The network for 'mesonephric tubule development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mesonephric tubule development

The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.

Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 1.000
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Gli2 GLI-Kruppel family member GLI2 1.000
Wt1 Wilms tumor 1 homolog 1.000
Hoxd11 homeobox D11 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Bcl2 B-cell leukemia/lymphoma 2 1.000
Lhx1 LIM homeobox protein 1 1.000
Pten phosphatase and tensin homolog 1.000
Foxc1 forkhead box C1 1.000
Pax8 paired box gene 8 1.000
Fgfr1 fibroblast growth factor receptor 1 1.000
Bmp4 bone morphogenetic protein 4 1.000
Nos3 nitric oxide synthase 3, endothelial cell 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Bmp7 bone morphogenetic protein 7 1.000
Emx2 empty spiracles homolog 2 (Drosophila) 0.999
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.999
Hoxa11 homeobox A11 0.999
Gdnf glial cell line derived neurotrophic factor 0.999
Fgf8 fibroblast growth factor 8 0.998
Foxc2 forkhead box C2 0.997
Vegfa vascular endothelial growth factor A 0.996
Hand2 heart and neural crest derivatives expressed transcript 2 0.993
Ret ret proto-oncogene 0.992
Ren1 renin 1 structural 0.992
Pbx1 pre B-cell leukemia transcription factor 1 0.992
Trp53 transformation related protein 53 0.991
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.990
Tbx2 T-box 2 0.989
Pitx2 paired-like homeodomain transcription factor 2 0.987
Hif1a hypoxia inducible factor 1, alpha subunit 0.984
Hand1 heart and neural crest derivatives expressed transcript 1 0.984
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.983
Lepr leptin receptor 0.981
Sox9 SRY-box containing gene 9 0.979
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.979
Rarg retinoic acid receptor, gamma 0.979
Zeb1 zinc finger E-box binding homeobox 1 0.978
Hoxd9 homeobox D9 0.976
Wnt4 wingless-related MMTV integration site 4 0.975
Sox2 SRY-box containing gene 2 0.973
Msx1 homeobox, msh-like 1 0.973
Hoxd13 homeobox D13 0.972
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.970
Hoxa5 homeobox A5 0.968
Tcf21 transcription factor 21 0.968
Tbx3 T-box 3 0.968
Apc adenomatosis polyposis coli 0.968
Pou3f3 POU domain, class 3, transcription factor 3 0.967
Foxa2 forkhead box A2 0.966
Otx2 orthodenticle homolog 2 (Drosophila) 0.963
Smad3 MAD homolog 3 (Drosophila) 0.962
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.961
Vangl2 vang-like 2 (van gogh, Drosophila) 0.961
Tgfb2 transforming growth factor, beta 2 0.959
Efnb2 ephrin B2 0.957
Nog noggin 0.956
Meox2 mesenchyme homeobox 2 0.955
Ar androgen receptor 0.953
Sox7 SRY-box containing gene 7 0.950
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.947
Otx1 orthodenticle homolog 1 (Drosophila) 0.945
Hoxd4 homeobox D4 0.944
Dlg1 discs, large homolog 1 (Drosophila) 0.943
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.940
Lmx1a LIM homeobox transcription factor 1 alpha 0.939
Jag1 jagged 1 0.937
Gata4 GATA binding protein 4 0.937
Flt4 FMS-like tyrosine kinase 4 0.936
Gata6 GATA binding protein 6 0.931
Wnt6 wingless-related MMTV integration site 6 0.926
Pax3 paired box gene 3 0.925
Hoxb6 homeobox B6 0.921
Vhl von Hippel-Lindau tumor suppressor 0.920
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.920
Bnc1 basonuclin 1 0.919
Gdf5 growth differentiation factor 5 0.919
Hoxa10 homeobox A10 0.919
Fgfr3 fibroblast growth factor receptor 3 0.914
Ptgs2 prostaglandin-endoperoxide synthase 2 0.914
Pax6 paired box gene 6 0.910
Amhr2 anti-Mullerian hormone type 2 receptor 0.910
Hes5 hairy and enhancer of split 5 (Drosophila) 0.905
Lhx3 LIM homeobox protein 3 0.899
Sall4 sal-like 4 (Drosophila) 0.896
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.894
Emx1 empty spiracles homolog 1 (Drosophila) 0.892
Sox11 SRY-box containing gene 11 0.889
Kit kit oncogene 0.883
Wnt5a wingless-related MMTV integration site 5A 0.881
Adam17 a disintegrin and metallopeptidase domain 17 0.871
Rarb retinoic acid receptor, beta 0.865
Prrx2 paired related homeobox 2 0.852
Fgf10 fibroblast growth factor 10 0.840
T brachyury 0.838
Hoxb4 homeobox B4 0.838
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.836
Lef1 lymphoid enhancer binding factor 1 0.834
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 1.000
SMAD3 SMAD family member 3 1.000
SMAD2 SMAD family member 2 0.973
FGF1 fibroblast growth factor 1 (acidic) 0.973
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.959
SMAD1 SMAD family member 1 0.939
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.894
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.708
SMAD7 SMAD family member 7 0.570
RXRA retinoid X receptor, alpha 0.473
MEIS1 Meis homeobox 1 0.432
FGF10 fibroblast growth factor 10 0.363
MEIS2 Meis homeobox 2 0.355
EGR2 early growth response 2 0.348
SMAD9 SMAD family member 9 0.319
NKX2-1 NK2 homeobox 1 0.316
PLCG1 phospholipase C, gamma 1 0.293
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.232
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.231
FGF8 fibroblast growth factor 8 (androgen-induced) 0.210
HOXA10 homeobox A10 0.204
BMP7 bone morphogenetic protein 7 0.198
FSTL1 follistatin-like 1 0.190
SKIL SKI-like oncogene 0.185
MSN moesin 0.174
NOG noggin 0.169
CCNE1 cyclin E1 0.164
MEOX1 mesenchyme homeobox 1 0.152
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.147
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.124
COL2A1 collagen, type II, alpha 1 0.113
FGF18 fibroblast growth factor 18 0.111
MAGED2 melanoma antigen family D, 2 0.111
SMAD6 SMAD family member 6 0.105
ADAM17 ADAM metallopeptidase domain 17 0.092
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.091
TIMP3 TIMP metallopeptidase inhibitor 3 0.088
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.084
PJA1 praja ring finger 1 0.084
MED25 mediator complex subunit 25 0.084
PARVA parvin, alpha 0.080
HOXB5 homeobox B5 0.080
FGFR3 fibroblast growth factor receptor 3 0.073
WNT1 wingless-type MMTV integration site family, member 1 0.071
BCAM basal cell adhesion molecule (Lutheran blood group) 0.067
CPE carboxypeptidase E 0.062
NCOA1 nuclear receptor coactivator 1 0.059
PAX8 paired box 8 0.059
CXXC5 CXXC finger protein 5 0.058
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.058
NOTCH1 notch 1 0.057
FGF7 fibroblast growth factor 7 0.057
TGFBR1 transforming growth factor, beta receptor 1 0.057
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.055
ENG endoglin 0.054
CREBBP CREB binding protein 0.053
LBX1 ladybird homeobox 1 0.052
EGR1 early growth response 1 0.050
FGF3 fibroblast growth factor 3 0.050
BMP2 bone morphogenetic protein 2 0.048
FGFR1 fibroblast growth factor receptor 1 0.046
EGR3 early growth response 3 0.044
PTGIS prostaglandin I2 (prostacyclin) synthase 0.044
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.039
PAX2 paired box 2 0.039
INHBB inhibin, beta B 0.038
BMP4 bone morphogenetic protein 4 0.038
SMAD4 SMAD family member 4 0.036
FOS FBJ murine osteosarcoma viral oncogene homolog 0.035
FOXF2 forkhead box F2 0.035
SPRY2 sprouty homolog 2 (Drosophila) 0.034
FBLN1 fibulin 1 0.033
FZD7 frizzled homolog 7 (Drosophila) 0.033
LAPTM5 lysosomal protein transmembrane 5 0.033
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.033
PRKD2 protein kinase D2 0.033
HOXC8 homeobox C8 0.030
FOXF1 forkhead box F1 0.030
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.029
FGF4 fibroblast growth factor 4 0.029
HOXB6 homeobox B6 0.028
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.028
PBK PDZ binding kinase 0.027
AXIN1 axin 1 0.027
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.026
TGFB2 transforming growth factor, beta 2 0.026
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.025
HMGA2 high mobility group AT-hook 2 0.025
SFRP1 secreted frizzled-related protein 1 0.025
FGF2 fibroblast growth factor 2 (basic) 0.024
FOXA2 forkhead box A2 0.024
SIM2 single-minded homolog 2 (Drosophila) 0.023
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.023
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.023
SIX2 SIX homeobox 2 0.023
HOXA11 homeobox A11 0.022
JAG2 jagged 2 0.022
SPRY4 sprouty homolog 4 (Drosophila) 0.021
NCOA6 nuclear receptor coactivator 6 0.021
WT1 Wilms tumor 1 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.196
Pax8 paired box 8 0.183
Igf2 insulin-like growth factor 2 0.117
Gstm1 glutathione S-transferase mu 1 0.111
Ddr1 discoidin domain receptor tyrosine kinase 1 0.099
Galr2 galanin receptor 2 0.095
Efna5 ephrin A5 0.090
Shox2 short stature homeobox 2 0.088
Apc adenomatous polyposis coli 0.087
Hoxb7 homeo box B7 0.085
Prph2 peripherin 2 0.081
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.077
Unc5b unc-5 homolog B (C. elegans) 0.072
Foxd3 forkhead box D3 0.060
Sod3 superoxide dismutase 3, extracellular 0.055
Clec11a C-type lectin domain family 11, member a 0.054
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.051
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.050
Twist2 twist homolog 2 (Drosophila) 0.050
Ptger3 prostaglandin E receptor 3 (subtype EP3) 0.049
Mgst1 microsomal glutathione S-transferase 1 0.049
Pgcp plasma glutamate carboxypeptidase 0.047
Met met proto-oncogene 0.047
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.047
Col9a1 collagen, type IX, alpha 1 0.046
Galr1 galanin receptor 1 0.045
Lhx1 LIM homeobox 1 0.041
Pcdhgc3 protocadherin gamma subfamily C, 3 0.040
Irs1 insulin receptor substrate 1 0.039
Adrb1 adrenergic, beta-1-, receptor 0.039
Slit3 slit homolog 3 (Drosophila) 0.038
Gjd2 gap junction protein, delta 2 0.037
Smad7 SMAD family member 7 0.037
Col12a1 collagen, type XII, alpha 1 0.036
Lrpap1 low density lipoprotein receptor-related protein associated protein 1 0.036
Prrx1 paired related homeobox 1 0.035
Sox17 SRY (sex determining region Y)-box 17 0.034
Gata6 GATA binding protein 6 0.034
Nrg2 neuregulin 2 0.034
Nfia nuclear factor I/A 0.032
Fam65a family with sequence similarity 65, member A 0.031
Ephx1 epoxide hydrolase 1, microsomal 0.031
RT1-DOa RT1 class II, locus DOa 0.030
Gata3 GATA binding protein 3 0.029
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.028
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.028
Dchs1 dachsous 1 (Drosophila) 0.028
Mapk9 mitogen-activated protein kinase 9 0.028
Tpo thyroid peroxidase 0.027
Sdc2 syndecan 2 0.027
Pou3f2 POU class 3 homeobox 2 0.027
Sardh sarcosine dehydrogenase 0.026
Pkia protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.026
Hand2 heart and neural crest derivatives expressed 2 0.026
Baiap2 BAI1-associated protein 2 0.026
Hoxc4 homeo box C4 0.026
Mcam melanoma cell adhesion molecule 0.025
Tpsb2 tryptase beta 2 0.025
Ier3 immediate early response 3 0.025
Wt1 Wilms tumor 1 0.025
Bmp15 bone morphogenetic protein 15 0.025
Krt15 keratin 15 0.024
Grid2 glutamate receptor, ionotropic, delta 2 0.024
Clcn4-2 chloride channel 4-2 0.024
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.023
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.023
Lims1 LIM and senescent cell antigen-like domains 1 0.023
Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.023
Acvr1 activin A receptor, type I 0.022
Wnt6 wingless-type MMTV integration site family, member 6 0.022
Tcf12 transcription factor 12 0.021
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.021
Gria1 glutamate receptor, ionotropic, AMPA 1 0.021
Igfbp5 insulin-like growth factor binding protein 5 0.021
Zfp330 zinc finger protein 330 0.020
Pax4 paired box 4 0.020
Kcnk3 potassium channel, subfamily K, member 3 0.019
Kl Klotho 0.019
Neurod1 neurogenic differentiation 1 0.019
LOC100362331 rCG59612-like 0.019
Nxph3 neurexophilin 3 0.019
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.019
Ghr growth hormone receptor 0.019
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.018
Tbxa2r thromboxane A2 receptor 0.018
Megf10 multiple EGF-like domains 10 0.018
Bmp6 bone morphogenetic protein 6 0.018
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.018
Acacb acetyl-Coenzyme A carboxylase beta 0.018
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.018
Tcf21 transcription factor 21 0.017
Hoxa2 homeo box A2 0.017
Tgfbr2 transforming growth factor, beta receptor II 0.017
Sdc3 syndecan 3 0.017
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.017
Srd5a2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.017
Foxe3 forkhead box E3 0.017
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.017
Efnb1 ephrin B1 0.016
Krt18 keratin 18 0.016
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism