The network for 'heterocycle metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

heterocycle metabolic process

The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

Name Description Probability Func Analog Organism
pitx2 paired-like homeodomain transcription factor 2 0.994
osr1 odd-skipped related 1 (Drosophila) 0.984
notch1a notch homolog 1a 0.984
hhip hedgehog interacting protein 0.979
nanos3 nanos homolog 3 0.970
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.969
dlx2a distal-less homeobox gene 2a 0.968
tal1 T-cell acute lymphocytic leukemia 1 0.968
otx1b orthodenticle homolog 1b 0.962
pax6b paired box gene 6b 0.953
snai1b snail homolog 1b (Drosophila) 0.935
chd chordin 0.920
myod1 myogenic differentiation 1 0.920
klf4 Kruppel-like factor 4 0.919
bmp2b bone morphogenetic protein 2b 0.918
evx1 even-skipped homeobox 1 0.913
fgfr3 fibroblast growth factor receptor 3 0.907
otpa orthopedia homolog a 0.901
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.900
ndr2 nodal-related 2 0.896
six4b sine oculis homeobox homolog 4b 0.891
mbnl2 muscleblind-like 2 (Drosophila) 0.876
fsta follistatin a 0.875
fgf3 fibroblast growth factor 3 0.875
tll1 tolloid-like 1 0.869
lhx5 LIM homeobox 5 0.868
foxa2 forkhead box A2 0.867
spaw southpaw 0.862
ntla no tail a 0.861
gata6 GATA-binding protein 6 0.848
pax8 paired box gene 8 0.847
tbx1 T-box 1 0.845
cmyb transcription factor cmyb 0.836
wdr36 WD repeat domain 36 0.834
bmp4 bone morphogenetic protein 4 0.832
shha sonic hedgehog a 0.832
hoxb1b homeo box B1b 0.826
dkk1b dickkopf 1b 0.823
pcdh18b protocadherin 18b 0.817
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.815
vox ventral homeobox 0.808
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.801
myf5 myogenic factor 5 0.798
myog myogenin 0.788
fezf2 FEZ family zinc finger 2 0.788
otx1a orthodenticle homolog 1a 0.781
runx2b runt-related transcription factor 2b 0.774
lft1 lefty1 0.761
egr1 early growth response 1 0.759
gpia glucose phosphate isomerase a 0.755
mc2r melanocortin 2 receptor 0.755
alas2 aminolevulinate, delta-, synthetase 2 0.749
gata5 GATA-binding protein 5 0.746
hoxa13b homeo box A13b 0.743
plagl2 pleiomorphic adenoma gene-like 2 0.743
rx2 retinal homeobox gene 2 0.740
hnf1ba HNF1 homeobox Ba 0.739
nusap1 nucleolar and spindle associated protein 1 0.735
chrna6 cholinergic receptor, nicotinic, alpha 6 0.730
fgfr1b fibroblast growth factor receptor 1b 0.730
dlx5a distal-less homeobox gene 5a 0.728
rx3 retinal homeobox gene 3 0.728
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.724
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.719
six1b sine oculis homeobox homolog 1b 0.718
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.718
pkd2 polycystic kidney disease 2 0.713
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.713
smyhc1 slow myosin heavy chain 1 0.712
pax6a paired box gene 6a 0.712
wnt8b wingless-type MMTV integration site family, member 8b 0.706
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.704
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.704
sox2 SRY-box containing gene 2 0.703
runx2a runt-related transcription factor 2a 0.702
egr2b early growth response 2b 0.701
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.699
tbl3 transducin (beta)-like 3 0.694
snai1a snail homolog 1a (Drosophila) 0.693
eve1 even-skipped-like1 0.691
rnf2 ring finger protein 2 0.690
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.688
bdnf brain-derived neurotrophic factor 0.687
wt1a wilms tumor 1a 0.683
piwil1 piwi-like 1 (Drosophila) 0.681
fech ferrochelatase 0.681
pax7a paired box gene 7a 0.679
tgfb3 transforming growth factor, beta 3 0.675
mstnb myostatin b 0.671
neo1 neogenin 1 0.667
tp53 tumor protein p53 0.666
tbx18 T-box 18 0.664
smyhc2 slow myosin heavy chain 2 0.663
oxtl oxytocin-like 0.662
gli1 GLI-Kruppel family member 1 0.658
hoxc4a homeo box C4a 0.656
otpb orthopedia homolog b 0.653
gbx2 gastrulation brain homeo box 2 0.653
eng2a engrailed 2a 0.647
slit3 slit (Drosophila) homolog 3 0.645
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism