The network for 'positive regulation of dna templated transcription elongation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of dna templated transcription elongation

Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.

Homo sapiens
Name Description Probability Func Analog Organism
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.000
EP300 E1A binding protein p300 1.000
THOC4 THO complex 4 1.000
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.000
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.999
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.999
AFF4 AF4/FMR2 family, member 4 0.998
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.998
CTR9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.994
HDAC4 histone deacetylase 4 0.992
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.990
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.974
CNOT2 CCR4-NOT transcription complex, subunit 2 0.959
THOC5 THO complex 5 0.943
CNOT1 CCR4-NOT transcription complex, subunit 1 0.935
CREBBP CREB binding protein 0.927
TRRAP transformation/transcription domain-associated protein 0.915
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.851
CCNT1 cyclin T1 0.825
TCEA1 transcription elongation factor A (SII), 1 0.815
CNOT8 CCR4-NOT transcription complex, subunit 8 0.807
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.792
SNF8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.764
SMAD3 SMAD family member 3 0.759
TP53 tumor protein p53 0.756
WDR61 WD repeat domain 61 0.743
XAB2 XPA binding protein 2 0.732
EIF4A3 eukaryotic translation initiation factor 4A3 0.716
EAF1 ELL associated factor 1 0.665
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.661
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.605
AFF1 AF4/FMR2 family, member 1 0.552
CDK9 cyclin-dependent kinase 9 0.546
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.536
MED26 mediator complex subunit 26 0.530
HIPK2 homeodomain interacting protein kinase 2 0.502
SMAD2 SMAD family member 2 0.490
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.455
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.435
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.432
NCOA3 nuclear receptor coactivator 3 0.412
CHTOP chromatin target of PRMT1 0.356
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.323
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.293
CNOT3 CCR4-NOT transcription complex, subunit 3 0.281
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.280
STRN4 striatin, calmodulin binding protein 4 0.266
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.265
THOC2 THO complex 2 0.261
BECN1 beclin 1, autophagy related 0.260
CDK2 cyclin-dependent kinase 2 0.242
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.216
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.207
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.200
THOC1 THO complex 1 0.200
ATG14 ATG14 autophagy related 14 homolog (S. cerevisiae) 0.191
KDM2A lysine (K)-specific demethylase 2A 0.187
CHD8 chromodomain helicase DNA binding protein 8 0.183
NCOA1 nuclear receptor coactivator 1 0.177
SRSF2 serine/arginine-rich splicing factor 2 0.177
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.169
CREB1 cAMP responsive element binding protein 1 0.157
CDAN1 congenital dyserythropoietic anemia, type I 0.155
ARID1A AT rich interactive domain 1A (SWI-like) 0.147
MYO6 myosin VI 0.125
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.123
SIRT1 sirtuin 1 0.123
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.120
MED12 mediator complex subunit 12 0.101
MARK3 MAP/microtubule affinity-regulating kinase 3 0.101
HDGF hepatoma-derived growth factor 0.100
CNOT6 CCR4-NOT transcription complex, subunit 6 0.100
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.092
MEF2A myocyte enhancer factor 2A 0.088
MEF2C myocyte enhancer factor 2C 0.088
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.079
ATXN7 ataxin 7 0.077
EWSR1 Ewing sarcoma breakpoint region 1 0.074
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.074
MAPK1 mitogen-activated protein kinase 1 0.074
HABP4 hyaluronan binding protein 4 0.073
MED15 mediator complex subunit 15 0.071
TLK1 tousled-like kinase 1 0.071
SARNP SAP domain containing ribonucleoprotein 0.071
HDAC1 histone deacetylase 1 0.070
TADA2A transcriptional adaptor 2A 0.068
AR androgen receptor 0.064
NCOR1 nuclear receptor corepressor 1 0.063
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.062
USP22 ubiquitin specific peptidase 22 0.061
RUNX1 runt-related transcription factor 1 0.060
UVRAG UV radiation resistance associated gene 0.060
NCOA6 nuclear receptor coactivator 6 0.060
RNF11 ring finger protein 11 0.058
PABPN1 poly(A) binding protein, nuclear 1 0.055
ZNF512B zinc finger protein 512B 0.055
SSRP1 structure specific recognition protein 1 0.054
HDAC9 histone deacetylase 9 0.051
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.050
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.050
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
mef2cb myocyte enhancer factor 2cb 0.374
mib mind bomb 0.294
mef2ca myocyte enhancer factor 2ca 0.259
cand1 cullin-associated and neddylation-dissociated 1 0.126
ola1 Obg-like ATPase 1 0.109
setd8b SET domain containing (lysine methyltransferase) 8b 0.091
sf3b1 splicing factor 3b, subunit 1 0.083
ep300b E1A binding protein p300 b 0.079
ttna titin a 0.076
edn1 endothelin 1 0.075
usp5 ubiquitin specific protease 5 0.061
flncb filamin C, gamma b (actin binding protein 280) 0.060
spns2 spinster homolog 2 (Drosophila) 0.059
papolb poly(A) polymerase beta (testis specific) 0.059
gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 0.054
btg1 B-cell translocation gene 1 0.053
fn1 fibronectin 1 0.050
cct7 chaperonin containing TCP1, subunit 7 (eta) 0.048
prdm2b PR domain containing 2, with ZNF domain b 0.046
pbx4 pre-B-cell leukemia transcription factor 4 0.046
snrpa small nuclear ribonucleoprotein polypeptide A 0.045
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.044
supt6h suppressor of Ty 6 homolog 0.043
srsf6b serine/arginine-rich splicing factor 6b 0.043
hug HuG 0.043
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.043
rbm39a RNA binding motif protein 39a 0.041
spint1a serine peptidase inhibitor, Kunitz type 1 a 0.039
si:ch211-59d15.5 si:ch211-59d15.5 0.039
mll4a myeloid/lymphoid or mixed-lineage leukemia 4a 0.038
psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.038
bcas2 breast carcinoma amplified sequence 2 0.033
safb scaffold attachment factor B 0.033
caprin1a cell cycle associated protein 1a 0.032
cbx1a chromobox homolog 1a (HP1 beta homolog Drosophila) 0.032
ddx42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 0.032
prdm11 PR domain containing 11 0.032
tbx5a T-box 5a 0.031
ulk2 unc-51-like kinase 2 (C. elegans) 0.030
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.030
tbx1 T-box 1 0.030
fam50a family with sequence similarity 50, member A 0.030
psmb5 proteasome (prosome, macropain) subunit, beta type, 5 0.030
tra2b transformer 2 beta homolog (Drosophila) 0.029
wdr82 WD repeat domain containing 82 0.029
ubr5 ubiquitin protein ligase E3 component n-recognin 5 0.028
ripk4 receptor-interacting serine-threonine kinase 4 0.027
brd4 bromodomain containing 4 0.027
disp1 dispatched homolog 1 (Drosophila) 0.027
cdh2 cadherin 2, neuronal 0.027
arrdc1a arrestin domain containing 1a 0.027
ildr1a immunoglobulin-like domain containing receptor 1a 0.027
psma5 proteasome (prosome, macropain) subunit, alpha type,5 0.026
cd151 CD151 molecule 0.026
ilf3a interleukin enhancer binding factor 3a 0.026
sf1 splicing factor 1 0.026
fhl four and a half LIM domains 0.025
atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.025
usp14 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) 0.025
nedd8 neural precursor cell expressed, developmentally down-regulated 8 0.025
h3f3c H3 histone, family 3C 0.024
zgc:56148 zgc:56148 0.024
cx35.4 connexin 35.4 0.024
prdm8b PR domain containing 8b 0.024
taf9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.024
snrnp70 small nuclear ribonucleoprotein 70 (U1) 0.023
smyd5 SMYD family member 5 0.023
morf4l1 mortality factor 4 like 1 0.023
zgc:77304 zgc:77304 0.023
hdac4 histone deacetylase 4 0.023
ankrd13c ankyrin repeat domain 13C 0.023
crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.023
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.023
lpcat4 lysophosphatidylcholine acyltransferase 4 0.023
psmc1a proteasome (prosome, macropain) 26S subunit, ATPase, 1a 0.022
clec14a C-type lectin domain family 14, member A 0.022
dpp3 dipeptidylpeptidase 3 0.022
jam2b junctional adhesion molecule 2b 0.022
ccdc25 coiled-coil domain containing 25 0.022
kdm5bb lysine (K)-specific demethylase 5Bb 0.022
kdm1a lysine (K)-specific demethylase 1a 0.022
mrpl23 mitochondrial ribosomal protein L23 0.021
uck2b uridine-cytidine kinase 2b 0.021
csnk1a1 casein kinase 1, alpha 1 0.021
ctr9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.021
suv420h2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.021
ube2i2 ubiquitin-conjugating enzyme E2I2 0.021
zgc:103692 zgc:103692 0.021
sephs1 selenophosphate synthetase 1 0.021
mll2 myeloid/lymphoid or mixed-lineage leukemia 2 0.021
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.021
rpn2 ribophorin II 0.021
pdcd4a programmed cell death 4a 0.021
zgc:103697 zgc:103697 0.021
nsd1b nuclear receptor binding SET domain protein 1b 0.021
hax1 HCLS1 associated protein X-1 0.021
wdr18 WD repeat domain 18 0.021
xirp1 xin actin-binding repeat containing 1 0.020
ehmt1b euchromatic histone-lysine N-methyltransferase 1b 0.020
suv420h1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.020
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Drosophila melanogaster
Name Description Probability Func Analog Organism
tin tinman 0.026
l(3)01239 lethal (3) 01239 0.019
bin biniou 0.017
Nedd8 CG10679 gene product from transcript CG10679-RA 0.016
twi twist 0.016
east enhanced adult sensory threshold 0.016
CG10333 CG10333 gene product from transcript CG10333-RA 0.016
mib1 mind bomb 1 0.015
RpII215 RNA polymerase II 215kD subunit 0.014
slou slouch 0.012
ash1 absent, small, or homeotic discs 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Trrap transformation/transcription domain-associated protein 0.991
Arid1a AT rich interactive domain 1A (SWI-like) 0.989
Hand1 heart and neural crest derivatives expressed transcript 1 0.968
Foxc1 forkhead box C1 0.952
Prrx1 paired related homeobox 1 0.948
Cdk9 cyclin-dependent kinase 9 (CDC2-related kinase) 0.944
Shh sonic hedgehog 0.942
Hand2 heart and neural crest derivatives expressed transcript 2 0.934
Tcfap2a transcription factor AP-2, alpha 0.881
Crebbp CREB binding protein 0.839
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.825
Msx1 homeobox, msh-like 1 0.822
Foxc2 forkhead box C2 0.800
Eya1 eyes absent 1 homolog (Drosophila) 0.787
Fgfr2 fibroblast growth factor receptor 2 0.785
Sox9 SRY-box containing gene 9 0.757
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.757
Ep400 E1A binding protein p400 0.747
Hdac4 histone deacetylase 4 0.738
Tgfb2 transforming growth factor, beta 2 0.682
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.667
Ncor2 nuclear receptor co-repressor 2 0.658
Msx2 homeobox, msh-like 2 0.639
Bmp4 bone morphogenetic protein 4 0.625
Pcnxl3 pecanex-like 3 (Drosophila) 0.624
Fgf8 fibroblast growth factor 8 0.611
Bmp7 bone morphogenetic protein 7 0.599
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.580
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.571
Mef2d myocyte enhancer factor 2D 0.531
Otx2 orthodenticle homolog 2 (Drosophila) 0.526
Dlx5 distal-less homeobox 5 0.523
Pitx2 paired-like homeodomain transcription factor 2 0.522
Pax3 paired box gene 3 0.515
Rnf44 ring finger protein 44 0.495
Bmp2 bone morphogenetic protein 2 0.484
Isl1 ISL1 transcription factor, LIM/homeodomain 0.482
Ednra endothelin receptor type A 0.473
Wbp7 WW domain binding protein 7 0.460
Acvr1 activin A receptor, type 1 0.456
Arid1b AT rich interactive domain 1B (SWI-like) 0.456
Mef2c myocyte enhancer factor 2C 0.454
Gata4 GATA binding protein 4 0.444
Srrt serrate RNA effector molecule homolog (Arabidopsis) 0.443
Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 0.427
Axin1 axin 1 0.420
Acin1 apoptotic chromatin condensation inducer 1 0.407
Tbx1 T-box 1 0.403
Ewsr1 Ewing sarcoma breakpoint region 1 0.402
Thoc4 THO complex 4 0.391
Hdac5 histone deacetylase 5 0.389
Refbp2 RNA and export factor binding protein 2 0.385
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.374
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.334
Fgfr1 fibroblast growth factor receptor 1 0.332
Zeb1 zinc finger E-box binding homeobox 1 0.298
Safb2 scaffold attachment factor B2 0.292
Jarid2 jumonji, AT rich interactive domain 2 0.289
Hcfc1 host cell factor C1 0.285
Zfp740 zinc finger protein 740 0.278
Crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.275
Bptf bromodomain PHD finger transcription factor 0.265
Tgfbr2 transforming growth factor, beta receptor II 0.263
Atxn7l3 ataxin 7-like 3 0.261
Casc3 cancer susceptibility candidate 3 0.249
Rrp1 ribosomal RNA processing 1 homolog (S. cerevisiae) 0.245
Helz helicase with zinc finger domain 0.231
Rere arginine glutamic acid dipeptide (RE) repeats 0.230
Safb scaffold attachment factor B 0.228
Runx2 runt related transcription factor 2 0.226
Zfp830 zinc finger protein 830 0.219
Brd2 bromodomain containing 2 0.211
Ncdn neurochondrin 0.201
Pabpn1 poly(A) binding protein, nuclear 1 0.199
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.197
Med13l mediator complex subunit 13-like 0.194
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.190
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.180
Polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.179
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.173
Chrd chordin 0.172
Ncoa6 nuclear receptor coactivator 6 0.165
Dmap1 DNA methyltransferase 1-associated protein 1 0.165
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.164
Med12 mediator of RNA polymerase II transcription, subunit 12 homolog (yeast) 0.162
C1d C1D nuclear receptor co-repressor 0.157
Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.153
Prrc2b proline-rich coiled-coil 2B 0.152
Gsc goosecoid homeobox 0.152
Glg1 golgi apparatus protein 1 0.151
Tshz1 teashirt zinc finger family member 1 0.151
Smad7 MAD homolog 7 (Drosophila) 0.148
Zfp598 zinc finger protein 598 0.146
Rnf2 ring finger protein 2 0.144
Klf7 Kruppel-like factor 7 (ubiquitous) 0.142
Uba3 ubiquitin-like modifier activating enzyme 3 0.141
Fbrs fibrosin 0.141
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.140
Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.139
Clk2 CDC-like kinase 2 0.139
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CTR9 Ctr9p 0.969
RTF1 Rtf1p 0.936
CAF40 Caf40p 0.899
MOT2 Mot2p 0.886
CCR4 Ccr4p 0.866
LEO1 Leo1p 0.822
SPT5 Spt5p 0.736
POP2 Pop2p 0.723
NOT5 Not5p 0.716
GBP2 Gbp2p 0.703
CTK3 Ctk3p 0.690
CDC39 Cdc39p 0.686
SPT16 Spt16p 0.609
SWI6 Swi6p 0.556
PAF1 Paf1p 0.548
STE11 Ste11p 0.506
CDC36 Cdc36p 0.439
HMO1 Hmo1p 0.390
DST1 Dst1p 0.375
YKE2 Yke2p 0.355
HHT1 Hht1p 0.344
BTT1 Btt1p 0.299
RAD6 Rad6p 0.234
CTK1 Ctk1p 0.233
VPS38 Vps38p 0.207
SDC1 Sdc1p 0.199
BCK1 Bck1p 0.198
HRP1 Hrp1p 0.187
RPN2 Rpn2p 0.161
MFT1 Mft1p 0.155
SGV1 Sgv1p 0.146
CHD1 Chd1p 0.133
PSY4 Psy4p 0.122
YLR455W hypothetical protein 0.118
DEF1 Def1p 0.116
HPR1 Hpr1p 0.101
NAT1 Nat1p 0.098
CKA1 Cka1p 0.098
CTK2 Ctk2p 0.096
AIR1 Air1p 0.095
SAS4 Sas4p 0.093
LRP1 Lrp1p 0.093
NOT3 Not3p 0.087
RSC4 Rsc4p 0.084
HHO1 Hho1p 0.083
PFD1 Pfd1p 0.081
YPK3 Ypk3p 0.079
SAS5 Sas5p 0.078
SFH1 Sfh1p 0.077
MPT5 Mpt5p 0.074
UME1 Ume1p 0.073
SNF7 Snf7p 0.069
MSG5 Msg5p 0.068
RPB3 Rpb3p 0.067
FKH1 Fkh1p 0.066
PAC10 Pac10p 0.065
SWE1 Swe1p 0.065
SIC1 Sic1p 0.055
SPT8 Spt8p 0.053
SPC110 Spc110p 0.052
SUB1 Sub1p 0.051
STE5 Ste5p 0.050
CKB1 Ckb1p 0.050
SET1 Set1p 0.050
TOP2 Top2p 0.050
RVB2 Rvb2p 0.050
GIM4 Gim4p 0.049
NST1 Nst1p 0.049
VPS15 Vps15p 0.049
MHT1 Mht1p 0.047
CKS1 Cks1p 0.047
HDA2 Hda2p 0.046
YNG1 Yng1p 0.045
RIM1 Rim1p 0.045
NTO1 Nto1p 0.044
EAF6 Eaf6p 0.044
CRZ1 Crz1p 0.042
UBP6 Ubp6p 0.042
SET2 Set2p 0.041
GIM5 Gim5p 0.040
RPT3 Rpt3p 0.040
RXT2 Rxt2p 0.040
ATG21 Atg21p 0.040
SEM1 Sem1p 0.040
VAC17 Vac17p 0.040
CTF8 Ctf8p 0.040
CLB1 Clb1p 0.039
PKC1 Pkc1p 0.039
MSI1 Msi1p 0.039
SSN3 Ssn3p 0.039
PPH3 Pph3p 0.037
ATG14 Atg14p 0.036
YNG2 Yng2p 0.036
BRN1 Brn1p 0.036
TIF4632 Tif4632p 0.036
GLO3 Glo3p 0.036
NPL6 Npl6p 0.035
SPT2 Spt2p 0.035
SRD1 Srd1p 0.035
TYE7 Tye7p 0.034