The network for 'cellular metal ion homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular metal ion homeostasis

Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.

Homo sapiens
Name Description Probability Func Analog Organism
SMN1 survival of motor neuron 1, telomeric 0.994
GRB2 growth factor receptor-bound protein 2 0.985
CCR5 chemokine (C-C motif) receptor 5 0.973
FGFR2 fibroblast growth factor receptor 2 0.958
FYN FYN oncogene related to SRC, FGR, YES 0.936
NCF1 neutrophil cytosolic factor 1 0.932
BTK Bruton agammaglobulinemia tyrosine kinase 0.931
GSTM1 glutathione S-transferase mu 1 0.920
C1QA complement component 1, q subcomponent, A chain 0.911
CXCL9 chemokine (C-X-C motif) ligand 9 0.888
SH3KBP1 SH3-domain kinase binding protein 1 0.875
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.856
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.846
LAT linker for activation of T cells 0.842
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.825
EGFR epidermal growth factor receptor 0.810
GSTM2 glutathione S-transferase mu 2 (muscle) 0.774
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.767
ACTN2 actinin, alpha 2 0.755
ARRB1 arrestin, beta 1 0.754
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.749
MPDZ multiple PDZ domain protein 0.747
PRKCA protein kinase C, alpha 0.742
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.740
NCF2 neutrophil cytosolic factor 2 0.732
TTN titin 0.727
CCL22 chemokine (C-C motif) ligand 22 0.710
SYK spleen tyrosine kinase 0.698
CCL4 chemokine (C-C motif) ligand 4 0.695
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.688
CCL5 chemokine (C-C motif) ligand 5 0.686
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.685
CXCL10 chemokine (C-X-C motif) ligand 10 0.665
FGFR1 fibroblast growth factor receptor 1 0.649
CCL2 chemokine (C-C motif) ligand 2 0.635
CCL19 chemokine (C-C motif) ligand 19 0.628
CAV1 caveolin 1, caveolae protein, 22kDa 0.619
CCR1 chemokine (C-C motif) receptor 1 0.618
PSEN2 presenilin 2 (Alzheimer disease 4) 0.617
VEGFA vascular endothelial growth factor A 0.603
IL8 interleukin 8 0.594
PRKCG protein kinase C, gamma 0.592
SOCS3 suppressor of cytokine signaling 3 0.590
TNF tumor necrosis factor 0.579
CXCL2 chemokine (C-X-C motif) ligand 2 0.558
PDIA3 protein disulfide isomerase family A, member 3 0.549
CXCL3 chemokine (C-X-C motif) ligand 3 0.541
CCL7 chemokine (C-C motif) ligand 7 0.541
ICAM1 intercellular adhesion molecule 1 0.539
PRKCB protein kinase C, beta 0.533
BCL2L1 BCL2-like 1 0.526
IL10 interleukin 10 0.519
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.511
IFNG interferon, gamma 0.491
CALB1 calbindin 1, 28kDa 0.489
NRP1 neuropilin 1 0.484
CPD carboxypeptidase D 0.479
IL2RB interleukin 2 receptor, beta 0.476
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.476
CCR7 chemokine (C-C motif) receptor 7 0.469
EPOR erythropoietin receptor 0.469
KIAA1683 KIAA1683 0.468
PRKCQ protein kinase C, theta 0.467
CCL8 chemokine (C-C motif) ligand 8 0.466
NCF4 neutrophil cytosolic factor 4, 40kDa 0.448
MAPT microtubule-associated protein tau 0.440
MET met proto-oncogene (hepatocyte growth factor receptor) 0.434
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.428
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.428
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.426
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.420
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.417
CABP1 calcium binding protein 1 0.413
SLC4A1 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) 0.406
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.400
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.394
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.382
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.382
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.382
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.375
DRD2 dopamine receptor D2 0.374
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.373
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.366
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.354
C1QB complement component 1, q subcomponent, B chain 0.351
CXCR5 chemokine (C-X-C motif) receptor 5 0.345
CXCL11 chemokine (C-X-C motif) ligand 11 0.341
GSTM4 glutathione S-transferase mu 4 0.340
MAX MYC associated factor X 0.340
HTR4 5-hydroxytryptamine (serotonin) receptor 4 0.339
CCL20 chemokine (C-C motif) ligand 20 0.337
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.337
ACHE acetylcholinesterase 0.333
VAV1 vav 1 guanine nucleotide exchange factor 0.332
CALCA calcitonin-related polypeptide alpha 0.329
HP haptoglobin 0.327
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.326
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.323
SIGLEC7 sialic acid binding Ig-like lectin 7 0.322
CCKBR cholecystokinin B receptor 0.321
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
eat-6 Protein EAT-6 0.073
eat-4 Protein EAT-4 0.045
pkg-1 Protein PKG-1 0.030
zyx-1 Protein ZYX-1 0.025
unc-27 Protein UNC-27 0.019
rig-6 Protein RIG-6 0.018
pde-4 Protein PDE-4 0.018
dpy-23 Protein DPY-23 0.017
vha-14 Protein VHA-14 0.017
CELE_B0513.5 Protein B0513.5 0.015
miz-1 Protein MIZ-1 0.014
egl-8 Protein EGL-8 0.013
sur-7 Protein SUR-7 0.013
T12D8.9 Protein T12D8.9 0.012
ogdh-1 Protein OGDH-1 0.012
C54E4.2 Protein C54E4.2 0.012
unc-15 Protein UNC-15 0.012
obr-3 Protein OBR-3 0.011
plc-1 Protein PLC-1 0.011
daf-12 Protein DAF-12 0.011
F01G4.6 Protein F01G4.6 0.011
act-4 Protein ACT-4 0.011
daf-4 Protein DAF-4 0.010
CELE_Y64G10A.6 Protein Y64G10A.6 0.010
nhr-170 Protein NHR-170 0.010
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Danio rerio
Name Description Probability Func Analog Organism
spry4 sprouty (Drosophila) homolog 4 0.261
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.189
dusp6 dual specificity phosphatase 6 0.143
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.132
wnt10a wingless-type MMTV integration site family, member 10a 0.120
chat choline acetyltransferase 0.095
cacnb4a calcium channel, voltage-dependent, beta 4a subunit 0.075
tnnt2a troponin T2a, cardiac 0.067
wnt10b wingless-type MMTV integration site family, member 10b 0.060
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.060
mc4r melanocortin 4 receptor 0.059
opn4l opsin 4, like 0.053
stac3 SH3 and cysteine rich domain 3 0.052
tfr1a transferrin receptor 1a 0.050
valopa vertebrate ancient long opsin a 0.047
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.046
wnt11r wingless-type MMTV integration site family, member 11, related 0.045
si:ch73-60e21.1 si:ch73-60e21.1 0.044
cx39.9 connexin 39.9 0.042
tnni2a.4 troponin I, skeletal, fast 2a.4 0.042
ppargc1al peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like 0.041
chrm2a cholinergic receptor, muscarinic 2a 0.041
dbh dopamine beta hydroxylase 0.039
opn1sw2 opsin 1 (cone pigments), short-wave-sensitive 2 0.039
cmlc1 cardiac myosin light chain-1 0.037
atp1b2b ATPase, Na+/K+ transporting, beta 2b polypeptide 0.037
opn4a opsin 4a (melanopsin) 0.035
tnnt3a troponin T3a, skeletal, fast 0.035
wnt1 wingless-type MMTV integration site family, member 1 0.034
hbaa1 hemoglobin alpha adult-1 0.033
bmp7a bone morphogenetic protein 7a 0.032
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.031
tpma alpha-tropomyosin 0.031
pvalb2 parvalbumin 2 0.031
appa amyloid beta (A4) precursor protein a 0.030
epas1b endothelial PAS domain protein 1b 0.030
lama2 laminin, alpha 2 0.030
snai1a snail homolog 1a (Drosophila) 0.030
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.029
ttna titin a 0.029
esrra estrogen-related receptor alpha 0.029
fbp1b fructose-1,6-bisphosphatase 1b 0.029
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.029
mmp9 matrix metalloproteinase 9 0.029
actn3a actinin alpha 3a 0.028
tnnc1a troponin C type 1a (slow) 0.028
col11a2 collagen type XI alpha-2 0.028
ckma creatine kinase, muscle a 0.028
atp6v1al ATPase, H+ transporting, lysosomal V1 subunit A, like 0.027
alcamb activated leukocyte cell adhesion molecule b 0.027
bcl2 B-cell leukemia/lymphoma 2 0.027
csf3r colony stimulating factor 3 receptor (granulocyte) 0.026
opn1mw1 opsin 1 (cone pigments), medium-wave-sensitive, 1 0.026
ldb3b LIM domain binding 3b 0.026
si:dkey-273o13.1 si:dkey-273o13.1 0.025
ptger4a prostaglandin E receptor 4 (subtype EP4) a 0.025
myd88 myeloid differentiation primary response gene (88) 0.025
mc1r melanocortin 1 receptor 0.025
hspb12 heat shock protein, alpha-crystallin-related, b12 0.024
rbm24a RNA binding motif protein 24a 0.022
opn1sw1 opsin 1 (cone pigments), short-wave-sensitive 1 0.022
hbbe1.1 hemoglobin beta embryonic-1.1 0.022
aco1 aconitase 1, soluble 0.022
gja3 gap junction protein, alpha 3 0.022
valopb vertebrate ancient long opsin b 0.021
glra1 glycine receptor, alpha 1 0.021
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.021
slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.021
bmp4 bone morphogenetic protein 4 0.020
itgb1a integrin, beta 1a 0.020
tnnt3b troponin T3b, skeletal, fast 0.020
mchr1a melanin-concentrating hormone receptor 1a 0.020
tfa transferrin-a 0.019
lin7a lin-7 homolog A (C. elegans) 0.019
gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b 0.019
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.019
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.019
smyhc1l slow myosin heavy chain 1, like 0.019
grin1a glutamate receptor, ionotropic, N-methyl D-aspartate 1a 0.018
pvalb4 parvalbumin 4 0.018
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.018
nbl1 neuroblastoma, suppression of tumorigenicity 1 0.017
gad2 glutamate decarboxylase 2 0.017
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.017
mmp14a matrix metalloproteinase 14a (membrane-inserted) 0.017
zgc:193613 zgc:193613 0.017
LOC566708 FL cytokine receptor-like 0.017
mef2ca myocyte enhancer factor 2ca 0.017
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.017
cx36.7 connexin 36.7 0.017
tbx5a T-box 5a 0.017
pi4kb phosphatidylinositol 4-kinase, catalytic, beta 0.017
ireb2 iron-responsive element binding protein 2 0.017
il6r interleukin 6 receptor 0.017
wls wntless homolog (Drosophila) 0.016
hcst hematopoietic cell signal transducer 0.016
inhbaa inhibin, beta Aa 0.016
nr2f6a nuclear receptor subfamily 2, group F, member 6a 0.016
crabp2b cellular retinoic acid binding protein 2, b 0.016
or107-1 odorant receptor, family D, subfamily 107, member 1 0.016
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
inaD inactivation no afterpotential D 0.928
ninaE neither inactivation nor afterpotential E 0.820
trpl trp-like 0.557
norpA no receptor potential A 0.434
para paralytic 0.412
G-oalpha47A G protein oalpha 47A 0.391
Pten CG5671 gene product from transcript CG5671-RB 0.338
trp transient receptor potential 0.278
Pvr PDGF- and VEGF-receptor related 0.276
Cat Catalase 0.242
stnB stoned B 0.208
CG4858 CG4858 gene product from transcript CG4858-RA 0.204
Ace Acetylcholine esterase 0.175
e ebony 0.162
Wnt5 Wnt oncogene analog 5 0.154
CG4468 CG4468 gene product from transcript CG4468-RA 0.153
Rh5 Rhodopsin 5 0.150
Act57B Actin 57B 0.149
Rh6 Rhodopsin 6 0.138
CG7191 CG7191 gene product from transcript CG7191-RA 0.130
Arr1 Arrestin 1 0.122
Arr2 Arrestin 2 0.117
5-HT1A Serotonin receptor 1A 0.112
S6k RPS6-p70-protein kinase 0.103
CG8090 CG8090 gene product from transcript CG8090-RB 0.097
CG9894 CG9894 gene product from transcript CG9894-RB 0.091
Aats-glupro Glutamyl-prolyl-tRNA synthetase 0.091
CG12004 CG12004 gene product from transcript CG12004-RC 0.087
Rh3 Rhodopsin 3 0.084
l(3)76BDm lethal (3) 76BDm 0.084
Fer2LCH Ferritin 2 light chain homologue 0.078
Vha26 Vacuolar H[+]-ATPase 26kD E subunit 0.078
elav embryonic lethal abnormal vision 0.077
neuroligin CG13772 gene product from transcript CG13772-RA 0.072
Mmp2 Matrix metalloproteinase 2 0.069
Timp Tissue inhibitor of metalloproteases 0.068
Nrx-1 Neurexin 1 0.068
Fer1HCH Ferritin 1 heavy chain homologue 0.067
CG14864 CG14864 gene product from transcript CG14864-RB 0.065
Zasp66 Z band alternatively spliced PDZ-motif protein 66 0.064
pHCl CG33989 gene product from transcript CG33989-RD 0.063
rut rutabaga 0.063
if inflated 0.062
Vha55 Vacuolar H[+]-ATPase 55kD B subunit 0.062
CG8709 CG8709 gene product from transcript CG8709-RK 0.061
desat1 CG5887 gene product from transcript CG5887-RA 0.061
Syt1 Synaptotagmin 1 0.060
CG32635 CG32635 gene product from transcript CG32635-RA 0.059
Mpcp Mitochondrial phosphate carrier protein 0.059
VhaPPA1-1 CG7007 gene product from transcript CG7007-RA 0.058
ct cut 0.058
MTF-1 Metal response element-binding Transcription Factor-1 0.057
wtrw CG31284 gene product from transcript CG31284-RB 0.055
ex expanded 0.055
Elongin-C Elongin C 0.055
rok Rho-kinase 0.054
cad caudal 0.054
ric8a CG15797 gene product from transcript CG15797-RA 0.054
GRHR Gonadotropin-releasing hormone receptor 0.054
dco discs overgrown 0.053
Vha68-2 CG3762 gene product from transcript CG3762-RA 0.052
up upheld 0.051
ninaA neither inactivation nor afterpotential A 0.050
LpR2 CG31092 gene product from transcript CG31092-RD 0.050
dm diminutive 0.050
amon amontillado 0.048
Dms Dromyosuppressin 0.047
caz cabeza 0.047
t tan 0.047
Plc21C Phospholipase C at 21C 0.046
nwk nervous wreck 0.046
Pcaf CG4107 gene product from transcript CG4107-RA 0.045
Scsalpha Succinyl coenzyme A synthetase alpha subunit 0.044
per period 0.044
VGlut Vesicular glutamate transporter 0.044
katanin-60 katanin 60 0.043
Hcf Host cell factor 0.043
ZnT63C CG17723 gene product from transcript CG17723-RD 0.043
CG7686 CG7686 gene product from transcript CG7686-RA 0.043
Npc1a Niemann-Pick type C-1a 0.040
Rdl Resistant to dieldrin 0.040
5-HT7 Serotonin receptor 7 0.040
tipE temperature-induced paralytic E 0.039
Tm2 Tropomyosin 2 0.038
VhaSFD Vacuolar H[+]-ATPase SFD subunit 0.037
sls sallimus 0.037
Gp150 CG5820 gene product from transcript CG5820-RA 0.036
Cam Calmodulin 0.036
Glut1 Glucose transporter 1 0.036
ewg erect wing 0.035
Tom34 Translocase of outer membrane 34 0.035
boss bride of sevenless 0.035
CG7188 CG7188 gene product from transcript CG7188-RA 0.035
Gad1 Glutamic acid decarboxylase 1 0.035
HspB8 CG14207 gene product from transcript CG14207-RB 0.034
CG12264 CG12264 gene product from transcript CG12264-RA 0.034
wit wishful thinking 0.034
Stim Stromal interaction molecule 0.033
Mpk2 CG5475 gene product from transcript CG5475-RB 0.033
pgant3 polypeptide GalNAc transferase 3 0.033
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ldb3 LIM domain binding 3 0.975
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.964
Prnp prion protein 0.929
Lepr leptin receptor 0.919
Ank1 ankyrin 1, erythroid 0.919
Pten phosphatase and tensin homolog 0.912
Thrb thyroid hormone receptor beta 0.901
Hbb-b1 hemoglobin, beta adult major chain 0.841
Drd2 dopamine receptor D2 0.841
Nos3 nitric oxide synthase 3, endothelial cell 0.817
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.811
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.810
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.808
Hrc histidine rich calcium binding protein 0.799
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.789
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.780
Kit kit oncogene 0.773
Insr insulin receptor 0.768
Fyn Fyn proto-oncogene 0.756
Tfrc transferrin receptor 0.753
Ccr1 chemokine (C-C motif) receptor 1 0.752
Il6 interleukin 6 0.741
Ccl2 chemokine (C-C motif) ligand 2 0.731
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.728
Ikzf1 IKAROS family zinc finger 1 0.721
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.719
Ren1 renin 1 structural 0.714
Myl3 myosin, light polypeptide 3 0.709
Ttn titin 0.699
Ntf3 neurotrophin 3 0.684
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.675
Actn2 actinin alpha 2 0.670
Chrm3 cholinergic receptor, muscarinic 3, cardiac 0.668
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.656
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.646
Vamp2 vesicle-associated membrane protein 2 0.637
Dlg4 discs, large homolog 4 (Drosophila) 0.625
S1pr2 sphingosine-1-phosphate receptor 2 0.624
App amyloid beta (A4) precursor protein 0.622
Sstr4 somatostatin receptor 4 0.619
Ptgs2 prostaglandin-endoperoxide synthase 2 0.614
Vegfa vascular endothelial growth factor A 0.605
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.599
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.599
Cd40 CD40 antigen 0.595
Ccl3 chemokine (C-C motif) ligand 3 0.583
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.582
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.575
Adrb1 adrenergic receptor, beta 1 0.571
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.561
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.536
Ar androgen receptor 0.533
Prkcc protein kinase C, gamma 0.533
Ccr2 chemokine (C-C motif) receptor 2 0.526
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.525
Cx3cr1 chemokine (C-X3-C) receptor 1 0.522
Pparg peroxisome proliferator activated receptor gamma 0.518
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.517
Otp orthopedia homolog (Drosophila) 0.517
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.512
Gdf3 growth differentiation factor 3 0.506
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.494
Esr2 estrogen receptor 2 (beta) 0.492
Ednrb endothelin receptor type B 0.492
Casq2 calsequestrin 2 0.488
Dok1 docking protein 1 0.483
Ptprc protein tyrosine phosphatase, receptor type, C 0.478
Ptk2 PTK2 protein tyrosine kinase 2 0.470
Clcn1 chloride channel 1 0.467
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.466
Kitl kit ligand 0.462
Hrh1 histamine receptor H1 0.461
Clec4d C-type lectin domain family 4, member d 0.459
Cd22 CD22 antigen 0.457
Cd44 CD44 antigen 0.456
Mb myoglobin 0.456
Vdr vitamin D receptor 0.455
Rgs9 regulator of G-protein signaling 9 0.454
Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 0.454
Gal galanin 0.452
Lep leptin 0.451
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.446
Mitf microphthalmia-associated transcription factor 0.440
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.434
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.429
Ccr6 chemokine (C-C motif) receptor 6 0.428
Steap3 STEAP family member 3 0.422
S100a10 S100 calcium binding protein A10 (calpactin) 0.421
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.418
Grb10 growth factor receptor bound protein 10 0.413
Gpr132 G protein-coupled receptor 132 0.407
Smyd1 SET and MYND domain containing 1 0.407
Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 0.405
Clstn1 calsyntenin 1 0.403
Avp arginine vasopressin 0.398
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.395
Lta lymphotoxin A 0.393
Arpc4 actin related protein 2/3 complex, subunit 4 0.392
Nos1 nitric oxide synthase 1, neuronal 0.384
Ryr3 ryanodine receptor 3 0.382
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Itgam integrin, alpha M 0.724
Kcnmb1 potassium large conductance calcium-activated channel, subfamily M, beta member 1 0.651
Dlg4 discs, large homolog 4 (Drosophila) 0.530
Tnni1 troponin I type 1 (skeletal, slow) 0.528
Ppyr1 pancreatic polypeptide receptor 1 0.512
Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 0.491
Iapp islet amyloid polypeptide 0.484
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.478
Il4 interleukin 4 0.475
Agtr1a angiotensin II receptor, type 1a 0.472
Trhr2 thyrotropin releasing hormone receptor 2 0.460
Fgf2 fibroblast growth factor 2 0.447
Mamdc4 MAM domain containing 4 0.435
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.428
Csf1 colony stimulating factor 1 (macrophage) 0.394
Nlgn2 neuroligin 2 0.384
Hr hairless 0.365
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.361
Cmklr1 chemokine-like receptor 1 0.360
Lim2 lens intrinsic membrane protein 2 0.350
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.344
Chrna3 cholinergic receptor, nicotinic, alpha 3 0.341
Irs1 insulin receptor substrate 1 0.340
Glp1r glucagon-like peptide 1 receptor 0.336
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.324
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.323
Cd53 Cd53 molecule 0.323
Cxcr4 chemokine (C-X-C motif) receptor 4 0.320
Adam7 ADAM metallopeptidase domain 7 0.315
Fam38b family with sequence similarity 38, member B 0.312
Jak1 Janus kinase 1 0.310
Grid2 glutamate receptor, ionotropic, delta 2 0.306
Vom2r27 vomeronasal 2 receptor, 27 0.304
Cd8a CD8a molecule 0.303
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.302
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.294
Sell selectin L 0.282
Mrgprf MAS-related GPR, member F 0.280
Fxyd4 FXYD domain-containing ion transport regulator 4 0.277
Igfals insulin-like growth factor binding protein, acid labile subunit 0.275
Npy2r neuropeptide Y receptor Y2 0.274
Mapk3 mitogen activated protein kinase 3 0.269
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.264
Mmp10 matrix metallopeptidase 10 0.262
P2rx1 purinergic receptor P2X, ligand-gated ion channel, 1 0.260
LOC690358 similar to PR domain containing 11 0.260
Il2rb interleukin 2 receptor, beta 0.259
Pgf placental growth factor 0.259
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.255
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.253
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.248
Phkg1 phosphorylase kinase, gamma 1 0.247
Kl Klotho 0.245
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.245
Ccl2 chemokine (C-C motif) ligand 2 0.245
Igsf6 immunoglobulin superfamily, member 6 0.244
Dchs1 dachsous 1 (Drosophila) 0.243
Cybb cytochrome b-245, beta polypeptide 0.240
Cxcr5 chemokine (C-X-C motif) receptor 5 0.234
Sdc3 syndecan 3 0.231
Gria1 glutamate receptor, ionotropic, AMPA 1 0.228
Kcng2 potassium voltage-gated channel, subfamily G, member 2 0.226
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.225
Crhr1 corticotropin releasing hormone receptor 1 0.224
Grm6 glutamate receptor, metabotropic 6 0.222
Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 0.222
Kcnk9 potassium channel, subfamily K, member 9 0.221
Nos3 nitric oxide synthase 3, endothelial cell 0.220
C3ar1 complement component 3a receptor 1 0.218
Scn5a sodium channel, voltage-gated, type V, alpha subunit 0.216
Syn2 synapsin II 0.216
Casp1 caspase 1 0.215
Il9r interleukin 9 receptor 0.213
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.213
F13a1 coagulation factor XIII, A1 polypeptide 0.212
S1pr2 sphingosine-1-phosphate receptor 2 0.207
Gja6 gap junction protein, alpha 6 0.207
Prlh prolactin releasing hormone 0.207
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.205
Akr1c18 aldo-keto reductase family 1, member C18 0.204
Dock8 dedicator of cytokinesis 8 0.204
Drd1a dopamine receptor D1A 0.201
Cartpt CART prepropeptide 0.201
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.201
Serpina11 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 0.199
Ccr3 chemokine (C-C motif) receptor 3 0.199
Il1b interleukin 1 beta 0.198
Il2rg interleukin 2 receptor, gamma 0.197
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.195
Cxcl10 chemokine (C-X-C motif) ligand 10 0.193
Cd14 CD14 molecule 0.193
Syt6 synaptotagmin VI 0.191
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.189
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.188
Slc22a25 solute carrier family 22, member 25 0.187
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.187
Nos1 nitric oxide synthase 1, neuronal 0.186
Apcs amyloid P component, serum 0.184
Kiss1r KISS1 receptor 0.183
Ntf4 neurotrophin 4 0.181
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ARN1 Arn1p 0.719
AFT1 Aft1p 0.664
ENA5 Ena5p 0.656
TRK1 Trk1p 0.573
NHX1 Nhx1p 0.549
FET5 Fet5p 0.519
PPZ1 Ppz1p 0.492
PMR1 Pmr1p 0.465
TIS11 Tis11p 0.433
IZH2 Izh2p 0.410
FRE6 Fre6p 0.389
AKR1 Akr1p 0.357
VPH1 Vph1p 0.353
AVO1 Avo1p 0.346
YFH1 Yfh1p 0.318
MOB1 Mob1p 0.313
TOK1 Tok1p 0.308
IZH4 Izh4p 0.306
YBR235W hypothetical protein 0.295
TOR2 Tor2p 0.294
GRX4 Grx4p 0.284
TOR1 Tor1p 0.253
ZRG17 Zrg17p 0.253
FTR1 Ftr1p 0.245
RFT1 Rft1p 0.241
GDB1 Gdb1p 0.240
FTH1 Fth1p 0.237
PHO86 Pho86p 0.235
CCC2 Ccc2p 0.231
ROX1 Rox1p 0.228
CRZ1 Crz1p 0.221
VID24 Vid24p 0.213
VMA5 Vma5p 0.211
AUR1 Aur1p 0.207
SMF3 Smf3p 0.207
RIM13 Rim13p 0.202
PPQ1 Ppq1p 0.200
ERG2 Erg2p 0.192
GPH1 Gph1p 0.188
TRA1 Tra1p 0.188
SKS1 Sks1p 0.187
YMR221C hypothetical protein 0.186
MIG2 Mig2p 0.183
SMF1 Smf1p 0.183
HSP42 Hsp42p 0.166
ENA2 Ena2p 0.165
PET8 Pet8p 0.162
LST4 Lst4p 0.161
VMA1 Vma1p 0.161
VMA3 Vma3p 0.156
RTS1 Rts1p 0.154
TAT1 Tat1p 0.154
MIG3 Mig3p 0.152
ISU1 Isu1p 0.150
OLE1 Ole1p 0.149
VMA16 Vma16p 0.148
TRS23 Trs23p 0.145
TRK2 Trk2p 0.143
YPC1 Ypc1p 0.142
TSC11 Tsc11p 0.141
CFD1 Cfd1p 0.141
DRE2 Dre2p 0.135
ALG8 Alg8p 0.135
TPS2 Tps2p 0.129
ATG27 Atg27p 0.126
ATG32 Atg32p 0.125
ISA1 Isa1p 0.124
RTG3 Rtg3p 0.124
ACO1 Aco1p 0.123
PEX25 Pex25p 0.123
SDS24 Sds24p 0.119
YAP5 Yap5p 0.116
ARN2 Arn2p 0.116
MGA2 Mga2p 0.116
MPM1 Mpm1p 0.114
COS6 Cos6p 0.114
SOG2 Sog2p 0.112
TPK1 Tpk1p 0.112
DBF2 Dbf2p 0.112
SSQ1 Ssq1p 0.112
COX4 Cox4p 0.112
STE11 Ste11p 0.112
SDH2 Sdh2p 0.111
FRE1 Fre1p 0.111
IPT1 Ipt1p 0.111
GCN1 Gcn1p 0.111
HAL9 Hal9p 0.110
GEF1 Gef1p 0.109
JAC1 Jac1p 0.107
AGP2 Agp2p 0.107
MDJ1 Mdj1p 0.106
UBP9 Ubp9p 0.104
ALD6 Ald6p 0.103
FIT2 Fit2p 0.102
ROD1 Rod1p 0.102
SIT1 Sit1p 0.101
YPK1 Ypk1p 0.101
STE14 Ste14p 0.099
ARR1 Arr1p 0.098
VHS2 Vhs2p 0.098