IMP

Process View

Danio rerio

14 genes annotated in zebrafish

response to alcohol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to alcohol"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to alcohol" (in gray)

Name	Description	Probability	Func Analog Organism
apoeb	apolipoprotein Eb	0.481
shha	sonic hedgehog a	0.413
inhbaa	inhibin, beta Aa	0.389	Rat
socs3a	suppressor of cytokine signaling 3a	0.375	Rat
nrp2b	neuropilin 2b	0.313
sox11a	SRY-box containing gene 11a	0.199
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.178	Rat
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.143
col1a1a	collagen, type I, alpha 1a	0.142	Rat
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.136
ptprf	protein tyrosine phosphatase, receptor type, F	0.089
otx2	orthodenticle homolog 2	0.089
dag1	dystroglycan 1	0.081
dcn	decorin	0.077
gpr126	G protein-coupled receptor 126	0.075
acvr2a	activin receptor IIa	0.073
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.072
esrrga	estrogen-related receptor gamma a	0.070	Zebrafish
uts1	urotensin 1	0.070
esr1	estrogen receptor 1	0.068
per2	period homolog 2 (Drosophila)	0.066
ca2	carbonic anhydrase II	0.061
evx1	even-skipped homeobox 1	0.061
alcama	activated leukocyte cell adhesion molecule a	0.057
igf3	insulin-like growth factor 3	0.055
gdf11	growth differentiation factor 11	0.054
cbr1l	carbonyl reductase 1-like	0.053
cyp3a65	cytochrome P450, family 3, subfamily A, polypeptide 65	0.052
itgb1a	integrin, beta 1a	0.050
robo2	roundabout homolog 2	0.050
pcna	proliferating cell nuclear antigen	0.049
gcm2	glial cells missing homolog 2 (Drosophila)	0.048
ctsba	cathepsin B, a	0.048	Rat
mao	monoamine oxidase	0.045
dab1a	disabled homolog 1a (Drosophila)	0.045
ca8	carbonic anhydrase VIII	0.045
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.044
fzd7a	frizzled homolog 7a	0.044
chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1	0.041
pdia4	protein disulfide isomerase associated 4	0.040
rc3	rabconnectin 3	0.040
igf2b	insulin-like growth factor 2b	0.039	Rat
paqr7b	progestin and adipoQ receptor family member VII, b	0.038
pcp4a	Purkinje cell protein 4a	0.038
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.038
ripk2	receptor-interacting serine-threonine kinase 2	0.037
cry1a	cryptochrome 1a	0.037
spry4	sprouty (Drosophila) homolog 4	0.037
inha	inhibin, alpha	0.037
cadm1b	cell adhesion molecule 1b	0.037
cry3	cryptochrome 3	0.037
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.036
chrm2a	cholinergic receptor, muscarinic 2a	0.035
fgf3	fibroblast growth factor 3	0.035
bcl2	B-cell leukemia/lymphoma 2	0.034	Rat
sept9a	septin 9a	0.034
tgfbr2	transforming growth factor, beta receptor II	0.033	Human Mouse
hsp90a.1	heat shock protein 90-alpha 1	0.033
mmp9	matrix metalloproteinase 9	0.032
gdf9	growth differentiation factor 9	0.032
bcl2l1	bcl2-like 1	0.031
foxi1	forkhead box I1	0.031
mmp2	matrix metalloproteinase 2	0.031
gfra1a	gdnf family receptor alpha 1a	0.031
myca	myelocytomatosis oncogene a	0.030
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.030
th2	tyrosine hydroxylase 2	0.030
zgc:85866	zgc:85866	0.030
mapk1	mitogen-activated protein kinase 1	0.030	Fly
epas1b	endothelial PAS domain protein 1b	0.029
ahi1	Abelson helper integration site 1	0.029
nrg1	neuregulin 1	0.028
robo3	roundabout homolog 3	0.028
calr	calreticulin and calreticulin	0.028	Worm
th	tyrosine hydroxylase	0.027	Rat
ctsz	cathepsin Z	0.027
glud1a	glutamate dehydrogenase 1a	0.027
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.027
nr1d1	nuclear receptor subfamily 1, group d, member 1	0.027	Fly
mef2d	myocyte enhancer factor 2d	0.026
junb	jun B proto-oncogene	0.025
fzd8b	frizzled homolog 8b	0.025
avpl	arginine vasopressin-like	0.025	Rat
wnt10a	wingless-type MMTV integration site family, member 10a	0.025
kif5c	kinesin family member 5C	0.025
ptgs1	prostaglandin-endoperoxide synthase 1	0.025	Rat
slit3	slit (Drosophila) homolog 3	0.025	Human
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.025	Rat
bhmt	betaine-homocysteine methyltransferase	0.025
tfap2a	transcription factor AP-2 alpha	0.025
lhx3	LIM homeobox 3	0.024
chrna4	cholinergic receptor, nicotinic, alpha 4	0.024
fgfr4	fibroblast growth factor receptor 4	0.024
zgc:153997	zgc:153997	0.024
zbtb10	zinc finger and BTB domain containing 10	0.024
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.024
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.024
dbh	dopamine beta hydroxylase	0.023	Mouse
quo	quattro	0.023
wif1	wnt inhibitory factor 1	0.023
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.022
pax8	paired box gene 8	0.022
klf4	Kruppel-like factor 4	0.022
myog	myogenin	0.022	Mouse
lamb1a	laminin, beta 1a	0.022
oxtl	oxytocin-like	0.022	Rat
satb2	SATB homeobox 2	0.021
atf3	activating transcription factor 3	0.021
irx2a	iroquois homeobox protein 2, a	0.021
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.021
stat3	signal transduction and activation of transcription 3	0.020	Human Rat
nr1d2b	nuclear receptor subfamily 1, group D, member 2b	0.020	Fly
arx	aristaless related homeobox	0.020
tp53bp2	tumor protein p53 binding protein, 2	0.020
gdnf	glial cell derived neurotrophic factor	0.020	Rat
ptger2a	prostaglandin E receptor 2a (subtype EP2)	0.020
zgc:77714	zgc:77714	0.020
igfbp1a	insulin-like growth factor binding protein 1a	0.020
whsc1	Wolf-Hirschhorn syndrome candidate 1	0.020
wu:fc18f06	wu:fc18f06	0.020
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.020
jun	jun proto-oncogene	0.020
nadl1.2	neural adhesion molecule L1.2	0.019	Rat
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.019	Fly
junbl	jun B proto-oncogene, like	0.019
nkx2.1a	NK2 homeobox 1a	0.019
ptprk	protein tyrosine phosphatase, receptor type, K	0.019
eno3	enolase 3, (beta, muscle)	0.019
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.019
ephb3a	eph receptor B3a	0.019
yap1	Yes-associated protein 1	0.019
nkd2	naked cuticle homolog 2 and naked 2a	0.019
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.019
ar	androgen receptor	0.019	Zebrafish
ctrl	chymotrypsin-like	0.019
pvrl1b	poliovirus receptor-related 1b	0.019
adra2c	adrenergic, alpha-2C-, receptor	0.018
odc1	ornithine decarboxylase 1	0.018
dyx1c1	dyslexia susceptibility 1 candidate 1	0.018
mapk3	mitogen-activated protein kinase 3	0.018	Fly
pcdh10a	protocadherin 10a	0.018
ccnb1	cyclin B1	0.018
acvr2b	activin receptor IIb	0.018
hspb11	heat shock protein, alpha-crystallin-related, b11	0.018
dsc2l	desmocollin 2 like	0.017
rspo1	R-spondin homolog (Xenopus laevis)	0.017
drd2a	dopamine receptor D2a	0.017	Mouse Rat
col12a1	collagen, type XII, alpha 1	0.017
bmp3	bone morphogenetic protein 3	0.017
il1b	interleukin 1, beta and interleukin 1, beta	0.017
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.017
il6st	interleukin 6 signal transducer	0.017
mmp13a	matrix metalloproteinase 13a	0.016
igf1	insulin-like growth factor 1	0.016
hyou1	hypoxia up-regulated 1	0.016
ccnd1	cyclin D1	0.016	Rat
ckma	creatine kinase, muscle a	0.016
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.016
bmp15	bone morphogenetic protein 15	0.016
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.016
rag1	recombination activating gene 1	0.016
drd2b	dopamine receptor D2b	0.016	Mouse Rat
cpla2	cytosolic phospholipase a2	0.016
irx4a	iroquois homeobox protein 4a	0.016
foxa3	forkhead box A3	0.016	Fly
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.016
slc8a4a	solute carrier family 8 (sodium/calcium exchanger), member 4a	0.015
glula	glutamate-ammonia ligase (glutamine synthase) a	0.015
ntrk2a	neurotrophic tyrosine kinase, receptor, type 2a	0.015
rrad	Ras-related associated with diabetes	0.015
hcrt	hypocretin (orexin) neuropeptide precursor	0.015
gnrhr3	gonadotropin releasing hormone receptor 3	0.015
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.015
vcanb	versican b	0.015
im:7164961	im:7164961	0.015
LOC572430	e3 ubiquitin-protein ligase HACE1-like	0.015
rdh12	retinol dehydrogenase 12 (all-trans and 9-cis)	0.015
zgc:110010	zgc:110010	0.015	Rat
ret1	receptor tyrosine kinase	0.015
fosl2	fos-like antigen 2	0.014
reln	reelin	0.014
egr2a	early growth response 2a	0.014
pax2a	paired box gene 2a	0.014
znf503	zinc finger protein 503	0.014
tfap2e	transcription factor AP-2 epsilon	0.014
esr2b	estrogen receptor 2b	0.014	Zebrafish Rat
prom1b	prominin 1 b	0.014
cldn2	claudin 2	0.014
vox	ventral homeobox	0.014
calrl2	calreticulin, like 2	0.014
anxa1b	annexin A1b	0.014
vdra	vitamin D receptor a	0.014
mpx	myeloid-specific peroxidase	0.014
stac3	SH3 and cysteine rich domain 3	0.014
bbc3	BCL2 binding component 3	0.014
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.014
hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.014
clock	clock	0.014
gpr22	G protein-coupled receptor 22	0.014
cdc14aa	CDC14 cell division cycle 14 homolog A, a	0.014
mvp	major vault protein	0.014
drd1	dopamine receptor D1	0.013	Rat
fas	Fas (TNF receptor superfamily, member 6)	0.013
fgf20a	fibroblast growth factor 20a	0.013
zeb2b	zinc finger E-box binding homeobox 2b	0.013
prkcq	protein kinase C, theta	0.013
mpp1	membrane protein, palmitoylated 1	0.013
acta1a	actin, alpha 1a, skeletal muscle	0.013
gro1	groucho 1	0.013
id1	inhibitor of DNA binding 1	0.013
sb:eu2484	sb:eu2484	0.013
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.013
drl	draculin	0.013
nr1d2a	nuclear receptor subfamily 1, group D, member 2a	0.013	Fly
jag1b	jagged 1b	0.013
znf536	zinc finger protein 536	0.013
fes	feline sarcoma oncogene	0.013
evpl	envoplakin	0.013
pdlim1	PDZ and LIM domain 1 (elfin)	0.013
foxe1	forkhead box E1 (thyroid transcription factor 2)	0.013
gas6	growth arrest-specific 6	0.013
esrrb	estrogen-related receptor beta	0.013
wnt8a	wingless-type MMTV integration site family, member 8a	0.013
nrg2a	neuregulin 2a	0.012
npy4r	neuropeptide Y receptor Y4	0.012
fzd7b	frizzled homolog 7b	0.012
twist3	twist3	0.012
zgc:152982	zgc:152982	0.012
stc1l	stanniocalcin 1, like	0.012	Rat
zgc:113210	zgc:113210	0.012
lum	lumican	0.012
zgc:171802	zgc:171802	0.012
nr1d4a	nuclear receptor subfamily 1, group D, member 4a	0.012	Fly
fgf8a	fibroblast growth factor 8 a	0.012
lpp	LIM domain containing preferred translocation partner in lipoma	0.012
itgb1b	integrin, beta 1b	0.012
mc4r	melanocortin 4 receptor	0.012
gfra1b	gdnf family receptor alpha 1b	0.012
ocrl	oculocerebrorenal syndrome of Lowe	0.012
runx1	runt-related transcription factor 1	0.012
lpar1	lysophosphatidic acid receptor 1	0.012
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.012
c1qtnf4	C1q and tumor necrosis factor related protein 4	0.012
egr2b	early growth response 2b	0.012
boc	brother of CDO	0.012
nlgn1	neuroligin 1	0.012
ntrk2b	neurotrophic tyrosine kinase, receptor, type 2b	0.012
paqr8	progestin and adipoQ receptor family member VIII	0.011
gnrh2	gonadotropin-releasing hormone 2	0.011
insra	insulin receptor a	0.011	Rat
dspa	desmoplakin a	0.011
slc16a10	solute carrier family 16, member 10 (aromatic amino acid transporter)	0.011
pycard	PYD and CARD domain containing	0.011
hif1al	hypoxia-inducible factor 1, alpha subunit, like	0.011
card14	caspase recruitment domain family, member 14	0.011
tpp1	tripeptidyl peptidase I	0.011
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.011
irf8	interferon regulatory factor 8	0.011
zgc:56306	zgc:56306	0.011
ctsk	cathepsin K	0.011
thbs4b	thrombospondin 4b	0.011
fbn2b	fibrillin 2b	0.011
dlx5a	distal-less homeobox gene 5a	0.011
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
nkx1.2la	NK1 transcription factor related 2-like,a	0.011
rs1	retinoschisis (X-linked, juvenile) 1	0.011
agr2	anterior gradient homolog 2 (Xenopus laevis)	0.011
smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.011
nt5e	5'-nucleotidase, ecto (CD73)	0.011
ehd2	EH-domain containing 2	0.011
cyp19a1a	cytochrome P450, family 19, subfamily A, polypeptide 1a	0.011
ctrb1	chymotrypsinogen B1	0.011
mos	v-mos Moloney murine sarcoma viral oncogene homolog	0.011
cxcl14	chemokine (C-X-C motif) ligand 14	0.011
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.011
sp8a	sp8 transcription factor a	0.011
sb:cb190	sb:cb190	0.011
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.011
zgc:101797	zgc:101797	0.011
txnrd1	thioredoxin reductase 1	0.011
ptprfb	protein tyrosine phosphatase, receptor type, f, b	0.011
col5a2l	collagen, type V, alpha 2-like	0.011
cnr1	cannabinoid receptor 1	0.011	Rat
lama5	laminin, alpha 5	0.011
me3	malic enzyme 3, NADP(+)-dependent, mitochondrial	0.011
sat1a	spermidine/spermine N1-acetyltransferase 1a	0.011
eno1	enolase 1, (alpha)	0.011
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.011
fzd10	frizzled homolog 10	0.010
zgc:100919	zgc:100919	0.010
zgc:55891	zgc:55891	0.010
irf2bp2a	interferon regulatory factor 2 binding protein 2a	0.010
tal1	T-cell acute lymphocytic leukemia 1	0.010
atp1b2b	ATPase, Na+/K+ transporting, beta 2b polypeptide	0.010
tcf12	transcription factor 12	0.010
sox4b	SRY-box containing gene 4b	0.010
cdk10	cyclin-dependent kinase 10	0.010
rbp1a	retinol binding protein 1a, cellular	0.010
capns1b	calpain, small subunit 1 b	0.010
dsg2	desmoglein 2	0.010