The network for 'positive regulation of purine nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of purine nucleotide metabolic process

Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.

Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.853
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.802
Kl klotho 0.783
Ilk integrin linked kinase 0.664
Arrb2 arrestin, beta 2 0.643
Prkcc protein kinase C, gamma 0.640
Dnm1 dynamin 1 0.612
Plxnd1 plexin D1 0.578
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.572
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.523
Braf Braf transforming gene 0.513
Dlg4 discs, large homolog 4 (Drosophila) 0.503
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.489
Bax BCL2-associated X protein 0.476
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.457
Nckap1 NCK-associated protein 1 0.453
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.450
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.449
Pxn paxillin 0.447
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.443
Plxna1 plexin A1 0.442
Pparg peroxisome proliferator activated receptor gamma 0.406
Ctnnb1 catenin (cadherin associated protein), beta 1 0.401
Hmha1 histocompatibility (minor) HA-1 0.398
Fgf3 fibroblast growth factor 3 0.396
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.361
Fyn Fyn proto-oncogene 0.351
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.346
Sstr4 somatostatin receptor 4 0.345
Laptm5 lysosomal-associated protein transmembrane 5 0.343
Mkl1 MKL (megakaryoblastic leukemia)/myocardin-like 1 0.336
Lrp1 low density lipoprotein receptor-related protein 1 0.333
Bcl2 B-cell leukemia/lymphoma 2 0.332
Nf2 neurofibromatosis 2 0.331
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.329
Slc12a5 solute carrier family 12, member 5 0.327
Rac1 RAS-related C3 botulinum substrate 1 0.326
Rasgrp2 RAS, guanyl releasing protein 2 0.324
Nf1 neurofibromatosis 1 0.323
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.322
Arrb1 arrestin, beta 1 0.315
Git1 G protein-coupled receptor kinase-interactor 1 0.312
Sncb synuclein, beta 0.306
Pax8 paired box gene 8 0.304
Rarg retinoic acid receptor, gamma 0.301
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.300
Grb2 growth factor receptor bound protein 2 0.290
Gsk3b glycogen synthase kinase 3 beta 0.287
Arhgap30 Rho GTPase activating protein 30 0.282
Plekha4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 0.281
Bglap bone gamma carboxyglutamate protein 0.279
Sox10 SRY-box containing gene 10 0.277
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.276
Vav3 vav 3 oncogene 0.264
Nrbp2 nuclear receptor binding protein 2 0.259
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.254
Epn1 epsin 1 0.248
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.247
Tgfa transforming growth factor alpha 0.246
Adora2a adenosine A2a receptor 0.243
Gpr27 G protein-coupled receptor 27 0.241
Vdr vitamin D receptor 0.240
Shc3 src homology 2 domain-containing transforming protein C3 0.238
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.235
Cotl1 coactosin-like 1 (Dictyostelium) 0.233
Mgat3 mannoside acetylglucosaminyltransferase 3 0.232
Ntf3 neurotrophin 3 0.231
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.230
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.223
Apln apelin 0.223
Gata5 GATA binding protein 5 0.220
Avp arginine vasopressin 0.218
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.218
Syt10 synaptotagmin X 0.216
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.214
Ar androgen receptor 0.214
Pnpla2 patatin-like phospholipase domain containing 2 0.212
Oxt oxytocin 0.208
Pomc pro-opiomelanocortin-alpha 0.207
Kcnk4 potassium channel, subfamily K, member 4 0.206
Cplx2 complexin 2 0.204
Ccl7 chemokine (C-C motif) ligand 7 0.203
Efnb2 ephrin B2 0.203
Tcfcp2l1 transcription factor CP2-like 1 0.201
Drd2 dopamine receptor D2 0.198
Rgs14 regulator of G-protein signaling 14 0.194
Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 0.194
Nrp1 neuropilin 1 0.193
Irf5 interferon regulatory factor 5 0.191
Cplx1 complexin 1 0.190
Ptpre protein tyrosine phosphatase, receptor type, E 0.189
Rasa3 RAS p21 protein activator 3 0.188
Ccl12 chemokine (C-C motif) ligand 12 0.188
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.187
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.186
Rtkn rhotekin 0.184
Abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 0.184
Rasal3 RAS protein activator like 3 0.181
T brachyury 0.181
Tspan9 tetraspanin 9 0.181
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.231
CELE_F47G4.4 Protein F47G4.4 0.143
plc-3 Protein PLC-3 0.139
lag-1 Protein LAG-1 0.134
ttx-1 Protein TTX-1 0.086
lin-45 Protein LIN-45 0.080
sup-17 Protein SUP-17 0.079
unc-26 Protein UNC-26 0.062
fhod-1 Protein FHOD-1 0.060
eor-2 Protein EOR-2 0.059
pkg-1 Protein PKG-1 0.057
rig-6 Protein RIG-6 0.056
osm-5 Protein OSM-5 0.052
egl-15 Protein EGL-15 0.050
goa-1 Protein GOA-1 0.050
rme-4 Protein RME-4 0.047
zoo-1 Protein ZOO-1 0.047
pde-4 Protein PDE-4 0.046
egl-18 Protein EGL-18 0.046
pqn-39 Protein PQN-39 0.044
dpy-21 Protein DPY-21 0.043
egl-8 Protein EGL-8 0.041
unc-71 Protein UNC-71 0.039
egl-36 Protein EGL-36 0.038
mpk-1 Protein MPK-1 0.038
morc-1 Protein MORC-1 0.038
unc-53 Protein UNC-53 0.037
sol-1 Protein SOL-1 0.037
nck-1 Protein NCK-1 0.037
ptp-4 Protein PTP-4 0.036
crt-1 Protein CRT-1 0.035
sam-10 Protein SAM-10 0.033
syd-1 Protein SYD-1 0.033
dpf-3 Protein DPF-3 0.033
sma-6 Protein SMA-6 0.032
bet-2 Protein BET-2 0.031
F22D3.2 Protein F22D3.2 0.031
abl-1 Protein ABL-1 0.031
atfs-1 Protein ATFS-1 0.031
gly-7 Protein GLY-7 0.030
eef-1A.1 Protein EEF-1A.1 0.030
rpm-1 Protein RPM-1 0.030
cyld-1 Protein CYLD-1 0.029
aha-1 Protein AHA-1 0.029
CELE_T10D4.6 Protein T10D4.6 0.028
R11A8.7 Protein R11A8.7 0.028
ajm-1 Protein AJM-1 0.028
lin-48 Protein LIN-48 0.027
elt-6 Protein ELT-6 0.027
sto-4 Protein STO-4 0.027
rps-2 Protein RPS-2 0.027
egl-27 Protein EGL-27 0.027
pqm-1 Protein PQM-1 0.026
afd-1 Protein AFD-1 0.026
rsd-6 Protein RSD-6 0.026
T23F2.2 Protein T23F2.2 0.025
ZK418.7 Protein ZK418.7 0.025
F35G2.1 Protein F35G2.1 0.025
che-11 Protein CHE-11 0.025
C11E4.6 Protein C11E4.6 0.025
jnk-1 Protein JNK-1 0.025
cyc-1 Protein CYC-1 0.025
egrh-1 Protein EGRH-1 0.025
obr-3 Protein OBR-3 0.024
R90.1 Protein R90.1 0.024
ykt-6 Protein YKT-6 0.024
rbc-1 Protein RBC-1 0.024
mig-15 Protein MIG-15 0.024
T14B1.1 Protein T14B1.1 0.024
csnk-1 Protein CSNK-1 0.023
hel-1 Protein HEL-1 0.023
snf-1 Protein SNF-1 0.023
bar-1 Protein BAR-1 0.022
tmc-2 Protein TMC-2 0.022
rpb-7 Protein RPB-7 0.022
unc-115 Protein UNC-115 0.022
sad-1 Protein SAD-1 0.022
zfp-3 Protein ZFP-3 0.021
smp-1 Protein SMP-1 0.021
sma-9 Protein SMA-9 0.021
cor-1 Protein COR-1 0.021
W07B8.3 Protein W07B8.3 0.021
rsbp-1 Protein RSBP-1 0.021
chc-1 Protein CHC-1 0.021
unc-45 Protein UNC-45 0.020
miro-1 Protein MIRO-1 0.020
myo-2 Protein MYO-2 0.020
unc-62 Protein UNC-62 0.020
flh-2 Protein FLH-2 0.020
pak-1 Protein PAK-1 0.019
acr-2 Protein ACR-2 0.019
larp-5 Protein LARP-5 0.019
T27F6.6 Protein T27F6.6 0.019
F56D2.6 Protein F56D2.6 0.019
del-5 Protein DEL-5 0.019
tag-303 Protein TAG-303 0.018
rack-1 Protein RACK-1 0.018
CELE_M01B12.4 Protein M01B12.4 0.018
gar-3 Protein GAR-3 0.018
abts-1 Protein ABTS-1 0.018
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.404
hsp90a.2 heat shock protein 90-alpha 2 0.329
mc3r melanocortin 3 receptor 0.313
bcl2 B-cell leukemia/lymphoma 2 0.273
adrb2a adrenergic receptor, beta 2a 0.243
cnn2 calponin 2 0.222
pdlim1 PDZ and LIM domain 1 (elfin) 0.218
ncs1a neuronal calcium sensor 1a 0.196
rtcd1 RNA terminal phosphate cyclase domain 1 0.190
tpm4 tropomyosin 4 0.180
rtn1a reticulon 1a 0.152
mcl1b myeloid cell leukemia sequence 1b 0.125
atp2b1a ATPase, Ca++ transporting, plasma membrane 1a 0.114
hspa4a heat shock protein 4a 0.105
bida BH3 interacting domain death agonist 0.096
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.096
pvalb4 parvalbumin 4 0.078
pparg peroxisome proliferator activated receptor gamma 0.077
mc5ra melanocortin 5a receptor 0.075
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.075
nf1a neurofibromin 1a 0.074
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.074
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.062
nf1b neurofibromin 1b 0.061
jun jun proto-oncogene 0.058
rcn1 reticulocalbin 1, EF-hand calcium binding domain 0.058
cldnk claudin k 0.055
atp2a1l ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like 0.055
gclc glutamate-cysteine ligase, catalytic subunit 0.055
ptgs2a prostaglandin-endoperoxide synthase 2a 0.054
ahnak AHNAK nucleoprotein 0.052
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.051
tagln2 transgelin 2 0.050
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.050
oxtl oxytocin-like 0.049
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.047
tomm34 translocase of outer mitochondrial membrane 34 0.047
pvalb1 parvalbumin 1 0.047
wnt10b wingless-type MMTV integration site family, member 10b 0.046
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.042
rhag Rhesus blood group-associated glycoprotein 0.041
mylz3 myosin, light polypeptide 3, skeletal muscle 0.041
hoxc12b homeo box C12b 0.039
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.038
si:ch211-232m7.1 si:ch211-232m7.1 0.037
ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) 0.037
or115-10 odorant receptor, family F, subfamily 115, member 10 0.037
ccng1 cyclin G1 0.036
rps6ka3a ribosomal protein S6 kinase, polypeptide 3a 0.036
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.035
pvalb3 parvalbumin 3 0.033
tpm3 tropomyosin 3 0.033
mc1r melanocortin 1 receptor 0.032
rhoaa ras homolog gene family, member Aa 0.032
im:7137453 im:7137453 0.032
cldn12 claudin 12 0.032
zgc:162213 zgc:162213 0.031
aurka aurora kinase A 0.030
atf3 activating transcription factor 3 0.030
vangl2 vang-like 2 (van gogh, Drosophila) 0.030
icn ictacalcin 0.030
crb2a crumbs homolog 2a 0.029
junbl jun B proto-oncogene, like 0.028
rspo1 R-spondin homolog (Xenopus laevis) 0.028
dag1 dystroglycan 1 0.027
zgc:91930 zgc:91930 0.027
cebpd CCAAT/enhancer binding protein (C/EBP), delta 0.027
phlda2 pleckstrin homology-like domain, family A, member 2 0.027
nedd4l neural precursor cell expressed, developmentally down-regulated 4-like 0.026
abcf2 ATP-binding cassette, sub-family F (GCN20), member 2 0.026
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.025
cyp11b2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.025
socs3a suppressor of cytokine signaling 3a 0.024
bcl2l1 bcl2-like 1 0.024
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.023
nt5e 5'-nucleotidase, ecto (CD73) 0.023
flj13639 flj13639 0.022
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.022
pvalb8 parvalbumin 8 0.022
ctsba cathepsin B, a 0.022
anxa2a annexin A2a 0.021
zgc:101724 zgc:101724 0.021
wnt2ba wingless-type MMTV integration site family, member 2Ba 0.021
mcl1a myeloid cell leukemia sequence 1a 0.021
rhoab ras homolog gene family, member Ab 0.021
si:dkey-228g21.4 si:dkey-228g21.4 0.021
tnnt3b troponin T3b, skeletal, fast 0.020
pvalb2 parvalbumin 2 0.020
ahctf1 AT hook containing transcription factor 1 0.020
nr0b1 nuclear receptor subfamily 0, group B, member 1 0.020
opn4l opsin 4, like 0.020
fes feline sarcoma oncogene 0.020
nrl neural retina leucine zipper 0.020
cldni claudin i 0.019
rpsa ribosomal protein SA 0.019
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.019
pak2a p21 (CDKN1A)-activated kinase 2a 0.019
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.019
scinlb scinderin like b 0.019
cited3 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3 0.019
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
mbc myoblast city 0.490
Rheb CG1081 gene product from transcript CG1081-RA 0.484
stai stathmin 0.348
Stat92E Signal-transducer and activator of transcription protein at 92E 0.345
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.311
Shaw Shaker cognate w 0.250
Ric Ras which interacts with Calmodulin 0.217
Khc Kinesin heavy chain 0.207
Apc APC-like 0.204
Sbf SET domain binding factor 0.194
Gug Grunge 0.191
Pten CG5671 gene product from transcript CG5671-RB 0.178
dnc dunce 0.165
jumu jumeau 0.159
NaCP60E Na channel protein 60E 0.154
Wnk CG7177 gene product from transcript CG7177-RA 0.149
dos daughter of sevenless 0.148
rut rutabaga 0.147
CG7158 CG7158 gene product from transcript CG7158-RA 0.144
Pdp1 PAR-domain protein 1 0.144
CG11033 CG11033 gene product from transcript CG11033-RB 0.135
tau CG31057 gene product from transcript CG31057-RA 0.124
plexB plexin B 0.121
puc puckered 0.120
rok Rho-kinase 0.119
LIMK1 LIM-kinase1 0.119
rhea CG6831 gene product from transcript CG6831-RA 0.110
baz bazooka 0.109
neuroligin CG13772 gene product from transcript CG13772-RA 0.105
Nmdar1 NMDA receptor 1 0.103
cno canoe 0.101
Dap160 Dynamin associated protein 160 0.100
Cbl CG7037 gene product from transcript CG7037-RB 0.100
jeb jelly belly 0.098
CG32635 CG32635 gene product from transcript CG32635-RA 0.096
CycA Cyclin A 0.096
synj synaptojanin 0.095
mask multiple ankyrin repeats single KH domain 0.093
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.093
stg string 0.092
CG13253 CG13253 gene product from transcript CG13253-RB 0.088
Abi Abelson interacting protein 0.087
pod1 CG4532 gene product from transcript CG4532-RF 0.087
dome domeless 0.084
tutl turtle 0.082
CG6509 CG6509 gene product from transcript CG6509-RB 0.081
CG3573 CG3573 gene product from transcript CG3573-RA 0.081
Caki Calcium/calmodulin-dependent protein kinase 0.078
hig hikaru genki 0.078
Ank2 Ankyrin 2 0.075
p120ctn Adherens junction protein p120 0.072
CG1233 CG1233 gene product from transcript CG1233-RB 0.071
CG8334 CG8334 gene product from transcript CG8334-RA 0.071
RhoBTB CG5701 gene product from transcript CG5701-RA 0.071
Rho1 CG8416 gene product from transcript CG8416-RB 0.070
mys myospheroid 0.070
Act5C Actin 5C 0.068
lin lines 0.065
sec6 CG5341 gene product from transcript CG5341-RA 0.065
tim timeless 0.064
myoglianin CG1838 gene product from transcript CG1838-RD 0.063
raps rapsynoid 0.063
frc fringe connection 0.062
siz schizo 0.062
CG32772 CG32772 gene product from transcript CG32772-RC 0.062
hpo hippo 0.062
oys oysgedart 0.062
Marf Mitochondrial assembly regulatory factor 0.061
CG18437 CG18437 gene product from transcript CG18437-RB 0.061
Vps45 Vacuolar protein sorting 45 0.061
Tsc1 CG6147 gene product from transcript CG6147-RA 0.060
Flo-2 flotillin 2 0.060
lat latheo 0.058
Act57B Actin 57B 0.058
Tbh Tyramine beta hydroxylase 0.057
Mer Merlin 0.056
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.056
sima similar 0.056
Myo31DF Myosin 31DF 0.055
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.055
cdm cadmus 0.054
Actbeta Activin-beta 0.054
Cks30A Cyclin-dependent kinase subunit 30A 0.054
l(2)k16918 lethal (2) k16918 0.053
Hnf4 Hepatocyte nuclear factor 4 0.053
cta concertina 0.051
cenG1A centaurin gamma 1A 0.051
sec15 CG7034 gene product from transcript CG7034-RA 0.051
sec10 CG6159 gene product from transcript CG6159-RA 0.050
fd85E forkhead domain 85E 0.050
N Notch 0.050
unc-104 CG8566 gene product from transcript CG8566-RB 0.049
car carnation 0.049
Nmnat Nicotinamide mononucleotide adenylyltransferase 0.048
slpr slipper 0.048
Su(H) Suppressor of Hairless 0.048
Cf2 Chorion factor 2 0.048
Pkn Protein kinase related to protein kinase N 0.048
Mbs Myosin binding subunit 0.048
trn tartan 0.047
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.995
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.995
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.992
PTK2 PTK2 protein tyrosine kinase 2 0.980
EXOSC3 exosome component 3 0.979
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.964
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.945
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.944
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.940
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.937
PLCG1 phospholipase C, gamma 1 0.931
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.926
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.922
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.909
ARRB1 arrestin, beta 1 0.900
SFN stratifin 0.894
CCR5 chemokine (C-C motif) receptor 5 0.880
FGFR2 fibroblast growth factor receptor 2 0.880
CCL5 chemokine (C-C motif) ligand 5 0.849
S100A6 S100 calcium binding protein A6 0.836
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.833
DNM1 dynamin 1 0.830
RHOA ras homolog gene family, member A 0.808
ITSN1 intersectin 1 (SH3 domain protein) 0.802
DNM2 dynamin 2 0.800
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.794
IL8 interleukin 8 0.792
SOS1 son of sevenless homolog 1 (Drosophila) 0.792
RIN3 Ras and Rab interactor 3 0.759
EGFR epidermal growth factor receptor 0.743
NCF2 neutrophil cytosolic factor 2 0.735
FKBP4 FK506 binding protein 4, 59kDa 0.722
DOCK1 dedicator of cytokinesis 1 0.719
TNK2 tyrosine kinase, non-receptor, 2 0.703
JUN jun proto-oncogene 0.686
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.675
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.672
STAT5A signal transducer and activator of transcription 5A 0.667
CXCL2 chemokine (C-X-C motif) ligand 2 0.659
GRB2 growth factor receptor-bound protein 2 0.659
MT1A metallothionein 1A 0.645
FMNL1 formin-like 1 0.638
CBX1 chromobox homolog 1 0.635
NCKAP1 NCK-associated protein 1 0.627
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.623
GRB7 growth factor receptor-bound protein 7 0.622
GDI2 GDP dissociation inhibitor 2 0.621
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.620
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.614
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.606
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.602
S100A9 S100 calcium binding protein A9 0.602
S100A8 S100 calcium binding protein A8 0.597
NCK2 NCK adaptor protein 2 0.594
ABI1 abl-interactor 1 0.588
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.588
IFNG interferon, gamma 0.579
SH3RF1 SH3 domain containing ring finger 1 0.573
CCL4 chemokine (C-C motif) ligand 4 0.565
CXCL3 chemokine (C-X-C motif) ligand 3 0.562
ADRBK1 adrenergic, beta, receptor kinase 1 0.556
TSC1 tuberous sclerosis 1 0.516
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.508
DPP4 dipeptidyl-peptidase 4 0.506
NCK1 NCK adaptor protein 1 0.476
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.475
CRHR1 corticotropin releasing hormone receptor 1 0.465
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.459
DRD2 dopamine receptor D2 0.453
NOSTRIN nitric oxide synthase trafficker 0.452
MARK3 MAP/microtubule affinity-regulating kinase 3 0.449
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.448
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.442
PKN3 protein kinase N3 0.416
CCL2 chemokine (C-C motif) ligand 2 0.415
BCAR1 breast cancer anti-estrogen resistance 1 0.415
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.412
CYTIP cytohesin 1 interacting protein 0.412
BBS10 Bardet-Biedl syndrome 10 0.411
SELPLG selectin P ligand 0.410
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.409
CXCL5 chemokine (C-X-C motif) ligand 5 0.398
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.397
GABARAPL1 GABA(A) receptor-associated protein like 1 0.391
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.383
TRAF5 TNF receptor-associated factor 5 0.381
BAIAP2 BAI1-associated protein 2 0.363
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.363
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.361
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.360
CXCL11 chemokine (C-X-C motif) ligand 11 0.355
BIN1 bridging integrator 1 0.354
NCF1 neutrophil cytosolic factor 1 0.353
CCL3 chemokine (C-C motif) ligand 3 0.350
PLEC plectin 0.350
CCL8 chemokine (C-C motif) ligand 8 0.346
LAD1 ladinin 1 0.345
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.345
CCR7 chemokine (C-C motif) receptor 7 0.344
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.389
Fgfr1 Fibroblast growth factor receptor 1 0.377
S100a4 S100 calcium-binding protein A4 0.340
Acta2 smooth muscle alpha-actin 0.320
Ifitm3 interferon induced transmembrane protein 3 0.319
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.298
Syt7 synaptotagmin VII 0.296
Ccl2 chemokine (C-C motif) ligand 2 0.279
Anxa2 annexin A2 0.279
Adora2a adenosine A2a receptor 0.263
Flt1 FMS-related tyrosine kinase 1 0.251
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.207
Notch3 Notch homolog 3 (Drosophila) 0.204
Cd247 Cd247 molecule 0.201
Adora1 adenosine A1 receptor 0.200
Sirpa signal-regulatory protein alpha 0.189
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.179
Crhr1 corticotropin releasing hormone receptor 1 0.170
Wdfy1 WD repeat and FYVE domain containing 1 0.161
Akap1 A kinase (PRKA) anchor protein 1 0.159
Hrh3 histamine receptor H3 0.157
Dlg3 discs, large homolog 3 (Drosophila) 0.149
Hpca hippocalcin 0.142
Arpc2 actin related protein 2/3 complex, subunit 2 0.141
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.140
Camk4 calcium/calmodulin-dependent protein kinase IV 0.138
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.134
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.133
Tgfbr2 transforming growth factor, beta receptor II 0.131
Tacr3 tachykinin receptor 3 0.130
Mr1 major histocompatibility complex, class I-related 0.129
Prkch protein kinase C, eta 0.126
Stx2 syntaxin 2 0.126
Myo1c myosin IC 0.124
Lat linker for activation of T cells 0.124
Gria1 glutamate receptor, ionotropic, AMPA 1 0.124
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.122
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.122
Dmd dystrophin 0.122
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.120
Utrn utrophin 0.118
Prkcg protein kinase C, gamma 0.116
Fgf14 fibroblast growth factor 14 0.116
Fgf2 fibroblast growth factor 2 0.116
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.115
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.113
Timp3 TIMP metallopeptidase inhibitor 3 0.112
Arl1 ADP-ribosylation factor-like 1 0.112
Oxtr oxytocin receptor 0.110
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.108
Vip vasoactive intestinal peptide 0.107
Phkg1 phosphorylase kinase, gamma 1 0.106
Ddr1 discoidin domain receptor tyrosine kinase 1 0.104
Dnm2 dynamin 2 0.103
Gipc1 GIPC PDZ domain containing family, member 1 0.103
Lgals1 lectin, galactoside-binding, soluble, 1 0.103
Tagln transgelin 0.102
Copb1 coatomer protein complex, subunit beta 1 0.101
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.101
Jak2 Janus kinase 2 0.100
Odf4 outer dense fiber of sperm tails 4 0.100
Bok BCL2-related ovarian killer 0.096
Hk1 hexokinase 1 0.096
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.096
Adam2 ADAM metallopeptidase domain 2 0.095
Vipr2 vasoactive intestinal peptide receptor 2 0.095
Dnm1 dynamin 1 0.093
Pja2 praja 2, RING-H2 motif containing 0.092
Arpc1b actin related protein 2/3 complex, subunit 1B 0.091
Olr416 olfactory receptor 416 0.090
Cxcr5 chemokine (C-X-C motif) receptor 5 0.089
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.088
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.087
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.087
Clec11a C-type lectin domain family 11, member a 0.087
Sstr1 somatostatin receptor 1 0.087
Cfp complement factor properdin 0.086
Acrv1 acrosomal vesicle protein 1 0.085
Pdyn prodynorphin 0.085
Rab27a RAB27A, member RAS oncogene family 0.085
Pld2 phospholipase D2 0.085
Gpr176 G protein-coupled receptor 176 0.084
Ncr1 natural cytotoxicity triggering receptor 1 0.084
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.084
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.082
Gabra2 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 0.081
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.080
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.080
Rara retinoic acid receptor, alpha 0.080
Fam69b family with sequence similarity 69, member B 0.080
Amph amphiphysin 0.079
Akirin2 akirin 2 0.079
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.079
Cd86 CD86 molecule 0.079
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.079
Eif3d eukaryotic translation initiation factor 3, subunit D 0.078
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.077
Myl9 myosin, light chain 9, regulatory 0.077
Ngf nerve growth factor (beta polypeptide) 0.077
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.076
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SPA2 Spa2p 0.395
GYL1 Gyl1p 0.294
STE11 Ste11p 0.280
GCD6 Gcd6p 0.156
RHO1 Rho1p 0.123
SUI3 Sui3p 0.110
PKC1 Pkc1p 0.103
FYV8 Fyv8p 0.090
STI1 Sti1p 0.085
KEL1 Kel1p 0.075
CDC24 Cdc24p 0.068
FAR1 Far1p 0.063
YIP3 Yip3p 0.061
SEC16 Sec16p 0.060
VPS4 Vps4p 0.059
GLO3 Glo3p 0.058
ROM2 Rom2p 0.057
SUI2 Sui2p 0.057
MDS3 Mds3p 0.056
VPS15 Vps15p 0.054
MSG5 Msg5p 0.048
PEA2 Pea2p 0.046
MNN9 Mnn9p 0.044
TUS1 Tus1p 0.044
TOM1 Tom1p 0.043
FKH1 Fkh1p 0.043
ATG20 Atg20p 0.041
CHC1 Chc1p 0.041
SIA1 Sia1p 0.040
MKK1 Mkk1p 0.039
YHR033W hypothetical protein 0.039
BEM3 Bem3p 0.039
RPN14 Rpn14p 0.038
NUP49 Nup49p 0.038
YDL206W hypothetical protein 0.037
SLG1 Slg1p 0.037
SLT2 Slt2p 0.037
YRB1 Yrb1p 0.036
STE2 Ste2p 0.035
HOR2 Hor2p 0.035
SPR6 Spr6p 0.035
ATP1 Atp1p 0.034
SKT5 Skt5p 0.034
AKL1 Akl1p 0.033
STE4 Ste4p 0.033
BFR1 Bfr1p 0.032
SPE3 Spe3p 0.032
ITR2 Itr2p 0.032
INP53 Inp53p 0.031
YDR186C hypothetical protein 0.031
YPR148C hypothetical protein 0.031
HSV2 Hsv2p 0.031
CCZ1 Ccz1p 0.031
GDS1 Gds1p 0.030
SAC7 Sac7p 0.030
YIL055C hypothetical protein 0.030
INP52 Inp52p 0.030
SSK2 Ssk2p 0.030
DCD1 Dcd1p 0.030
SSL2 Ssl2p 0.030
VPS41 Vps41p 0.030
CDC50 Cdc50p 0.029
DOP1 Dop1p 0.029
TSC11 Tsc11p 0.028
CHS1 Chs1p 0.028
PTP2 Ptp2p 0.028
YPL066W hypothetical protein 0.028
YCR007C hypothetical protein 0.028
ARP10 Arp10p 0.027
MBF1 Mbf1p 0.027
YME1 Yme1p 0.027
PEF1 Pef1p 0.027
SWC7 Swc7p 0.027
NDE1 Nde1p 0.027
CUP2 Cup2p 0.027
BPT1 Bpt1p 0.027
CMK2 Cmk2p 0.027
URA3 Ura3p 0.026
SER2 Ser2p 0.026
YML002W hypothetical protein 0.026
AVO1 Avo1p 0.026
BUD8 Bud8p 0.026
YHR127W hypothetical protein 0.026
MTC4 Mtc4p 0.026
NOP10 Nop10p 0.026
TRR1 Trr1p 0.025
YLR264C-A hypothetical protein 0.025
CAM1 Cam1p 0.025
BEM2 Bem2p 0.025
SRD1 Srd1p 0.025
SAK1 Sak1p 0.024
AAP1 Aap1p 0.024
LEU2 Leu2p 0.024
PSD2 Psd2p 0.024
CLN3 Cln3p 0.024
YNL108C hypothetical protein 0.024
RGA2 Rga2p 0.024
MGR1 Mgr1p 0.024
YGR126W hypothetical protein 0.024
PRS2 Prs2p 0.024