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Danio rerio

16 genes annotated in zebrafish

pituitary gland development

GO:0021983

The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pituitary gland development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pituitary gland development" (in gray)

Name	Description	Probability	Func Analog Organism
shha	sonic hedgehog a	1.000
fgf8a	fibroblast growth factor 8 a	0.998	Mouse
fgf3	fibroblast growth factor 3	0.997
bmp4	bone morphogenetic protein 4	0.994	Mouse
eya1	eyes absent homolog 1	0.983
rx3	retinal homeobox gene 3	0.979
tbx1	T-box 1	0.975
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.965
sox2	SRY-box containing gene 2	0.964	Human Mouse
pax2a	paired box gene 2a	0.963
nkx2.2a	NK2 transcription factor related 2a	0.929
tfap2a	transcription factor AP-2 alpha	0.928
dla	deltaA	0.928
dld	deltaD	0.890
gli1	GLI-Kruppel family member 1	0.833
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.833
foxi1	forkhead box I1	0.829
mib	mind bomb	0.824
pitx2	paired-like homeodomain transcription factor 2	0.747	Zebrafish Mouse
notch1a	notch homolog 1a	0.735
ntla	no tail a	0.723
prdm1a	PR domain containing 1a, with ZNF domain	0.676
foxa2	forkhead box A2	0.654
six3a	sine oculis homeobox homolog 3a	0.603	Zebrafish
foxd3	forkhead box D3	0.555
cdh2	cadherin 2, neuronal	0.525
foxg1a	forkhead box G1a	0.525
dlx3b	distal-less homeobox gene 3b	0.484
gli2a	GLI-Kruppel family member GLI2a	0.484
dkk1b	dickkopf 1b	0.481
six1b	sine oculis homeobox homolog 1b	0.479
bmp2b	bone morphogenetic protein 2b	0.478	Mouse
dzip1	DAZ interacting protein 1	0.472
dbx1a	developing brain homeobox 1a	0.435
flh	floating head	0.423
fezf2	FEZ family zinc finger 2	0.423
six3b	sine oculis homeobox homolog 3b	0.384	Zebrafish Mouse
dlx2a	distal-less homeobox gene 2a	0.380
six4a	sine oculis homeobox homolog 4a	0.352
nkx2.1a	NK2 homeobox 1a	0.351
msxc	muscle segment homeobox C	0.333
otpb	orthopedia homolog b	0.320
ndr2	nodal-related 2	0.296
sox3	SRY-box containing gene 3	0.263	Mouse
grhl2b	grainyhead-like 2b (Drosophila)	0.254
pou1f1	POU domain, class 1, transcription factor 1	0.242	Mouse Rat
pcdh8	protocadherin 8	0.226
dlx4b	distal-less homeobox gene 4b	0.224
rx2	retinal homeobox gene 2	0.223	Zebrafish
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.213
foxe3	forkhead box E3	0.213
hmx4	H6 family homeobox 4	0.208
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.202
twist3	twist3	0.194
otx2	orthodenticle homolog 2	0.187
fzd8a	frizzled homolog 8a	0.177
nos1	nitric oxide synthase 1 (neuronal)	0.174
klf4	Kruppel-like factor 4	0.164
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.159
chd	chordin	0.155
lhx5	LIM homeobox 5	0.144
wnt11	wingless-type MMTV integration site family, member 11	0.144
ptch2	patched 2	0.137
arx	aristaless related homeobox	0.131
pax6a	paired box gene 6a	0.130	Mouse
tp63	tumor protein p63	0.125
wnt5b	wingless-type MMTV integration site family, member 5b	0.124	Mouse
foxd5	forkhead box D5	0.122
dlc	deltaC	0.121
irx1b	iroquois homeobox protein 1, b	0.121
pax6b	paired box gene 6b	0.119	Mouse
hoxb1b	homeo box B1b	0.116
otx1b	orthodenticle homolog 1b	0.115
lhx6	LIM homeobox 6	0.115
extl3	exostoses (multiple)-like 3	0.111
sox17	SRY-box containing gene 17	0.107
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.105
emx1	empty spiracles homeobox 1	0.102
gbx2	gastrulation brain homeo box 2	0.102
ptch1	patched 1	0.101
gli2b	GLI-Kruppel family member GLI2b	0.097
gsc	goosecoid	0.096
msgn1	mesogenin 1	0.096
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.095
sox19a	SRY-box containing gene 19a	0.089
nkx2.2b	NK2 transcription factor related 2b	0.085
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.082
pitx3	paired-like homeodomain transcription factor 3	0.081
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.078
lhx1a	LIM homeobox 1a	0.076
dlx5a	distal-less homeobox gene 5a	0.075
tll1	tolloid-like 1	0.074
szl	sizzled	0.072
lhx2b	LIM homeobox 2b	0.070
pax8	paired box gene 8	0.069
foxa3	forkhead box A3	0.066
otpa	orthopedia homolog a	0.065
gbx1	gastrulation brain homeobox 1	0.065
neurod	neurogenic differentiation	0.064
neurog1	neurogenin 1	0.064
prl	prolactin	0.061
shhb	sonic hedgehog b	0.061	Zebrafish
alpi	alkaline phosphatase, intestinal	0.060
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.058
phox2a	paired-like homeobox 2a	0.057
wnt8b	wingless-type MMTV integration site family, member 8b	0.055
her5	hairy-related 5	0.054
olig2	oligodendrocyte lineage transcription factor 2	0.052
spon2a	spondin 2a, extracellular matrix protein	0.052
myod1	myogenic differentiation 1	0.050
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.050
sp5l	Sp5 transcription factor-like	0.049
tg	thyroglobulin	0.048
snapc1b	small nuclear RNA activating complex, polypeptide 1b	0.047
tbx24	T-box 24	0.046
sox1a	SRY-box containing gene 1a	0.045
pea3	ETS-domain transcription factor pea3	0.043
nkx2.5	NK2 transcription factor related 5	0.043
sfrp5	secreted frizzled-related protein 5	0.042
dlb	deltaB	0.041
gata3	GATA-binding protein 3	0.041
eve1	even-skipped-like1	0.040
sfrp1a	secreted frizzled-related protein 1a	0.040
mab21l2	mab-21-like 2	0.040
six4b	sine oculis homeobox homolog 4b	0.039	Zebrafish
hhip	hedgehog interacting protein	0.038
ildr1b	immunoglobulin-like domain containing receptor 1b	0.038
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.038
hoxa2b	homeo box A2b	0.038
mmp15b	matrix metallopeptidase 15b	0.037
lef1	lymphocyte enhancer binding factor 1	0.036
vax2	ventral anterior homeobox 2	0.035
tp53	tumor protein p53	0.034
bmp2a	bone morphogenetic protein 2a	0.034	Mouse
pld1a	phospholipase D1a	0.034
rnasel1	ribonuclease like 1	0.034
fzd10	frizzled homolog 10	0.034
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.033
hnf1ba	HNF1 homeobox Ba	0.033
dlx2b	distal-less homeobox gene 2b	0.033
tjp1	tight junction protein 1 (zona occludens 1)	0.032
fgf8b	fibroblast growth factor 8 b	0.031	Mouse
dlx4a	distal-less homeobox gene 4a	0.031
nr1i2	nuclear receptor subfamily 1, group I, member 2	0.030
tbx16	T-box gene 16	0.029
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.028
dlx1a	distal-less homeobox gene 1a	0.028
prdm14	PR domain containing 14	0.027
gfra1b	gdnf family receptor alpha 1b	0.027
fgf20a	fibroblast growth factor 20a	0.026	Zebrafish
col8a1a	collagen, type VIII, alpha 1a	0.026
atoh1a	atonal homolog 1a	0.026
her3	hairy-related 3	0.026
pitx1	paired-like homeodomain transcription factor 1	0.025	Zebrafish Mouse
irx1a	iroquois homeobox protein 1, a	0.025
wnt1	wingless-type MMTV integration site family, member 1	0.025
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.025
insm1a	insulinoma-associated 1a	0.025
tfe3b	transcription factor binding to IGHM enhancer 3b	0.024
emx3	empty spiracles homeobox 3	0.024
axin1	axin 1	0.023
vax1	ventral anterior homeobox 1	0.023
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.023
foxa1	forkhead box A1	0.023
hnf1a	HNF1 homeobox a	0.022
dharma	dharma	0.022
wnt3	wingless-type MMTV integration site family, member 3	0.021
fgfr1a	fibroblast growth factor receptor 1a	0.021
lfng	lunatic fringe homolog	0.020
gpc4	glypican 4	0.020
esrrgb	estrogen-related receptor gamma b	0.019
otx1a	orthodenticle homolog 1a	0.019
barhl2	BarH-like 2	0.019
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.018
tbx22	T-box 22	0.018
fzd8b	frizzled homolog 8b	0.018
irx7	iroquois homeobox protein 7	0.018
neurod4	neurogenic differentiation 4	0.018
cga	glycoprotein hormones, alpha polypeptide	0.018
bambib	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b	0.017
sp7	Sp7 transcription factor	0.017
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.017
pxn	paxillin	0.017
phox2b	paired-like homeobox 2b	0.017
odz4	odd Oz/ten-m homolog 4	0.017
vsx2	visual system homeobox 2	0.017
jag1b	jagged 1b	0.017
lingo1b	leucine rich repeat and Ig domain containing 1b	0.017
smad1	MAD homolog 1 (Drosophila)	0.016
runx2a	runt-related transcription factor 2a	0.016
pax4	paired box 4	0.016
gdf6b	growth differentiation factor 6b	0.016
anxa5b	annexin A5b	0.016
efnb3b	ephrin B3b	0.016
krt4	keratin 4	0.015
hesx1	homeo box (expressed in ES cells) 1	0.015	Zebrafish
irx3a	iroquois homeobox protein 3a	0.015
gata2a	GATA-binding protein 2a	0.015	Mouse
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.015
bmper	BMP binding endothelial regulator	0.014
gle1	GLE1 RNA export mediator homolog (yeast)	0.014
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.014
fgfr4	fibroblast growth factor receptor 4	0.014
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.014
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.014
cx30.3	connexin 30.3	0.013
hoxd4a	homeo box D4a	0.013
cdx4	caudal type homeo box transcription factor 4	0.013
nort	notch-regulated transcript	0.013
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.013	Rat
rx1	retinal homeobox gene 1	0.013	Zebrafish
sox9a	SRY-box containing gene 9a	0.013
drd4-rs	dopamine receptor D4 related sequence	0.013
hoxb5b	homeo box B5b	0.013
lhx1b	LIM homeobox 1b	0.013
gata4	GATA-binding protein 4	0.013
epha7	eph receptor A7	0.013
met	met proto-oncogene (hepatocyte growth factor receptor)	0.012
zgc:101606	zgc:101606	0.012
hoxa9a	homeo box A9a	0.012
lft2	lefty2	0.012
hoxa3a	homeo box A3a	0.012
hmx3	homeo box (H6 family) 3	0.012
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.012
sox32	SRY-box containing gene 32	0.012
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.012
zgc:65851	zgc:65851	0.012
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.012
fgf4	fibroblast growth factor 4	0.012	Zebrafish
boc	brother of CDO	0.011
efnb2b	ephrin B2b	0.011
clint1	clathrin interactor 1	0.011
dio2	deiodinase, iodothyronine, type II	0.011
foxb1.1	forkhead box B1.1	0.011
lhx3	LIM homeobox 3	0.011
nkx2.1b	NK2 homeobox 1b	0.011	Mouse
pkd2	polycystic kidney disease 2	0.011
msxa	muscle segment homeobox A	0.010
cdh10	cadherin 10, type 2 (T2-cadherin)	0.010
ldb2b	LIM-domain binding factor 2b	0.010
bon	bonnie and clyde	0.010
foxn4	forkhead box N4	0.010
slit1b	slit homolog 1b (Drosophila)	0.010
pomca	proopiomelanocortin a	0.010
asb11	ankyrin repeat and SOCS box-containing 11	0.010
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.010
gdf6a	growth differentiation factor 6a	0.010
ptmab	prothymosin, alpha b	0.010
msxb	muscle segment homeobox B	0.010