IMP
Process View
positive regulation of smooth muscle cell proliferation
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of smooth muscle cell proliferation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.990 | Human Rat | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.961 | Human | |
| EGFR | epidermal growth factor receptor | 0.944 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.922 | ||
| NRP1 | neuropilin 1 | 0.920 | ||
| IL8 | interleukin 8 | 0.823 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.751 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.661 | ||
| CCR5 | chemokine (C-C motif) receptor 5 | 0.658 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.607 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.589 | ||
| VEGFA | vascular endothelial growth factor A | 0.547 | Human Rat | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.524 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.518 | Human | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.495 | ||
| JAG1 | jagged 1 | 0.467 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.456 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.428 | Human | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.375 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.374 | ||
| INSR | insulin receptor | 0.298 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.277 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.273 | Rat | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.251 | ||
| PGF | placental growth factor | 0.243 | Human | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.224 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.223 | Human | |
| IGF1R | insulin-like growth factor 1 receptor | 0.222 | ||
| IL1B | interleukin 1, beta | 0.218 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.203 | ||
| IRS1 | insulin receptor substrate 1 | 0.192 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.143 | ||
| NOTCH1 | notch 1 | 0.134 | ||
| DSG2 | desmoglein 2 | 0.123 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.119 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.115 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.104 | Rat | |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.098 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.097 | Human | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.097 | Human | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.096 | Human | |
| BBS10 | Bardet-Biedl syndrome 10 | 0.090 | ||
| PELI3 | pellino homolog 3 (Drosophila) | 0.079 | ||
| EPAS1 | endothelial PAS domain protein 1 | 0.075 | ||
| PLAUR | plasminogen activator, urokinase receptor | 0.075 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.072 | ||
| MYD88 | myeloid differentiation primary response gene (88) | 0.068 | Rat | |
| IL2RB | interleukin 2 receptor, beta | 0.068 | ||
| THBS1 | thrombospondin 1 | 0.068 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.067 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.066 | ||
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.064 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.064 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.062 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.062 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.060 | ||
| FGF10 | fibroblast growth factor 10 | 0.059 | ||
| S100B | S100 calcium binding protein B | 0.058 | ||
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.056 | Human | |
| TGFB3 | transforming growth factor, beta 3 | 0.055 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.054 | ||
| ESRRG | estrogen-related receptor gamma | 0.051 | ||
| PPARG | peroxisome proliferator-activated receptor gamma | 0.046 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.045 | ||
| IDE | insulin-degrading enzyme | 0.043 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.042 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.042 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.041 | ||
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.039 | ||
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.037 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.035 | ||
| TLR2 | toll-like receptor 2 | 0.033 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.033 | Human | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.033 | Rat | |
| CDK2 | cyclin-dependent kinase 2 | 0.030 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.030 | ||
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4 | 0.030 | ||
| JAK1 | Janus kinase 1 | 0.029 | ||
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.028 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.028 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.028 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.028 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.027 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.027 | ||
| STC1 | stanniocalcin 1 | 0.027 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.026 | ||
| AR | androgen receptor | 0.026 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.025 | ||
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.025 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.025 | ||
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.025 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.024 | ||
| LDLR | low density lipoprotein receptor | 0.024 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.024 | ||
| PDGFC | platelet derived growth factor C | 0.024 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.024 | Human | |
| FSTL1 | follistatin-like 1 | 0.023 | ||
| IL6R | interleukin 6 receptor | 0.023 | ||
| OCRL | oculocerebrorenal syndrome of Lowe | 0.023 | ||
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.023 | Human | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.022 | ||
| C3 | complement component 3 | 0.022 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.022 | ||
| EP300 | E1A binding protein p300 | 0.022 | ||
| EDN1 | endothelin 1 | 0.022 | ||
| MEF2A | myocyte enhancer factor 2A | 0.022 | ||
| SLA | Src-like-adaptor | 0.022 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.021 | ||
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.021 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.020 | ||
| FGF7 | fibroblast growth factor 7 | 0.020 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.020 | ||
| BCL2A1 | BCL2-related protein A1 | 0.019 | ||
| SELE | selectin E | 0.019 | ||
| JUP | junction plakoglobin | 0.019 | ||
| INHBA | inhibin, beta A | 0.019 | ||
| PLAU | plasminogen activator, urokinase | 0.019 | ||
| SOD2 | superoxide dismutase 2, mitochondrial | 0.019 | ||
| RGS3 | regulator of G-protein signaling 3 | 0.018 | ||
| MPO | myeloperoxidase | 0.018 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.018 | Human | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.017 | ||
| BMP2 | bone morphogenetic protein 2 | 0.017 | Human | |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.017 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.016 | ||
| KITLG | KIT ligand | 0.016 | ||
| IL7R | interleukin 7 receptor | 0.016 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.015 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.015 | ||
| LAT | linker for activation of T cells | 0.015 | ||
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.015 | ||
| IRS2 | insulin receptor substrate 2 | 0.015 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.015 | ||
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.015 | ||
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 | 0.014 | ||
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | 0.014 | ||
| MPEG1 | macrophage expressed 1 | 0.014 | ||
| ORC2 | origin recognition complex, subunit 2 | 0.013 | ||
| FOSL1 | FOS-like antigen 1 | 0.013 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.013 | Human | |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.013 | ||
| G0S2 | G0/G1switch 2 | 0.013 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.013 | ||
| PRMT2 | protein arginine methyltransferase 2 | 0.012 | ||
| CH25H | cholesterol 25-hydroxylase | 0.012 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.012 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.012 | Rat | |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.012 | ||
| GHR | growth hormone receptor | 0.012 | ||
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.012 | Human | |
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.012 | ||
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.012 | ||
| CD14 | CD14 molecule | 0.012 | ||
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.011 | ||
| CD163 | CD163 molecule | 0.011 | ||
| IL10 | interleukin 10 | 0.011 | ||
| VEGFC | vascular endothelial growth factor C | 0.011 | Human | |
| DLL1 | delta-like 1 (Drosophila) | 0.011 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.011 | ||
| EPHA2 | EPH receptor A2 | 0.011 | ||
| RAB22A | RAB22A, member RAS oncogene family | 0.011 | ||
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.011 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.010 | ||
| ELANE | elastase, neutrophil expressed | 0.010 | ||
| NOV | nephroblastoma overexpressed gene | 0.010 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.010 | ||
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.010 | ||
| EEA1 | early endosome antigen 1 | 0.010 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.010 | ||
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 0.010 |