IMP
Process View
The network for 'negative regulation of myoblast differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of myoblast differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 0.998 | |
| Shh | sonic hedgehog | 0.995 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.975 | |
| Pax3 | paired box gene 3 | 0.975 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.961 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.960 | |
| Id3 | inhibitor of DNA binding 3 | 0.940 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.891 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.876 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.869 | |
| Ccl12 | chemokine (C-C motif) ligand 12 | 0.818 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.774 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.771 | |
| Id1 | inhibitor of DNA binding 1 | 0.766 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.742 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.734 | |
| Foxc1 | forkhead box C1 | 0.730 | |
| Jag1 | jagged 1 | 0.702 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.692 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.692 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.671 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.663 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.611 | |
| Ifng | interferon gamma | 0.584 | |
| Lta | lymphotoxin A | 0.581 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.528 | |
| Sox2 | SRY-box containing gene 2 | 0.509 | |
| Cd40 | CD40 antigen | 0.499 | |
| Sox11 | SRY-box containing gene 11 | 0.467 | |
| Fgf8 | fibroblast growth factor 8 | 0.464 | |
| Tcf3 | transcription factor 3 | 0.446 | |
| Meox2 | mesenchyme homeobox 2 | 0.435 | |
| Smo | smoothened homolog (Drosophila) | 0.428 | |
| Il6 | interleukin 6 | 0.424 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.413 | |
| Prrx2 | paired related homeobox 2 | 0.410 | |
| Nodal | nodal | 0.406 | |
| Tnf | tumor necrosis factor | 0.405 | |
| Bmp4 | bone morphogenetic protein 4 | 0.402 | |
| Efnb2 | ephrin B2 | 0.386 | |
| Tcfap2c | transcription factor AP-2, gamma | 0.378 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.348 | |
| Irg1 | immunoresponsive gene 1 | 0.348 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.343 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.334 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.329 | |
| Ltb | lymphotoxin B | 0.327 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.320 | |
| Irx3 | Iroquois related homeobox 3 (Drosophila) | 0.318 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.317 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.300 | |
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.300 | |
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.289 | |
| Il1b | interleukin 1 beta | 0.284 | |
| Dll1 | delta-like 1 (Drosophila) | 0.265 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.260 | |
| Ccl8 | chemokine (C-C motif) ligand 8 | 0.246 | |
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.245 | |
| Hesx1 | homeobox gene expressed in ES cells | 0.240 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.238 | |
| Sox9 | SRY-box containing gene 9 | 0.234 | |
| Irx1 | Iroquois related homeobox 1 (Drosophila) | 0.232 | |
| Foxg1 | forkhead box G1 | 0.227 | |
| Sox4 | SRY-box containing gene 4 | 0.216 | |
| Irx5 | Iroquois related homeobox 5 (Drosophila) | 0.216 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.197 | |
| Il7 | interleukin 7 | 0.197 | |
| Nog | noggin | 0.193 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.191 | |
| Irx2 | Iroquois related homeobox 2 (Drosophila) | 0.179 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.178 | |
| Prl7d1 | prolactin family 7, subfamily d, member 1 | 0.175 | |
| Prrx1 | paired related homeobox 1 | 0.172 | |
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.171 | |
| Sele | selectin, endothelial cell | 0.170 | |
| En1 | engrailed 1 | 0.164 | |
| Bmp7 | bone morphogenetic protein 7 | 0.158 | |
| Ch25h | cholesterol 25-hydroxylase | 0.157 | |
| Tcf7l1 | transcription factor 7-like 1 (T-cell specific, HMG box) | 0.155 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.154 | |
| Tbx5 | T-box 5 | 0.151 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.147 | |
| Ubd | ubiquitin D | 0.144 | |
| Il1rn | interleukin 1 receptor antagonist | 0.143 | |
| Tbx1 | T-box 1 | 0.142 | |
| Mmp3 | matrix metallopeptidase 3 | 0.142 | |
| Prl8a8 | prolactin family 8, subfamily a, member 81 | 0.141 | |
| Mmp12 | matrix metallopeptidase 12 | 0.140 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.136 | |
| Ntf3 | neurotrophin 3 | 0.134 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.130 | |
| Gata4 | GATA binding protein 4 | 0.127 | |
| Prl7c1 | prolactin family 7, subfamily c, member 1 | 0.122 | |
| Il1a | interleukin 1 alpha | 0.121 | |
| Foxc2 | forkhead box C2 | 0.116 | |
| Obox3 | oocyte specific homeobox 3 | 0.114 | |
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.113 | |
| Nf1 | neurofibromatosis 1 | 0.112 | |
| Ccl11 | chemokine (C-C motif) ligand 11 | 0.111 | |
| Sall4 | sal-like 4 (Drosophila) | 0.110 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| JAG1 | jagged 1 | 0.996 | |
| NOTCH1 | notch 1 | 0.840 | |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.495 | |
| FSTL1 | follistatin-like 1 | 0.469 | |
| NOTCH3 | notch 3 | 0.386 | |
| ATF3 | activating transcription factor 3 | 0.225 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.199 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.178 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.176 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.133 | |
| ENG | endoglin | 0.067 | |
| DLL1 | delta-like 1 (Drosophila) | 0.039 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.035 | |
| TRIM63 | tripartite motif containing 63 | 0.033 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.032 | |
| TTN | titin | 0.024 | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.024 | |
| TGFB3 | transforming growth factor, beta 3 | 0.023 | |
| JAG2 | jagged 2 | 0.019 | |
| NOTCH2 | notch 2 | 0.014 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.011 |