The network for 'negative regulation of cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.

Homo sapiens
Name Description Probability Func Analog Organism
FN1 fibronectin 1 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.999
JAG1 jagged 1 0.992
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.990
FGFR2 fibroblast growth factor receptor 2 0.982
TEK TEK tyrosine kinase, endothelial 0.970
FLNA filamin A, alpha 0.961
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.954
EGFR epidermal growth factor receptor 0.923
NRP1 neuropilin 1 0.895
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.880
FKBP1A FK506 binding protein 1A, 12kDa 0.877
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.877
NOTCH3 notch 3 0.850
CCR5 chemokine (C-C motif) receptor 5 0.848
C1QA complement component 1, q subcomponent, A chain 0.834
THBS1 thrombospondin 1 0.834
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.833
NOTCH1 notch 1 0.822
RARA retinoic acid receptor, alpha 0.811
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.804
GRB7 growth factor receptor-bound protein 7 0.800
TGFB1 transforming growth factor, beta 1 0.795
IFITM2 interferon induced transmembrane protein 2 (1-8D) 0.786
COL1A1 collagen, type I, alpha 1 0.779
MAPK1 mitogen-activated protein kinase 1 0.771
TBX5 T-box 5 0.768
VEGFA vascular endothelial growth factor A 0.763
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.748
HOXB5 homeobox B5 0.726
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.712
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.704
MET met proto-oncogene (hepatocyte growth factor receptor) 0.691
BMP1 bone morphogenetic protein 1 0.688
BMP2 bone morphogenetic protein 2 0.647
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.643
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.619
ENG endoglin 0.617
DUSP1 dual specificity phosphatase 1 0.593
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.586
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.578
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.558
FGF1 fibroblast growth factor 1 (acidic) 0.555
KRT15 keratin 15 0.535
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.499
PXN paxillin 0.487
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.484
ANGPT2 angiopoietin 2 0.473
STRN3 striatin, calmodulin binding protein 3 0.463
FHL2 four and a half LIM domains 2 0.462
BAIAP2 BAI1-associated protein 2 0.456
COL1A2 collagen, type I, alpha 2 0.451
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.450
A2M alpha-2-macroglobulin 0.446
MEF2A myocyte enhancer factor 2A 0.444
TGFB3 transforming growth factor, beta 3 0.440
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) 0.431
VCAM1 vascular cell adhesion molecule 1 0.427
ABI2 abl-interactor 2 0.420
KRT6B keratin 6B 0.419
SPTBN1 spectrin, beta, non-erythrocytic 1 0.406
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.399
ZYX zyxin 0.394
MYH9 myosin, heavy chain 9, non-muscle 0.385
HOXB6 homeobox B6 0.378
CDH5 cadherin 5, type 2 (vascular endothelium) 0.378
TIMP1 TIMP metallopeptidase inhibitor 1 0.373
FGA fibrinogen alpha chain 0.372
GDF5 growth differentiation factor 5 0.368
ADRB1 adrenergic, beta-1-, receptor 0.365
COL5A1 collagen, type V, alpha 1 0.357
CD63 CD63 molecule 0.354
PTN pleiotrophin 0.354
TIMP3 TIMP metallopeptidase inhibitor 3 0.349
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.348
ADORA2A adenosine A2a receptor 0.346
MEF2C myocyte enhancer factor 2C 0.343
HIPK2 homeodomain interacting protein kinase 2 0.341
STRN4 striatin, calmodulin binding protein 4 0.338
VCAN versican 0.336
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.333
IGF2 insulin-like growth factor 2 (somatomedin A) 0.332
BMPR1B bone morphogenetic protein receptor, type IB 0.329
PLAU plasminogen activator, urokinase 0.323
VIM vimentin 0.321
KRT8 keratin 8 0.318
SFRP1 secreted frizzled-related protein 1 0.318
ANGPTL2 angiopoietin-like 2 0.317
EPHA3 EPH receptor A3 0.315
APOC1 apolipoprotein C-I 0.313
EFNA1 ephrin-A1 0.312
STRN striatin, calmodulin binding protein 0.312
SLMAP sarcolemma associated protein 0.311
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.311
CCL5 chemokine (C-C motif) ligand 5 0.306
SP110 SP110 nuclear body protein 0.304
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.299
IGFBP4 insulin-like growth factor binding protein 4 0.299
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.289
MKL1 megakaryoblastic leukemia (translocation) 1 0.288
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
dlc deltaC 0.727
kdrl kinase insert domain receptor like 0.661
efnb2a ephrin B2a 0.628
dag1 dystroglycan 1 0.577
fgf3 fibroblast growth factor 3 0.566
sulf2l sulfatase 2, like 0.537
notch3 notch homolog 3 0.518
dlb deltaB 0.466
cxcr4b chemokine (C-X-C motif), receptor 4b 0.322
shha sonic hedgehog a 0.281
itgb1b.2 integrin, beta 1b.2 0.279
fgfr2 fibroblast growth factor receptor 2 0.278
mmp2 matrix metalloproteinase 2 0.270
spry4 sprouty (Drosophila) homolog 4 0.266
boc brother of CDO 0.203
sox2 SRY-box containing gene 2 0.179
ntn1a netrin 1a 0.170
eya1 eyes absent homolog 1 0.157
wnt11r wingless-type MMTV integration site family, member 11, related 0.156
ascl1a achaete-scute complex-like 1a (Drosophila) 0.135
gli1 GLI-Kruppel family member 1 0.127
sox3 SRY-box containing gene 3 0.121
epha4a eph receptor A4a 0.116
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.114
tie2 endothelium-specific receptor tyrosine kinase 2 0.105
tnfsf10l tumor necrosis factor (ligand) superfamily, member 10 like 0.104
midn midnolin 0.102
rorb RAR-related orphan receptor B 0.101
sfrp1a secreted frizzled-related protein 1a 0.099
sulf1 sulfatase 1 0.098
jag1b jagged 1b 0.097
sox11a SRY-box containing gene 11a 0.096
slit3 slit (Drosophila) homolog 3 0.096
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.095
tbx2b T-box 2b 0.094
dtng dystrobrevin, gamma and dystrobrevin, gamma-like 0.092
zgc:153063 zgc:153063 0.091
tbx1 T-box 1 0.090
fgf10a fibroblast growth factor 10a 0.090
fzd7b frizzled homolog 7b 0.089
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.087
appa amyloid beta (A4) precursor protein a 0.083
dld deltaD 0.078
nrarpa notch-regulated ankyrin repeat protein a 0.076
ilk integrin linked kinase 0.075
gli2a GLI-Kruppel family member GLI2a 0.075
sall1a sal-like 1a (Drosophila) 0.073
bmp4 bone morphogenetic protein 4 0.070
pea3 ETS-domain transcription factor pea3 0.069
wnt8b wingless-type MMTV integration site family, member 8b 0.068
srf serum response factor 0.067
prox1 prospero-related homeobox gene 1 0.066
pax7a paired box gene 7a 0.064
alcama activated leukocyte cell adhesion molecule a 0.064
robo3 roundabout homolog 3 0.063
wnt10a wingless-type MMTV integration site family, member 10a 0.063
ubiad1 UbiA prenyltransferase domain containing 1 0.062
ptch2 patched 2 0.062
msxc muscle segment homeobox C 0.062
flt4 fms-related tyrosine kinase 4 0.061
zgc:171802 zgc:171802 0.060
pdlim1 PDZ and LIM domain 1 (elfin) 0.059
axin2 axin 2 (conductin, axil) 0.059
foxi3a forkhead box I3a 0.057
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.057
prdm5 PR domain containing 5 0.057
pou3f1 POU class 3 homeobox 1 0.056
dla deltaA 0.055
wnt1 wingless-type MMTV integration site family, member 1 0.052
itgb1b.1 integrin, beta 1b.1 0.051
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.051
fshb follicle stimulating hormone, beta polypeptide 0.050
prkci protein kinase C, iota 0.049
spns2 spinster homolog 2 (Drosophila) 0.048
irx2a iroquois homeobox protein 2, a 0.046
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.046
fbn2b fibrillin 2b 0.046
nf1a neurofibromin 1a 0.044
itgb1a integrin, beta 1a 0.043
sox11b SRY-box containing gene 11b 0.043
her6 hairy-related 6 0.042
ywhag1 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 0.042
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.042
plcg1 phospholipase C, gamma 1 0.041
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.041
notch1a notch homolog 1a 0.041
zgc:77123 zgc:77123 0.041
mtp microsomal triglyceride transfer protein 0.040
pak1 p21/Cdc42/Rac1-activated kinase 1 0.040
rtn1a reticulon 1a 0.040
birc2 baculoviral IAP repeat-containing 2 0.040
otpb orthopedia homolog b 0.038
col14a1 collagen, type XIV, alpha 1 0.038
utrn utrophin 0.038
pitx3 paired-like homeodomain transcription factor 3 0.038
nr2f1a nuclear receptor subfamily 2, group F, member 1a 0.037
mapk1 mitogen-activated protein kinase 1 0.036
cdh23 cadherin-like 23 0.036
hoxd4a homeo box D4a 0.035
myod1 myogenic differentiation 1 0.035
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Egfr Epidermal growth factor receptor 0.492
Ras85D Ras oncogene at 85D 0.230
InR Insulin-like receptor 0.115
tkv thickveins 0.063
shn schnurri 0.041
Ptp69D Protein tyrosine phosphatase 69D 0.041
LanA Laminin A 0.039
Mad Mothers against dpp 0.038
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.038
Abl Abl tyrosine kinase 0.036
foxo forkhead box, sub-group O 0.032
rut rutabaga 0.030
spi spitz 0.027
mys myospheroid 0.026
pan pangolin 0.025
Mical Molecule interacting with CasL 0.024
babo baboon 0.024
N Notch 0.024
wupA wings up A 0.024
pod1 CG4532 gene product from transcript CG4532-RF 0.024
Sema-1a CG18405 gene product from transcript CG18405-RD 0.024
CG42629 CG42629 gene product from transcript CG42629-RB 0.023
if inflated 0.022
tutl turtle 0.019
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.019
Mhc Myosin heavy chain 0.018
chb chromosome bows 0.018
sli slit 0.018
caz cabeza 0.017
Stat92E Signal-transducer and activator of transcription protein at 92E 0.017
dsh dishevelled 0.017
DAAM Dishevelled Associated Activator of Morphogenesis 0.016
put punt 0.015
G-oalpha47A G protein oalpha 47A 0.015
mol moladietz 0.015
CadN Cadherin-N 0.015
twi twist 0.015
trio CG18214 gene product from transcript CG18214-RA 0.014
raw CG12437 gene product from transcript CG12437-RB 0.014
sbb scribbler 0.014
shg shotgun 0.014
ci cubitus interruptus 0.014
CG13253 CG13253 gene product from transcript CG13253-RB 0.014
aop anterior open 0.014
CG7222 CG7222 gene product from transcript CG7222-RA 0.013
wb wing blister 0.013
kay kayak 0.013
cher cheerio 0.012
sgl sugarless 0.012
Nrg Neuroglian 0.012
Tbh Tyramine beta hydroxylase 0.012
myoglianin CG1838 gene product from transcript CG1838-RD 0.012
Tre1 trapped in endoderm-1 0.011
drk downstream of receptor kinase 0.011
dnc dunce 0.011
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.011
shot short stop 0.011
comm commissureless 0.011
kon kon-tiki 0.011
Trim9 CG31721 gene product from transcript CG31721-RB 0.011
Fas2 Fasciclin 2 0.010
nwk nervous wreck 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Notch2 Notch gene homolog 2 (Drosophila) 0.979
Nos3 nitric oxide synthase 3, endothelial cell 0.976
Col1a1 collagen, type I, alpha 1 0.966
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.948
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.934
Fbn1 fibrillin 1 0.915
Gli2 GLI-Kruppel family member GLI2 0.906
Lox lysyl oxidase 0.899
Tbx3 T-box 3 0.822
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.814
Egfr epidermal growth factor receptor 0.748
Notch1 Notch gene homolog 1 (Drosophila) 0.738
Eln elastin 0.714
Dll1 delta-like 1 (Drosophila) 0.713
Sox18 SRY-box containing gene 18 0.711
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.707
Fgfr1 fibroblast growth factor receptor 1 0.702
Trp53 transformation related protein 53 0.629
Kdr kinase insert domain protein receptor 0.627
Bcl2 B-cell leukemia/lymphoma 2 0.625
Sox10 SRY-box containing gene 10 0.617
Pten phosphatase and tensin homolog 0.603
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.586
Pkd1 polycystic kidney disease 1 homolog 0.581
Vegfa vascular endothelial growth factor A 0.560
Slit3 slit homolog 3 (Drosophila) 0.537
C1qc complement component 1, q subcomponent, C chain 0.523
Col3a1 collagen, type III, alpha 1 0.522
Vasp vasodilator-stimulated phosphoprotein 0.515
Fgfr2 fibroblast growth factor receptor 2 0.497
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.489
Itga3 integrin alpha 3 0.480
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.466
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.447
Robo1 roundabout homolog 1 (Drosophila) 0.445
Shh sonic hedgehog 0.444
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.443
Icam1 intercellular adhesion molecule 1 0.423
Flt4 FMS-like tyrosine kinase 4 0.417
Nckap1l NCK associated protein 1 like 0.416
Col5a2 collagen, type V, alpha 2 0.412
Ctnnb1 catenin (cadherin associated protein), beta 1 0.401
Msn moesin 0.395
Tagln transgelin 0.380
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.374
Sfrp1 secreted frizzled-related protein 1 0.374
Sox7 SRY-box containing gene 7 0.352
Adra2b adrenergic receptor, alpha 2b 0.349
Scn5a sodium channel, voltage-gated, type V, alpha 0.346
Fzd1 frizzled homolog 1 (Drosophila) 0.342
Amhr2 anti-Mullerian hormone type 2 receptor 0.338
Loxl1 lysyl oxidase-like 1 0.333
Thbs1 thrombospondin 1 0.333
Itgam integrin alpha M 0.326
Col6a2 collagen, type VI, alpha 2 0.319
Lrp1 low density lipoprotein receptor-related protein 1 0.305
Pthlh parathyroid hormone-like peptide 0.302
Cdh5 cadherin 5 0.302
Kl klotho 0.302
Inpp5d inositol polyphosphate-5-phosphatase D 0.302
Esr1 estrogen receptor 1 (alpha) 0.302
Flt1 FMS-like tyrosine kinase 1 0.294
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.294
Tgfb1i1 transforming growth factor beta 1 induced transcript 1 0.279
Pdgfb platelet derived growth factor, B polypeptide 0.278
Fgf5 fibroblast growth factor 5 0.274
Tgfa transforming growth factor alpha 0.273
Cldn5 claudin 5 0.273
Aebp1 AE binding protein 1 0.265
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.265
Fgf8 fibroblast growth factor 8 0.264
C1qa complement component 1, q subcomponent, alpha polypeptide 0.263
Stat5b signal transducer and activator of transcription 5B 0.261
Ccbp2 chemokine binding protein 2 0.253
Fstl1 follistatin-like 1 0.253
Lama5 laminin, alpha 5 0.253
C5ar1 complement component 5a receptor 1 0.248
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.244
Cdh6 cadherin 6 0.243
Esam endothelial cell-specific adhesion molecule 0.242
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.242
Col13a1 collagen, type XIII, alpha 1 0.242
Efnb2 ephrin B2 0.241
Pcolce procollagen C-endopeptidase enhancer protein 0.240
Prl8a2 prolactin family 8, subfamily a, member 2 0.236
Meox2 mesenchyme homeobox 2 0.236
Fgfr3 fibroblast growth factor receptor 3 0.234
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.231
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.228
Gpr3 G-protein coupled receptor 3 0.222
Irf9 interferon regulatory factor 9 0.221
Col4a1 collagen, type IV, alpha 1 0.221
Wnt3a wingless-related MMTV integration site 3A 0.220
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.219
Tnc tenascin C 0.218
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.218
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.216
Myl9 myosin, light polypeptide 9, regulatory 0.215
Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.214
Acan aggrecan 0.214
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism