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Homo sapiens

32 genes annotated in human

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positive regulation of transporter activity

GO:0032411

Any process that activates or increases the activity of a transporter.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of transporter activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of transporter activity" (in gray)

Name	Description	Probability	Func Analog Organism
GSTM1	glutathione S-transferase mu 1	0.995	Human
GSTM2	glutathione S-transferase mu 2 (muscle)	0.982
S100B	S100 calcium binding protein B	0.922
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.701
GSTM4	glutathione S-transferase mu 4	0.700	Human
TBX5	T-box 5	0.626
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.402
NOXA1	NADPH oxidase activator 1	0.397
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.337
NCF1	neutrophil cytosolic factor 1	0.329
DTNA	dystrobrevin, alpha	0.323
FYN	FYN oncogene related to SRC, FGR, YES	0.282
KIAA1683	KIAA1683	0.276
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.260
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.244	Human
KLHL3	kelch-like 3 (Drosophila)	0.220
WNK1	WNK lysine deficient protein kinase 1	0.205	Human
ORAI1	ORAI calcium release-activated calcium modulator 1	0.155
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	0.138
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.133
ZYX	zyxin	0.128
MYOZ1	myozenin 1	0.114
RYR2	ryanodine receptor 2 (cardiac)	0.112
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.108
ADORA2A	adenosine A2a receptor	0.095
PDLIM1	PDZ and LIM domain 1	0.089
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.086
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.086
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.085	Mouse
CHUK	conserved helix-loop-helix ubiquitous kinase	0.084
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.084
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.083
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.081
MPDZ	multiple PDZ domain protein	0.079
GSTM3	glutathione S-transferase mu 3 (brain)	0.079	Human
SQSTM1	sequestosome 1	0.077
PRDX1	peroxiredoxin 1	0.076
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.074
TSC22D4	TSC22 domain family, member 4	0.067
SSTR2	somatostatin receptor 2	0.067	Human
MAPT	microtubule-associated protein tau	0.066
ACTN4	actinin, alpha 4	0.064	Human
AKAP6	A kinase (PRKA) anchor protein 6	0.064
MYO10	myosin X	0.061
SORBS2	sorbin and SH3 domain containing 2	0.061
MAPK4	mitogen-activated protein kinase 4	0.060
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.058
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.057	Human
ATXN1	ataxin 1	0.056
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.056
TRPC3	transient receptor potential cation channel, subfamily C, member 3	0.055	Human
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.053
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.053
TRIM63	tripartite motif containing 63	0.052
SSTR3	somatostatin receptor 3	0.052	Human
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.051
TRIM29	tripartite motif containing 29	0.049
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.047
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.046
DCTN1	dynactin 1	0.046
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.046
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.045
MMP23B	matrix metallopeptidase 23B	0.045
PDZK1	PDZ domain containing 1	0.043
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.043
ACTN1	actinin, alpha 1	0.041	Human
SOD1	superoxide dismutase 1, soluble	0.039
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.039
CDCP1	CUB domain containing protein 1	0.039
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.038
SH3RF1	SH3 domain containing ring finger 1	0.038
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.038
TP53	tumor protein p53	0.037
HMG20A	high mobility group 20A	0.037
DTNB	dystrobrevin, beta	0.037
BAG3	BCL2-associated athanogene 3	0.036
MYH9	myosin, heavy chain 9, non-muscle	0.036
AFF4	AF4/FMR2 family, member 4	0.035
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.035
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.035
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.035
PRKCZ	protein kinase C, zeta	0.035	Human
TPM4	tropomyosin 4	0.034
OXSR1	oxidative-stress responsive 1	0.034
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.033
SYNM	synemin, intermediate filament protein	0.033
ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	0.033
GPRASP1	G protein-coupled receptor associated sorting protein 1	0.032
ZNF71	zinc finger protein 71	0.032
PGAM1	phosphoglycerate mutase 1 (brain)	0.032
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.029
S100A1	S100 calcium binding protein A1	0.029	Rat
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.029
MYOM2	myomesin (M-protein) 2, 165kDa	0.028
DISC1	disrupted in schizophrenia 1	0.028
CYBA	cytochrome b-245, alpha polypeptide	0.027
CREBBP	CREB binding protein	0.027
SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.026
ILK	integrin-linked kinase	0.026
MAP7D1	MAP7 domain containing 1	0.026
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.025
DRD2	dopamine receptor D2	0.024	Human
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.024	Human
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.024
FLNA	filamin A, alpha	0.023
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.023
S100P	S100 calcium binding protein P	0.023
ZFYVE9	zinc finger, FYVE domain containing 9	0.022
PRKCB	protein kinase C, beta	0.022
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.021
RBBP5	retinoblastoma binding protein 5	0.021
TJP1	tight junction protein 1 (zona occludens 1)	0.021
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.021
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.021
TCAP	titin-cap (telethonin)	0.021
DAXX	death-domain associated protein	0.020
GFAP	glial fibrillary acidic protein	0.020
MAP1A	microtubule-associated protein 1A	0.020
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.019
GLIS2	GLIS family zinc finger 2	0.019
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.019
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.019
GOPC	golgi-associated PDZ and coiled-coil motif containing	0.019
CANX	calnexin	0.019
RAI1	retinoic acid induced 1	0.019
NDRG2	NDRG family member 2	0.019
PAM	peptidylglycine alpha-amidating monooxygenase	0.018
LASP1	LIM and SH3 protein 1	0.018
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.018	Mouse
CALD1	caldesmon 1	0.018
TTR	transthyretin	0.018
SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)	0.018
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.018
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.018
FHOD3	formin homology 2 domain containing 3	0.017
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.017
NRXN1	neurexin 1	0.017
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.017
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.017
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.017
CCDC115	coiled-coil domain containing 115	0.017
PDPK1	3-phosphoinositide dependent protein kinase-1	0.017
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.017
PICK1	protein interacting with PRKCA 1	0.017
CCL14	chemokine (C-C motif) ligand 14	0.016
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.016
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.016
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.016
DIAPH1	diaphanous homolog 1 (Drosophila)	0.016
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.016
OPRD1	opioid receptor, delta 1	0.016	Human
UTRN	utrophin	0.016
MYST1	MYST histone acetyltransferase 1	0.016
SH3GL2	SH3-domain GRB2-like 2	0.016
TRIM9	tripartite motif containing 9	0.015
DGCR14	DiGeorge syndrome critical region gene 14	0.015
TRPC6	transient receptor potential cation channel, subfamily C, member 6	0.015
MYBPC1	myosin binding protein C, slow type	0.015
TXN	thioredoxin	0.015
CTNND1	catenin (cadherin-associated protein), delta 1	0.015
TRAPPC1	trafficking protein particle complex 1	0.015
HSPB1	heat shock 27kDa protein 1	0.015
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.015
HIPK1	homeodomain interacting protein kinase 1	0.015
AR	androgen receptor	0.015
PDCD7	programmed cell death 7	0.015
PIAS4	protein inhibitor of activated STAT, 4	0.015
PRKCA	protein kinase C, alpha	0.015
BMPR1A	bone morphogenetic protein receptor, type IA	0.015
VCL	vinculin	0.014
ATP4A	ATPase, H+/K+ exchanging, alpha polypeptide	0.014
S100A6	S100 calcium binding protein A6	0.014
TRPC5	transient receptor potential cation channel, subfamily C, member 5	0.014	Human
AFF1	AF4/FMR2 family, member 1	0.014
TRIP6	thyroid hormone receptor interactor 6	0.014
TEF	thyrotrophic embryonic factor	0.014
FMNL2	formin-like 2	0.014
KCNJ3	potassium inwardly-rectifying channel, subfamily J, member 3	0.014
AGER	advanced glycosylation end product-specific receptor	0.014	Rat
PNMA1	paraneoplastic antigen MA1	0.014
TRPC4	transient receptor potential cation channel, subfamily C, member 4	0.014	Human
HRH3	histamine receptor H3	0.013
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.013
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.013
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.013
KIAA1377	KIAA1377	0.013
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.013
PGM5	phosphoglucomutase 5	0.013
PYGM	phosphorylase, glycogen, muscle	0.013
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	0.013
MAP1B	microtubule-associated protein 1B	0.013
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
HNF1A	HNF1 homeobox A	0.013
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.013
CNN2	calponin 2	0.013
FKBP1A	FK506 binding protein 1A, 12kDa	0.013
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.013
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.013
S100A11	S100 calcium binding protein A11	0.012
FOXO3	forkhead box O3	0.012
KEAP1	kelch-like ECH-associated protein 1	0.012
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.012
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.012
LDLR	low density lipoprotein receptor	0.012
FLNC	filamin C, gamma	0.012
NOS1	nitric oxide synthase 1 (neuronal)	0.012
HRC	histidine rich calcium binding protein	0.012
ATXN2	ataxin 2	0.012
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.012
ATOX1	ATX1 antioxidant protein 1 homolog (yeast)	0.012
STIM1	stromal interaction molecule 1	0.012
MAP2	microtubule-associated protein 2	0.012
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.012
PRDX2	peroxiredoxin 2	0.012
LDHA	lactate dehydrogenase A	0.012
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.012
SEPT11	septin 11	0.012
LDB3	LIM domain binding 3	0.012
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.012
NUMB	numb homolog (Drosophila)	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
CLTC	clathrin, heavy chain (Hc)	0.012
SESN2	sestrin 2	0.012
DSCAML1	Down syndrome cell adhesion molecule like 1	0.012
DMD	dystrophin	0.012	Mouse
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.012
ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	0.011
WDR1	WD repeat domain 1	0.011
IL1RAP	interleukin 1 receptor accessory protein	0.011
TLN1	talin 1	0.011
ANK2	ankyrin 2, neuronal	0.011	Mouse
ARRB2	arrestin, beta 2	0.011
SST	somatostatin	0.011
PRLHR	prolactin releasing hormone receptor	0.011
EZR	ezrin	0.011
GLA	galactosidase, alpha	0.011
ATM	ataxia telangiectasia mutated	0.011
ASXL2	additional sex combs like 2 (Drosophila)	0.011
GHRHR	growth hormone releasing hormone receptor	0.011
CHD8	chromodomain helicase DNA binding protein 8	0.011
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.011
HIPK2	homeodomain interacting protein kinase 2	0.011
S100A4	S100 calcium binding protein A4	0.011
NDFIP2	Nedd4 family interacting protein 2	0.011
FOXO1	forkhead box O1	0.011
GATA5	GATA binding protein 5	0.011
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.011
NKPD1	NTPase, KAP family P-loop domain containing 1	0.011
TRAF6	TNF receptor-associated factor 6	0.011
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.011
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.011
TMEM47	transmembrane protein 47	0.011
CORT	cortistatin	0.011
PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	0.011
TSC22D1	TSC22 domain family, member 1	0.011
STIM2	stromal interaction molecule 2	0.011
NCOA3	nuclear receptor coactivator 3	0.011
CABP1	calcium binding protein 1	0.011
SH2D1A	SH2 domain containing 1A	0.011
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.011
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.010
NCOA1	nuclear receptor coactivator 1	0.010
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.010
PRSS23	protease, serine, 23	0.010
FAM189A2	family with sequence similarity 189, member A2	0.010
MORF4L1	mortality factor 4 like 1	0.010
FKBP1B	FK506 binding protein 1B, 12.6 kDa	0.010
BBX	bobby sox homolog (Drosophila)	0.010
SPRR2A	small proline-rich protein 2A	0.010
POFUT1	protein O-fucosyltransferase 1	0.010
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.010
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.010
NCOA2	nuclear receptor coactivator 2	0.010
UROD	uroporphyrinogen decarboxylase	0.010
CCNT1	cyclin T1	0.010
ADAM11	ADAM metallopeptidase domain 11	0.010
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.010
SOX1	SRY (sex determining region Y)-box 1	0.010
IL1RAPL1	interleukin 1 receptor accessory protein-like 1	0.010
ACVR1B	activin A receptor, type IB	0.010