IMP

Process View

Homo sapiens

22 genes annotated in human

Multi-species View

glucan metabolic process

GO:0044042

The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glucan metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glucan metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	0.999
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.996	Yeast
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.965	Yeast
IRS2	insulin receptor substrate 2	0.887
IRS1	insulin receptor substrate 1	0.875
GRB10	growth factor receptor-bound protein 10	0.841	Rat
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.771
IGF1R	insulin-like growth factor 1 receptor	0.752	Human
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.693
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.683
PGK1	phosphoglycerate kinase 1	0.611
ALDOA	aldolase A, fructose-bisphosphate	0.534
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.489	Human
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.458
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.405
GSK3B	glycogen synthase kinase 3 beta	0.368
AR	androgen receptor	0.346
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.341
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.304
HIPK2	homeodomain interacting protein kinase 2	0.300
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.236
VCP	valosin containing protein	0.217
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.189
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.184
GYS1	glycogen synthase 1 (muscle)	0.180
NOXA1	NADPH oxidase activator 1	0.176
KAT2B	K(lysine) acetyltransferase 2B	0.174
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.164
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.157
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.154	Yeast
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.151	Worm
LZTS2	leucine zipper, putative tumor suppressor 2	0.142
ITGB1BP3	integrin beta 1 binding protein 3	0.138
ENO1	enolase 1, (alpha)	0.115
HR	hairless homolog (mouse)	0.115
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.112	Human
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.107
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.106
BTRC	beta-transducin repeat containing	0.095
GPI	glucose-6-phosphate isomerase	0.095
SH3RF1	SH3 domain containing ring finger 1	0.091
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.082
LDHA	lactate dehydrogenase A	0.077
PKM2	pyruvate kinase, muscle	0.075
GYG1	glycogenin 1	0.072	Yeast
STAT5B	signal transducer and activator of transcription 5B	0.069
CREBBP	CREB binding protein	0.063
UBXN2A	UBX domain protein 2A	0.063
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.062	Worm
NCOA2	nuclear receptor coactivator 2	0.061
NCOA1	nuclear receptor coactivator 1	0.061
TPI1	triosephosphate isomerase 1	0.061
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.058	Human
GBAS	glioblastoma amplified sequence	0.057
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.057
CDCP1	CUB domain containing protein 1	0.055
PRKCZ	protein kinase C, zeta	0.054	Human
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.054
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.054
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.053
PICK1	protein interacting with PRKCA 1	0.052
IGF2R	insulin-like growth factor 2 receptor	0.051
SH2B1	SH2B adaptor protein 1	0.050
NCOA6	nuclear receptor coactivator 6	0.049
GYG2	glycogenin 2	0.043	Yeast
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.043
HNF4A	hepatocyte nuclear factor 4, alpha	0.042
SFN	stratifin	0.042	Yeast
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.041
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.040
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.040
PRKCA	protein kinase C, alpha	0.037
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.035
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.033
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.033
OSBP	oxysterol binding protein	0.033
GCKR	glucokinase (hexokinase 4) regulator	0.032
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.029
JAK2	Janus kinase 2	0.028
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.027	Yeast
PRKCB	protein kinase C, beta	0.027
SETDB1	SET domain, bifurcated 1	0.027
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.026
CREB1	cAMP responsive element binding protein 1	0.026
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.026
HMOX2	heme oxygenase (decycling) 2	0.026
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.025
INPPL1	inositol polyphosphate phosphatase-like 1	0.024
IL6R	interleukin 6 receptor	0.023
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.023
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.023
ATXN3	ataxin 3	0.022
RAB6A	RAB6A, member RAS oncogene family	0.021
SRSF5	serine/arginine-rich splicing factor 5	0.021
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.021
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.021
RPTOR	regulatory associated protein of MTOR, complex 1	0.021
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.020
FHL2	four and a half LIM domains 2	0.020
JUP	junction plakoglobin	0.020
CCND1	cyclin D1	0.019
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.019
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.019
IGFBP5	insulin-like growth factor binding protein 5	0.019
PGAM1	phosphoglycerate mutase 1 (brain)	0.019
HIC1	hypermethylated in cancer 1	0.018
EPOR	erythropoietin receptor	0.016
UBQLN1	ubiquilin 1	0.016
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.016
SAMD4B	sterile alpha motif domain containing 4B	0.016
CAV1	caveolin 1, caveolae protein, 22kDa	0.016
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.016
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.015
FAF1	Fas (TNFRSF6) associated factor 1	0.015
PRKCSH	protein kinase C substrate 80K-H	0.015
RXRA	retinoid X receptor, alpha	0.015
AXIN1	axin 1	0.015
RUNX1	runt-related transcription factor 1	0.014
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.014	Rat
CANX	calnexin	0.014
PPP1R3F	protein phosphatase 1, regulatory (inhibitor) subunit 3F	0.014
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.013
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.013
PPID	peptidylprolyl isomerase D	0.013
NUMB	numb homolog (Drosophila)	0.013
TRIM32	tripartite motif containing 32	0.013
JAK1	Janus kinase 1	0.013
GOLGA8B	golgin A8 family, member B	0.013
S100A1	S100 calcium binding protein A1	0.013
FKBP4	FK506 binding protein 4, 59kDa	0.013
PILRA	paired immunoglobin-like type 2 receptor alpha	0.013
C1orf63	chromosome 1 open reading frame 63	0.012
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.012
S100A2	S100 calcium binding protein A2	0.012
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.012
SESN2	sestrin 2	0.012
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.012
DCAF7	DDB1 and CUL4 associated factor 7	0.012
ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.012
LDLR	low density lipoprotein receptor	0.012
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.012
MAGEA2	melanoma antigen family A, 2	0.012
RAB8A	RAB8A, member RAS oncogene family	0.011
COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.011
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.011
GYS2	glycogen synthase 2 (liver)	0.011
GRB14	growth factor receptor-bound protein 14	0.011
LMTK2	lemur tyrosine kinase 2	0.011
FRS2	fibroblast growth factor receptor substrate 2	0.011
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.011
GLTPD1	glycolipid transfer protein domain containing 1	0.011
EEF2	eukaryotic translation elongation factor 2	0.011
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.011
RAB5A	RAB5A, member RAS oncogene family	0.011
SH2D2A	SH2 domain containing 2A	0.011
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.011
MAP2K5	mitogen-activated protein kinase kinase 5	0.011
ACBD3	acyl-CoA binding domain containing 3	0.010
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.010
PPP5C	protein phosphatase 5, catalytic subunit	0.010
TM9SF4	transmembrane 9 superfamily protein member 4	0.010
FYN	FYN oncogene related to SRC, FGR, YES	0.010
PLD3	phospholipase D family, member 3	0.010
ATM	ataxia telangiectasia mutated	0.010
ZNF71	zinc finger protein 71	0.010
ZFYVE9	zinc finger, FYVE domain containing 9	0.010
FASN	fatty acid synthase	0.010
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.010