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Danio rerio

19 genes annotated in zebrafish

autonomic nervous system development

The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "autonomic nervous system development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "autonomic nervous system development" (in gray)

Name	Description	Probability	Func Analog Organism
crestin	crestin	0.983
phox2a	paired-like homeobox 2a	0.983	Zebrafish Mouse
foxd3	forkhead box D3	0.947
dla	deltaA	0.935
eya1	eyes absent homolog 1	0.838
sox10	SRY-box containing gene 10	0.813
hoxb3a	homeo box B3a	0.788
cntn2	contactin 2	0.756
foxi1	forkhead box I1	0.756	Zebrafish
nkx2.3	NK2 transcription factor related 3	0.750
sema3d	semaphorin 3d	0.741
nadl1.1	neural adhesion molecule L1.1	0.567
gli2a	GLI-Kruppel family member GLI2a	0.546	Zebrafish
wu:fv91b12	wu:fv91b12	0.493
nrp1b	neuropilin 1b	0.484	Mouse
hoxb2a	homeo box B2a	0.472	Zebrafish Mouse
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.446
egr2b	early growth response 2b	0.439	Mouse
lef1	lymphocyte enhancer binding factor 1	0.430
pcdh18b	protocadherin 18b	0.422
six1b	sine oculis homeobox homolog 1b	0.413	Mouse
gfra1a	gdnf family receptor alpha 1a	0.395
tfap2a	transcription factor AP-2 alpha	0.390	Mouse
tp53	tumor protein p53	0.365
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.361
six3a	sine oculis homeobox homolog 3a	0.343
nrp1a	neuropilin 1a	0.316	Mouse
hoxa2b	homeo box A2b	0.308	Zebrafish
bmper	BMP binding endothelial regulator	0.290
prrx1b	paired related homeobox 1b	0.289	Zebrafish
hoxb6a	homeo box B6a	0.266
phox2b	paired-like homeobox 2b	0.257
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.255
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.245
hoxb1a	homeo box B1a	0.236
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.234
irx3a	iroquois homeobox protein 3a	0.218
tfe3b	transcription factor binding to IGHM enhancer 3b	0.215
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.211
tfec	transcription factor EC	0.205
foxa1	forkhead box A1	0.196	Zebrafish
tlx2	T-cell leukemia, homeobox 2	0.185
edn1	endothelin 1	0.182
nkx3.2	NK3 homeobox 2	0.181
neurog1	neurogenin 1	0.177
prickle1b	prickle homolog 1 (Drosophila) b	0.174
disp1	dispatched homolog 1 (Drosophila)	0.173
gcm2	glial cells missing homolog 2 (Drosophila)	0.156
neurod	neurogenic differentiation	0.149
hoxb1b	homeo box B1b	0.138	Zebrafish Mouse
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.136
isl2a	islet2a	0.135
nrp2b	neuropilin 2b	0.133	Mouse
nes	nestin	0.130
insm1a	insulinoma-associated 1a	0.129
twist1a	twist1a	0.129
tbx1	T-box 1	0.123	Mouse
olig2	oligodendrocyte lineage transcription factor 2	0.121
sumo2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.120
six4a	sine oculis homeobox homolog 4a	0.120
dlb	deltaB	0.119
notch1a	notch homolog 1a	0.118
ret1	receptor tyrosine kinase	0.115
pax7a	paired box gene 7a	0.111
drgx	dorsal root ganglia homeobox	0.110	Zebrafish
emx3	empty spiracles homeobox 3	0.110
mab21l2	mab-21-like 2	0.109
dld	deltaD	0.105
plxna3	plexin A3	0.102	Mouse
irx4b	iroquois homeobox protein 4b	0.099
gata3	GATA-binding protein 3	0.098	Mouse
mecom	MDS1 and EVI1 complex locus	0.092
cdh4	cadherin 4, retinal	0.090
rest	RE1-silencing transcription factor	0.088
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.087
lhx5	LIM homeobox 5	0.086
otx2	orthodenticle homolog 2	0.084
flh	floating head	0.084
hoxa3a	homeo box A3a	0.082
six2a	sine oculis-related homeobox 2a	0.077
jag1b	jagged 1b	0.076
six4b	sine oculis homeobox homolog 4b	0.076
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.076
nrp2a	neuropilin 2a	0.073	Mouse
sox19a	SRY-box containing gene 19a	0.073
grhl1	grainyhead-like 1 (Drosophila)	0.073
zic4	zic family member 4	0.069
barx1	BarH-like homeobox 1	0.069
twist1b	twist1b	0.069
hoxb5b	homeo box B5b	0.068
tcf21	transcription factor 21	0.067
hoxd11a	homeo box D11a	0.066
dlx4b	distal-less homeobox gene 4b	0.066
pax9	paired box gene 9	0.066
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.065
vangl2	vang-like 2 (van gogh, Drosophila)	0.065
pax2a	paired box gene 2a	0.065
runx3	runt-related transcription factor 3	0.065
dlx6a	distal-less homeobox gene 6a	0.064
dzip1	DAZ interacting protein 1	0.062
rhag	Rhesus blood group-associated glycoprotein	0.059
fgf10a	fibroblast growth factor 10a	0.058
grhl2b	grainyhead-like 2b (Drosophila)	0.058
ndr2	nodal-related 2	0.058
slc16a10	solute carrier family 16, member 10 (aromatic amino acid transporter)	0.056
lama1	laminin, alpha 1	0.055
gfra1b	gdnf family receptor alpha 1b	0.055
gli1	GLI-Kruppel family member 1	0.052
sox2	SRY-box containing gene 2	0.051
mib	mind bomb	0.050
ebf3	early B-cell factor 3	0.049
dlx1a	distal-less homeobox gene 1a	0.049
gbx2	gastrulation brain homeo box 2	0.048	Mouse
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.047
hoxb5a	homeo box B5a	0.046
grem2	gremlin 2, cysteine knot superfamily	0.045
atoh8	atonal homolog 8	0.045
sema3gb	semaphorin 3gb	0.045
tbx15	T-box 15	0.045
fgf5	fibroblast growth factor 5	0.044
pcdh19	protocadherin 19	0.044
flot1	flotillin 1	0.044
zgc:77051	zgc:77051	0.044
bhlhe22	basic helix-loop-helix family, member e22	0.043
ltk	leukocyte tyrosine kinase	0.042
p2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.041
nos1	nitric oxide synthase 1 (neuronal)	0.041
hmx3	homeo box (H6 family) 3	0.040
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.040
eng2a	engrailed 2a	0.040
rx2	retinal homeobox gene 2	0.039
nhsl1b	NHS-like 1b	0.039
hoxa4a	homeo box A4a	0.038
brpf1	bromodomain and PHD finger containing, 1	0.038
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.037
kbp	kif1-binding protein	0.037
sox1a	SRY-box containing gene 1a	0.037
ptpra	protein tyrosine phosphatase, receptor type, A	0.037
dpysl2b	dihydropyrimidinase-like 2b	0.035
jam2b	junctional adhesion molecule 2b	0.034
ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B	0.034
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.034
raraa	retinoic acid receptor, alpha a	0.034
pitx3	paired-like homeodomain transcription factor 3	0.034
msxb	muscle segment homeobox B	0.034
zeb2b	zinc finger E-box binding homeobox 2b	0.033
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.033
ahi1	Abelson helper integration site 1	0.032
unc5b	unc-5 homolog B (C. elegans)	0.032
olig3	oligodendrocyte transcription factor 3	0.031
gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.031
barx2	BarH-like homeobox 2	0.031
pcdh17	protocadherin 17	0.030
hand2	heart and neural crest derivatives expressed transcript 2	0.030	Mouse
tal2	T-cell acute lymphocytic leukemia 2	0.029
zgc:112180	zgc:112180	0.029
dmrta2	doublesex and mab-3 related transcription factor like family A2	0.029
tp63	tumor protein p63	0.029	Mouse
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.029
trpa1b	transient receptor potential cation channel, subfamily A, member 1b	0.029
twist3	twist3	0.029
fgf20b	fibroblast growth factor 20b	0.028
klf7	Kruppel-like factor 7 (ubiquitous)	0.028
dct	dopachrome tautomerase	0.028
zgc:113312	zgc:113312	0.027
nog2	noggin 2	0.027
hoxd13a	homeo box D13a	0.027
fsta	follistatin a	0.026
snai1b	snail homolog 1b (Drosophila)	0.026
rad21	RAD21 homolog (S. pombe)	0.026
tbx2b	T-box 2b	0.026
pou1f1	POU domain, class 1, transcription factor 1	0.025
nrg1	neuregulin 1	0.025
puf60a	poly-U binding splicing factor a	0.025
nkx6.2	NK6 transcription factor related, locus 2	0.025
her8a	hairy-related 8a	0.025
pcdh10a	protocadherin 10a	0.025
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.024
otx1b	orthodenticle homolog 1b	0.024
trpv4	transient receptor potential cation channel, subfamily V, member 4	0.023
zic6	zic family member 6	0.023
dlx5a	distal-less homeobox gene 5a	0.023
dusp5	dual specificity phosphatase 5	0.023
trpv1	transient receptor potential cation channel subfamily V member 1	0.023
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.023
sema3fb	semaphorin 3fb	0.023	Mouse
dachb	dachshund b	0.023
dlx2a	distal-less homeobox gene 2a	0.023
cbfb	core-binding factor, beta subunit	0.022
tfap2b	transcription factor AP-2 beta	0.022	Mouse
frem3	Fras1 related extracellular matrix 3	0.022
insm1b	insulinoma-associated 1b	0.022	Mouse
foxa2	forkhead box A2	0.022	Zebrafish
nrxn2a	neurexin 2a	0.022
irx5b	iroquois homeobox protein 5b	0.022
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.022
mapta	microtubule-associated protein tau a	0.022
axin1	axin 1	0.022
drd2l	dopamine receptor D2 like	0.021
tuba1	tubulin, alpha 1	0.021
shha	sonic hedgehog a	0.021
pitx1	paired-like homeodomain transcription factor 1	0.021
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.020
isl1	islet1	0.020
cadm1a	cell adhesion molecule 1a	0.020
satb2	SATB homeobox 2	0.020
bmp6	bone morphogenetic protein 6	0.020
tsc2	tuberous sclerosis 2	0.020
pax3b	paired box gene 3b	0.019
irx1a	iroquois homeobox protein 1, a	0.019
prdm5	PR domain containing 5	0.019
otpa	orthopedia homolog a	0.019
ca2	carbonic anhydrase II	0.019
lzts2a	leucine zipper, putative tumor suppressor 2a	0.019
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.019
rtn4a	reticulon 4a	0.019
zgc:85942	zgc:85942	0.019
ryr1b	ryanodine receptor 1b (skeletal)	0.018
fbxw7	F-box and WD repeat domain containing 7	0.018
plagx	pleiomorphic adenoma gene X	0.018
sim2	single-minded homolog 2 (Drosophila)	0.018
efna2	ephrin A2	0.018
plxnb2b	plexin b2b	0.018
fgf13b	fibroblast growth factor 13b	0.018
scn1ba	sodium channel, voltage-gated, type I, beta a	0.018
cap1	Cap1 CAP, adenylate cyclase-associated protein 1	0.018
gsc	goosecoid	0.018
lhx3	LIM homeobox 3	0.017
klhl31	kelch-like 31 (Drosophila)	0.017
antxr1	anthrax toxin receptor 1	0.017
sp8a	sp8 transcription factor a	0.017
meis3	myeloid ecotropic viral integration site 3	0.017
cadm4	cell adhesion molecule 4	0.017
irx5a	iroquois homeobox protein 5a	0.017
sox4b	SRY-box containing gene 4b	0.017
vegfc	vascular endothelial growth factor c	0.017
mab21l1	mab-21-like 1	0.017
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.017
ncapg2	non-SMC condensin II complex, subunit G2	0.016
epha7	eph receptor A7	0.016
sema3c	semaphorin 3c	0.016
cnr1	cannabinoid receptor 1	0.016
helt	hey-like transcription factor	0.016
fzd7a	frizzled homolog 7a	0.016
dlx3b	distal-less homeobox gene 3b	0.016
sim1a	single-minded homolog 1a (Drosophila)	0.016
gdf6a	growth differentiation factor 6a	0.016
prpf8	pre-mRNA processing factor 8	0.016
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.016
LOC557062	hypothetical protein LOC557062	0.016
boc	brother of CDO	0.016
sema3aa	semaphorin 3aa	0.016	Mouse
inka1a	induced in neural crest by AP2, 1a	0.016
p2rx3b	purinergic receptor P2X, ligand-gated ion channel, 3b	0.016
phf21a	PHD finger protein 21A	0.016
ppp1r14ab	protein phosphatase 1, regulatory (inhibitor) subunit 14Ab	0.015
hoxa10b	homeo box A10b	0.015
lbx1a	ladybird homeobox 1a	0.015
eng2b	engrailed 2b	0.015
celf1	cugbp, Elav-like family member 1	0.015
zgc:194131	zgc:194131	0.015
emx2	empty spiracles homeobox 2	0.015
dao.2	D-amino-acid oxidase 2	0.015
ek1	eph-like kinase 1	0.015
cenph	centromere protein H	0.015
gc2	guanylyl cyclase 2	0.015
avpr1b	arginine vasopressin receptor 1B	0.015
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.015
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.015
loxl2b	lysyl oxidase-like 2b	0.015
adipoql2	adiponectin, C1Q and collagen domain containing, like 2	0.014
chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.014
efnb1	ephrin B1	0.014
prrx1a	paired related homeobox 1a	0.014	Zebrafish
crb2a	crumbs homolog 2a	0.014
m17	IL-6 subfamily cytokine M17	0.014
col9a2	procollagen, type IX, alpha 2	0.014
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.014
otpb	orthopedia homolog b	0.014
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.014
fzd3a	frizzled homolog 3a	0.014	Mouse
rx3	retinal homeobox gene 3	0.014
prkcz	protein kinase C, zeta	0.014
hoxa13b	homeo box A13b	0.014
fgfrl1b	fibroblast growth factor receptor-like 1b	0.014
myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.013
hoxd10a	homeo box D10a	0.013
prdm14	PR domain containing 14	0.013
ache	acetylcholinesterase	0.013
id:ibd2050	id:ibd2050	0.013
mnx1	motor neuron and pancreas homeobox 1	0.013
hoxd12a	homeo box D12a	0.013
dnmt6	DNA (cytosine-5-)-methyltransferase 6	0.013
prox1b	prospero-related homeobox gene 1b	0.013
eng1b	engrailed 1b	0.013
zgc:158350	zgc:158350	0.012
uts1	urotensin 1	0.012
dixdc1a	DIX domain containing 1a	0.012
stmn2b	stathmin-like 2b	0.012
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.012
adora2b	adenosine A2b receptor	0.012
gsx1	GS homeobox 1	0.012
plxna4	plexin A4	0.012	Mouse
sema3ga	semaphorin 3ga	0.012
pou3f3b	POU class 3 homeobox 3b	0.012
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.012
nos2b	nitric oxide synthase 2b, inducible	0.012
zgc:110124	zgc:110124	0.012
fign	fidgetin	0.012
egr2a	early growth response 2a	0.012	Mouse
nkx2.1b	NK2 homeobox 1b	0.011
olfm2	olfactomedin 2	0.011
fn1	fibronectin 1	0.011
wu:fq26c12	wu:fq26c12	0.011
gdf11	growth differentiation factor 11	0.011
slc4a4b	solute carrier family 4, sodium bicarbonate cotransporter, member 4b	0.011
agtr2	angiotensin II receptor, type 2	0.011
angpt1	angiopoietin 1	0.011
meis2.2	myeloid ecotropic viral integration site 2.2	0.011
scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.011
rac3a	ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3)	0.011
lmo4a	LIM domain only 4a	0.011
hoxc11a	homeo box C11a	0.011
nav3	neuron navigator 3	0.011
pbx4	pre-B-cell leukemia transcription factor 4	0.011
zgc:91787	zgc:91787	0.011
sox21b	SRY-box containing gene 21 b	0.011
cdh10	cadherin 10, type 2 (T2-cadherin)	0.011
hlxb9lb	homeo box HB9 like b	0.011
fabp7a	fatty acid binding protein 7, brain, a	0.011
drd4-rs	dopamine receptor D4 related sequence	0.011
si:ch211-212m21.5	si:ch211-212m21.5	0.011
tbx18	T-box 18	0.011
flrt1b	fibronectin leucine rich transmembrane 1b	0.011
chrna6	cholinergic receptor, nicotinic, alpha 6	0.011
hoxc1a	homeo box C1a	0.011	Zebrafish
ntn1b	netrin 1b	0.011
foxp2	forkhead box P2	0.011
tgfbr1b	transforming growth factor, beta receptor 1 b	0.011
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.011
rxrga	retinoid x receptor, gamma a	0.011
spry1	sprouty homolog 1 (Drosophila)	0.010
smyhc1l	slow myosin heavy chain 1, like	0.010
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.010
pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	0.010
penkb	proenkephalin b	0.010
mpped2	metallophosphoesterase domain containing 2	0.010
kcnj13	potassium inwardly-rectifying channel, subfamily J, member 13	0.010
sox21a	SRY-box containing gene 21a	0.010