrating hormone receptor 1a	0.247
otpa	orthopedia homolog a	0.240
LOC559201	similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)	0.240
cacnb4a	calcium channel, voltage-dependent, beta 4a subunit	0.239	Mouse
mc1r	melanocortin 1 receptor	0.239	Zebrafish
avpl	arginine vasopressin-like	0.233	Mouse
crhbp	corticotropin releasing hormone binding protein	0.221
dbh	dopamine beta hydroxylase	0.220
guca1c	guanylate cyclase activator 1C	0.218
hmgb1a	high-mobility group box 1a	0.217
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.203
adra2b	adrenergic, alpha-2B-, receptor	0.176
inka1a	induced in neural crest by AP2, 1a	0.176
alx4a	aristaless-like homeobox 4a	0.175
ar	androgen receptor	0.159
palm	paralemmin	0.151	Mouse
flj13639	flj13639	0.142
calm2a	calmodulin 2a (phosphorylase kinase, delta)	0.139
xpo4	exportin 4	0.139
pak1	p21/Cdc42/Rac1-activated kinase 1	0.137
nf1b	neurofibromin 1b	0.134	Mouse Fly
drd3	dopamine receptor D3	0.131	Human Rat
slc25a3a	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a	0.131
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.128
adra2a	adrenergic, alpha-2A-, receptor	0.126
cx27.5	connexin 27.5	0.123
mstnb	myostatin b	0.117
gnrh2	gonadotropin-releasing hormone 2	0.113
adcyap1a	adenylate cyclase activating polypeptide 1a	0.110	Human Mouse
fshr	follicle stimulating hormone receptor	0.095
th2	tyrosine hydroxylase 2	0.092
adra2da	adrenergic, alpha-2D-, receptor a	0.092
ros1	v-ros UR2 sarcoma virus oncogene homolog 1 (avian)	0.092
mc5rb	melanocortin 5b receptor	0.091	Human
zgc:110179	zgc:110179	0.091
LOC100332193	growth hormone secretagogue receptor type 1-like	0.088
sox4b	SRY-box containing gene 4b	0.085
nrl	neural retina leucine zipper	0.082
bsk146	brain specific kinase 146	0.080
igf1	insulin-like growth factor 1	0.076
mchr1b	melanin-concentrating hormone receptor 1b	0.074
pp	pyrophosphatase (inorganic)	0.074
paqr8	progestin and adipoQ receptor family member VIII	0.071
adora2b	adenosine A2b receptor	0.069	Mouse Rat
sst1.1	somatostatin 1, tandem duplicate 1	0.067
gdnf	glial cell derived neurotrophic factor	0.067
opn1lw1	opsin 1 (cone pigments), long-wave-sensitive, 1	0.067
gc2	guanylyl cyclase 2	0.066	Zebrafish Rat
fes	feline sarcoma oncogene	0.066
rag1	recombination activating gene 1	0.065
calcrla	calcitonin receptor-like a	0.064	Zebrafish
dharma	dharma	0.063
kif5c	kinesin family member 5C	0.063
atp2b1a	ATPase, Ca++ transporting, plasma membrane 1a	0.062
adcyap1r1a	adenylate cyclase activating polypeptide 1 receptor 1a	0.061
gsdf	gonadal somatic cell derived factor	0.060
opn4l	opsin 4, like	0.055
adipoql	adiponectin, C1Q and collagen domain containing, like	0.054
cldn2	claudin 2	0.053
zgc:77123	zgc:77123	0.052
pde6c	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.052
tert	telomerase reverse transcriptase	0.051
furinb	furin (paired basic amino acid cleaving enzyme) b	0.050
npy8br	neuropeptide Y receptor Y8b	0.050
rargb	retinoic acid receptor, gamma b	0.049
rtn1a	reticulon 1a	0.049
vegfab	vascular endothelial growth factor Ab	0.049	Human
si:ch211-209p5.2	si:ch211-209p5.2	0.049
chrm2a	cholinergic receptor, muscarinic 2a	0.048
gja3	gap junction protein, alpha 3	0.048
cps1	carbamoyl-phosphate synthase 1, mitochondrial	0.047
crabp1a	cellular retinoic acid binding protein 1a	0.046
pcdh17	protocadherin 17	0.046
ptpra	protein tyrosine phosphatase, receptor type, A	0.044
mpp5b	membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b)	0.044
oxtl	oxytocin-like	0.043	Mouse
slc8a4b	solute carrier family 8 (sodium/calcium exchanger), member 4b	0.042
rs1	retinoschisis (X-linked, juvenile) 1	0.042
clstn1	calsyntenin 1	0.042
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.042
plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3	0.042
tspan7b	tetraspanin 7b	0.041
flot2a	flotillin 2a	0.041
si:dkey-228g21.4	si:dkey-228g21.4	0.040
LOC569642	hypothetical protein LOC569642	0.039
sst3	somatostatin 3	0.039
pth2	parathyroid hormone 2	0.039
hcrtr2	hypocretin (orexin) receptor 2	0.039
LOC799612	prolactin 2	0.039
ift46	intraflagellar transport protein 46	0.039
appb	amyloid beta (A4) precursor protein b	0.038
kif5bb	kinesin family member 5B, b	0.038
rxrab	retinoid x receptor, alpha b	0.038
cx52.6	connexin 52.6	0.038
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.037
rras2	related RAS viral (r-ras) oncogene homolog 2	0.037	Yeast
cacnb2a	calcium channel, voltage-dependent, beta 2a	0.037
gnat1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.035
pnrc2	proline-rich nuclear receptor coactivator 2	0.035
ncam2	neural cell adhesion molecule 2	0.034
dclk2	doublecortin-like kinase 2	0.034
mapk1	mitogen-activated protein kinase 1	0.033
drgx	dorsal root ganglia homeobox	0.033
ucn3l	urocortin 3, like	0.033
ptn	pleiotrophin	0.032
mogat2	monoacylglycerol O-acyltransferase 2	0.032
chrnb3b	cholinergic receptor, nicotinic, beta polypeptide 3b	0.031
fgf20b	fibroblast growth factor 20b	0.031
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.031
pyya	peptide YYa	0.030
lifrb	leukemia inhibitory factor receptor alpha b	0.030
or107-1	odorant receptor, family D, subfamily 107, member 1	0.030
saga	S-antigen; retina and pineal gland (arrestin) a	0.030
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.029
npy4r	neuropeptide Y receptor Y4	0.029
oprd1a	opioid receptor, delta 1a	0.029
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.029
mc3r	melanocortin 3 receptor	0.028	Human Zebrafish
zgc:65851	zgc:65851	0.028
mef2a	myocyte enhancer factor 2a	0.028
drd2l	dopamine receptor D2 like	0.028
fermt2	fermitin family homolog 2 (Drosophila)	0.028
cadm2a	cell adhesion molecule 2a	0.027
slc1a2a	solute carrier family 1 (glial high affinity glutamate transporter), member 2a	0.027
rogdi	rogdi homolog (Drosophila)	0.026
si:ch211-14k19.8	si:ch211-14k19.8	0.026
mmd2	progestin and adipoQ receptor 10	0.026
calcr	calcitonin receptor	0.025
slc25a20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	0.025
pax3a	paired box gene 3a	0.025
wnt10b	wingless-type MMTV integration site family, member 10b	0.024
s1pr2	sphingosine-1-phosphate receptor 2	0.024
ywhag1	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1	0.024
twist1b	twist1b	0.024
cacnb4b	calcium channel, voltage-dependent, beta 4b subunit	0.024	Mouse
c1ql4l	complement component 1, q subcomponent-like 4 like	0.024
nt5e	5'-nucleotidase, ecto (CD73)	0.023
kiss1rb	KISS1 receptor b	0.023
disc1	disrupted in schizophrenia 1	0.023
zgc:77752	zgc:77752	0.023
zgc:56548	zgc:56548	0.023
crygs1	crystallin, gamma S1	0.023
thrb	thyroid hormone receptor beta	0.022
zgc:73155	zgc:73155	0.022
drd2a	dopamine receptor D2a	0.022	Human Rat
optc	opticin	0.021
smtnb	smoothelin b	0.021
msi2a	musashi homolog 2a (Drosophila)	0.021
mcamb	melanoma cell adhesion molecule b	0.021
cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.021
bhlha15	basic helix-loop-helix family, member a15	0.021
pmch	pro-melanin concentrating hormone	0.021
slc22a7b	solute carrier family 22 (organic anion transporter), member 7b	0.021
or115-15	odorant receptor, family F, subfamily 115, member 15	0.020
spry2	sprouty homolog 2	0.020
gulp1	GULP, engulfment adaptor PTB domain containing 1	0.020
irx2a	iroquois homeobox protein 2, a	0.020
npy8ar	neuropeptide Y receptor Y8a	0.020
si:ch211-197h24.9	si:ch211-197h24.9	0.019
nrip1b	nuclear receptor interacting protein 1b	0.019
ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B	0.019
pdca	phosducin a	0.019
htr1ab	5-hydroxytryptamine (serotonin) receptor 1A b	0.019	Zebrafish
dhrs3b	dehydrogenase/reductase (SDR family) member 3b	0.019
ahi1	Abelson helper integration site 1	0.019
hdc	histidine decarboxylase	0.019
tgfbi	transforming growth factor, beta-induced	0.019
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.019
gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.018
gap43	growth associated protein 43	0.018
hpca	hippocalcin	0.018
nyx	nyctalopin	0.018
cpla2	cytosolic phospholipase a2	0.018
hnf4a	hepatocyte nuclear factor 4, alpha	0.018
LOC100150924	DNA polymerase subunit gamma-1-like	0.018
syt5a	synaptotagmin Va	0.018
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.018
frzb	frizzled-related protein	0.018
mcf2l	MCF.2 cell line derived transforming sequence-like and mcf.2 cell line derived transforming sequence-like	0.017
LOC555504	novel protocadherin protein	0.017
cx55.5	connexin 55.5	0.017
neurog3	neurogenin 3	0.017
grid2	glutamate receptor, ionotropic, delta 2	0.017
bbs2	Bardet-Biedl syndrome 2	0.016
cyp1d1	cytochrome P450, family 1, subfamily D, polypeptide 1	0.016
gc3	guanylyl cyclase 3	0.016	Zebrafish Rat
cyb5r4	cytochrome b5 reductase 4	0.016
arl6	ADP-ribosylation factor-like 6	0.016
zgc:158234	zgc:158234	0.016
hrh3	histamine receptor H3	0.016
rgs4	regulator of G-protein signalling 4	0.016
sps2	selenophosphate synthetase 2	0.016
npb	neuropeptide B	0.016
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.016
antxr2a	anthrax toxin receptor 2a	0.016
sema6dl	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like	0.016
cart1	cartilage paired-class homeoprotein 1	0.016
stmn1a	stathmin 1a	0.016
bmp8a	bone morphogenetic protein 8a	0.015
tbx20	T-box 20	0.015
tpm4	tropomyosin 4	0.015
mapk15	mitogen-activated protein kinase 15	0.015
rps2	ribosomal protein S2	0.015
uts2b	urotensin 2, beta	0.015
mpz	myelin protein zero	0.015
vegfaa	vascular endothelial growth factor Aa	0.015
crygs2	crystallin, gamma S2	0.015
dchs1	dachsous 1 (Drosophila)	0.015
lrig3	leucine-rich repeats and immunoglobulin-like domains 3	0.015
inha	inhibin, alpha	0.015
bbs5	Bardet-Biedl syndrome 5	0.014
snrk1	SNF related kinase 1	0.014
c1qtnf4	C1q and tumor necrosis factor related protein 4	0.014
grk7a	G-protein-coupled receptor kinase 7a	0.014
mtnr1ba	melatonin receptor type 1B a	0.014	Rat
clrn1	clarin 1	0.014
ca8	carbonic anhydrase VIII	0.014
adrb1	adrenergic receptor, beta 1	0.014	Human Zebrafish Rat
ahr1a	aryl hydrocarbon receptor 1a	0.014
chat	choline acetyltransferase	0.014
fzd7a	frizzled homolog 7a	0.014
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.014
pdlim3a	PDZ and LIM domain 3a	0.014
igfbp6b	insulin-like growth factor binding protein 6b	0.014
aqp7	aquaporin 7	0.013
angptl1	angiopoietin-like 1	0.013
edn1	endothelin 1	0.013
sagb	S-antigen; retina and pineal gland (arrestin) b	0.013
rbp4l	retinol binding protein 4, like	0.013
rx1	retinal homeobox gene 1	0.013
tcea2	transcription elongation factor A (SII), 2	0.013
zgc:110796	zgc:110796	0.013
zgc:63633	zgc:63633	0.013
inhbab	inhibin, beta Ab	0.013
opn1mw4	opsin 1 (cone pigments), medium-wave-sensitive, 4	0.013
has3	hyaluronan synthase 3	0.013
bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	0.013
cnr2	cannabinoid receptor 2	0.013
zdhhc15b	zinc finger, DHHC domain containing 15b	0.013
dzip1	DAZ interacting protein 1	0.013
slc18a3b	solute carrier family 18 (vesicular acetylcholine), member 3b	0.013
ehd1	EH-domain containing 1	0.013
zgc:162213	zgc:162213	0.013
vdac3	voltage-dependent anion channel 3	0.013
irbp	interphotoreceptor retinoid-binding protein	0.013
guk1	guanylate kinase 1	0.013
pufa	PUF (Pumilio/FBF) domain-containing A	0.013
ctgf	connective tissue growth factor	0.013
opn1mw1	opsin 1 (cone pigments), medium-wave-sensitive, 1	0.013
gabra6a	gamma-aminobutyric acid (GABA) A receptor, alpha 6a	0.012
zgc:63907	zgc:63907	0.012
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.012
slc6a4b	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4B	0.012
extl3	exostoses (multiple)-like 3	0.012
arfip2b	ADP-ribosylation factor interacting protein 2b	0.012
agtr2	angiotensin II receptor, type 2	0.012
mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent)	0.012
calca	calcitonin/calcitonin-related polypeptide, alpha	0.012	Mouse
diaph2	diaphanous homolog 2 (Drosophila)	0.012
zgc:152982	zgc:152982	0.012
zgc:136902	zgc:136902	0.012
camk2d2	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2	0.012
zgc:91926	zgc:91926	0.012
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.012
crb2b	crumbs homolog 2b	0.012
kal1a	Kallmann syndrome 1a sequence	0.012
bmp3	bone morphogenetic protein 3	0.012
penka	proenkephalin a	0.012
emp2	epithelial membrane protein 2	0.012
grk1b	G protein-coupled receptor kinase 1 b	0.012
mtnr1bb	melatonin receptor 1B b and melatonin receptor 1B	0.012
kirrelb	kin of IRRE like b	0.012
ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.012
im:7137180	im:7137180	0.012
prdm15	PR domain containing 15	0.012
hoxa1a	homeo box A1a	0.011
vip	vasoactive intestinal peptide	0.011
klf7l	Kruppel-like factor 7 (ubiquitous), like	0.011
tm9sf2	transmembrane 9 superfamily member 2	0.011
atp1a1b	ATPase, Na+/K+ transporting, alpha 1b polypeptide	0.011
vipr1	vasoactive intestinal peptide receptor 1	0.011	Zebrafish
LOC559147	novel protein similar to vertebrate hairy and enhancer of split 2 (Drosophila) (HES2)	0.011
fabp7b	fatty acid binding protein 7, brain, b	0.011
pth1b	parathyroid hormone 1b	0.011
slit1b	slit homolog 1b (Drosophila)	0.011
dusp5	dual specificity phosphatase 5	0.011
cx43	connexin 43	0.011
nlgn1	neuroligin 1	0.011
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.011
tuba7l	tubulin, alpha 7 like	0.011
arl4ab	ADP-ribosylation factor-like 4ab	0.011
akap12b	A kinase (PRKA) anchor protein (gravin) 12b	0.011
gpd1b	glycerol-3-phosphate dehydrogenase 1b	0.011
kpnb3	karyopherin (importin) beta 3	0.011
fkbp5	FK506 binding protein 5	0.011
rab28	RAB28, member RAS oncogene family	0.011
LOC100006249	carbohydrate sulfotransferase 2-like	0.011
fam53b	family with sequence similarity 53, member B	0.011
ryr2a	ryanodine receptor 2a (cardiac)	0.011
npffl	neuropeptide FF-amide peptide precursor like	0.011
wisp1b	WNT1 inducible signaling pathway protein 1b	0.011
ctsba	cathepsin B, a	0.011
gpd2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.011
decr1	2,4-dienoyl CoA reductase 1, mitochondrial	0.011
defbl3	defensin, beta-like 3	0.011
pdlim3b	PDZ and LIM domain 3b	0.011
si:dkey-37m8.9	si:dkey-37m8.9	0.011
cbsa	cystathionine-beta-synthase a	0.011	Mouse
rcv1	recoverin	0.011
or115-10	odorant receptor, family F, subfamily 115, member 10	0.010
exorh	extra-ocular rhodopsin	0.010
rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.010
si:dkeyp-72g9.4	si:dkeyp-72g9.4	0.010
cldn15a	claudin 15a	0.010
cebpg	CCAAT/enhancer binding protein (C/EBP), gamma	0.010
mmp15a	matrix metallopeptidase 15a	0.010
igfbp6a	insulin-like growth factor binding protein 6a	0.010
ttc39c	tetratricopeptide repeat domain 39C	0.010
sept6	septin 6	0.010
rab3ip	RAB3A interacting protein (rabin3)	0.010