IMP

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Drosophila melanogaster

30 genes annotated in fly

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negative regulation of innate immune response

GO:0045824

Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of innate immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of innate immune response" (in gray)

Name	Description	Probability	Func Analog Organism
PGRP-LC	Peptidoglycan recognition protein LC	0.241	Fly
AttA	Attacin-A	0.179
Rel	Relish	0.158
PGRP-SA	Peptidoglycan recognition protein SA	0.093	Fly
Spn27A	Serpin 27A	0.072
PGRP-SD	CG7496 gene product from transcript CG7496-RA	0.070	Fly
DptB	Diptericin B	0.069
grass	Gram-positive Specific Serine protease	0.053
PGRP-LB	Peptidoglycan recognition protein LB	0.051	Fly
fon	fondue	0.051
Mad	Mothers against dpp	0.050
CG42863	CG42863 gene product from transcript CG42863-RB	0.049
Sp7	Serine protease 7	0.048
Mtk	Metchnikowin	0.046
PGRP-LF	Peptidoglycan recognition protein LF	0.043	Fly
CG15917	CG15917 gene product from transcript CG15917-RA	0.040
LysC	Lysozyme C	0.039
AttC	Attacin-C	0.039
CG6361	CG6361 gene product from transcript CG6361-RA	0.037
LysD	Lysozyme D	0.036	Fly
CG32185	CG32185 gene product from transcript CG32185-RA	0.034
PGRP-SC1a	CG14746 gene product from transcript CG14746-RA	0.034
tkv	thickveins	0.032	Fly
Drs	Drosomycin	0.030
pirk	poor Imd response upon knock-in	0.029
imd	immune deficiency	0.028
PGRP-SC1b	CG8577 gene product from transcript CG8577-RA	0.028
CG18594	CG18594 gene product from transcript CG18594-RA	0.027
SPE	Spatzle-Processing Enzyme	0.025
rl	rolled	0.024
CG9014	CG9014 gene product from transcript CG9014-RA	0.023
AGO2	Argonaute 2	0.023
Dredd	Death related ced-3/Nedd2-like protein	0.022
Pcaf	CG4107 gene product from transcript CG4107-RA	0.021
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.021
caz	cabeza	0.020
eater	CG6124 gene product from transcript CG6124-RB	0.020
CG17633	CG17633 gene product from transcript CG17633-RA	0.020
dm	diminutive	0.020
modSP	modular serine protease	0.019
IM18	Immune induced molecule 18	0.019
p38b	CG7393 gene product from transcript CG7393-RA	0.018
Spn1	Serine protease inhibitor 1	0.018
GNBP1	Gram-negative bacteria binding protein 1	0.018
psh	persephone	0.018
CG13060	CG13060 gene product from transcript CG13060-RA	0.017
Mpk2	CG5475 gene product from transcript CG5475-RB	0.017
Krn	Keren	0.017
cact	cactus	0.017
spirit	Serine Protease Immune Response Integrator	0.017
Irc	Immune-regulated catalase	0.016
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.016
foxo	forkhead box, sub-group O	0.016
Lmpt	Limpet	0.016
ird5	immune response deficient 5	0.016
ird1	immune response deficient 1	0.015
LysE	Lysozyme E	0.015
TepIII	Thiolester containing protein III	0.015
Pten	CG5671 gene product from transcript CG5671-RB	0.015
upd2	unpaired 2	0.014
He	Hemese	0.014
PGRP-LE	Peptidoglycan recognition protein LE	0.014	Fly
fh	frataxin homolog	0.014
CG9184	CG9184 gene product from transcript CG9184-RB	0.014
nimC1	nimrod C1	0.013
GNBP3	Gram-negative bacteria binding protein 3	0.013
skpA	CG16983 gene product from transcript CG16983-RD	0.013
CG1468	CG1468 gene product from transcript CG1468-RA	0.013
lic	licorne	0.013
CG6295	CG6295 gene product from transcript CG6295-RA	0.013
RagA	CG11968 gene product from transcript CG11968-RA	0.013
Pvf1	PDGF- and VEGF-related factor 1	0.013
CG30031	CG30031 gene product from transcript CG30031-RA	0.012
key	kenny	0.012
l(3)mbn	lethal (3) malignant blood neoplasm	0.012
epsilonTry	epsilonTrypsin	0.012
Thor	CG8846 gene product from transcript CG8846-RA	0.012
CecC	Cecropin C	0.012
Dpt	Diptericin	0.012
CG5791	CG5791 gene product from transcript CG5791-RA	0.012
Ance-4	CG8196 gene product from transcript CG8196-RA	0.012
CG11395	CG11395 gene product from transcript CG11395-RA	0.012
Myd88	CG2078 gene product from transcript CG2078-RA	0.012
smp-30	Senescence marker protein-30	0.012
Cyp12c1	CG4120 gene product from transcript CG4120-RA	0.011
CG13422	CG13422 gene product from transcript CG13422-RA	0.011
PGRP-SC2	CG14745 gene product from transcript CG14745-RA	0.011
CG13641	CG13641 gene product from transcript CG13641-RA	0.011
BG4	CG12297 gene product from transcript CG12297-RA	0.011
bam	bag of marbles	0.011
Gadd45	CG11086 gene product from transcript CG11086-RA	0.011
PGRP-SB1	CG9681 gene product from transcript CG9681-RA	0.011	Fly
Spn77Ba	Serpin 77Ba	0.011
Dro	Drosocin	0.011
CG12734	CG12734 gene product from transcript CG12734-RA	0.010
CG15065	CG15065 gene product from transcript CG15065-RA	0.010
Rbf	Retinoblastoma-family protein	0.010
pds5	CG17509 gene product from transcript CG17509-RA	0.010
coro	CG9446 gene product from transcript CG9446-RC	0.010
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.010
spz	spatzle	0.010
cv-2	crossveinless 2	0.010
Egm	Enigma	0.010
sm	smooth	0.010
Trx-2	thioredoxin-2	0.010