IMP

Process View

Homo sapiens

38 genes annotated in human

modification of morphology or physiology of other organism involved in symbiotic interaction

The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "modification of morphology or physiology of other organism involved in symbiotic interaction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "modification of morphology or physiology of other organism involved in symbiotic interaction" (in gray)

Name	Description	Probability	Func Analog Organism
SP1	Sp1 transcription factor	0.868
SMAD3	SMAD family member 3	0.776
BCL2	B-cell CLL/lymphoma 2	0.759	Human
JUN	jun proto-oncogene	0.745
IL8	interleukin 8	0.742
BCL2L1	BCL2-like 1	0.741
RARA	retinoic acid receptor, alpha	0.691
SMAD2	SMAD family member 2	0.645	Human
CCR5	chemokine (C-C motif) receptor 5	0.504
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.360
CXCL3	chemokine (C-X-C motif) ligand 3	0.298	Mouse
RRAGC	Ras-related GTP binding C	0.293
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.265
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.227	Mouse
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.201
BAX	BCL2-associated X protein	0.182	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.168	Mouse
CXCL2	chemokine (C-X-C motif) ligand 2	0.166	Mouse
SMAD7	SMAD family member 7	0.143	Human
SMAD4	SMAD family member 4	0.137	Human
EP300	E1A binding protein p300	0.120
KDM6A	lysine (K)-specific demethylase 6A	0.118
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.104
CCL2	chemokine (C-C motif) ligand 2	0.102	Human
ATF3	activating transcription factor 3	0.101
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.096
CAV1	caveolin 1, caveolae protein, 22kDa	0.095
CCL8	chemokine (C-C motif) ligand 8	0.093	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.081
UTRN	utrophin	0.079
SOX10	SRY (sex determining region Y)-box 10	0.077
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.077
PAX3	paired box 3	0.076
DPP4	dipeptidyl-peptidase 4	0.075
IL1B	interleukin 1, beta	0.070
SMAD1	SMAD family member 1	0.068	Human
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.068
SMAD5	SMAD family member 5	0.067	Human
IL6	interleukin 6 (interferon, beta 2)	0.067
SKIL	SKI-like oncogene	0.065
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.065
ICAM1	intercellular adhesion molecule 1	0.063
CXCL5	chemokine (C-X-C motif) ligand 5	0.063	Mouse
NCOA1	nuclear receptor coactivator 1	0.061
FOXD3	forkhead box D3	0.060
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.060
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.057
DMD	dystrophin	0.056
CREBBP	CREB binding protein	0.055	Human
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.054	Human
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.054
SOX2	SRY (sex determining region Y)-box 2	0.053
CCL4	chemokine (C-C motif) ligand 4	0.052
BAK1	BCL2-antagonist/killer 1	0.050	Human
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.050
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.049
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.048
HDAC1	histone deacetylase 1	0.042
HMGA1	high mobility group AT-hook 1	0.041	Human
CCL22	chemokine (C-C motif) ligand 22	0.040	Human
CCL13	chemokine (C-C motif) ligand 13	0.040	Human
HIPK2	homeodomain interacting protein kinase 2	0.040
CCR7	chemokine (C-C motif) receptor 7	0.040
CXCL10	chemokine (C-X-C motif) ligand 10	0.039
ESR1	estrogen receptor 1	0.039
CCL7	chemokine (C-C motif) ligand 7	0.038	Human
RBBP4	retinoblastoma binding protein 4	0.038
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	0.037
BAD	BCL2-associated agonist of cell death	0.035
TNF	tumor necrosis factor	0.033
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.032	Human
CCL20	chemokine (C-C motif) ligand 20	0.032	Human
BID	BH3 interacting domain death agonist	0.032
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.032
OCIAD1	OCIA domain containing 1	0.031
CCL3	chemokine (C-C motif) ligand 3	0.031
ATF2	activating transcription factor 2	0.031	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.031
IGF1R	insulin-like growth factor 1 receptor	0.029	Human
FAM46A	family with sequence similarity 46, member A	0.029
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.029
RNF11	ring finger protein 11	0.029
TBP	TATA box binding protein	0.028
RRAGD	Ras-related GTP binding D	0.028
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.027
RAB6A	RAB6A, member RAS oncogene family	0.027
MAGEB18	melanoma antigen family B, 18	0.027
PROX1	prospero homeobox 1	0.026
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.026
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.026
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.025
KCTD17	potassium channel tetramerisation domain containing 17	0.025
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.025
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.025	Rat
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.025
ENG	endoglin	0.024
TGFBR1	transforming growth factor, beta receptor 1	0.024
IL1RN	interleukin 1 receptor antagonist	0.024
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.024
RNR2	l-rRNA	0.023
SREBF2	sterol regulatory element binding transcription factor 2	0.023
CXCL13	chemokine (C-X-C motif) ligand 13	0.023
DUSP1	dual specificity phosphatase 1	0.023
TP53	tumor protein p53	0.023
AHSG	alpha-2-HS-glycoprotein	0.023
ADAMTSL4	ADAMTS-like 4	0.023
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.022
IER2	immediate early response 2	0.022
MED25	mediator complex subunit 25	0.022
NCF4	neutrophil cytosolic factor 4, 40kDa	0.021
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.021
CCL19	chemokine (C-C motif) ligand 19	0.021	Human
EGR1	early growth response 1	0.021
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.020
STAT5A	signal transducer and activator of transcription 5A	0.020
IFNG	interferon, gamma	0.020
INSR	insulin receptor	0.020
DTNA	dystrobrevin, alpha	0.019
SIRT1	sirtuin 1	0.019
APOA2	apolipoprotein A-II	0.019
PDPK1	3-phosphoinositide dependent protein kinase-1	0.019
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.019
USP9Y	ubiquitin specific peptidase 9, Y-linked	0.018
CCL11	chemokine (C-C motif) ligand 11	0.018	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.018
SP3	Sp3 transcription factor	0.018	Human
CH25H	cholesterol 25-hydroxylase	0.017
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.017
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.017
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.017
CD83	CD83 molecule	0.017
IL10	interleukin 10	0.017
FSTL1	follistatin-like 1	0.017
ARID1A	AT rich interactive domain 1A (SWI-like)	0.017
IL1A	interleukin 1, alpha	0.017
LAT	linker for activation of T cells	0.017
IDE	insulin-degrading enzyme	0.017
HCFC1	host cell factor C1 (VP16-accessory protein)	0.017
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.017
RNF144B	ring finger protein 144B	0.017
CCR4	chemokine (C-C motif) receptor 4	0.017
TAF13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	0.017
ESRRG	estrogen-related receptor gamma	0.017
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.017
JDP2	Jun dimerization protein 2	0.017
SELE	selectin E	0.016
OSBPL9	oxysterol binding protein-like 9	0.016
YY1	YY1 transcription factor	0.016
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.016
JUNB	jun B proto-oncogene	0.016	Human
DUSP3	dual specificity phosphatase 3	0.016
HIC1	hypermethylated in cancer 1	0.016
RAB14	RAB14, member RAS oncogene family	0.016
ADAMDEC1	ADAM-like, decysin 1	0.016
THBS1	thrombospondin 1	0.016
TGFB1	transforming growth factor, beta 1	0.016
ING2	inhibitor of growth family, member 2	0.016
UBD	ubiquitin D	0.016
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.015
INADL	InaD-like (Drosophila)	0.015
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.015
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.015
BCL2A1	BCL2-related protein A1	0.015
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.015
KAT2B	K(lysine) acetyltransferase 2B	0.015
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.015
NOTCH1	notch 1	0.014
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.014
ARRB1	arrestin, beta 1	0.014
VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	0.014
CLTC	clathrin, heavy chain (Hc)	0.014
FOSL1	FOS-like antigen 1	0.014
INHBA	inhibin, beta A	0.014
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.014
MAPK14	mitogen-activated protein kinase 14	0.014
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.014
GRB10	growth factor receptor-bound protein 10	0.014
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.014
HNF1A	HNF1 homeobox A	0.013
RCOR1	REST corepressor 1	0.013
IL7R	interleukin 7 receptor	0.013
CCL1	chemokine (C-C motif) ligand 1	0.013	Human
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.013
GLTPD1	glycolipid transfer protein domain containing 1	0.013
FBXL15	F-box and leucine-rich repeat protein 15	0.013
CCR3	chemokine (C-C motif) receptor 3	0.013
BCL2L2	BCL2-like 2	0.013	Human
NCOA2	nuclear receptor coactivator 2	0.013
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.013
TCF4	transcription factor 4	0.013
MAPK3	mitogen-activated protein kinase 3	0.013
CCR1	chemokine (C-C motif) receptor 1	0.013
TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.013
APOC1	apolipoprotein C-I	0.013
STAT5B	signal transducer and activator of transcription 5B	0.013
GHR	growth hormone receptor	0.013
BIK	BCL2-interacting killer (apoptosis-inducing)	0.013
ATF7IP	activating transcription factor 7 interacting protein	0.013
BBC3	BCL2 binding component 3	0.013
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.013
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.013
POU3F2	POU class 3 homeobox 2	0.013	Human
NCOA6	nuclear receptor coactivator 6	0.013
BATF	basic leucine zipper transcription factor, ATF-like	0.013
SOX11	SRY (sex determining region Y)-box 11	0.012
ICOS	inducible T-cell co-stimulator	0.012
FGFR1	fibroblast growth factor receptor 1	0.012
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.012
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.012
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.012
PBRM1	polybromo 1	0.012
AR	androgen receptor	0.012
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.012
IL32	interleukin 32	0.012
MTA1	metastasis associated 1	0.012
MTA3	metastasis associated 1 family, member 3	0.012
RHOB	ras homolog gene family, member B	0.012
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.012
NKG7	natural killer cell group 7 sequence	0.012
CFB	complement factor B	0.012
TCF12	transcription factor 12	0.012
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.012
IL2RB	interleukin 2 receptor, beta	0.012
MEP1A	meprin A, alpha (PABA peptide hydrolase)	0.012
TP53BP2	tumor protein p53 binding protein, 2	0.012
VCAM1	vascular cell adhesion molecule 1	0.012
GLIS2	GLIS family zinc finger 2	0.012
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.011
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.011
GSTCD	glutathione S-transferase, C-terminal domain containing	0.011
PSEN1	presenilin 1	0.011
FPR3	formyl peptide receptor 3	0.011
IRF4	interferon regulatory factor 4	0.011
APOC3	apolipoprotein C-III	0.011
IRF1	interferon regulatory factor 1	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.011
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.011
NCF2	neutrophil cytosolic factor 2	0.011
SETD7	SET domain containing (lysine methyltransferase) 7	0.011
AZU1	azurocidin 1	0.011
CDCP1	CUB domain containing protein 1	0.011
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.011
GRIP1	glutamate receptor interacting protein 1	0.011
ZBED5	zinc finger, BED-type containing 5	0.011
NCOR2	nuclear receptor corepressor 2	0.011
CPN1	carboxypeptidase N, polypeptide 1	0.011
ACVR2B	activin A receptor, type IIB	0.011
DBN1	drebrin 1	0.011
KLF6	Kruppel-like factor 6	0.011
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.010
VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	0.010	Human
EBI3	Epstein-Barr virus induced 3	0.010
CALR	calreticulin	0.010
PI3	peptidase inhibitor 3, skin-derived	0.010
RUNX3	runt-related transcription factor 3	0.010
SRSF11	serine/arginine-rich splicing factor 11	0.010
TNIK	TRAF2 and NCK interacting kinase	0.010
RWDD3	RWD domain containing 3	0.010
ACVR1B	activin A receptor, type IB	0.010
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.010
MPO	myeloperoxidase	0.010
TRIM9	tripartite motif containing 9	0.010
ELN	elastin	0.010
TBC1D17	TBC1 domain family, member 17	0.010
AMBP	alpha-1-microglobulin/bikunin precursor	0.010
PRMT6	protein arginine methyltransferase 6	0.010
GOLGA1	golgin A1	0.010
APOC2	apolipoprotein C-II	0.010
PGR	progesterone receptor	0.010
MTA2	metastasis associated 1 family, member 2	0.010
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.010
HOXC8	homeobox C8	0.010
AQP9	aquaporin 9	0.010
MEOX2	mesenchyme homeobox 2	0.010