The network for 'regulation of actin filament based process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of actin filament based process

Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.

Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.984
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.980
Rac1 RAS-related C3 botulinum substrate 1 0.977
Ldb3 LIM domain binding 3 0.970
Efnb2 ephrin B2 0.967
Dab1 disabled homolog 1 (Drosophila) 0.962
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.954
Scn5a sodium channel, voltage-gated, type V, alpha 0.947
Pick1 protein interacting with C kinase 1 0.938
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.929
Src Rous sarcoma oncogene 0.920
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.911
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.885
Cttn cortactin 0.870
Akt1 thymoma viral proto-oncogene 1 0.870
Cbl Casitas B-lineage lymphoma 0.868
Dok1 docking protein 1 0.863
Plcg1 phospholipase C, gamma 1 0.847
Dlg4 discs, large homolog 4 (Drosophila) 0.840
Arpc4 actin related protein 2/3 complex, subunit 4 0.836
Pten phosphatase and tensin homolog 0.829
Wdr1 WD repeat domain 1 0.827
Apc adenomatosis polyposis coli 0.826
Ptk2 PTK2 protein tyrosine kinase 2 0.800
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.774
Gsk3b glycogen synthase kinase 3 beta 0.770
Capzb capping protein (actin filament) muscle Z-line, beta 0.763
Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like 0.755
Abi1 abl-interactor 1 0.748
Grb2 growth factor receptor bound protein 2 0.741
Was Wiskott-Aldrich syndrome homolog (human) 0.723
Pxn paxillin 0.720
Dnm1 dynamin 1 0.714
Csf1 colony stimulating factor 1 (macrophage) 0.659
Nos3 nitric oxide synthase 3, endothelial cell 0.650
Lrrk2 leucine-rich repeat kinase 2 0.641
Mpdz multiple PDZ domain protein 0.617
Ephb2 Eph receptor B2 0.615
Gja1 gap junction protein, alpha 1 0.612
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.575
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.569
Tjp1 tight junction protein 1 0.550
Fzd2 frizzled homolog 2 (Drosophila) 0.539
Itgb3 integrin beta 3 0.538
Ctnna1 catenin (cadherin associated protein), alpha 1 0.529
Ryr2 ryanodine receptor 2, cardiac 0.513
Vangl1 vang-like 1 (van gogh, Drosophila) 0.501
Clic1 chloride intracellular channel 1 0.495
Gab1 growth factor receptor bound protein 2-associated protein 1 0.494
Inpp5d inositol polyphosphate-5-phosphatase D 0.473
Cdh2 cadherin 2 0.469
Spnb1 spectrin beta 1 0.465
Actb actin, beta 0.464
Tgfb2 transforming growth factor, beta 2 0.450
Prkce protein kinase C, epsilon 0.447
Myo1c myosin IC 0.446
Cd44 CD44 antigen 0.443
Epha4 Eph receptor A4 0.438
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.436
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.433
Bcar1 breast cancer anti-estrogen resistance 1 0.429
Emp2 epithelial membrane protein 2 0.426
Nfe2l3 nuclear factor, erythroid derived 2, like 3 0.425
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.421
Laptm5 lysosomal-associated protein transmembrane 5 0.416
Ptpre protein tyrosine phosphatase, receptor type, E 0.411
Kitl kit ligand 0.409
Vangl2 vang-like 2 (van gogh, Drosophila) 0.407
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.402
Hcls1 hematopoietic cell specific Lyn substrate 1 0.398
Prkcb protein kinase C, beta 0.398
Des desmin 0.397
Rbbp7 retinoblastoma binding protein 7 0.395
Tpm4 tropomyosin 4 0.394
Wnt6 wingless-related MMTV integration site 6 0.389
Ephb3 Eph receptor B3 0.388
Arhgap1 Rho GTPase activating protein 1 0.382
Plcd1 phospholipase C, delta 1 0.381
Efs embryonal Fyn-associated substrate 0.376
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.375
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.374
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.372
Fzd6 frizzled homolog 6 (Drosophila) 0.367
Mapkap1 mitogen-activated protein kinase associated protein 1 0.359
Ppfia4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 0.356
Zap70 zeta-chain (TCR) associated protein kinase 0.354
Jup junction plakoglobin 0.352
Trp53 transformation related protein 53 0.351
Csrp1 cysteine and glycine-rich protein 1 0.345
Kalrn kalirin, RhoGEF kinase 0.342
Scn1a sodium channel, voltage-gated, type I, alpha 0.340
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.337
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.336
Irs1 insulin receptor substrate 1 0.334
Emid2 EMI domain containing 2 0.334
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.331
Dlg1 discs, large homolog 1 (Drosophila) 0.325
Fermt3 fermitin family homolog 3 (Drosophila) 0.321
Actn2 actinin alpha 2 0.321
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
ina-1 Protein INA-1 0.400
sem-5 Protein SEM-5 0.217
cdc-42 Protein CDC-42 0.213
unc-60 Protein UNC-60 0.208
CELE_Y45F10B.13 Protein Y45F10B.13 0.206
inx-13 Protein INX-13 0.164
tni-1 Protein TNI-1 0.153
sorb-1 Protein SORB-1 0.151
csn-5 Protein CSN-5 0.151
lat-1 Protein LAT-1 0.139
cap-1 Protein CAP-1 0.134
unc-45 Protein UNC-45 0.126
unc-15 Protein UNC-15 0.110
R11A8.7 Protein R11A8.7 0.108
sma-1 Protein SMA-1 0.103
myo-3 Protein MYO-3 0.102
rab-5 Protein RAB-5 0.102
atf-7 Protein ATF-7 0.092
CELE_W05H12.1 Protein W05H12.1 0.086
mep-1 Protein MEP-1 0.084
sax-3 Protein SAX-3 0.080
afd-1 Protein AFD-1 0.080
kin-4 Protein KIN-4 0.079
mpk-1 Protein MPK-1 0.078
T28B11.1 Protein T28B11.1 0.078
gsp-1 Protein GSP-1 0.078
goa-1 Protein GOA-1 0.072
unc-16 Protein UNC-16 0.070
twk-18 Protein TWK-18 0.069
pat-12 Protein PAT-12 0.067
alp-1 Protein ALP-1 0.066
mnp-1 Protein MNP-1 0.064
mig-2 Protein MIG-2 0.062
tag-343 Protein TAG-343 0.062
unc-68 Protein UNC-68 0.062
R90.1 Protein R90.1 0.061
lin-24 Protein LIN-24 0.061
lin-7 Protein LIN-7 0.060
egl-44 Protein EGL-44 0.059
F10E9.3 Protein F10E9.3 0.058
CELE_Y67A10A.9 Protein Y67A10A.9 0.056
CELE_B0238.10 Protein B0238.10 0.055
eps-8 Protein EPS-8 0.055
T21B6.3 Protein T21B6.3 0.053
xpo-1 Protein XPO-1 0.053
abts-1 Protein ABTS-1 0.052
egl-27 Protein EGL-27 0.052
unc-9 Protein UNC-9 0.052
alx-1 Protein ALX-1 0.051
gcs-1 Protein GCS-1 0.049
klp-3 Protein KLP-3 0.049
gei-18 Protein GEI-18 0.046
egl-46 Protein EGL-46 0.046
tmc-2 Protein TMC-2 0.046
kgb-1 Protein KGB-1 0.044
hipr-1 Protein HIPR-1 0.043
unc-112 Protein UNC-112 0.043
hbl-1 Protein HBL-1 0.043
stip-1 Protein STIP-1 0.042
F21C10.7 Protein F21C10.7 0.042
ost-1 Protein OST-1 0.041
csnk-1 Protein CSNK-1 0.040
CELE_T13H5.1 Protein T13H5.1 0.039
unc-41 Protein UNC-41 0.039
W06F12.2 Protein W06F12.2 0.038
let-60 Protein LET-60 0.037
cam-1 Protein CAM-1 0.037
zoo-1 Protein ZOO-1 0.036
praf-3 Protein PRAF-3 0.036
pry-1 Protein PRY-1 0.036
C54E4.2 Protein C54E4.2 0.035
par-6 Protein PAR-6 0.035
acy-1 Protein ACY-1 0.035
dlg-1 Protein DLG-1 0.034
ced-10 Protein CED-10 0.034
mek-2 Protein MEK-2 0.034
H43E16.1 Protein H43E16.1 0.034
par-1 Protein PAR-1 0.034
magi-1 Protein MAGI-1 0.033
mec-7 Protein MEC-7 0.033
T16G1.9 Protein T16G1.9 0.033
trim-9 Protein TRIM-9 0.033
M02D8.1 Protein M02D8.1 0.033
hmp-1 Protein HMP-1 0.033
C27H2.2 Protein C27H2.2 0.033
ttm-4 Protein TTM-4 0.032
unc-32 Protein UNC-32 0.032
atn-1 Protein ATN-1 0.031
pha-4 Protein PHA-4 0.031
let-2 Protein LET-2 0.030
T14B1.1 Protein T14B1.1 0.030
C06G1.5 Protein C06G1.5 0.029
ztf-22 Protein ZTF-22 0.029
unc-116 Protein UNC-116 0.029
F28E10.1 Protein F28E10.1 0.029
mig-5 Protein MIG-5 0.029
B0001.3 Protein B0001.3 0.028
CELE_T04H1.2 Protein T04H1.2 0.028
R148.3 Protein R148.3 0.028
T05G5.1 Protein T05G5.1 0.028
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
smyd1b SET and MYND domain containing 1b 0.732
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.620
cotl1 coactosin-like 1 (Dictyostelium) 0.502
itgb1b.2 integrin, beta 1b.2 0.233
msna moesin a 0.180
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.156
sept2 septin 2 0.139
tpm4 tropomyosin 4 0.074
pak2a p21 (CDKN1A)-activated kinase 2a 0.073
klf2b Kruppel-like factor 2b 0.071
kdrl kinase insert domain receptor like 0.071
itgb3b integrin beta 3b 0.067
snx12 sorting nexin 12 0.065
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.064
dsc2l desmocollin 2 like 0.063
ighm immunoglobulin heavy constant mu and immunoglobulin heavy constant mu 0.060
tpm3 tropomyosin 3 0.059
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.057
bactin1 bactin1 0.055
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.052
arpc5b actin related protein 2/3 complex, subunit 5B 0.047
mfn2 mitofusin 2 0.046
perp PERP, TP53 apoptosis effector 0.046
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.045
tnnc1b troponin C type 1b (slow) 0.044
lcp1 lymphocyte cytosolic plastin 1 0.043
ef1a elongation factor 1-alpha 0.041
csrp1a cysteine and glycine-rich protein 1a 0.040
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.038
myog myogenin 0.038
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.036
egfra epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 0.036
myl9l myosin, light polypeptide 9, like 0.036
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.036
wt1b wilms tumor 1b 0.035
LOC557072 caspase recruitment domain-containing protein 11-like 0.032
krt8 keratin 8 0.032
si:ch211-212m21.5 si:ch211-212m21.5 0.031
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.030
acvr1b activin A receptor, type IB 0.029
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.029
pycard PYD and CARD domain containing 0.029
lyz lysozyme 0.028
prickle1a prickle-like 1 (Drosophila) a 0.028
scinla scinderin like a 0.028
si:ch73-60e21.1 si:ch73-60e21.1 0.027
slit3 slit (Drosophila) homolog 3 0.027
atp1a2a ATPase, Na+/K+ transporting, alpha 2a polypeptide 0.027
tp63 tumor protein p63 0.026
nrp1a neuropilin 1a 0.026
fli1b friend leukemia integration 1b 0.026
fabp11a fatty acid binding protein 11a 0.026
icn ictacalcin 0.026
tal1 T-cell acute lymphocytic leukemia 1 0.025
mylz2 myosin, light polypeptide 2, skeletal muscle 0.024
spns2 spinster homolog 2 (Drosophila) 0.024
adrb2a adrenergic receptor, beta 2a 0.024
itgb1a integrin, beta 1a 0.023
jup junction plakoglobin 0.023
kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.023
csf3r colony stimulating factor 3 receptor (granulocyte) 0.022
tuba8l3 tubulin, alpha 8 like 3 0.022
cyt1 type I cytokeratin, enveloping layer 0.022
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.021
casz1 castor zinc finger 1 0.021
krt4 keratin 4 0.021
lims1 LIM and senescent cell antigen-like domains 1 0.021
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.021
zgc:153867 zgc:153867 0.021
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.021
pvrl1b poliovirus receptor-related 1b 0.021
fam3c family with sequence similarity 3, member C 0.021
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.020
pdlim1 PDZ and LIM domain 1 (elfin) 0.020
epb4.1l4 erythrocyte protein band 4.1-like 4 0.020
prdm14 PR domain containing 14 0.020
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.020
itgb1b integrin, beta 1b 0.019
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.019
mybpc3 myosin binding protein C, cardiac 0.019
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.019
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.019
krt5 keratin 5 0.019
irf6 interferon regulatory factor 6 0.018
zgc:100942 zgc:100942 0.018
pvalb8 parvalbumin 8 0.018
atp1b2b ATPase, Na+/K+ transporting, beta 2b polypeptide 0.018
ctnnb1 catenin (cadherin-associated protein), beta 1 0.018
wasa Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a 0.017
bnc2 basonuclin 2 0.017
mmp9 matrix metalloproteinase 9 0.017
acta1b actin, alpha 1b, skeletal muscle 0.017
igfbp3 insulin-like growth factor binding protein 3 0.016
gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 0.016
cmlc1 cardiac myosin light chain-1 0.016
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.016
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.016
vegfaa vascular endothelial growth factor Aa 0.016
ucp2 uncoupling protein 2 0.016
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.016
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Rho1 CG8416 gene product from transcript CG8416-RB 0.963
chic chickadee 0.934
Akt1 CG4006 gene product from transcript CG4006-RA 0.879
Rac1 CG2248 gene product from transcript CG2248-RA 0.877
Rab11 Rab-protein 11 0.877
usp ultraspiracle 0.826
cpb capping protein beta 0.795
cindr CIN85 and CD2AP orthologue 0.775
msn misshapen 0.716
katanin-60 katanin 60 0.657
zip zipper 0.657
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.644
Cdc42 CG12530 gene product from transcript CG12530-RA 0.626
aop anterior open 0.609
trc tricornered 0.599
Vrp1 Verprolin 1 0.566
flw flapwing 0.550
WASp CG1520 gene product from transcript CG1520-RA 0.484
CadN Cadherin-N 0.477
shot short stop 0.474
par-1 CG8201 gene product from transcript CG8201-RA 0.420
mbc myoblast city 0.409
Src64B Src oncogene at 64B 0.399
Sra-1 specifically Rac1-associated protein 1 0.397
bsk basket 0.396
Cortactin CG3637 gene product from transcript CG3637-RA 0.369
robo roundabout 0.322
rok Rho-kinase 0.320
sls sallimus 0.315
par-6 CG5884 gene product from transcript CG5884-RA 0.306
pbl pebble 0.300
baz bazooka 0.298
Rala Ras-related protein 0.287
sqh spaghetti squash 0.269
pod1 CG4532 gene product from transcript CG4532-RF 0.253
hep hemipterous 0.232
ena enabled 0.227
Arp66B Actin-related protein 66B 0.224
S6k RPS6-p70-protein kinase 0.223
drpr draper 0.214
htl heartless 0.210
ovo CG6824 gene product from transcript CG6824-RE 0.207
Dcr-2 Dicer-2 0.205
Hem HEM-protein 0.205
mys myospheroid 0.205
Arp14D Actin-related protein 14D 0.202
CG10641 CG10641 gene product from transcript CG10641-RA 0.201
trio CG18214 gene product from transcript CG18214-RA 0.200
tum tumbleweed 0.189
neur neuralized 0.184
dsh dishevelled 0.180
shn schnurri 0.177
Pak3 CG14895 gene product from transcript CG14895-RA 0.175
Abl Abl tyrosine kinase 0.169
tsr twinstar 0.166
Sos Son of sevenless 0.166
cta concertina 0.165
p120ctn Adherens junction protein p120 0.163
pan pangolin 0.157
alpha-Cat alpha Catenin 0.154
arm armadillo 0.143
Act57B Actin 57B 0.142
spi spitz 0.141
Cip4 CG15015 gene product from transcript CG15015-RA 0.128
spir spire 0.127
rst roughest 0.126
Lasp CG3849 gene product from transcript CG3849-RB 0.125
Eph Eph receptor tyrosine kinase 0.125
cher cheerio 0.120
flr flare 0.119
bif bifocal 0.118
Pak PAK-kinase 0.114
Actn alpha actinin 0.114
Shc SHC-adaptor protein 0.112
stck steamer duck 0.110
kst karst 0.109
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.108
Dad Daughters against dpp 0.107
CG6051 CG6051 gene product from transcript CG6051-RB 0.106
tutl turtle 0.104
how held out wings 0.102
Dhc64C Dynein heavy chain 64C 0.101
Zasp52 Z band alternatively spliced PDZ-motif protein 52 0.099
dia diaphanous 0.096
Jra Jun-related antigen 0.095
cora coracle 0.093
rhea CG6831 gene product from transcript CG6831-RA 0.092
Dap160 Dynamin associated protein 160 0.090
egl egalitarian 0.090
jar jaguar 0.090
Mical Molecule interacting with CasL 0.090
myoglianin CG1838 gene product from transcript CG1838-RD 0.088
cpa capping protein alpha 0.088
Pvr PDGF- and VEGF-receptor related 0.087
dlg1 discs large 1 0.087
CG11299 CG11299 gene product from transcript CG11299-RA 0.087
Arf51F ADP ribosylation factor 51F 0.086
Rab5 Rab-protein 5 0.083
CG32528 CG32528 gene product from transcript CG32528-RA 0.081
cno canoe 0.080
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
GRB2 growth factor receptor-bound protein 2 1.000
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 1.000
RHOA ras homolog gene family, member A 1.000
FYN FYN oncogene related to SRC, FGR, YES 1.000
ACTB actin, beta 0.999
SFN stratifin 0.996
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.994
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.993
EGFR epidermal growth factor receptor 0.992
CFL1 cofilin 1 (non-muscle) 0.992
ABI1 abl-interactor 1 0.990
GAS7 growth arrest-specific 7 0.988
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.982
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.981
MYH9 myosin, heavy chain 9, non-muscle 0.980
JUP junction plakoglobin 0.977
BAIAP2 BAI1-associated protein 2 0.975
NCK1 NCK adaptor protein 1 0.970
IQGAP1 IQ motif containing GTPase activating protein 1 0.969
SH3KBP1 SH3-domain kinase binding protein 1 0.969
ZYX zyxin 0.965
FLNA filamin A, alpha 0.955
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.951
VAV1 vav 1 guanine nucleotide exchange factor 0.946
TPM1 tropomyosin 1 (alpha) 0.945
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.937
WASL Wiskott-Aldrich syndrome-like 0.935
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.924
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.920
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.918
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.917
DLG4 discs, large homolog 4 (Drosophila) 0.905
ZNF746 zinc finger protein 746 0.889
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.889
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.888
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.884
ILK integrin-linked kinase 0.883
PKP3 plakophilin 3 0.868
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.854
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.849
S100A9 S100 calcium binding protein A9 0.846
ITSN1 intersectin 1 (SH3 domain protein) 0.843
SPRR2A small proline-rich protein 2A 0.841
NCKAP1 NCK-associated protein 1 0.812
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.803
SMAD2 SMAD family member 2 0.793
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.775
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.774
SOS1 son of sevenless homolog 1 (Drosophila) 0.755
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.747
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.727
KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 0.726
SNX9 sorting nexin 9 0.725
S100A11 S100 calcium binding protein A11 0.715
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.697
MPZL2 myelin protein zero-like 2 0.690
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.664
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.663
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.660
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.654
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.654
CAPZB capping protein (actin filament) muscle Z-line, beta 0.651
WIPF1 WAS/WASL interacting protein family, member 1 0.647
S100B S100 calcium binding protein B 0.635
DAAM1 dishevelled associated activator of morphogenesis 1 0.631
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.630
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.627
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.616
HCK hemopoietic cell kinase 0.612
CTTN cortactin 0.601
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.600
CAPNS1 calpain, small subunit 1 0.594
FN1 fibronectin 1 0.593
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.592
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.588
PALLD palladin, cytoskeletal associated protein 0.579
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.573
DSP desmoplakin 0.571
PDCD6IP programmed cell death 6 interacting protein 0.568
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.562
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.561
LIN7B lin-7 homolog B (C. elegans) 0.547
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.524
PDLIM7 PDZ and LIM domain 7 (enigma) 0.509
ACTN1 actinin, alpha 1 0.508
SPRY4 sprouty homolog 4 (Drosophila) 0.505
LMNA lamin A/C 0.491
DSG2 desmoglein 2 0.491
WASF1 WAS protein family, member 1 0.491
TPM4 tropomyosin 4 0.488
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.472
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.461
SCHIP1 schwannomin interacting protein 1 0.454
DNM2 dynamin 2 0.453
PRKCA protein kinase C, alpha 0.440
SPTB spectrin, beta, erythrocytic 0.438
S100A4 S100 calcium binding protein A4 0.435
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Efhd2 EF-hand domain family, member D2 0.671
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.578
Pfn1 profilin 1 0.444
Tagln transgelin 0.308
Rab1b RAB1B, member RAS oncogene family 0.270
Arpc2 actin related protein 2/3 complex, subunit 2 0.224
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.212
Arpc1b actin related protein 2/3 complex, subunit 1B 0.176
Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.169
Sirpa signal-regulatory protein alpha 0.157
Sri sorcin 0.149
Myl9 myosin, light chain 9, regulatory 0.133
Acta2 smooth muscle alpha-actin 0.130
Gja1 gap junction protein, alpha 1 0.118
Akt2 v-akt murine thymoma viral oncogene homolog 2 0.111
Syt8 synaptotagmin VIII 0.104
Myh9 myosin, heavy chain 9, non-muscle 0.100
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.096
Laptm5 lysosomal protein transmembrane 5 0.093
Tpm3 tropomyosin 3, gamma 0.088
Spt1 salivary protein 1 0.087
Wdr1 WD repeat domain 1 0.087
Gad2 glutamate decarboxylase 2 0.087
Coro1a coronin, actin binding protein 1A 0.082
Lcp1 lymphocyte cytosolic protein 1 0.082
Rap1b RAP1B, member of RAS oncogene family 0.082
Bcl2l1 Bcl2-like 1 0.079
Cyth1 cytohesin 1 0.079
Cav1 caveolin 1, caveolae protein 0.078
Glp1r glucagon-like peptide 1 receptor 0.078
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.077
Tpm2 tropomyosin 2, beta 0.076
Myh6 myosin, heavy chain 6, cardiac muscle, alpha 0.075
Hk1 hexokinase 1 0.074
Fkbp1a FK506 binding protein 1a 0.074
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.072
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.066
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.066
Casq2 calsequestrin 2 (cardiac muscle) 0.064
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.062
Tmpo thymopoietin 0.062
Dlg3 discs, large homolog 3 (Drosophila) 0.061
Anxa2 annexin A2 0.061
Cttn cortactin 0.061
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.061
Rims1 regulating synaptic membrane exocytosis 1 0.061
Shank2 SH3 and multiple ankyrin repeat domains 2 0.060
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.060
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.059
Ryr2 ryanodine receptor 2, cardiac 0.058
LOC100362824 caveolin 2-like 0.058
Cdc42 cell division cycle 42 (GTP binding protein) 0.057
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.057
Dgkg diacylglycerol kinase, gamma 0.055
Trib1 tribbles homolog 1 (Drosophila) 0.053
Grid2 glutamate receptor, ionotropic, delta 2 0.052
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.051
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.050
Tubb5 tubulin, beta 5 0.049
Ap2m1 adaptor-related protein complex 2, mu 1 subunit 0.049
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.048
Cd38 CD38 molecule 0.048
Grip1 glutamate receptor interacting protein 1 0.048
Dstn destrin 0.048
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.048
Cckar cholecystokinin A receptor 0.047
Smad7 SMAD family member 7 0.047
Lmna lamin A 0.047
Asph aspartate-beta-hydroxylase 0.047
Prg2 proteoglycan 2, bone marrow 0.047
Gria1 glutamate receptor, ionotropic, AMPA 1 0.046
Tagln2 transgelin 2 0.044
Taok1 TAO kinase 1 0.044
Ptma prothymosin alpha 0.043
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.043
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.042
Oprk1 opioid receptor, kappa 1 0.042
Eif4h eukaryotic translation initiation factor 4H 0.042
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.042
Gfra2 GDNF family receptor alpha 2 0.042
Csrp1 cysteine and glycine-rich protein 1 0.041
Rhoa ras homolog gene family, member A 0.041
Freq frequenin homolog (Drosophila) 0.041
Kalrn kalirin, RhoGEF kinase 0.041
Hand2 heart and neural crest derivatives expressed 2 0.040
Prkcd protein kinase C, delta 0.040
Myl1 myosin, light chain 1 0.040
Vegfa vascular endothelial growth factor A 0.040
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.039
Fgf7 fibroblast growth factor 7 0.039
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.039
Ptprc protein tyrosine phosphatase, receptor type, C 0.039
Map3k1 mitogen activated protein kinase kinase kinase 1 0.039
Capn9 calpain 9 0.039
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.039
Plau plasminogen activator, urokinase 0.038
Epn1 Epsin 1 0.038
Nos3 nitric oxide synthase 3, endothelial cell 0.038
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.038
Map1a microtubule-associated protein 1A 0.037
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ABP1 Abp1p 0.986
MYO5 Myo5p 0.985
ACT1 Act1p 0.848
CDC24 Cdc24p 0.829
SRV2 Srv2p 0.780
SSK2 Ssk2p 0.714
RHO1 Rho1p 0.682
BNI1 Bni1p 0.667
CAP2 Cap2p 0.638
ARC15 Arc15p 0.637
BEM3 Bem3p 0.615
LSB1 Lsb1p 0.558
BEM1 Bem1p 0.455
SPA2 Spa2p 0.454
SAC6 Sac6p 0.421
ARC35 Arc35p 0.333
CDC42 Cdc42p 0.300
ARP3 Arp3p 0.293
SLA2 Sla2p 0.291
BBC1 Bbc1p 0.287
ARP2 Arp2p 0.262
CYK3 Cyk3p 0.252
ARC40 Arc40p 0.245
LAS17 Las17p 0.228
PFY1 Pfy1p 0.228
RVS167 Rvs167p 0.214
BEM2 Bem2p 0.176
BUD6 Bud6p 0.166
ARC19 Arc19p 0.162
TOR1 Tor1p 0.153
BOI1 Boi1p 0.152
TPM1 Tpm1p 0.146
RDI1 Rdi1p 0.141
TWF1 Twf1p 0.140
GIC1 Gic1p 0.139
ARC18 Arc18p 0.134
HOF1 Hof1p 0.134
FAR1 Far1p 0.126
ROM2 Rom2p 0.123
NBP2 Nbp2p 0.122
APP1 App1p 0.105
AVO1 Avo1p 0.094
CAP1 Cap1p 0.089
BEM4 Bem4p 0.089
PBS2 Pbs2p 0.073
GIP4 Gip4p 0.068
BZZ1 Bzz1p 0.068
SSK1 Ssk1p 0.068
AIP1 Aip1p 0.062
FUS1 Fus1p 0.058
DCP2 Dcp2p 0.058
GYL1 Gyl1p 0.057
BOI2 Boi2p 0.055
PTC1 Ptc1p 0.054
ZDS1 Zds1p 0.053
KEL1 Kel1p 0.050
PEX13 Pex13p 0.050
PPH21 Pph21p 0.047
RSR1 Rsr1p 0.045
MLC1 Mlc1p 0.043
AIM7 Aim7p 0.042
SCP1 Scp1p 0.042
MOB2 Mob2p 0.042
LSB6 Lsb6p 0.042
PIN3 Pin3p 0.038
UGO1 Ugo1p 0.036
MKK1 Mkk1p 0.036
STE12 Ste12p 0.034
MDM32 Mdm32p 0.034
NUM1 Num1p 0.034
HYM1 Hym1p 0.033
STE7 Ste7p 0.030
BUD14 Bud14p 0.029
MYO4 Myo4p 0.028
PRS2 Prs2p 0.028
MER1 Mer1p 0.027
BCK1 Bck1p 0.027
GYP1 Gyp1p 0.026
ENT3 Ent3p 0.026
SSK22 Ssk22p 0.026
TEF1 Tef1p 0.026
FUS2 Fus2p 0.025
EXO70 Exo70p 0.025
PPH3 Pph3p 0.025
KOG1 Kog1p 0.025
ACK1 Ack1p 0.024
RGD1 Rgd1p 0.024
YLR162W hypothetical protein 0.024
COF1 Cof1p 0.024
YER134C hypothetical protein 0.023
AIM21 Aim21p 0.023
TOM1 Tom1p 0.023
RIO2 Rio2p 0.023
CLA4 Cla4p 0.022
PEF1 Pef1p 0.022
IRA1 Ira1p 0.022
YPK1 Ypk1p 0.022
YPL014W hypothetical protein 0.022
YNL058C hypothetical protein 0.021
KIN3 Kin3p 0.021