The network for 'negative regulation of phagocytosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of phagocytosis

Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.

Homo sapiens
Name Description Probability Func Analog Organism
C1QA complement component 1, q subcomponent, A chain 0.999
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.949
C1QC complement component 1, q subcomponent, C chain 0.896
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.766
TFF1 trefoil factor 1 0.730
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.706
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.682
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.646
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.635
ENG endoglin 0.524
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.514
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.501
HIPK2 homeodomain interacting protein kinase 2 0.473
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.416
C1QB complement component 1, q subcomponent, B chain 0.414
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.407
SYK spleen tyrosine kinase 0.391
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.357
PILRA paired immunoglobin-like type 2 receptor alpha 0.347
HK3 hexokinase 3 (white cell) 0.286
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.267
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.259
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.224
HIPK3 homeodomain interacting protein kinase 3 0.223
PXN paxillin 0.200
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.194
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.182
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.163
RIN1 Ras and Rab interactor 1 0.159
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.158
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.151
TGFBR1 transforming growth factor, beta receptor 1 0.148
SPRR2A small proline-rich protein 2A 0.145
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.135
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.134
MARCO macrophage receptor with collagenous structure 0.129
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.121
BCAR1 breast cancer anti-estrogen resistance 1 0.119
WDR83 WD repeat domain 83 0.119
CD33 CD33 molecule 0.111
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.108
MAVS mitochondrial antiviral signaling protein 0.103
UBASH3B ubiquitin associated and SH3 domain containing B 0.099
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.096
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.092
MYH9 myosin, heavy chain 9, non-muscle 0.087
WASF1 WAS protein family, member 1 0.086
MUC1 mucin 1, cell surface associated 0.077
PTAFR platelet-activating factor receptor 0.074
SOS1 son of sevenless homolog 1 (Drosophila) 0.074
MSH4 mutS homolog 4 (E. coli) 0.072
ZYX zyxin 0.070
CD300C CD300c molecule 0.069
FSTL1 follistatin-like 1 0.068
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.065
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.062
MSR1 macrophage scavenger receptor 1 0.060
ABI2 abl-interactor 2 0.058
STAB1 stabilin 1 0.058
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.056
FYN FYN oncogene related to SRC, FGR, YES 0.056
MPO myeloperoxidase 0.054
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.053
DYNLL1 dynein, light chain, LC8-type 1 0.053
PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) 0.052
SMAD2 SMAD family member 2 0.051
CYTH4 cytohesin 4 0.050
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.050
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.048
EPOR erythropoietin receptor 0.048
TREM2 triggering receptor expressed on myeloid cells 2 0.045
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.045
ZFYVE9 zinc finger, FYVE domain containing 9 0.045
SMAD3 SMAD family member 3 0.044
ADAM19 ADAM metallopeptidase domain 19 0.044
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.043
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.043
FLNA filamin A, alpha 0.042
CTSG cathepsin G 0.040
SIGLEC5 sialic acid binding Ig-like lectin 5 0.040
SIGLEC10 sialic acid binding Ig-like lectin 10 0.040
CREBBP CREB binding protein 0.039
CAMP cathelicidin antimicrobial peptide 0.039
TGFB3 transforming growth factor, beta 3 0.039
SORBS3 sorbin and SH3 domain containing 3 0.039
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 0.038
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.038
FPR1 formyl peptide receptor 1 0.038
GOLM1 golgi membrane protein 1 0.037
CLEC4G C-type lectin domain family 4, member G 0.037
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.036
THBS1 thrombospondin 1 0.036
EGFR epidermal growth factor receptor 0.036
SPI1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.035
CFP complement factor properdin 0.035
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.034
SND1 staphylococcal nuclease and tudor domain containing 1 0.034
C5AR1 complement component 5a receptor 1 0.033
APOBR apolipoprotein B receptor 0.033
MSH5 mutS homolog 5 (E. coli) 0.032
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Myl9 myosin, light polypeptide 9, regulatory 0.957
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.954
Dok1 docking protein 1 0.952
Inpp5d inositol polyphosphate-5-phosphatase D 0.940
Ptma prothymosin alpha 0.879
Tagln transgelin 0.799
Ric8 resistance to inhibitors of cholinesterase 8 homolog (C. elegans) 0.744
Cnn2 calponin 2 0.713
Acta2 actin, alpha 2, smooth muscle, aorta 0.691
Rps3 ribosomal protein S3 0.592
Apoe apolipoprotein E 0.573
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.547
Dok2 docking protein 2 0.537
Vasp vasodilator-stimulated phosphoprotein 0.512
Rhog ras homolog gene family, member G 0.499
Csf1r colony stimulating factor 1 receptor 0.498
Elane elastase, neutrophil expressed 0.451
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.444
Rps2 ribosomal protein S2 0.401
Rplp0 ribosomal protein, large, P0 0.396
Eef1a1 eukaryotic translation elongation factor 1 alpha 1 0.391
Csf1 colony stimulating factor 1 (macrophage) 0.385
Cebpe CCAAT/enhancer binding protein (C/EBP), epsilon 0.366
Dok3 docking protein 3 0.347
Tbxas1 thromboxane A synthase 1, platelet 0.322
Tyrobp TYRO protein tyrosine kinase binding protein 0.321
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.320
Cnn1 calponin 1 0.315
Trp53 transformation related protein 53 0.302
Unc93b1 unc-93 homolog B1 (C. elegans) 0.301
Ilk integrin linked kinase 0.244
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.238
Lyz2 lysozyme 2 0.231
Smtn smoothelin 0.230
Myo1c myosin IC 0.229
Braf Braf transforming gene 0.212
Selp selectin, platelet 0.208
Ncf1 neutrophil cytosolic factor 1 0.199
Rpl6 ribosomal protein L6 0.199
Crtap cartilage associated protein 0.193
Hck hemopoietic cell kinase 0.192
Hmgb1 high mobility group box 1 0.183
Csrp1 cysteine and glycine-rich protein 1 0.178
Crip1 cysteine-rich protein 1 (intestinal) 0.176
Tgfb1i1 transforming growth factor beta 1 induced transcript 1 0.171
Actn1 actinin, alpha 1 0.167
Flna filamin, alpha 0.166
Sipa1 signal-induced proliferation associated gene 1 0.165
Clec4a2 C-type lectin domain family 4, member a2 0.163
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.158
Mylk myosin, light polypeptide kinase 0.155
Stat3 signal transducer and activator of transcription 3 0.154
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.152
Stmn1 stathmin 1 0.149
Tlr4 toll-like receptor 4 0.149
Myh9 myosin, heavy polypeptide 9, non-muscle 0.146
Cotl1 coactosin-like 1 (Dictyostelium) 0.144
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.135
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.133
Wdr1 WD repeat domain 1 0.131
Pcolce procollagen C-endopeptidase enhancer protein 0.131
Hnrpdl heterogeneous nuclear ribonucleoprotein D-like 0.130
Rpl28 ribosomal protein L28 0.130
C3ar1 complement component 3a receptor 1 0.130
Kctd10 potassium channel tetramerisation domain containing 10 0.129
Ccl24 chemokine (C-C motif) ligand 24 0.125
AF251705 cDNA sequence AF251705 0.125
Mfn2 mitofusin 2 0.122
Phldb2 pleckstrin homology-like domain, family B, member 2 0.121
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.121
Rps5 ribosomal protein S5 0.119
Sfpi1 SFFV proviral integration 1 0.119
Msr1 macrophage scavenger receptor 1 0.119
Tmpo thymopoietin 0.116
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.115
Rpl7a ribosomal protein L7A 0.114
C1qb complement component 1, q subcomponent, beta polypeptide 0.108
Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.105
Ptk2 PTK2 protein tyrosine kinase 2 0.104
Actg2 actin, gamma 2, smooth muscle, enteric 0.102
Lmna lamin A 0.101
Tpm1 tropomyosin 1, alpha 0.101
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.100
Myh11 myosin, heavy polypeptide 11, smooth muscle 0.100
H2afz H2A histone family, member Z 0.098
Tpm4 tropomyosin 4 0.097
Aoah acyloxyacyl hydrolase 0.093
Rpl8 ribosomal protein L8 0.093
Cr2 complement receptor 2 0.091
Trem3 triggering receptor expressed on myeloid cells 3 0.091
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.090
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.090
Rplp1 ribosomal protein, large, P1 0.089
Tgfbr2 transforming growth factor, beta receptor II 0.087
Flt3 FMS-like tyrosine kinase 3 0.087
Vpreb3 pre-B lymphocyte gene 3 0.087
Clec5a C-type lectin domain family 5, member a 0.084
Cxcr2 chemokine (C-X-C motif) receptor 2 0.083
Mapkapk2 MAP kinase-activated protein kinase 2 0.083
Fpr1 formyl peptide receptor 1 0.081
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ndufa2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 0.020
Tomm7 translocase of outer mitochondrial membrane 7 homolog (yeast) 0.018
Atp5l ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G 0.017
Top1 topoisomerase (DNA) I 0.015
Cox7c cytochrome c oxidase, subunit VIIc 0.014
Churc1 churchill domain containing 1 0.012
Psma2 proteasome (prosome, macropain) subunit, alpha type 2 0.012
Ndufa13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.012
Atp5j2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 0.011
RGD1309735 similar to CG14977-PA 0.011
Timm8b translocase of inner mitochondrial membrane 8 homolog b (yeast) 0.011
Ndufs5 NADH dehydrogenase (ubiquinone) Fe-S protein 5 0.011
Atp6v1f ATPase, H transporting, lysosomal V1 subunit F 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism