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Process View

Homo sapiens

8 genes annotated in human

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gland morphogenesis

GO:0022612

The process in which the anatomical structures of a gland are generated and organized.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gland morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gland morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
EGFR	epidermal growth factor receptor	1.000
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.999	Fly
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.979
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.967	Mouse
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.961	Mouse Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.958	Rat
ESR1	estrogen receptor 1	0.933	Mouse
FGFR1	fibroblast growth factor receptor 1	0.926	Mouse
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.907	Fly
FGFR2	fibroblast growth factor receptor 2	0.896	Mouse
CREBBP	CREB binding protein	0.886
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.849
FN1	fibronectin 1	0.803
NCOA1	nuclear receptor coactivator 1	0.767
NRP1	neuropilin 1	0.756	Mouse
APC	adenomatous polyposis coli	0.728
FYN	FYN oncogene related to SRC, FGR, YES	0.704	Fly
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.694	Rat
JAG1	jagged 1	0.689	Fly
RARA	retinoic acid receptor, alpha	0.633
VEGFA	vascular endothelial growth factor A	0.562	Fly
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.528
FGF1	fibroblast growth factor 1 (acidic)	0.522	Human
TGFB1	transforming growth factor, beta 1	0.474
THBS1	thrombospondin 1	0.461
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.425
PML	promyelocytic leukemia	0.424
NOTCH1	notch 1	0.323	Mouse
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.282	Fly
EP300	E1A binding protein p300	0.271
ENG	endoglin	0.239
RXRA	retinoid X receptor, alpha	0.233	Mouse
HSPG2	heparan sulfate proteoglycan 2	0.230
NCOA3	nuclear receptor coactivator 3	0.223	Mouse
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.204
NCK2	NCK adaptor protein 2	0.201
GRB2	growth factor receptor-bound protein 2	0.193
NOTCH3	notch 3	0.185
JUP	junction plakoglobin	0.184
ITGB4	integrin, beta 4	0.161
CTGF	connective tissue growth factor	0.149
GFI1B	growth factor independent 1B transcription repressor	0.139
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.136
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.127	Mouse Fly
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.126
SETD8	SET domain containing (lysine methyltransferase) 8	0.119
EHF	ets homologous factor	0.117
HNF4A	hepatocyte nuclear factor 4, alpha	0.110
S100A4	S100 calcium binding protein A4	0.107
CAV1	caveolin 1, caveolae protein, 22kDa	0.100	Mouse
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.091
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.082
FHL2	four and a half LIM domains 2	0.080
NCOA2	nuclear receptor coactivator 2	0.078
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.078	Fly
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.077
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.074	Fly
MSN	moesin	0.071
LAMB1	laminin, beta 1	0.071
PXN	paxillin	0.069
FBLN1	fibulin 1	0.063
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.061
ARHGAP1	Rho GTPase activating protein 1	0.060
COL7A1	collagen, type VII, alpha 1	0.058
PDGFA	platelet-derived growth factor alpha polypeptide	0.056	Mouse
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.056
HCK	hemopoietic cell kinase	0.053	Fly
PTK2	PTK2 protein tyrosine kinase 2	0.052
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.051
DDR1	discoidin domain receptor tyrosine kinase 1	0.051	Mouse
PDGFC	platelet derived growth factor C	0.050
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.049
EFNA1	ephrin-A1	0.047
IL4R	interleukin 4 receptor	0.046
JAK1	Janus kinase 1	0.046
IGF1R	insulin-like growth factor 1 receptor	0.045	Mouse
PGF	placental growth factor	0.044
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.044	Mouse
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.044
CDH5	cadherin 5, type 2 (vascular endothelium)	0.044
WIPF1	WAS/WASL interacting protein family, member 1	0.043
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.042
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.042	Rat
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.039
NCOR2	nuclear receptor corepressor 2	0.038
TIMP3	TIMP metallopeptidase inhibitor 3	0.038
GSK3B	glycogen synthase kinase 3 beta	0.037
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.036	Fly
STK36	serine/threonine kinase 36	0.036
DMD	dystrophin	0.036
COL1A1	collagen, type I, alpha 1	0.036
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.035	Fly
MEOX2	mesenchyme homeobox 2	0.035
HIPK2	homeodomain interacting protein kinase 2	0.034
CSNK1E	casein kinase 1, epsilon	0.032
FLNA	filamin A, alpha	0.032
FBXW11	F-box and WD repeat domain containing 11	0.030
IGFBP3	insulin-like growth factor binding protein 3	0.029
PDIA3	protein disulfide isomerase family A, member 3	0.029
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.029
MYOD1	myogenic differentiation 1	0.028
FGF10	fibroblast growth factor 10	0.028
FGF2	fibroblast growth factor 2 (basic)	0.028	Human
STAT5A	signal transducer and activator of transcription 5A	0.027	Mouse Rat
PARVA	parvin, alpha	0.026
UTRN	utrophin	0.025
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.025
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.025	Fly
VEGFC	vascular endothelial growth factor C	0.025
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.025
RB1	retinoblastoma 1	0.025
S100A2	S100 calcium binding protein A2	0.025
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.025	Mouse
MED25	mediator complex subunit 25	0.024
BAK1	BCL2-antagonist/killer 1	0.024
SUFU	suppressor of fused homolog (Drosophila)	0.023
AXIN1	axin 1	0.023
LRRK2	leucine-rich repeat kinase 2	0.023
SOX10	SRY (sex determining region Y)-box 10	0.023
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.022
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.022
FOXO1	forkhead box O1	0.022
AGRN	agrin	0.021
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.021
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.021
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.021
NCK1	NCK adaptor protein 1	0.020
GAS7	growth arrest-specific 7	0.020
FZD1	frizzled homolog 1 (Drosophila)	0.019
PPM1F	protein phosphatase, Mg2+/Mn2+ dependent, 1F	0.019
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.019
RUNX1	runt-related transcription factor 1	0.019
SPRR2A	small proline-rich protein 2A	0.018
ILK	integrin-linked kinase	0.018
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.018
THBS2	thrombospondin 2	0.018
LAT	linker for activation of T cells	0.018
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.018	Fly
GAB1	GRB2-associated binding protein 1	0.018
EZR	ezrin	0.018
VHL	von Hippel-Lindau tumor suppressor	0.018
SOX9	SRY (sex determining region Y)-box 9	0.017	Mouse
SH3KBP1	SH3-domain kinase binding protein 1	0.017
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.017
BMP7	bone morphogenetic protein 7	0.016	Mouse
LPXN	leupaxin	0.016
ESR2	estrogen receptor 2 (ER beta)	0.016
APP	amyloid beta (A4) precursor protein	0.016
SATB2	SATB homeobox 2	0.016
AR	androgen receptor	0.016	Mouse
BMP2	bone morphogenetic protein 2	0.015
CXCL12	chemokine (C-X-C motif) ligand 12	0.015
TF	transferrin	0.015
FGF7	fibroblast growth factor 7	0.015	Human
TGFBI	transforming growth factor, beta-induced, 68kDa	0.015
KITLG	KIT ligand	0.015
SPDEF	SAM pointed domain containing ets transcription factor	0.015
JAG2	jagged 2	0.015	Fly
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.015
TGFB2	transforming growth factor, beta 2	0.015
TGFB3	transforming growth factor, beta 3	0.015
SP1	Sp1 transcription factor	0.015
KANK2	KN motif and ankyrin repeat domains 2	0.014
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.014
LAMB3	laminin, beta 3	0.014
LAMA5	laminin, alpha 5	0.014	Mouse
PLCG1	phospholipase C, gamma 1	0.014
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.014
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.013
PLEC	plectin	0.013
ACTA2	actin, alpha 2, smooth muscle, aorta	0.013
EPAS1	endothelial PAS domain protein 1	0.013
EFNB2	ephrin-B2	0.013
IL6R	interleukin 6 receptor	0.012
COL2A1	collagen, type II, alpha 1	0.012
ITGB5	integrin, beta 5	0.012
ADAM15	ADAM metallopeptidase domain 15	0.012
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.012
DAXX	death-domain associated protein	0.012
COL6A1	collagen, type VI, alpha 1	0.011
SNX9	sorting nexin 9	0.011
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.011
SMAD3	SMAD family member 3	0.011
CCND1	cyclin D1	0.011
SFRP1	secreted frizzled-related protein 1	0.011	Mouse
FOXA2	forkhead box A2	0.011	Fly
MSX1	msh homeobox 1	0.011
POU3F2	POU class 3 homeobox 2	0.011
DOCK1	dedicator of cytokinesis 1	0.011
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.011
MCC	mutated in colorectal cancers	0.011
TRIP6	thyroid hormone receptor interactor 6	0.011
KRT5	keratin 5	0.010
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.010
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.010	Rat