The network for 'actin cytoskeleton organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

actin cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

Mus musculus
Name Description Probability Func Analog Organism
Ttn titin 0.999
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.998
Vasp vasodilator-stimulated phosphoprotein 0.998
Efnb2 ephrin B2 0.998
Ldb3 LIM domain binding 3 0.997
Vangl2 vang-like 2 (van gogh, Drosophila) 0.997
Actn2 actinin alpha 2 0.995
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.995
Ctnnb1 catenin (cadherin associated protein), beta 1 0.994
Wdr1 WD repeat domain 1 0.989
Src Rous sarcoma oncogene 0.986
Cbl Casitas B-lineage lymphoma 0.986
Fyn Fyn proto-oncogene 0.984
Cttn cortactin 0.983
Tnnt3 troponin T3, skeletal, fast 0.980
Capzb capping protein (actin filament) muscle Z-line, beta 0.979
Rac1 RAS-related C3 botulinum substrate 1 0.977
Ephb2 Eph receptor B2 0.976
Tagln transgelin 0.976
Actc1 actin, alpha, cardiac muscle 1 0.969
Gli2 GLI-Kruppel family member GLI2 0.965
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.962
Wwtr1 WW domain containing transcription regulator 1 0.960
Itga3 integrin alpha 3 0.959
Arpc4 actin related protein 2/3 complex, subunit 4 0.956
Cox6a2 cytochrome c oxidase, subunit VI a, polypeptide 2 0.952
Bcl2 B-cell leukemia/lymphoma 2 0.948
Ilk integrin linked kinase 0.945
Prkce protein kinase C, epsilon 0.944
Ptrf polymerase I and transcript release factor 0.940
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.939
Abi1 abl-interactor 1 0.935
Dnm1 dynamin 1 0.932
Ptch1 patched homolog 1 0.921
Zeb1 zinc finger E-box binding homeobox 1 0.921
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.919
Lmna lamin A 0.917
Vcl vinculin 0.911
Csf1 colony stimulating factor 1 (macrophage) 0.908
Hrc histidine rich calcium binding protein 0.904
Wasf2 WAS protein family, member 2 0.903
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.902
Apc adenomatosis polyposis coli 0.898
Enah enabled homolog (Drosophila) 0.897
Cnn2 calponin 2 0.891
Actb actin, beta 0.886
Tpm2 tropomyosin 2, beta 0.883
Mark4 MAP/microtubule affinity-regulating kinase 4 0.883
Vav1 vav 1 oncogene 0.881
Hdac7 histone deacetylase 7 0.877
Dmd dystrophin, muscular dystrophy 0.872
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.869
Plcg1 phospholipase C, gamma 1 0.862
Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta 0.861
Arrb2 arrestin, beta 2 0.854
Cd2ap CD2-associated protein 0.854
Myo6 myosin VI 0.854
Myl3 myosin, light polypeptide 3 0.850
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.845
Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 0.843
Dok1 docking protein 1 0.842
Grb2 growth factor receptor bound protein 2 0.840
Iqgap1 IQ motif containing GTPase activating protein 1 0.839
Ptk2 PTK2 protein tyrosine kinase 2 0.837
Smad4 MAD homolog 4 (Drosophila) 0.836
Rhog ras homolog gene family, member G 0.834
Cotl1 coactosin-like 1 (Dictyostelium) 0.833
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.832
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.830
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.822
Ptprc protein tyrosine phosphatase, receptor type, C 0.822
Casq2 calsequestrin 2 0.822
Myl9 myosin, light polypeptide 9, regulatory 0.811
S100a6 S100 calcium binding protein A6 (calcyclin) 0.804
Tnni2 troponin I, skeletal, fast 2 0.804
Msn moesin 0.804
Pgam2 phosphoglycerate mutase 2 0.801
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.801
Akt1 thymoma viral proto-oncogene 1 0.798
Shc1 src homology 2 domain-containing transforming protein C1 0.798
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.798
Ephb3 Eph receptor B3 0.797
Hspb7 heat shock protein family, member 7 (cardiovascular) 0.795
Pick1 protein interacting with C kinase 1 0.790
Ptpre protein tyrosine phosphatase, receptor type, E 0.788
Actn1 actinin, alpha 1 0.788
Acta2 actin, alpha 2, smooth muscle, aorta 0.787
Mmp15 matrix metallopeptidase 15 0.787
Nrap nebulin-related anchoring protein 0.784
Vegfa vascular endothelial growth factor A 0.780
Prkcb protein kinase C, beta 0.777
Lims1 LIM and senescent cell antigen-like domains 1 0.775
Mylk myosin, light polypeptide kinase 0.768
2310014H01Rik RIKEN cDNA 2310014H01 gene 0.766
Cd19 CD19 antigen 0.762
Cnn1 calponin 1 0.759
Dtna dystrobrevin alpha 0.756
Myom1 myomesin 1 0.756
Csrp1 cysteine and glycine-rich protein 1 0.756
Laptm5 lysosomal-associated protein transmembrane 5 0.754
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
atn-1 Protein ATN-1 0.674
pat-3 Protein PAT-3 0.492
unc-15 Protein UNC-15 0.413
sem-5 Protein SEM-5 0.370
act-4 Protein ACT-4 0.338
mlc-2 Protein MLC-2 0.325
twk-18 Protein TWK-18 0.297
csq-1 Protein CSQ-1 0.290
unc-112 Protein UNC-112 0.281
tag-232 Protein TAG-232 0.272
mig-2 Protein MIG-2 0.251
his-64 Protein HIS-64 0.249
scc-1 Protein SCC-1 0.241
CELE_C01G6.5 Protein C01G6.5 0.240
mpk-1 Protein MPK-1 0.239
pfn-3 Protein PFN-3 0.239
R90.1 Protein R90.1 0.239
pat-10 Protein PAT-10 0.238
unc-52 Protein UNC-52 0.238
spc-1 Protein SPC-1 0.230
ajm-1 Protein AJM-1 0.214
ace-3 Protein ACE-3 0.207
ess-2 Protein ESS-2 0.205
unc-43 Protein UNC-43 0.203
unc-60 Protein UNC-60 0.193
unc-16 Protein UNC-16 0.192
dpy-23 Protein DPY-23 0.190
his-1 Protein HIS-1 0.189
flh-1 Protein FLH-1 0.188
eat-6 Protein EAT-6 0.188
klp-7 Protein KLP-7 0.186
F14B8.6 Protein F14B8.6 0.186
inx-4 Protein INX-4 0.186
col-34 Protein COL-34 0.186
hlh-1 Protein HLH-1 0.183
T23E7.2 Protein T23E7.2 0.183
unc-40 Protein UNC-40 0.180
lin-36 Protein LIN-36 0.179
ubr-1 Protein UBR-1 0.178
act-2 Protein ACT-2 0.177
unc-45 Protein UNC-45 0.177
unc-115 Protein UNC-115 0.175
CELE_Y51A2D.14 Protein Y51A2D.14 0.172
unc-32 Protein UNC-32 0.171
ftr-1 Protein FTR-1 0.170
unc-27 Protein UNC-27 0.169
ost-1 Protein OST-1 0.168
ric-3 Protein RIC-3 0.166
ten-1 Protein TEN-1 0.166
myo-3 Protein MYO-3 0.163
erm-1 Protein ERM-1 0.161
pat-6 Protein PAT-6 0.161
vab-3 Protein VAB-3 0.158
ddb-1 Protein DDB-1 0.158
ttm-4 Protein TTM-4 0.156
tni-1 Protein TNI-1 0.155
mat-3 Protein MAT-3 0.153
npp-9 Protein NPP-9 0.150
sorb-1 Protein SORB-1 0.149
E01G6.2 Protein E01G6.2 0.149
tag-163 Protein TAG-163 0.148
col-147 Protein COL-147 0.148
M02D8.1 Protein M02D8.1 0.147
riok-1 Protein RIOK-1 0.147
dim-1 Protein DIM-1 0.146
skn-1 Protein SKN-1 0.144
ketn-1 Protein KETN-1 0.144
CELE_M03D4.4 Protein M03D4.4 0.141
cdc-42 Protein CDC-42 0.141
smp-1 Protein SMP-1 0.140
pha-4 Protein PHA-4 0.139
R06C1.4 Protein R06C1.4 0.139
syg-1 Protein SYG-1 0.138
plp-1 Protein PLP-1 0.137
abts-1 Protein ABTS-1 0.137
C13C4.5 Protein C13C4.5 0.133
his-46 Protein HIS-46 0.133
clr-1 Protein CLR-1 0.133
T28B4.1 Protein T28B4.1 0.132
zer-1 Protein ZER-1 0.132
C06A5.8 Protein C06A5.8 0.132
unc-9 Protein UNC-9 0.132
dnj-27 Protein DNJ-27 0.131
pme-1 Protein PME-1 0.131
hlb-1 Protein HLB-1 0.131
cysl-1 Protein CYSL-1 0.131
inx-15 Protein INX-15 0.130
ttyh-1 Protein TTYH-1 0.130
T04F8.6 Protein T04F8.6 0.130
alp-1 Protein ALP-1 0.128
his-5 Protein HIS-5 0.127
unc-36 Protein UNC-36 0.126
unc-96 Protein UNC-96 0.126
tnt-2 Protein TNT-2 0.126
ogt-1 Protein OGT-1 0.124
pat-4 Protein PAT-4 0.124
hcp-3 Protein HCP-3 0.123
inx-12 Protein INX-12 0.123
ZC449.5 Protein ZC449.5 0.121
sng-1 Protein SNG-1 0.121
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.990
tnnc1b troponin C type 1b (slow) 0.969
ttna titin a 0.933
tnnt3b troponin T3b, skeletal, fast 0.892
actn3b actinin alpha 3b 0.845
tnni2a.4 troponin I, skeletal, fast 2a.4 0.741
neb nebulin 0.719
dag1 dystroglycan 1 0.682
pak1 p21/Cdc42/Rac1-activated kinase 1 0.653
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.622
cnn2 calponin 2 0.607
kdrl kinase insert domain receptor like 0.603
actn2 actinin, alpha 2 0.597
atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.544
actc1b actin, alpha, cardiac muscle 1b 0.540
cmyb transcription factor cmyb 0.508
ttnb titin b 0.506
smyd1b SET and MYND domain containing 1b 0.488
efnb2a ephrin B2a 0.462
vmhc ventricular myosin heavy chain 0.454
tpm3 tropomyosin 3 0.447
lama4 laminin, alpha 4 0.425
mef2cb myocyte enhancer factor 2cb 0.425
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.423
zgc:66286 zgc:66286 0.414
notch3 notch homolog 3 0.412
ryr3 ryanodine receptor 3 0.411
alcamb activated leukocyte cell adhesion molecule b 0.404
myod1 myogenic differentiation 1 0.403
ckma creatine kinase, muscle a 0.377
arpc5b actin related protein 2/3 complex, subunit 5B 0.367
s100a10b S100 calcium binding protein A10b 0.354
pdlim7 PDZ and LIM domain 7 0.337
fn1 fibronectin 1 0.326
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.323
srl sarcalumenin 0.313
lamb2 laminin, beta 2 (laminin S) 0.302
mylz2 myosin, light polypeptide 2, skeletal muscle 0.298
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.295
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.283
myl1 myosin, light chain 1, alkali; skeletal, fast 0.281
xirp2a xin actin-binding repeat containing 2a 0.278
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.277
unc45b unc-45 homolog B (C. elegans) 0.276
cdh5 cadherin 5 0.272
scinla scinderin like a 0.253
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.250
myl7 myosin, light polypeptide 7, regulatory 0.249
itgb1b.2 integrin, beta 1b.2 0.248
hspb8 heat shock protein, alpha-crystallin-related, b8 0.244
smyhc1l slow myosin heavy chain 1, like 0.234
klfd Kruppel-like factor d 0.232
dlb deltaB 0.227
zgc:63587 zgc:63587 0.221
sox10 SRY-box containing gene 10 0.217
cotl1 coactosin-like 1 (Dictyostelium) 0.217
tpm4 tropomyosin 4 0.216
mdka midkine-related growth factor 0.214
tnni1al troponin I, skeletal, slow like 0.205
tmem38a transmembrane protein 38A 0.204
elovl1b elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b 0.204
si:ch211-212m21.5 si:ch211-212m21.5 0.203
tal1 T-cell acute lymphocytic leukemia 1 0.200
myf6 myogenic factor 6 0.198
tnnt2a troponin T2a, cardiac 0.198
mybpc3 myosin binding protein C, cardiac 0.197
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.196
myl9l myosin, light polypeptide 9, like 0.194
mtp microsomal triglyceride transfer protein 0.190
utrn utrophin 0.188
zeb1 zinc finger E-box binding homeobox 1 0.187
pak2a p21 (CDKN1A)-activated kinase 2a 0.182
krt8 keratin 8 0.181
bactin1 bactin1 0.181
myf5 myogenic factor 5 0.181
pdlim5 PDZ and LIM domain 5 0.180
limk1 LIM domain kinase 1 0.176
notch1b notch homolog 1b 0.172
ef1a elongation factor 1-alpha 0.170
itgb3b integrin beta 3b 0.170
gja3 gap junction protein, alpha 3 0.170
acvr1b activin A receptor, type IB 0.169
tnnt3a troponin T3a, skeletal, fast 0.167
actr3 ARP3 actin-related protein 3 homolog (yeast) 0.166
bmp4 bone morphogenetic protein 4 0.164
tnni1b troponin I, skeletal, slow b 0.164
cdc42 cell division cycle 42 0.163
pikfyve phosphoinositide kinase, FYVE finger containing 0.163
fli1b friend leukemia integration 1b 0.162
itgav integrin, alpha V 0.156
zgc:86759 zgc:86759 0.156
si:ch211-232m7.1 si:ch211-232m7.1 0.156
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.155
msna moesin a 0.154
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.153
ephb4b eph receptor B4b 0.151
pxn paxillin 0.150
myhz1.2 myosin, heavy polypeptide 1.2, skeletal muscle 0.150
lasp1 LIM and SH3 protein 1 0.150
flot2a flotillin 2a 0.150
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
chic chickadee 0.999
Rab11 Rab-protein 11 0.996
Ras85D Ras oncogene at 85D 0.995
mbc myoblast city 0.991
hep hemipterous 0.985
Rac1 CG2248 gene product from transcript CG2248-RA 0.983
Arp66B Actin-related protein 66B 0.981
pbl pebble 0.974
Atpalpha Na pump alpha subunit 0.966
rok Rho-kinase 0.964
WASp CG1520 gene product from transcript CG1520-RA 0.957
zip zipper 0.955
Lis-1 Lissencephaly-1 0.954
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.953
arm armadillo 0.947
Moe Moesin 0.938
stck steamer duck 0.933
Sra-1 specifically Rac1-associated protein 1 0.929
wupA wings up A 0.929
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.929
Rho1 CG8416 gene product from transcript CG8416-RB 0.922
Atg1 Autophagy-specific gene 1 0.911
sls sallimus 0.908
dsh dishevelled 0.904
flw flapwing 0.892
mys myospheroid 0.880
sti sticky 0.865
shot short stop 0.864
didum dilute class unconventional myosin 0.851
dock dreadlocks 0.851
sn singed 0.851
fz frizzled 0.849
CtBP C-terminal Binding Protein 0.847
nmo nemo 0.837
S6k RPS6-p70-protein kinase 0.835
Rac2 CG8556 gene product from transcript CG8556-RA 0.827
msn misshapen 0.826
Rala Ras-related protein 0.823
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.818
hts hu li tai shao 0.818
bsk basket 0.814
Prm Paramyosin 0.812
Tm2 Tropomyosin 2 0.811
Dhc64C Dynein heavy chain 64C 0.799
Gprk2 G protein-coupled receptor kinase 2 0.793
Chc Clathrin heavy chain 0.784
Actn alpha actinin 0.783
Arf51F ADP ribosylation factor 51F 0.776
Act5C Actin 5C 0.773
Mlc2 Myosin light chain 2 0.771
Ced-12 CG5336 gene product from transcript CG5336-RA 0.771
p120ctn Adherens junction protein p120 0.769
ovo CG6824 gene product from transcript CG6824-RE 0.768
CG3563 CG3563 gene product from transcript CG3563-RA 0.764
vav CG7893 gene product from transcript CG7893-RB 0.764
Cortactin CG3637 gene product from transcript CG3637-RA 0.761
chb chromosome bows 0.757
dia diaphanous 0.757
Jra Jun-related antigen 0.756
Abi Abelson interacting protein 0.754
par-1 CG8201 gene product from transcript CG8201-RA 0.745
tsr twinstar 0.734
egl egalitarian 0.731
kuz kuzbanian 0.728
cpb capping protein beta 0.727
Src64B Src oncogene at 64B 0.722
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.708
Cdc42 CG12530 gene product from transcript CG12530-RA 0.699
fu fused 0.699
baz bazooka 0.698
Sdc Syndecan 0.697
Sos Son of sevenless 0.690
egh egghead 0.689
wts warts 0.678
Mhc Myosin heavy chain 0.674
rut rutabaga 0.666
numb CG3779 gene product from transcript CG3779-RB 0.665
Act57B Actin 57B 0.664
rhea CG6831 gene product from transcript CG6831-RA 0.662
Act87E Actin 87E 0.662
foxo forkhead box, sub-group O 0.626
cindr CIN85 and CD2AP orthologue 0.623
sha shavenoid 0.617
dys dysfusion 0.616
frtz fritz 0.610
Hem HEM-protein 0.601
trio CG18214 gene product from transcript CG18214-RA 0.586
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.579
tw Protein O-mannosyltransferase 2 0.572
sqh spaghetti squash 0.566
cher cheerio 0.562
ben bendless 0.553
pod1 CG4532 gene product from transcript CG4532-RF 0.553
pll pelle 0.550
Pax Paxillin 0.545
l(2)gl lethal (2) giant larvae 0.545
BicD Bicaudal D 0.523
mp multiplexin 0.520
p130CAS CG1212 gene product from transcript CG1212-RA 0.520
sec5 CG8843 gene product from transcript CG8843-RA 0.519
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
GRB2 growth factor receptor-bound protein 2 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
FLNA filamin A, alpha 1.000
ZYX zyxin 1.000
EGFR epidermal growth factor receptor 1.000
MYH9 myosin, heavy chain 9, non-muscle 1.000
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.999
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.999
RHOA ras homolog gene family, member A 0.999
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.999
FN1 fibronectin 1 0.999
SH3KBP1 SH3-domain kinase binding protein 1 0.997
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.997
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.997
ACTN1 actinin, alpha 1 0.996
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.994
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.994
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.994
ILK integrin-linked kinase 0.994
NCK1 NCK adaptor protein 1 0.990
CFL1 cofilin 1 (non-muscle) 0.986
PLCG1 phospholipase C, gamma 1 0.982
TRIM63 tripartite motif containing 63 0.978
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.976
ACTB actin, beta 0.971
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.970
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.968
ANKRD28 ankyrin repeat domain 28 0.967
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.967
ACTN4 actinin, alpha 4 0.967
IQGAP1 IQ motif containing GTPase activating protein 1 0.964
GAS7 growth arrest-specific 7 0.962
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.960
LMNA lamin A/C 0.957
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.951
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.949
FYN FYN oncogene related to SRC, FGR, YES 0.945
ESR1 estrogen receptor 1 0.940
SFN stratifin 0.936
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.935
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.934
MSN moesin 0.932
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.931
GRB7 growth factor receptor-bound protein 7 0.927
WASL Wiskott-Aldrich syndrome-like 0.926
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.923
VAV1 vav 1 guanine nucleotide exchange factor 0.922
SORBS3 sorbin and SH3 domain containing 3 0.919
VCL vinculin 0.919
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.917
NEB nebulin 0.917
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.909
WIPF1 WAS/WASL interacting protein family, member 1 0.902
TPM1 tropomyosin 1 (alpha) 0.896
ZNF746 zinc finger protein 746 0.890
ABI1 abl-interactor 1 0.885
ARRB1 arrestin, beta 1 0.884
ARRB2 arrestin, beta 2 0.880
ITSN1 intersectin 1 (SH3 domain protein) 0.878
SOS1 son of sevenless homolog 1 (Drosophila) 0.870
FGFR2 fibroblast growth factor receptor 2 0.865
PDLIM7 PDZ and LIM domain 7 (enigma) 0.863
ACTG1 actin, gamma 1 0.853
TPM4 tropomyosin 4 0.851
ERBB2IP erbb2 interacting protein 0.850
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.847
VIM vimentin 0.843
NCK2 NCK adaptor protein 2 0.842
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.839
HCK hemopoietic cell kinase 0.837
TTN titin 0.836
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.834
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.830
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.824
THBS1 thrombospondin 1 0.815
JAG1 jagged 1 0.808
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.801
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.798
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.795
PLEC plectin 0.792
FLNB filamin B, beta 0.783
PTRF polymerase I and transcript release factor 0.782
SH3BP2 SH3-domain binding protein 2 0.782
PFN1 profilin 1 0.775
CAPZB capping protein (actin filament) muscle Z-line, beta 0.758
MYOZ1 myozenin 1 0.757
DNM2 dynamin 2 0.755
NOTCH1 notch 1 0.738
WDR1 WD repeat domain 1 0.734
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.730
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.715
CAV1 caveolin 1, caveolae protein, 22kDa 0.715
BCAR1 breast cancer anti-estrogen resistance 1 0.703
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.698
MYO9B myosin IXB 0.694
EPS15 epidermal growth factor receptor pathway substrate 15 0.686
PLXNB1 plexin B1 0.685
PALLD palladin, cytoskeletal associated protein 0.682
TNK2 tyrosine kinase, non-receptor, 2 0.679
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Wdr1 WD repeat domain 1 0.791
Efhd2 EF-hand domain family, member D2 0.680
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.623
Lmna lamin A 0.593
Myh9 myosin, heavy chain 9, non-muscle 0.500
Arf6 ADP-ribosylation factor 6 0.379
Tagln2 transgelin 2 0.377
Pfn1 profilin 1 0.361
Acta2 smooth muscle alpha-actin 0.345
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.341
Tagln transgelin 0.325
S100a8 S100 calcium binding protein A8 0.274
Hk1 hexokinase 1 0.264
Taok1 TAO kinase 1 0.257
Arpc2 actin related protein 2/3 complex, subunit 2 0.245
Cttn cortactin 0.235
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.235
Tpm3 tropomyosin 3, gamma 0.225
Fgf7 fibroblast growth factor 7 0.225
Actc1 actin, alpha, cardiac muscle 1 0.223
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.219
Emp1 epithelial membrane protein 1 0.212
Cfl1 cofilin 1, non-muscle 0.208
Ptma prothymosin alpha 0.190
Tpm2 tropomyosin 2, beta 0.188
Bcl2 B-cell CLL/lymphoma 2 0.185
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.179
Fgfr1 Fibroblast growth factor receptor 1 0.176
Csnk1a1 casein kinase 1, alpha 1 0.176
Cd37 CD37 molecule 0.175
Fkbp1a FK506 binding protein 1a 0.174
Rap1b RAP1B, member of RAS oncogene family 0.174
Nrarp Notch-regulated ankyrin repeat protein 0.170
Csrp1 cysteine and glycine-rich protein 1 0.168
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.163
Pls3 plastin 3 (T-isoform) 0.163
Cast calpastatin 0.162
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.159
Nckap1 NCK-associated protein 1 0.157
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.155
Ckm creatine kinase, muscle 0.153
Arpc1b actin related protein 2/3 complex, subunit 1B 0.148
Mprip myosin phosphatase Rho interacting protein 0.148
Hck hemopoietic cell kinase 0.147
Ptprc protein tyrosine phosphatase, receptor type, C 0.144
Myadm myeloid-associated differentiation marker 0.137
Actn4 actinin alpha 4 0.136
Ptafr platelet-activating factor receptor 0.134
Tmpo thymopoietin 0.133
Actn1 actinin, alpha 1 0.133
Rras Harvey rat sarcoma virus oncogene, subgroup R 0.133
Nos3 nitric oxide synthase 3, endothelial cell 0.131
Itgb1 integrin, beta 1 0.129
Flna filamin A, alpha 0.129
Anxa2 annexin A2 0.126
Vav1 vav 1 guanine nucleotide exchange factor 0.126
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.126
Edn1 endothelin 1 0.125
Elk3 ELK3, ETS-domain protein 0.124
Tcf4 transcription factor 4 0.123
Fam129b family with sequence similarity 129, member B 0.122
Mylpf myosin light chain, phosphorylatable, fast skeletal muscle 0.122
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.121
Myl9 myosin, light chain 9, regulatory 0.121
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.120
Exoc5 exocyst complex component 5 0.118
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.118
Efna5 ephrin A5 0.118
Mapk3 mitogen activated protein kinase 3 0.115
Jak2 Janus kinase 2 0.112
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.111
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.110
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult 0.108
Il1r1 interleukin 1 receptor, type I 0.107
Jub jub, ajuba homolog (Xenopus laevis) 0.107
Actb actin, beta 0.106
Laptm5 lysosomal protein transmembrane 5 0.106
LOC100360986 mCG1035404-like 0.105
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.104
Grb2 growth factor receptor bound protein 2 0.103
Iqgap1 IQ motif containing GTPase activating protein 1 0.103
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.101
Oprk1 opioid receptor, kappa 1 0.101
Egfl7 EGF-like-domain, multiple 7 0.099
Tpm1 tropomyosin 1, alpha 0.098
Myl12b myosin, light chain 12B, regulatory 0.097
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.097
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.096
Robo1 roundabout homolog 1 (Drosophila) 0.093
Rhoa ras homolog gene family, member A 0.093
Cd82 Cd82 molecule 0.093
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.092
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.092
Vasp vasodilator-stimulated phosphoprotein 0.092
N5 DNA binding protein N5 0.091
Cfp complement factor properdin 0.091
Col12a1 collagen, type XII, alpha 1 0.090
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.090
Actg2 actin, gamma 2, smooth muscle, enteric 0.087
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.086
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ABP1 Abp1p 1.000
ARP2 Arp2p 0.998
LAS17 Las17p 0.997
CDC24 Cdc24p 0.995
MYO5 Myo5p 0.995
ARC35 Arc35p 0.991
ARP3 Arp3p 0.989
SRV2 Srv2p 0.983
ACT1 Act1p 0.981
RHO1 Rho1p 0.976
SLA2 Sla2p 0.965
YPK1 Ypk1p 0.963
TPM1 Tpm1p 0.951
TSC11 Tsc11p 0.950
ARC40 Arc40p 0.943
SPA2 Spa2p 0.939
ARC18 Arc18p 0.938
BEM4 Bem4p 0.929
SSK1 Ssk1p 0.928
PRK1 Prk1p 0.926
BBC1 Bbc1p 0.918
RVS167 Rvs167p 0.914
BNI1 Bni1p 0.910
BEM3 Bem3p 0.908
BOI1 Boi1p 0.903
PBS2 Pbs2p 0.886
YSC84 Ysc84p 0.886
MOB1 Mob1p 0.869
LSB1 Lsb1p 0.859
ARC15 Arc15p 0.851
SYP1 Syp1p 0.822
CAP2 Cap2p 0.803
CDC12 Cdc12p 0.797
BEM2 Bem2p 0.791
AIP1 Aip1p 0.781
CMD1 Cmd1p 0.748
SAC6 Sac6p 0.744
BUD6 Bud6p 0.727
ENT2 Ent2p 0.699
GEA2 Gea2p 0.694
CRN1 Crn1p 0.669
VRP1 Vrp1p 0.669
ROM2 Rom2p 0.662
CAP1 Cap1p 0.618
CDC25 Cdc25p 0.606
ENA5 Ena5p 0.602
PAN1 Pan1p 0.570
PKC1 Pkc1p 0.535
END3 End3p 0.523
AQY2 Aqy2p 0.504
ARC19 Arc19p 0.496
SSK2 Ssk2p 0.493
MOB2 Mob2p 0.463
DBF2 Dbf2p 0.430
COF1 Cof1p 0.428
HYM1 Hym1p 0.428
CYK3 Cyk3p 0.417
SLM2 Slm2p 0.416
YPT1 Ypt1p 0.414
CDC50 Cdc50p 0.402
MSB4 Msb4p 0.397
MYO2 Myo2p 0.393
AIM3 Aim3p 0.382
SCP1 Scp1p 0.370
SLA1 Sla1p 0.368
INP52 Inp52p 0.362
RGD1 Rgd1p 0.361
STE11 Ste11p 0.354
ENA2 Ena2p 0.353
STE12 Ste12p 0.339
MLC1 Mlc1p 0.337
BFR1 Bfr1p 0.336
PPH21 Pph21p 0.331
SHO1 Sho1p 0.328
RGA2 Rga2p 0.325
CBK1 Cbk1p 0.320
CLA4 Cla4p 0.315
BSP1 Bsp1p 0.314
SCD5 Scd5p 0.314
PEF1 Pef1p 0.312
CDC1 Cdc1p 0.311
STE4 Ste4p 0.308
CDC10 Cdc10p 0.303
RLM1 Rlm1p 0.303
GIC1 Gic1p 0.287
BUD4 Bud4p 0.273
FAR1 Far1p 0.266
MYO1 Myo1p 0.256
SAC7 Sac7p 0.244
CAK1 Cak1p 0.242
TWF1 Twf1p 0.241
PFY1 Pfy1p 0.234
YDJ1 Ydj1p 0.229
KEL1 Kel1p 0.222
MYO4 Myo4p 0.221
CLB3 Clb3p 0.220
HOF1 Hof1p 0.220
CDC42 Cdc42p 0.219
TAO3 Tao3p 0.219
HKR1 Hkr1p 0.213